A placebo-controlled trial of prostacyclin in acute respiratory failure in COPD

Chest

Volumn 109, Issue 3, 1996, Pages 750-755

  Archer, Stephen L ^a,d   Mike, Debra ^a   Crow, James ^b,c   Long, Walker ^b   Weir, E Kenneth ^a  

^a UNIVERSITY OF MINNESOTA   (United States)

^b Burroughs Wellcome Co   (United States)

^c UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^d VA MEDICAL CENTER   (United States)

Author keywords

cor pulmonale; prostacyclin; pulmonary hypertension

Indexed keywords

PROSTACYCLIN DERIVATIVE;

ACUTE RESPIRATORY FAILURE; AGED; ARTICLE; ARTIFICIAL VENTILATION; CHRONIC OBSTRUCTIVE LUNG DISEASE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG EFFECT; HUMAN; INTRAVENOUS DRUG ADMINISTRATION; LUNG ARTERY PRESSURE; LUNG BLOOD FLOW; LUNG HEMODYNAMICS; LUNG VASCULAR RESISTANCE; PRIORITY JOURNAL; PULMONARY HYPERTENSION;

EID: 0029883924     PISSN: 00123692     EISSN: None     Source Type: Journal    
DOI: 10.1378/chest.109.3.750     Document Type: Article

References (20)

1. Christman B, McPherson C, Newman J, et al. An imbalance between the excretion of thromboxane and prostacyclin metabolites in pulmonary hypertension. N Engl J Med 1992; 327:70-5
2. Rubin L, Groves B, Reeves J, et al. Prostacyclin-induced acute pulmonary vasodilation in primary pulmonary hypertension. Circulation 1982; 66:334-38
3. Groves B, Rubin L, Frosolono M, et al. A comparison of the acute hemodynamic effects of prostacyclin and hydralazine in primary pulmonary hypertension. Am Heart J 1985; 110:1200-04
4. Radermacher P, Santak B, Wust HJ, et al. Prostacyclin for the treatment of pulmonary hypertension in the adult respiratory distress syndrome: effects on pulmonary capillary pressure and ventilation-perfusion distributions. Anesthesiology 1990; 72: 238-44
5. Jones K, Higenbottam T, Wallwork J. Pulmonary vasodilation with prostacyclin in primary and secondary pulmonary hypertension. Chest 1989; 96:784-89
6. Walmrath D, Schneider T, Pilch J, et al. Aerosolised prostacyclin in adult respiratory distress syndrome. Lancet 1993; 342:961-62
7. Grossman W. Blood flow measurement: the cardiac output. In: Grossman W, Baim DS, eds. Cardiac catheterization, angiography and intervention. Philadelphia: Lea & Febiger, 1991; 105-22
8. Pepka-Zaba J, Higenbottam T, Dinh-Xuan A, et al. Inhaled nitric oxide as a cause of selective pulmonary vasodilatation in pulmonary hypertension. Lancet 1991; 338:1173-74
9. Roberts JD, Polaner DM, Lang P, et al. Inhaled nitric oxide in persistent pulmonary hypertension of the newborn. Lancet 1992; 340:818-19
10. Frostell CG, Blomqvist H, Hedenstrierna C, et al. Inhaled nitric oxide selectively reverses human hypoxic pulmonary vasoconstriction without causing systemic vasodilation. Anesthesiology 1993; 78:427-35
11. Rubin L, Mendoza J, Hood M. Treatment of primary pulmonary hypertension: results of a randomized trial. Ann Intern Med 1990; 112:485-91
12. Weir E, Rubin L, Ayres S. The acute administration of vasodilators in primary pulmonary hypertension. Am Rev Respir Dis 1989; 140:1623-30
13. Frostell C, Fratacci M-D, Wain JC, et al. Inhaled nitric oxide: a selective pulmonary vasodilator reversing hypoxic pulmonary vasoconstriction. Circulation 1991; 83:2038-47
14. 2 aerosol versus nitric oxide for selective pulmonary vasodilation in hypoxic pulmonary vasoconstriction. Eur Surg Res 1993; 25:329-40
15. Colley PS, Cheney FWJ, Hlastala J. Ventilation-perfusion and gas exchange effects of sodium nitroprusside in dogs with normal and edematous lungs. Anesthesiology 1979; 50:489-95
16. Naeije R. Should pulmonary hypertension be treated in chronic obstructive pulmonary disease? In: Weir EK, Archer SL, Reeves JT, eds. The diagnosis and treatment of pulmonary hypertension. Mount Kisco, NY: Futura, 1992; 209-39
17. Wedzicha JA, Syndercombe-Court D, Tan KC. Increased platelet aggregate formation in patients with chronic airflow obstruction and hypoxaemia. Thorax 1991; 46:504-07
18. Langdon JR, McDonald TP. Effects of chronic hypoxia on platelet production in mice. Exp Hematol 1977; 5:191-98
19. Cottrell MB, Jackson CW, McDonald TP. Hypoxia increases erythropoiesis and decreases thrombocytopoiesis in mice: a comparison of two mouse strains. Proc Soc Exp Biol Med 1991; 197:261-67
20. Archer SL, Johnson GJ, Gebhard RL, et al. Effect of dietary fish oil on lung lipid profile and hypoxic pulmonary hypertension. J Appl Physiol 1989; 66:1662-73