ImageStream promyelocytic leukemia protein immunolocalization: In search of promyelocytic leukemia cells

Cytometry Part A

Volumn 81 A, Issue 3, 2012, Pages 232-237

  Mirabelli, Peppino ^a,b   Scalia, Giulia ^a   Pascariello, Caterina ^a,b   D'Alessio, Francesca ^a,b   Mariotti, Elisabetta ^a   Noto, Rosa Di ^a,b   George, Thaddeus C ^c   Kong, Raymond ^c   Venkatachalam, Vidya ^c   Basiji, David ^c   Vecchio, Luigi Del ^a,b  

^a CEINGE BIOTECNOLOGIE AVANZATE   (Italy)

^b UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^c Amnis Corporation   (United States)

Author keywords

Acute promyelocytic leukemia; All trans retinoic acid; Flow cytometry; ImageStream; PML gene

Indexed keywords

NUCLEAR PROTEIN; PML PROTEIN, HUMAN; TRANSCRIPTION FACTOR; TUMOR PROTEIN; TUMOR SUPPRESSOR PROTEIN;

ARTICLE; CHEMISTRY; FLOW CYTOMETRY; GRANULOCYTE PRECURSOR; HUMAN; IMAGE CYTOMETRY; METHODOLOGY; PHYSIOLOGY; PROMYELOCYTIC LEUKEMIA; STAINING; TISSUE FIXATION; TUMOR CELL LINE;

CELL LINE, TUMOR; FLOW CYTOMETRY; GRANULOCYTE PRECURSOR CELLS; HUMANS; IMAGE CYTOMETRY; LEUKEMIA, PROMYELOCYTIC, ACUTE; NEOPLASM PROTEINS; NUCLEAR PROTEINS; STAINING AND LABELING; TISSUE FIXATION; TRANSCRIPTION FACTORS; TUMOR SUPPRESSOR PROTEINS;

EID: 84857369761     PISSN: 15524922     EISSN: 15524930     Source Type: Journal    
DOI: 10.1002/cyto.a.22013     Document Type: Article

References (14)

1. Degos L. The history of acute promyelocytic leukemia. Br J Haematol 2003; 122: 539-553.
2. Ferrara F. Acute promyelocytic leukemia: What are the treatment options? Expert Opin Pharmacother 2010; 11: 587-596.
3. Lo-Coco F, Ammatuna E. The biology of acute promyelocytic leukemia and its impact on diagnosis and treatment. Hematol Am Soc Hematol Educ Prog 2006; 514: 156-161.
4. Villamor N, Costa D, Aymerich M, Esteve J, Carrió A, Rozman M, Aguilar JL, Falini B, Montserrat E, Campo E, Colomer D. Rapid diagnosis of acute promyelocytic leukemia by analyzing the immunocytochemical pattern of the PML protein with the monoclonal antibody PG-M3. Am J Clin Pathol 2000; 114: 786-792.
5. Di Noto R, Mirabelli P, Del Vecchio L. Flow cytometry analysis of acute promyelocytic leukemia: The power of 'surface hematology'. Leukemia 2007; 21: 4-8.
6. Ossenkoppele GJ, van de Loosdrecht AA, Schuurhuis GJ. Review of the relevance of aberrant antigen expression by flow cytometry in myeloid neoplasms. Br J Haematol 2011; 153: 421-436.
7. Grimwade L, Gudgin E, Bloxham D, Scott MA, Erber WN. PML protein analysis using imaging flow cytometry. J Clin Pathol 2010; 64: 447-450.
8. Basiji DA, Ortyn WE, Liang L, Venkatachalam V, Morrissey P. Cellular image analysis and imaging by flow cytometry. Clin Lab Med 2007; 27: 653-670.
9. UKCCCR guidelines for the use of cell lines in cancer research. Br J Cancer 2000; 82: 1495-1509.
10. Grimwade D, Lo Coco F. Acute promyelocytic leukemia: A model for the role of molecular diagnosis and residual disease monitoring in directing treatment approach in acute myeloid leukemia. Leukemia 2002; 16: 1959-1973.
11. Peters JM, Ansari MQ. Multiparameter flow cytometry in the diagnosis and management of acute leukemia. Arch Pathol Lab Med 2011; 135: 44-54.
12. Paietta E. Expression of cell-surface antigens in acute promyelocytic leukemia. Best Pract Res Clin Haematol 2003; 16: 369-385.
13. Dong HY, Kung JX, Bhardwaj V, McGill J. Flow cytometry rapidly identifies all acute promyelocytic leukemias with high specificity independent of underlying cytogenetic abnormalities. Am J Clin Pathol 2011; 135: 76-84.
14. Dimov ND, Medeiros LJ, Kantarjian HM, Cortes JE, Chang KS, Bueso-Ramos CE, Ravandi F. Rapid and reliable confirmation of acute promyelocytic leukemia by immunofluorescence staining with an antipromyelocytic leukemia antibody: The M. D. Anderson Cancer Center experience of 349 patients. Cancer 2010; 116: 369-376.