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Volumn 73, Issue 1, 2012, Pages 20-25

Dehydroepiandrosterone (DHEA) improves pulmonary hypertension in chronic obstructive pulmonary disease (COPD): A pilot study

Author keywords

[No Author keywords available]

Indexed keywords

BRONCHODILATING AGENT; CALCIUM CHANNEL BLOCKING AGENT; CARBON MONOXIDE; DIURETIC AGENT; OXYGEN; PRASTERONE;

EID: 84857503172     PISSN: 00034266     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ando.2011.12.005     Document Type: Article
Times cited : (52)

References (35)
  • 1
    • 0021826734 scopus 로고
    • Gas exchange alterations in patients with chronic obstructive lung disease
    • Marthan R., Castaing Y., Manier G., Guenard H Gas exchange alterations in patients with chronic obstructive lung disease. Chest 1985, 87:470-475.
    • (1985) Chest , vol.87 , pp. 470-475
    • Marthan, R.1    Castaing, Y.2    Manier, G.3    Guenard, H.4
  • 2
    • 67649349601 scopus 로고    scopus 로고
    • Pulmonary hypertension in patients with chronic obstructive pulmonary disease: advances in pathophysiology and management
    • Barbera J.A., Blanco I. Pulmonary hypertension in patients with chronic obstructive pulmonary disease: advances in pathophysiology and management. Drugs 2009, 69:1153-1171.
    • (2009) Drugs , vol.69 , pp. 1153-1171
    • Barbera, J.A.1    Blanco, I.2
  • 3
    • 0015525705 scopus 로고
    • Patterns of cardiovascular dysfunction in chronic obstructive lung disease
    • Burrows B., Kettel L.J., Niden A.H., Rabinowitz M., Diener C.F. Patterns of cardiovascular dysfunction in chronic obstructive lung disease. N Engl J Med 1972, 286:912-918.
    • (1972) N Engl J Med , vol.286 , pp. 912-918
    • Burrows, B.1    Kettel, L.J.2    Niden, A.H.3    Rabinowitz, M.4    Diener, C.F.5
  • 5
    • 0018776388 scopus 로고
    • Predictors of mortality in chronic obstructive pulmonary disease. A 15-year follow-up study
    • Traver G.A., Cline M.G., Burrows B. Predictors of mortality in chronic obstructive pulmonary disease. A 15-year follow-up study. Am Rev Respir Dis 1979, 119:895-902.
    • (1979) Am Rev Respir Dis , vol.119 , pp. 895-902
    • Traver, G.A.1    Cline, M.G.2    Burrows, B.3
  • 6
    • 0030497896 scopus 로고    scopus 로고
    • Nitric oxide in chronic obstructive pulmonary disease
    • Barbera J.A. Nitric oxide in chronic obstructive pulmonary disease. Monaldi Arch Chest Dis 1996, 51:528-532.
    • (1996) Monaldi Arch Chest Dis , vol.51 , pp. 528-532
    • Barbera, J.A.1
  • 7
    • 0029883924 scopus 로고    scopus 로고
    • A placebo-controlled trial of prostacyclin in acute respiratory failure in COPD
    • Archer S.L., Mike D., Crow J., Long W., Weir E.K. A placebo-controlled trial of prostacyclin in acute respiratory failure in COPD. Chest 1996, 109:750-755.
    • (1996) Chest , vol.109 , pp. 750-755
    • Archer, S.L.1    Mike, D.2    Crow, J.3    Long, W.4    Weir, E.K.5
  • 9
    • 76749160426 scopus 로고    scopus 로고
    • Hemodynamic and gas exchange effects of sildenafil in patients with chronic obstructive pulmonary disease and pulmonary hypertension
    • Blanco I., Gimeno E., Munoz P.A., Pizarro S., Gistau C., Rodriguez-Roisin R., et al. Hemodynamic and gas exchange effects of sildenafil in patients with chronic obstructive pulmonary disease and pulmonary hypertension. Am J Respir Crit Care Med 2009, 181:270-278.
    • (2009) Am J Respir Crit Care Med , vol.181 , pp. 270-278
