Low serum Vitamin D concentrations in patients with schizophrenia

Israel Medical Association Journal

Volumn 14, Issue 2, 2012, Pages 88-92

  Itzhaky, Dganit ^a   Amital, Daniela ^b,d   Gorden, Katya ^d   Bogomolni, Alisa ^a   Arnson, Yoav ^c,d   Amital, Howard ^c,d  

^a MEIR MEDICAL CENTER   (Israel)

^b NESS ZIONA MENTAL HEALTH CENTER   (Israel)

^c SHEBA MEDICAL CENTER   (Israel)

^d TEL AVIV UNIVERSITY   (Israel)

Author keywords

Autoimmune diseases; Depression; Schizophrenia; Vitamin D

Indexed keywords

ANTIDEPRESSANT AGENT; CARDIOLIPIN ANTIBODY; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; MOOD STABILIZER; NEUROLEPTIC AGENT; SEDATIVE AGENT; VITAMIN D;

ADULT; AGED; ANTIBODY TITER; ARTICLE; BLOOD SAMPLING; CONTROLLED STUDY; CORRELATION ANALYSIS; DEPRESSION; DISEASE ACTIVITY; FEMALE; FOOD COMPOSITION; HAMILTON SCALE; HUMAN; IMMUNOASSAY; MAJOR CLINICAL STUDY; MAJOR DEPRESSION; MALE; POSITIVE AND NEGATIVE SYNDROME SCALE; SCHIZOPHRENIA; SUN EXPOSURE; VITAMIN BLOOD LEVEL; VITAMIN D BLOOD LEVEL;

ADULT; AGED; ANALYSIS OF VARIANCE; DEPRESSIVE DISORDER, MAJOR; FEMALE; HUMANS; IMMUNOASSAY; MALE; MIDDLE AGED; PSYCHIATRIC STATUS RATING SCALES; SCHIZOPHRENIA; VITAMIN D; VITAMIN D DEFICIENCY; YOUNG ADULT;

EID: 84857423417     PISSN: 15651088     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (25)

1. Arnson Y, Amital H, Shoenfeld Y. Vitamin 1. D and autoimmunity: new aetiological and therapeutic considerations. Ann Rheum Dis 2007; 66: 1137-42.
2. Holick MF. Vitamin D deficiency. N Engl J Med 2007; 357: 266-81.
3. Autier P, Gandini S. Vitamin D supplementation and total mortality: a metaanalysis of randomized controlled trials. Arch Intern Med 2007; 167: 1730-7.
4. Giovannucci E. Epidemiological evidence for vitamin D and colorectal cancer. J Bone Miner Res 2007; 22 (Suppl 2): V81-5.
5. Giovannucci E, Liu Y, Hollis BW, Rimm EB. 25-hydroxyvitamin D and risk of myocardial infarction in men: a prospective study. Arch Intern Med 2008; 168: 1174-80.
6. Amital H, Szekanecz Z, Szucs G, et al. Serum concentrations of 25-OH vitamin D in patients with systemic lupus erythematosus (SLE) are inversely related to disease activity: is it time to routinely supplement patients with SLE with vitamin D? Ann Rheum Dis 2010; 69: 1155-7.
7. Arnson Y, Amital H, Agmon-Levin N, et al. Serum 25-OH vitamin D concentrations are linked with various clinical aspects in patients with systemic sclerosis: a retrospective cohort study and review of the literature. Autoimmun Rev 2011; 10: 490-4
8. Munger KL, Levin LI, Hollis BW, Howard NS, Ascherio A. Serum 25-hydroxyvitamin D levels and risk of multiple sclerosis. JAMA 2006; 296: 2832-8.
9. Eyles DW, Feron F, Cui X, et al. Developmental vitamin D deficiency causes abnormal brain development. Psychoneuroendocrinology 2009; 34 (Suppl 1): S247-57.
10. Amital H, Shoenfeld Y. Autoimmunity and schizophrenia: an epiphenomenon or an etiology? Isr J Med Sci 1993; 29: 593-7.
11. Goldsmith CA, Rogers DP. The case for autoimmunity in the etiology of schizophrenia. Pharmacotherapy 2008; 28: 730-41.
12. Sirota P, Bogdanov I, Katzav A, Hershko R, Chapman J. Reduced anticardiolipin antibodies in first episode and chronic schizophrenia. Psychiatry Res 2006; 144: 211-16.
13. Spivak B, Radwan M, Bartur P, Mester R, Weizman A. Antinuclear autoantibodies in chronic schizophrenia. Acta Psychiatr Scand 1995; 92: 266-9.
14. Strous RD, Shoenfeld Y. Schizophrenia, autoimmunity and immune system dysregulation: a comprehensive model updated and revisited. J Autoimmun 2006; 27: 71-80.
15. Kay SR, Opler LA, Lindenmayer JP. Reliability and validity of the positive and negative syndrome scale for schizophrenics. Psychiatry Res 1988; 23: 99-110.
16. Hamilton M. A rating scale for depression. J Neurol Neurosurg Psychiatry 1960; 23: 56-62.
17. Sawa A, Snyder SH. Schizophrenia: diverse approaches to a complex disease. Science 2002; 296: 692-5.
18. Cherniack EP, Troen BR, Florez HJ, Roos BA, Levis S. Some new food for thought: the role of vitamin D in the mental health of older adults. Curr Psychiatry Rep 2009; 11: 12-19.
19. McGrath JJ, Eyles DW, Pedersen CB, et al. Neonatal vitamin d status and risk of schizophrenia: a population-based case-control study. Arch Gen Psychiatry 2010; 67: 889-94.
20. McGrath J. Hypothesis: is low prenatal vitamin D a risk-modifying factor for schizophrenia? Schizophr Res 1999; 40: 173-7.
21. Hummer M, Malik P, Gasser RW, et al. Osteoporosis in patients with schizophrenia. Am J Psychiatry 2005; 162: 162-7.
22. Schneider B, Weber B, Frensch A, Stein J, Fritz J. Vitamin D in schizophrenia, major depression and alcoholism. J Neural Transm 2000; 107: 839-42.
23. Oren Y, Shapira Y, Agmon-Levin N, et al. Vitamin D insufficiency in a sunny environment: a demographic and seasonal analysis. IMAJ Isr Med Assoc J 2010; 12: 751-6.
24. Nieves J, Cosman F, Herbert J, Shen V, Lindsay R. High prevalence of vitamin D deficiency and reduced bone mass in multiple sclerosis. Neurology 1994; 44: 1687-92.
25. Curkendall SM, Mo J, Glasser DB, Rose SM, Jones JK. Cardiovascular disease in patients with schizophrenia in Saskatchewan, Canada. J Clin Psychiatry 2004; 65: 715-20.