CD133 and CD44 Cell surface markers do not identify cancer stem cells in primary human gastric tumors

Journal of Cellular Physiology

Volumn 227, Issue 6, 2012, Pages 2686-2693

  Rocco, Alba ^a   Liguori, Eleonora ^a   Pirozzi, Giuseppe ^b   Tirino, Virginia ^b   Compare, Debora ^a   Franco, Renato ^b   Tatangelo, Fabiana ^b   Palaia, Raffaele ^b   D'Armiento, Francesco Paolo ^a   Pollastrone, Giorgia ^c   Affuso, Andrea ^c   Bottazzi, Enrico Coppola ^a   Masone, Stefania ^a   Persico, Giovanni ^a   Nardone, Gerardo ^a  

^a UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^b NATIONAL CANCER INSTITUTE   (Italy)

^c Grande Ospedale Metropolitano   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CD133 ANTIGEN; CELL SURFACE MARKER; HERMES ANTIGEN;

ADULT; AGED; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER GRADING; CANCER STEM CELL; CARCINOGENESIS; CARCINOGENICITY; CLINICAL ARTICLE; FEMALE; FLOW CYTOMETRY; GASTRECTOMY; HUMAN; HUMAN TISSUE; INTESTINE CANCER; MALE; MOUSE; NONHUMAN; PHENOTYPE; PRIMARY TUMOR; PRIORITY JOURNAL; STOMACH CANCER; TUMOR XENOGRAFT;

ADULT; AGED; AGED, 80 AND OVER; ANIMALS; ANTIGENS, CD; ANTIGENS, CD44; CELL SEPARATION; FEMALE; FLOW CYTOMETRY; GASTRECTOMY; GLYCOPROTEINS; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MICE; MICE, INBRED NOD; MICE, NUDE; MICE, SCID; MIDDLE AGED; NEOPLASM TRANSPLANTATION; NEOPLASTIC STEM CELLS; PEPTIDES; STOMACH NEOPLASMS; TIME FACTORS; TUMOR CELLS, CULTURED; TUMOR MARKERS, BIOLOGICAL;

MUS; MUS MUSCULUS;

EID: 84857474200     PISSN: 00219541     EISSN: 10974652     Source Type: Journal    
DOI: 10.1002/jcp.23013     Document Type: Article

References (30)

