EGFR kinase promotes acquisition of stem cell-like properties: A potential therapeutic target in head and neck squamous cell carcinoma stem cells

PLoS ONE

Volumn 7, Issue 2, 2012, Pages

  Abhold, Eric L ^a   Kiang, Alan ^a   Rahimy, Elham ^a   Kuo, Selena Z ^a   Wang Rodriguez, Jessica ^b   Lopez, Jay Patrick ^a   Blair, Katherine J ^a   Yu, Michael Andrew ^a   Haas, Martin ^c   Brumund, Kevin T ^a   Altuna, Xabier ^d   Patel, Andrew ^a   Weisman, Robert A ^a   Ongkeko, Weg M ^a  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^d HOSPITAL DONOSTIA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

BMI1 PROTEIN; CHEMOKINE RECEPTOR CXCR4; CISPLATIN; EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR KINASE; GEFITINIB; HERMES ANTIGEN; OCTAMER TRANSCRIPTION FACTOR 4; STROMAL CELL DERIVED FACTOR 1; TRANSCRIPTION FACTOR NANOG; ANTINEOPLASTIC AGENT; EGFR PROTEIN, HUMAN; EPIDERMAL GROWTH FACTOR RECEPTOR; QUINAZOLINE DERIVATIVE;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CANCER INVASION; CANCER STEM CELL; CELL DEATH; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG POTENTIATION; DRUG SENSITIVITY; DRUG TARGETING; ENZYME ACTIVATION; HEAD AND NECK CARCINOMA; HUMAN; HUMAN CELL; IN VITRO STUDY; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INDUCTION; SQUAMOUS CELL CARCINOMA; BIOSYNTHESIS; CELL PROLIFERATION; CYTOLOGY; FLOW CYTOMETRY; HEAD AND NECK TUMOR; METABOLISM; METHODOLOGY; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

ANTIGENS, CD44; ANTINEOPLASTIC AGENTS; CARCINOMA, SQUAMOUS CELL; CELL LINE, TUMOR; CELL PROLIFERATION; CISPLATIN; FLOW CYTOMETRY; HEAD AND NECK NEOPLASMS; HUMANS; NEOPLASM INVASIVENESS; NEOPLASTIC STEM CELLS; QUINAZOLINES; RECEPTOR, EPIDERMAL GROWTH FACTOR; SIGNAL TRANSDUCTION;

EID: 84857510274     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0032459     Document Type: Article

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