    • Blanco, I.1    Gimeno, E.2    Munoz, P.A.3    Pizarro, S.4    Gistau, C.5    Rodriguez-Roisin, R.6
  • 10
    • 0031974452 scopus 로고    scopus 로고
    • Effects of long-term oxygen therapy on pulmonary hemodynamics in COPD patients: a 6-year prospective study
    • Zielinski J., Tobiasz M., Hawrylkiewicz I., Sliwinski P., Palasiewicz G. Effects of long-term oxygen therapy on pulmonary hemodynamics in COPD patients: a 6-year prospective study. Chest 1998, 113:65-70.
    • (1998) Chest , vol.113 , pp. 65-70
    • Zielinski, J.1    Tobiasz, M.2    Hawrylkiewicz, I.3    Sliwinski, P.4    Palasiewicz, G.5
  • 11
    • 0020514279 scopus 로고
    • Long-term oxygen therapy
    • Anthonisen N.R. Long-term oxygen therapy. Ann Intern Med 1983, 99:519-527.
    • (1983) Ann Intern Med , vol.99 , pp. 519-527
    • Anthonisen, N.R.1
  • 12
    • 76549215853 scopus 로고
    • An adrenal-secreted " androgen" : dehydroisoandrosterone sulfate. Its metabolism and a tentative generalization on the metabolism of other steroid conjugates in man
    • Baulieu E.E., Corpechot C., Dray F., Emiliozzi R., Lebeau M.C., Mauvais Jarvis P., et al. An adrenal-secreted " androgen" : dehydroisoandrosterone sulfate. Its metabolism and a tentative generalization on the metabolism of other steroid conjugates in man. Recent Prog Horm Res 1965, 21:411-500.
    • (1965) Recent Prog Horm Res , vol.21 , pp. 411-500
    • Baulieu, E.E.1    Corpechot, C.2    Dray, F.3    Emiliozzi, R.4    Lebeau, M.C.5    Mauvais Jarvis, P.6
  • 13
    • 0037203495 scopus 로고    scopus 로고
    • Androgen biosynthesis from cholesterol to DHEA
    • Miller W.L. Androgen biosynthesis from cholesterol to DHEA. Mol Cell Endocrinol 2002, 198:7-14.
    • (2002) Mol Cell Endocrinol , vol.198 , pp. 7-14
    • Miller, W.L.1
  • 14
    • 0028102976 scopus 로고
    • Changes in serum concentrations of conjugated and unconjugated steroids in 40- to 80-year-old men
    • Belanger A., Candas B., Dupont A., Cusan L., Diamond P., Gomez J.L., et al. Changes in serum concentrations of conjugated and unconjugated steroids in 40- to 80-year-old men. J Clin Endocrinol Metab 1994, 79:1086-1090.
    • (1994) J Clin Endocrinol Metab , vol.79 , pp. 1086-1090
    • Belanger, A.1    Candas, B.2    Dupont, A.3    Cusan, L.4    Diamond, P.5    Gomez, J.L.6
  • 15
    • 0030739131 scopus 로고    scopus 로고
    • Marked decline in serum concentrations of adrenal C19 sex steroid precursors and conjugated androgen metabolites during aging
    • Labrie F., Belanger A., Cusan L., Gomez J.L., Candas B. Marked decline in serum concentrations of adrenal C19 sex steroid precursors and conjugated androgen metabolites during aging. J Clin Endocrinol Metab 1997, 82:2396-2402.
    • (1997) J Clin Endocrinol Metab , vol.82 , pp. 2396-2402
    • Labrie, F.1    Belanger, A.2    Cusan, L.3    Gomez, J.L.4    Candas, B.5
  • 16
    • 0037203482 scopus 로고    scopus 로고
    • Androgens and aging men
    • Baulieu E.E. Androgens and aging men. Mol Cell Endocrinol 2002, 198:41-49.
    • (2002) Mol Cell Endocrinol , vol.198 , pp. 41-49
    • Baulieu, E.E.1
  • 17
    • 0022921501 scopus 로고
    • A prospective study of dehydroepiandrosterone sulfate, mortality, and cardiovascular disease
    • Barrett-Connor E., Khaw K.T., Yen S.S. A prospective study of dehydroepiandrosterone sulfate, mortality, and cardiovascular disease. N Engl J Med 1986, 315:1519-1524.
    • (1986) N Engl J Med , vol.315 , pp. 1519-1524
