NAC1 modulates sensitivity of ovarian cancer cells to cisplatin by altering the HMGB1-mediated autophagic response

Oncogene

Volumn 31, Issue 8, 2012, Pages 1055-1064

  Zhang, Y ^a,b   Cheng, Y ^a   Ren, X ^a   Zhang, L ^b   Yap, K L ^c   Wu, H ^d   Patel, R ^d   Liu, D ^a   Qin, Z H ^b   Shih, I M ^c   Yang, J M ^a,b  

^a PENN STATE COLLEGE OF MEDICINE   (United States)

^b SOOCHOW UNIVERSITY   (China)

^c JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d RUTGERS ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

Author keywords

apoptosis; autophagy; cisplatin; HMGB1; NAC1; ovarian cancer

Indexed keywords

CISPLATIN; HIGH MOBILITY GROUP B1 PROTEIN; NUCLEAR FACTOR; NUCLEUS ACCUMBENS 1 PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; AUTOPHAGY; CANCER CELL CULTURE; CONTROLLED STUDY; DRUG EFFECT; DRUG SENSITIVITY; HUMAN; HUMAN CELL; OVARY CANCER; PRIORITY JOURNAL; PROTEIN FUNCTION;

ADENOSINE; ANTINEOPLASTIC AGENTS, ALKYLATING; AUTOPHAGY; CELL LINE, TUMOR; CELL SURVIVAL; CHLOROQUINE; CISPLATIN; DRUG RESISTANCE, NEOPLASM; FEMALE; GENE EXPRESSION; GENE KNOCKDOWN TECHNIQUES; HMGB1 PROTEIN; HUMANS; MICROTUBULE-ASSOCIATED PROTEINS; NEOPLASM PROTEINS; OVARIAN NEOPLASMS; PROTEIN TRANSPORT; REPRESSOR PROTEINS; RNA INTERFERENCE; RNA-BINDING PROTEINS;

EID: 84857368699     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2011.290     Document Type: Article

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