Defining substrate and blocker activity of alanine-serine- cysteine transporter 2 (ASCT2) ligands with novel serine analogs

Molecular Pharmacology

Volumn 81, Issue 3, 2012, Pages 356-365

  Albers, Thomas ^a   Marsiglia, William ^a   Thomas, Taniya ^a   Gameiro, Armanda ^a   Grewer, Christof ^a  

^a BINGHAMTON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

(S) 1 CARBOXY 2 ((CYCLOHEXANECARBONYL)OXY)ETHANAMINIUM)TRIS (2,2,2 TRIFLUOROACETATE); (S) 3 (TERT BUTOXY) 2 ((TERT BUTOXYCARBONYL)AMINO) 3 OXOPROPYL 2 NAPHTHOATE; (S) 3 (TERT BUTOXY) 2 ((TERT BUTOXYCARBONYL)AMINO) 3 OXOPROPYL [1,1' BIPHENYL] 4 CARBOXYLATE; (S) 3 (TERT BUTOXY) 2 ((TERT BUTOXYCARBONYL)AMINO) 3 OXOPROPYLCYCLOHEXANECARBOXYLATE; (S) TERT BUTYL 2 (TERT BUTOXYCARBONYL)AMINO) 3 (ISOBUTYRYLOXY)PROPANOATE; (S) TERT BUTYL 2 (TERT BUTOXYCARBONYL)AMINO) 3 (PROPIONYLOXY)PROPANOATE; (S) TERT BUTYL 3 (2 (9H FLUOREN 3 YL)ACETOXY) 2 ((TERT BUTOXYCARBONYL)AMINO)PROPANOATE; ALANINE SERINE CYSTEINE TRANSPORTER 2; ALANINE SERINE CYSTEINE TRANSPORTER 2 INHIBITOR; AMINO ACID DERIVATIVE; AMINO ACID TRANSPORTER; BIPHENYL DERIVATIVE; CARBOXYLIC ACID DERIVATIVE; LEVO SERINE ESTER SERINE BIPHENYL 4 CARBOXYLATE; PROTEIN INHIBITOR; SERINE DERIVATIVE; SERINE PROTEINASE; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; BINDING SITE; DRUG ACTIVITY; DRUG BINDING; DRUG STRUCTURE; DRUG SYNTHESIS; HYDROPHOBICITY; MOLECULAR DOCKING; PRIORITY JOURNAL; PROTEIN FUNCTION; STRUCTURE ACTIVITY RELATION;

AMINO ACID TRANSPORT SYSTEM ASC; ANIMALS; LIGANDS; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; RATS; SERINE; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY;

EID: 84857386481     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.111.075648     Document Type: Article

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