The Alzheimer's disease related tau protein as a new target for chemical protein engineering

Chemistry - A European Journal

Volumn 18, Issue 9, 2012, Pages 2488-2492

  Broncel, Malgorzata ^a   Krause, Eberhard ^b   Schwarzer, Dirk ^c   Hackenberger, Christian P R ^a  

^a FREIE UNIVERSITÄT BERLIN   (Germany)

^b LEIBNIZ INSTITUT FÜR MOLEKULARE PHARMAKOLOGIE   (Germany)

^c UNIVERSITY OF TÜBINGEN   (Germany)

Author keywords

alzheimer's disease; phosphorylation; protein engineering; self assembly; tau protein

Indexed keywords

ALZHEIMER'S DISEASE; PHOSPHORYLATION SITES; PROTEIN ENGINEERING; TAU PROTEINS;

BIOCHEMICAL ENGINEERING; DISEASES; GENETIC ENGINEERING; PROTEINS;

PHOSPHORYLATION;

TAU PROTEIN;

ALZHEIMER DISEASE; ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; HUMAN; METABOLISM; PATHOLOGY; PHOSPHORYLATION; PROTEIN ENGINEERING;

ALZHEIMER DISEASE; HUMANS; MOLECULAR STRUCTURE; PHOSPHORYLATION; PROTEIN ENGINEERING; TAU PROTEINS;

EID: 84857399129     PISSN: 09476539     EISSN: 15213765     Source Type: Journal    
DOI: 10.1002/chem.201103032     Document Type: Article

References (28)

1. M. D. Weingarten, A. H. Lockwood, S. Y. Hwo, M. W. Kirschner, Proc. Natl. Acad. Sci. USA 1975, 72, 1858-1862.
2. A. Alonso, T. Zaidi, I. Grundke-Iqbal, K. Iqbal, Proc. Natl. Acad. Sci. USA 1994, 91, 5562-5566.
3. A. Alonso, T. Zaidi, M. Novak, I. Grundke-Iqbal, K. Iqbal, Proc. Natl. Acad. Sci. USA 2001, 98, 6923-6928.
4. C. X. Gong, F. Liu, I. Grundke-Iqbal, K. Iqbal, J. Biomed. Biotechnol. 2006, 2006, 31825.
5. C. X. Gong, F. Liu, I. Grundke-Iqbal, K. Iqbal, J. Neural Transm. 2005, 112, 813-838.
6. L. X. Zhou, Z. Y. Zeng, J. T. Du, Y. F. Zhao, Y. M. Li, Biochem. Biophys. Res. Commun. 2006, 348, 637-642.
7. M. Inoue, A. Hirata, K. Tainaka, T. Morii, T. Konno, Biochemistry 2008, 47, 11847-11857.
8. C. Smet-Nocca, M. Broncel, J. M. Wieruszeski, C. Tokarski, X. Hanoulle, A. Leroy, I. Landrieu, C. Rolando, G. Lippens, C. P. R. Hackenberger, Mol. Biosyst. 2011, 7, 1420-1429.
9. S. Jeganathan, A. Hascher, S. Chinnathambi, J. Biernat, E. M. Mandelkow, E Mandelkow, J. Biol. Chem. 2008, 283, 32066-32076.
10. H. Ding, T. A. Matthews, G. V. W. Johnson, J. Biol. Chem. 2006, 281, 19107-19114.
11. M. Goedert, R. Jakes, R. A. Crowther, P. Cohen, E. Vanmechelen, M. Vandermeeren, P. Cras, Biochem. J. 1994, 301, 871-877.
12. I. Landrieu, L. Lacosse, A. Leroy, J. M. Wieruszeski, X. Trivelli, A. Sillen, N. Sibille, H. Schwalbe, K. Saxena, T. Langer, G. Lippens, J. Am. Chem. Soc. 2006, 128, 3575-3583.
13. M. Goedert, R. Jakes, EMBO J. 1990, 9, 4225-4230.
14. N. Csokova, R. Skrabana, H. D. Liebig, A. Mederlyova, P. Kontsek, M. Novak, Protein Expression Purif. 2004, 35, 366-372 and references therein.
15. T. W. Muir, D. Sondhi, P. A. Cole, Proc. Natl. Acad. Sci. USA 1998, 95, 6705-6710.
16. T. Li, C. Hawkes, H. Y. Qureshi, S. Kar, H. K. Paudel, Biochemistry 2006, 45, 3134-3145.
17. P. E. Dawson, T. W. Muir, I. Clark-Lewis, S. B. Kent, Science 1994, 266, 776-779.
18. C. P. Hackenberger, D. Schwarzer, Angew. Chem. Int. Ed. 2008, 47, 10030-10074.
19. T. W. Muir, Annu. Rev. Biochem. 2003, 72, 249-289.
20. M. Huse, M. N. Holford, J. Kuriyan, T. W. Muir, J. Am. Chem. Soc. 2000, 122, 8337-8338.
21. J. W. Wu, M. Hu, J. Chai, J. Seoane, M. Huse, C. Li, D. J. Rigotti, S. Kyin, T. W. Muir, R. Fairman, J. Massague, Y. Shi, Mol. Cell 2001, 8, 1277-1289.
22. M. E. Hahn, T. W. Muir, Angew. Chem. 2004, 116, 5924-5927
23. Angew. Chem. Int. Ed. 2004, 43, 5800-5803.
24. M. L. Lesaicherre, R. Y. Lue, G. Y. Chen, Q. Zhu, S. Q. Yao, J. Am. Chem. Soc. 2002, 124, 8768-8769.
25. K. Holland-Nell, A. G. Beck-Sickinger, ChemBioChem 2007, 8, 1071-1076.
26. T. M. Hackeng, J. H. Griffin, P. E. Dawson, Proc. Natl. Acad. Sci. USA 1999, 96, 10068-10073.
27. A. Leroy, I. Landrieu, I. Huvent, D. Legrand, B. Codeville, J. M. Wieruszeski, G. Lippens, J. Biol. Chem. 2010, 285, 33435-33444.
28. A. Abraha, N. Ghoshal, T. C. Gamblin, V. Cryns, R. W. Berry, J. Kuret, L. I. Binder, J. Cell Sci. 2000, 113, 3737-3745.