Endothelin-1 and endothelin A receptor immunoreactivity is increased in patients with diabetic nephropathy

Renal Failure

Volumn 34, Issue 3, 2012, Pages 308-315

  Zanatta, Claudete Maria ^a   Veríonese, Francisco Verssimo ^b   Da Silva Loreto, Melina ^b   Sortica, Denise A ^c   Carpio, Virna Nowotny ^b   Eldeweiss, Maria Isabel Albano ^b   Da Silva, Vinicius Duval ^d   Lopes, Tiago Giuglianni ^d   Gross, Jorge Luiz ^a,c   Canani, Luis Henrique ^a,c  

^a FEDERAL UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

^b HOSPITAL DE CLÍNICAS DE PORTO ALEGRE   (Brazil)

^c Hospital de Clnicas de Porto Alegre   (Brazil)

^d PONTIFICAL CATHOLIC UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

Author keywords

Diabetic nephropathy; Endothelin A receptor; Endothelin 1; IgA nephropathy

Indexed keywords

ENDOTHELIN 1; ENDOTHELIN A RECEPTOR;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; DIABETIC RETINOPATHY; DISEASE COURSE; FEMALE; GLOMERULUS FILTRATION RATE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOGLOBULIN A NEPHROPATHY; IMMUNOHISTOCHEMISTRY; KIDNEY BIOPSY; KIDNEY FUNCTION; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEINURIA;

ADULT; BIOLOGICAL MARKERS; BIOPSY; CROSS-SECTIONAL STUDIES; DIABETIC NEPHROPATHIES; DISEASE PROGRESSION; ENDOTHELIN-1; FEMALE; FOLLOW-UP STUDIES; HUMANS; IMMUNOHISTOCHEMISTRY; KIDNEY; MALE; MIDDLE AGED; RECEPTOR, ENDOTHELIN A; RETROSPECTIVE STUDIES;

EID: 84857575823     PISSN: 0886022X     EISSN: 15256049     Source Type: Journal    
DOI: 10.3109/0886022X.2011.647301     Document Type: Article

References (31)

