Specific Mycobacterium tuberculosis T cell responses to RD1-selected peptides for the monitoring of anti-tuberculosis therapy

Scandinavian Journal of Infectious Diseases

Volumn 44, Issue 3, 2012, Pages 161-167

  Latorre, Irene ^a,b,c   Altet, Neus ^d   De Souza Galvão, Malú ^b,d   Ruiz Manzano, Joan ^a,b,c   Lacoma, Alicia ^a,b,c   Prat, Cristina ^a,b,c   Pérez, Miguel ^a   Ausina, Vicente ^a,b,c   Domínguez, Jose ^a,b,c  

^a HOSPITAL UNIVERSITARI GERMANS TRIAS I PUJOL   (Spain)

^b UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

^c INSTITUTO DE SALUD CARLOS III   (Spain)

^d Unitat de Prevenció i Control de la Tuberculosi de Barcelona   (Spain)

Author keywords

IFN assays; Immune response; Monitoring anti TB treatment; Mycobacterium tuberculosis; RD1 selected peptides

Indexed keywords

GAMMA INTERFERON; TUBERCULOSTATIC AGENT;

ARTICLE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSPOT ASSAY; FEMALE; HUMAN; LUNG TUBERCULOSIS; MAJOR CLINICAL STUDY; MALE; MYCOBACTERIUM TUBERCULOSIS; PROTEIN DOMAIN; REGION OF DIFFERENCE 1; SENSITIVITY ANALYSIS; T LYMPHOCYTE; TREATMENT OUTCOME; TREATMENT RESPONSE;

ADULT; ANTIGENS, BACTERIAL; ANTITUBERCULAR AGENTS; BACTERIAL PROTEINS; DRUG MONITORING; ENZYME-LINKED IMMUNOSPOT ASSAY; FEMALE; HUMANS; INTERFERON-GAMMA; MALE; MIDDLE AGED; MYCOBACTERIUM TUBERCULOSIS; PEPTIDES; T-LYMPHOCYTES; TUBERCULOSIS;

EID: 84857575237     PISSN: 00365548     EISSN: 16511980     Source Type: Journal    
DOI: 10.3109/00365548.2011.611167     Document Type: Article

References (38)