    • Barrett-Connor, E.1    Khaw, K.T.2    Yen, S.S.3
  • 21
    • 0030935041 scopus 로고    scopus 로고
    • Interpreting small differences in functional status: the 6-minute-walk test in chronic lung disease patients
    • Redelmeier D.A., Bayoumi A.M., Goldstein R.S., Guyatt G.H. Interpreting small differences in functional status: the 6-minute-walk test in chronic lung disease patients. Am J Respir Crit Care Med 1997, 155:1278-1282.
    • (1997) Am J Respir Crit Care Med , vol.155 , pp. 1278-1282
    • Redelmeier, D.A.1    Bayoumi, A.M.2    Goldstein, R.S.3    Guyatt, G.H.4
  • 22
    • 0025834810 scopus 로고
    • Measuring functional status in chronic lung disease: conclusions from a randomized control trial
    • [discussion 33-17]
    • Guyatt G.H., Townsend M., Keller J., Singer J., Nogradi S. Measuring functional status in chronic lung disease: conclusions from a randomized control trial. Respir Med 1991, 85 Suppl. B:17-21. [discussion 33-17].
    • (1991) Respir Med , pp. 17-21
    • Guyatt, G.H.1    Townsend, M.2    Keller, J.3    Singer, J.4    Nogradi, S.5
  • 24
    • 0018885920 scopus 로고
    • Nocturnal oxygen therapy trial group Continuous or nocturnal oxygen therapy in hypoxemic chronic obstructive lung disease: a clinical trial
    • Nocturnal oxygen therapy trial group Continuous or nocturnal oxygen therapy in hypoxemic chronic obstructive lung disease: a clinical trial. Ann Intern Med 1980, 93:391-398.
    • (1980) Ann Intern Med , vol.93 , pp. 391-398
  • 25
    • 0021924163 scopus 로고
    • Hemodynamic response to oxygen therapy in chronic obstructive pulmonary disease
    • Timms R.M., Khaja F.U., Williams G.W. Hemodynamic response to oxygen therapy in chronic obstructive pulmonary disease. Ann Intern Med 1985, 102:29-36.
    • (1985) Ann Intern Med , vol.102 , pp. 29-36
    • Timms, R.M.1    Khaja, F.U.2    Williams, G.W.3
  • 26
    • 0036845197 scopus 로고    scopus 로고
    • Dehydroepiandrosterone treatment of women with mild-to-moderate systemic lupus erythematosus: a multicenter randomized, double-blind, placebo-controlled trial
    • Chang D.M., Lan J.L., Lin H.Y., Luo S.F. Dehydroepiandrosterone treatment of women with mild-to-moderate systemic lupus erythematosus: a multicenter randomized, double-blind, placebo-controlled trial. Arthritis Rheum 2002, 46:2924-2927.
    • (2002) Arthritis Rheum , vol.46 , pp. 2924-2927
    • Chang, D.M.1    Lan, J.L.2    Lin, H.Y.3    Luo, S.F.4
  • 27
    • 77951092239 scopus 로고    scopus 로고
    • Dehydroepiandrosterone: a new treatment for vascular remodeling diseases including pulmonary arterial hypertension
    • Dumas de la Roque E., Savineau J.P., Bonnet S. Dehydroepiandrosterone: a new treatment for vascular remodeling diseases including pulmonary arterial hypertension. Pharmacol Ther 2010, 126:186-199.
    • (2010) Pharmacol Ther , vol.126 , pp. 186-199
    • Dumas de la Roque, E.1    Savineau, J.P.2    Bonnet, S.3
  • 28
    • 4544302443 scopus 로고    scopus 로고
    • Dehydroepiandrosterone increases endothelial cell proliferation in vitro and improves endothelial function in vivo by mechanisms independent of androgen and estrogen receptors
    • Williams M.R., Dawood T., Ling S., Dai A., Lew R., Myles K., et al. Dehydroepiandrosterone increases endothelial cell proliferation in vitro and improves endothelial function in vivo by mechanisms independent of androgen and estrogen receptors. J Clin Endocrinol Metab 2004, 89:4708-4715.