1. Yanagisawa M, Kurihara H, Kimura S, et al. A novel potent vasoconstrictor peptide produced by vascular endothelial cells. Nature 1998;332:411-415.
2. Simonson MS. Endothelins: Multifunctional renal peptides. Physiol Rev. 1993;73:375-411.
3. Hopfner RL, Gopalakrishnan V. Endothelin: Emerging role in diabetic vascular complications. Diabetologia 1999;42: 1383-1394. (Pubitemid 30012308)
4. Levin ER. Endothelins. N Engl J Med. 1995;333:356-363.
5. Herizi A, Jover B, Bouriquet N, Mimran A. Prevention of the cardiovascular and renal effects of angiotensin II by endothelin blockade. Hypertension 1998;31:10-14. (Pubitemid 28124684)
6. Hargrove GM, Dufresne J, Whiteside C, Muruve DA, Wong NC. Diabetes mellitus increases endothelin-1 gene transcription in rat kidney. Kidney Int. 2000;58:1534-1545.
7. Fukui M, Nakamura T, Ebihara I, et al. Gene expression for endothelins and their receptors in glomeruli of diabetic rats. J Lab Clin Med. 1993;122:149-156. (Pubitemid 23239145)
8. Pupilli C, Brunori M, Misciglia N, et al. Presence and distribution of endothelin-1 gene expression in human kidney. Am J Physiol. 1994;267:679-687.
9. Ding SS, Qiu C, Hess P, Xi JF, Zheng N, Clozel M. Chronic endothelin receptor blockade prevents both early hyperfiltration and late overt diabetic nephropathy in the rat. J Cardiovasc Pharmacol. 2003;42:48-54. (Pubitemid 36791349)
10. Cosenzi A, Bernobich E, Trevisan R, Milutinovic N, Borri A, Bellini G. Nephroprotective effect of bosentan in diabetic rats. J Cardiovasc Pharmacol. 2003;42:752-756. (Pubitemid 37467097)
11. Lehrke I,Waldherr R, Ritz E,Wagner J. Renal endothelin-1 and endothelin receptor type B expression in glomerular diseases with proteinuria. J Am Soc Nephrol. 2001;12:2321-2329.
12. Frank K, Zeier M, Gross ML, Waldherr R, Ritz E, Amann K. Comprehensive immunohistological analysis of the endothelin system in human kidney grafts. Nephrol Dial Transplant. 2006;21:1365-1372.
13. Herman WH, Emancipator SN, Rhoten RL, Simonson MS. Vascular and glomerular expression of endothelin-1 in normal human kidney. Am J Physiol. 1998;275:8-17.
14. De Mattia G, Cassone-Faldetta M, Bellini C. Role of plasma and urinary endothelin-1 in early diabetic and hypertensive nephropathy. Am J Hypertens. 1998;11:983-988. (Pubitemid 28378413)
15. Zanatta CM, Gerchman F, Burttet L, et al. Endothelin-1 levels and albuminuria in patients with type 2 diabetes mellitus. Diabetes Res Clin Pract. 2008;80:299-304.
16. Levey AS, Coresh J, Balk E, et al. National Kidney Foundation practice guidelines for chronic kidney disease: Evaluation, classification, and stratification. Ann Intern Med. 2003;139: 137-147.
17. Junge W, Wilke B, Halabi A, Klein G. Determination of reference intervals for serum creatinine, creatinine excretion and creatinine clearance with an enzymatic and a modified Jaffe method. Clin Chim Acta. 2004;344:137-148. (Pubitemid 38626148)
18. Gundersen HJ, Bendtsen TF, Korbo L, et al. Some new, simple and efficient stereological methods and their use in pathological research and diagnosis. APMIS 1998;96:379-394.
19. Ergul A. Endothelin-1 and diabetic complications: Focus on the vasculature. Pharmacol Res. 2011;63:477-482.
20. Seligman BG, Biolo A, Polanczyk CA, Gross JL, Clausell N. Increased plasma levels of endothelin 1 and vonWillebrand factor in patients with type 2 diabetes and dyslipidemia. Diabetes Care. 2000;23:1395-1400.
21. Schneider JG, Tilly N, Hierl T. Elevated plasma endothelin-1 levels in diabetes mellitus. Am J Hypertens. 2002;15:967-972. (Pubitemid 35217402)
22. Barton M. Reversal of proteinuric renal disease and the emerging role of endothelin. Nat Clin Pract Nephrol. 2008;4:490-501.
23. Saleh MA, Boesen EI, Pollock JS, Savin VJ, Pllock DM. Endothelin receptor A-specific stimulation of glomerular inflammation and injury in a streptozocin-induced rat model of diabetes. Diabetologia 2011;54:979-988.
24. Barton M. Therapeutic potential of endothelin receptor antagonists for chronic proteinuric renal disease in humans. Biochem Biophys Acta. 2010;1802:1203-1213.
25. Mann JF, Green D, Jamerson K, et al. Avosentan for overt diabetic nephropathy. J Am Soc Nephrol. 2010;21:527-535.
26. Ohta K, Hirata Y, Shichiri M, et al. Urinary excretion of endothelin-1 in normal subjects and patients with renal disease. Kidney Int. 1991;39:307-311.
27. Benigni A, Perico N, Remuzzi G. Research on renal endothelin in proteinuric nephropathies dictates novel strategies to prevent progression. Curr Opin Nephrol Hypertens. 2001;10:1-6. (Pubitemid 32102215)
28. Chareandee C, Herman WH, Hricik DE, Simonson MS. Elevated endothelin-1 in tubular epithelium is associated with renal allograft rejection. Am J Kidney Dis. 2000;36: 541-549.
29. Drakopoulos A, Goumenos DS, Vlachojannis JG. Endothelin receptors in the kidney of patients with proteinuric and nonproteinuric nephropathies. Ren Fail. 2006;28:461-467. (Pubitemid 44277670)
30. Douglas ML, Richardson MM, Nicol DL. Endothelin axis expression is markedly different in the two main subtypes of renal cell carcinoma. Cancer 2004;100:2118-2124. (Pubitemid 38580329)
31. Hocher B, Schwarz A, Reinbacher D, et al. Effects of endothelin receptor antagonists on the progression of diabetic nephropathy. Nephron 2001;87:161-169. (Pubitemid 32215829)