1. Al-Hajj M, Becker MW, Wicha M, Weissman I, Clarke MF. 2004. Therapeutic implications of cancer stem cells. Curr Opin Genet Dev 14:43-47.
2. Al-Hajj M, Wicha MS, Benito-Hernandez A, Morrison SJ, Clarke MF. 2003. Prospective identification of tumorigenic breast cancer cells. Proc Natl Acad Sci USA 100:3983-3988.
3. American Cancer Society. 2007. Global cancer facts and figures.
4. Barker N, Clevers H. 2010. Leucine-rich repeat-containing G-protein-coupled receptors as markers of adult stem cells. Gastroenterology 138:1681-1696.
5. Barker N, Huch M, Kujala P, van de Wetering M, Snippert HJ, van Es JH, Sato T, Stange DE, Begthel H, van den Born M, Danenberg E, van den Brink S, Korving J, Abo A, Peters PJ, Wright N, Poulsom R, Clevers H. 2010. Lgr5(+ve) stem cells drive self-renewal in the stomach and build long-lived gastric units in vitro. Cell Stem Cell 6:25-36.
6. Collins AT, Berry PA, Hyde C, Stower MJ, Maitland NJ. 2005. Prospective identification of tumorigenic prostate cancer stem cells. Cancer Res 65:10946-10951.
7. Correa P. 1995. Helicobacter pylori and gastric carcinogenesis. Am J Surg Pathol 19:S37-S43.
8. Dalerba P, Dylla SJ, Park IK, Liu R, Wang X, Cho RW, Hoey T, Gurney A, Huang EH, Simeone DM, Shelton AA, Parmiani G, Castelli C, Clarke MF. 2007. Phenotypic characterization of human colorectal cancer stem cells. Proc Natl Acad Sci USA 104:10158-10163.
9. Fang D, Nguyen TK, Leishear K, Finko R, Kulp AN, Hotz S, Van Belle PA, Xu X, Elder DE, Herlyn M. 2005. A tumorigenic subpopulation with stem cell properties in melanomas. Cancer Res 65:9328-9337.
10. Fox JG, Wang TC. 2007. Inflammation, atrophy and gastric cancer. J Clin Invest 117:60-69.
11. Fukuda K, Saikawa Y, Ohashi M, Kumagai K, Kitajima M, Okano H, Matsuzaki Y, Kitagawa Y. 2009. Tumor initiating potential of side population cells in human gastric cancer. Int J Oncol 34:1201-1207.
12. Houghton J, Wang TC. 2005. Helicobacter pylori and gastric cancer: A new paradigm for inflammation-associated epithelial cancers. Gastroenterology 128:1567-1578.
13. Jones KH, Senft JA. 1985. An improved method to determine cell viability by simultaneous staining with fluorescein diacetate-propidium iodide. J Histochem Cytochem 33:77-79.
14. Jordan CT, Guzman ML, Noble M. 2006. Cancer stem cells. N Engl J Med 355:1253-1261.
15. Lauren P. 1965. The two histological main types of gastric carcinoma: Diffuse and so-called intestinal type carcinoma. Acta Pathol Microbiol Scand 64:31-49.
16. Li C, Heidt DG, Dalerba P, Burant CF, Zhang L, Adsay V, Wicha M, Clarke MF, Simeone DM. 2007. Identification of pancreatic cancer stem cells. Cancer Res 67:1030-1037.
17. Lichtenauer UD, Shapiro I, Geiger K, Quinkler M, Fassnacht M, Nitschke R, Rückauer KD, Beuschlein F. 2008. Side population does not define stem cell like cancer cells in the adrenocortical carcinoma cell line NCI h295R. Endocrinology 149:1314-1322.
18. Lobo NA, Shimono Y, Qian D, Clarke MF. 2007. The biology of cancer stem cells. Annu Rev Cell Dev Biol 23:675-699.
19. Ma S, Chan KW, Hu L, Lee TK, Wo JY, Ng IO, Zheng BJ, Guan XY. 2007. Identification and characterization of tumorigenic liver cancer stem/progenitor cells. Gastroenterology 132:2542-2556.
20. National Research Council. 1996. Guide for the care and use of laboratory animals. Washington, D.C.: National Academy Press.
21. O'Brien CA, Pollett A, Gallinger S, Dick JE. 2007. A human colon cancer cell capable of initiating tumour growth in immunodeficient mice. Nature 445:106-110.
22. Platet N, Mayol JF, Berger F, Hérodin F, Wion D. 2007. Fluctuation of the SP/non-SP phenotype in the C6 glioma cell line. FEBS Lett 581:1435-1440.
23. Quante M, Wang TC. 2009. Stem cells in gastroenterology and hepatology. Nat Rev Gastroenterol Hepatol 6:724-737.
24. Reya T, Morrison SJ, Clarke MF, Weissman IL. 2001. Stem cells, cancer, and cancer stem cells. Nature 414:105-111.
25. Ricci-Vitiani L, Lombardi DG, Pilozzi E, Biffoni M, Todaro M, Peschle C, De Maria R. 2007. Identification and expansion of human colon cancer initiating cells. Nature 445:111-155.
26. Singh SK, Clarke ID, Terasaki M, Bonn VE, Hawkins C, Squire J, Dirks PB. 2003. Identification of a cancer stem cell in human brain tumors. Cancer Res 63:5821-5828.
27. Takaishi S, Okumura T, Tu S, Wang SS, Shibata W, Vigneshwaran R, Gordon SA, Shimada Y, Wang TC. 2009. Identification of gastric cancer stem cells using the cell surface marker [44CD] Stem Cells 27:1006-1020.
28. Vargo-Gogola T, Rosen JM. 2007. Modelling breast cancer: One size does not fit all. Nat Rev Cancer 7:659-672.
29. Vescovi AL, Galli R, Reynolds BA. 2006. Brain tumour stem cells. Nat Rev Cancer 6:425-436.
30. Woodwart WA, Sulman EP. 2008. Cancer stem cells: Markers or biomarkers? Cancer Metastasis Rev 27:459-470.