1. World Health Organization. Global tuberculosis control - epidemiology, strategy, financing. WHO/HTM/TB/2009. 411. Geneva, Switzerland: WHO; 2009.
2. Dominguez J, Latorre I, Altet N, Mateo L, De Souza-Galvão M, Ruiz-Manzano J, et al. IFN-gamma release assays to diagnose tuberculosis infection in the immunocompromised individual. Expert Rev Resp Med 2009;3:309-27.
3. Dominguez J, Ruiz-Manzano J, De Souza-Galvao M, Latorre I, Mila C, Blanco S, et al. Comparison of two commercially available gamma interferon blood tests for immunodiagnosis of tuberculosis. Clin Vaccine Immunol 2008;15: 168-71. (Pubitemid 351966546)
4. Ewer K, Deeks J, Alvarez L, Bryant G, Waller S, Andersen P, et al. Comparison of T-cell-based assay with tuberculin skin test for diagnosis of Mycobacterium tuberculosis infection in a school tuberculosis outbreak. Lancet 2003;361:1168-73. (Pubitemid 36398385)
5. Casas I, Latorre I, Esteve M, Ruiz-Manzano J, Rodriguez D, Prat C, et al. Evaluation of interferon-gamma release assays in the diagnosis of recent tuberculosis infection in health care workers. PLoS One 2009;4:e6686.
6. Lalvani A, Pathan AA, Durkan H, Wilkinson KA, Whelan A, Deeks JJ, et al. Enhanced contact tracing and spatial tracking of Mycobacterium tuberculosis infection by enumeration of antigen-specific T cells. Lancet 2001;357: 2017-21. (Pubitemid 32592390)
7. Latorre I, De Souza-Galvão M, Ruiz-Manzano J, Lacoma A, Prat C, Altet N, et al. Evaluating the non-tuberculous mycobacteria effect in the tuberculosis infection diagnosis. Eur Respir J 2010;35:338-42.
8. Altet-Góm ez N, De Souza-Galvao M, Latorre I, Milá C, Jimenez MA, Solsona J, et al. Diagnosing TB infection in children: analysis of discordances using in vitro tests and tuberculin skin test. Eur Respir J 2011;37:1166-74.
9. Dominguez J, De Souza-Galvao M, Ruiz-Manzano J, Latorre I, Prat C, Lacoma A, et al. T-cell responses to the Mycobacterium tuberculosis-specific antigens in active tuberculosis patients at the beginning, during, and after antituberculosis treatment. Diagn Microbiol Infect Dis 2009; 63:43-51.
10. Lalvani A. Diagnosing tuberculosis infection in the 21st century: new tools to tackle an old enemy. Chest 2007;131: 1898-906. (Pubitemid 46981652)
11. Pai M, Menzies D. Interferon-gamma release assays: what is their role in the diagnosis of active tuberculosis? Clin Infect Dis 2007;44:74-7. (Pubitemid 44968988)
12. Latorre I, De Souza-Galvao M, Ruiz-Manzano J, Lacoma A, Prat C, Fuenzalida L, et al. Quantitative evaluation of T-cell response after specific antigen stimulation in active and latent tuberculosis infection in adults and children. Diagn Microbiol Infect Dis 2009;65:236-46.
13. Andersen P, Munk ME, Pollock JM, Doherty TM. Specific immune-based diagnosis of tuberculosis. Lancet 2000;356: 1099-104.
14. Brock I, Weldingh K, Leyten EM, Arend SM, Ravn P, Andersen P. Specific T-cell epitopes for immunoassay-based diagnosis of Mycobacterium tuberculosis infection. J Clin Microbiol 2004;42:2379-87. (Pubitemid 38747478)
15. Goletti D, Vincenti D, Carrara S, Butera O, Bizzoni F, Bernardini G, et al. Selected RD1 peptides for active tuberculosis diagnosis: comparison of a gamma interferon whole-blood enzyme-linked immunosorbent assay and an enzyme-linked immunospot assay. Clin Diagn Lab Immunol 2005;12:1311-6. (Pubitemid 41626601)
16. Lalvani A. Counting antigen-specific T cells: a new approach for monitoring response to tuberculosis treatment? Clin Infect Dis 2004;38:757-9. (Pubitemid 38333875)
17. Pathan AA, Wilkinson KA, Klenerman P, McShane H, Davidson RN, Pasvol G, et al. Direct ex vivo analysis of antigen-specific IFN-gamma-secreting CD4 T cells in Mycobacterium tuberculosis-infected individuals: associations with clinical disease state and effect of treatment. J Immunol 2001;167:5217-25. (Pubitemid 33009758)
18. Lalvani A, Nagvenkar P, Udwadia Z, Pathan AA, Wilkinson KA, Shastri JS, et al. Enumeration of T cells specific for RD1-encoded antigens suggests a high prevalence of latent Mycobacterium tuberculosis infection in healthy urban Indians. J Infect Dis 2001;183:469-77. (Pubitemid 32105605)
19. Sauzullo I, Mengoni F, Lichtner M, Massetti AP, Rossi R, Iannetta M, et al. In vivo and in vitro effects of antituberculosis treatment on mycobacterial interferon-gamma T cell response. PLoS One 2009;4:e5187.