    • (2004) J Clin Endocrinol Metab , vol.89 , pp. 4708-4715
    • Williams, M.R.1    Dawood, T.2    Ling, S.3    Dai, A.4    Lew, R.5    Myles, K.6
  • 29
    • 49049100968 scopus 로고    scopus 로고
    • Involvement of RhoA/Rho kinase signaling in protection against monocrotaline-induced pulmonary hypertension in pneumonectomized rats by dehydroepiandrosterone
    • Homma N., Nagaoka T., Karoor V., Imamura M., Taraseviciene-Stewart L., Walker L.A., et al. Involvement of RhoA/Rho kinase signaling in protection against monocrotaline-induced pulmonary hypertension in pneumonectomized rats by dehydroepiandrosterone. Am J Physiol Lung Cell Mol Physiol 2008, 295:L71-L78.
    • (2008) Am J Physiol Lung Cell Mol Physiol , vol.295
    • Homma, N.1    Nagaoka, T.2    Karoor, V.3    Imamura, M.4    Taraseviciene-Stewart, L.5    Walker, L.A.6
  • 30
    • 40849102385 scopus 로고    scopus 로고
    • DHEA decreases HIF-1alpha accumulation under hypoxia in human pulmonary artery cells: potential role in the treatment of pulmonary arterial hypertension
    • Dessouroux A., Akwa Y., Baulieu E.E. DHEA decreases HIF-1alpha accumulation under hypoxia in human pulmonary artery cells: potential role in the treatment of pulmonary arterial hypertension. J Steroid Biochem Mol Biol 2008, 109:81-89.
    • (2008) J Steroid Biochem Mol Biol , vol.109 , pp. 81-89
    • Dessouroux, A.1    Akwa, Y.2    Baulieu, E.E.3
  • 31
    • 70349664184 scopus 로고    scopus 로고
    • Dehydroepiandrosterone reverses systemic vascular remodeling through the inhibition of the Akt/GSK3-{beta}/NFAT axis
    • Bonnet S., Paulin R., Sutendra G., Dromparis P., Roy M., Watson K.O., et al. Dehydroepiandrosterone reverses systemic vascular remodeling through the inhibition of the Akt/GSK3-{beta}/NFAT axis. Circulation 2009, 120:1231-1240.
    • (2009) Circulation , vol.120 , pp. 1231-1240
    • Bonnet, S.1    Paulin, R.2    Sutendra, G.3    Dromparis, P.4    Roy, M.5    Watson, K.O.6
  • 32
    • 0025837793 scopus 로고
    • Survival in patients with primary pulmonary hypertension. Results from a national prospective registry
    • D'Alonzo G.E., Barst R.J., Ayres S.M., Bergofsky E.H., Brundage B.H., Detre K.M., et al. Survival in patients with primary pulmonary hypertension. Results from a national prospective registry. Ann Intern Med 1991, 115:343-349.
    • (1991) Ann Intern Med , vol.115 , pp. 343-349
    • D'Alonzo, G.E.1    Barst, R.J.2    Ayres, S.M.3    Bergofsky, E.H.4    Brundage, B.H.5    Detre, K.M.6
  • 33
    • 33747187234 scopus 로고    scopus 로고
    • Sildenafil improves hemodynamic parameters in COPD - an investigation of six patients
    • Alp S., Skrygan M., Schmidt W.E., Bastian A. Sildenafil improves hemodynamic parameters in COPD - an investigation of six patients. Pulm Pharmacol Ther 2006, 19:386-390.
    • (2006) Pulm Pharmacol Ther , vol.19 , pp. 386-390
    • Alp, S.1    Skrygan, M.2    Schmidt, W.E.3    Bastian, A.4
  • 34
    • 33646126486 scopus 로고    scopus 로고
    • A potential role for sildenafil in the management of pulmonary hypertension in patients with parenchymal lung disease
    • Madden B.P., Allenby M., Loke T.K., Sheth A. A potential role for sildenafil in the management of pulmonary hypertension in patients with parenchymal lung disease. Vascul Pharmacol 2006, 44:372-376.
    • (2006) Vascul Pharmacol , vol.44 , pp. 372-376
    • Madden, B.P.1    Allenby, M.2    Loke, T.K.3    Sheth, A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.