20. Ferrand RA, Bothamley GH, Whelan A, Dockrell HM. Interferon-gamma responses to ESAT-6 in tuberculosis patients early into and after anti-tuberculosis treatment. Int J Tuberc Lung Dis 2005;9:1034-9. (Pubitemid 41549192)
21. Ulrichs T, Anding R, Kaufmann SH, Munk ME. Numbers of IFN-gamma-producing cells against ESAT-6 increase in tuberculosis patients during chemotherapy. Int J Tuberc Lung Dis 2000;4:1181-3. (Pubitemid 32046299)
22. Al-Attiyah R, Mustafa AS, Abal AT, Madi NM, Andersen P. Restoration of mycobacterial antigen-induced proliferation and interferon-gamma responses in peripheral blood mononuclear cells of tuberculosis patients upon effective chemotherapy. FEMS Immunol Med Microbiol 2003;38:249-56. (Pubitemid 37289749)
23. Vincenti D, Carrara S, De Mori P, Pucillo LP, Petrosillo N, Palmieri F, et al. Identification of early secretory antigen target-6 epitopes for the immunodiagnosis of active tuberculosis. Mol Med 2003;9:105-11. (Pubitemid 36819966)
24. Carrara S, Vincenti D, Petrosillo N, Amicosante M, Girardi E, Goletti D. Use of a T cell-based assay for monitoring efficacy of antituberculosis therapy. Clin Infect Dis 2004;38:754-6. (Pubitemid 38333874)
25. SEPAR (Sociedad Española de Patología Respiratoria). [Guidelines for tuberculosis prevention]. Arch Bronconeumol 2002;38:441-51.
26. Ruiz-Manzano J, Blanquer R, Calpe JL, Caminero JA, Cayla J, Dominguez JA, et al. [Diagnosis and treatment of tuberculosis]. Arch Bronconeumol 2008;44:551-66.
27. Goletti D, Stefania C, Butera O, Amicosante M, Ernst M, Sauzullo I, et al. Accuracy of immunodiagnostic tests for active tuberculosis using single and combined results: a multicenter TBNET-Study. PLoS One 2008;3:e3417.
28. Ewer K, Millington KA, Deeks JJ, Alvarez L, Bryant G, Lalvani A. Dynamic antigen-specific T-cell responses after point-source exposure to Mycobacterium tuberculosis. Am J Respir Crit Care Med 2006;174:831-9. (Pubitemid 44511666)
29. Goletti D, Carrara S, Vincenti D, Saltini C, Rizzi EB, Schinina V, et al. Accuracy of an immune diagnostic assay based on RD1 selected epitopes for active tuberculosis in a clinical setting: a pilot study. Clin Microbiol Infect 2006;12:544-50. (Pubitemid 43740765)
30. Sauzullo I, Mengoni F, Lichtner M, Rossi R, Massetti AP, Mastroianni CM, et al. QuantiFERON-TB Gold and selected region of difference 1 peptide-based assays for the detection of Mycobacterium tuberculosis infection in a cohort of patients enrolled with suspected tuberculosis. Diagn Microbiol Infect Dis 2008;62:395-401.
31. Goletti D, Carrara S, Mayanja-Kizza H, Baseke J, Mugerwa MA, Girardi E, et al. Response to M. tuberculosis selected RD1 peptides in Ugandan HIV-infected patients with smear positive pulmonary tuberculosis: a pilot study. BMC Infect Dis 2008;8:11.
32. Millington KA, Innes JA, Hackforth S, Hinks TS, Deeks JJ, Dosanjh DP, et al. Dynamic relationship between IFNgamma and IL-2 profile of Mycobacterium tuberculosisspecific T cells and antigen load. J Immunol 2007;178: 5217-26. (Pubitemid 46595306)
33. Ruhwald M, Bodmer T, Maier C, Jepsen M, Haaland MB, Eugen-Olsen J, et al. Evaluating the potential of IP-10 and MCP-2 as biomarkers for the diagnosis of tuberculosis. Eur Respir J 2008;32:1607-15.
34. Azzurri A, Sow OY, Amedei A, Bah B, Diallo S, Peri G, et al. IFN-gamma-inducible protein 10 and pentraxin 3 plasma levels are tools for monitoring infl ammation and disease activity in Mycobacterium tuberculosis infection. Microbes Infect 2005;7:1-8. (Pubitemid 40431338)
35. Ruhwald M, Dominguez J, Latorre I, Losi M, Richeldi L, Pasticci MB, et al. A multicentre evaluation of the accuracy and performance of IP-10 for the diagnosis of infection with M. tuberculosis. Tuberculosis (Edinb) 2011;91:260-7.
36. Goletti D, Raja A, Ahamed Kabeer BS, Rodrigues C, Sodha A, Butera O, et al. IFN-gamma, but not IP-10, MCP-2 or IL-2 response to RD1 selected peptides associates to active tuberculosis. J Infect 2010;61:133-43.
37. Syed Ahamed Kabeer B, Raja A, Raman B, Thangaraj S, Leportier M, Ippolito G, et al. IP-10 response to RD1 antigens might be a useful biomarker for monitoring tuberculosis therapy. BMC Infect Dis 2011;11:135.
38. Goletti D, Parracino MP, Butera O, Bizzoni F, Casetti R, Dainotto D, et al. Isoniazid prophylaxis differently modulates T-cell responses to RD1-epitopes in contacts recently exposed to Mycobacterium tuberculosis: a pilot study. Respir Res 2007;8:5.