The promoter of the serotonin transporter genotype, environment and depression: A hypothesis supported?

Journal of Affective Disorders

Volumn 137, Issue 1-3, 2012, Pages 1-3

  Brown, George W ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

SEROTONIN TRANSPORTER;

ALLELE; CHILD ABUSE; DEPRESSION; GENOTYPE; GENOTYPE ENVIRONMENT INTERACTION; HUMAN; PRIORITY JOURNAL; REVIEW; RISK FACTOR;

EID: 84857363058     PISSN: 01650327     EISSN: 15732517     Source Type: Journal    
DOI: 10.1016/j.jad.2011.09.015     Document Type: Editorial

References (23)

1. J. Belsky, C. Jonassaint, M. Pluess, M. Stanton, B. Brummett, and R. Williams Vulnerability genes or plasticity genes? Molecular Psychiatry 13 2009 1070 1078
2. A. Bifulco, G.W. Brown, and T.O. Harris Childhood experience of care and abuse (CECA): a retrospective interview measure Child Psychology and Psychiatry 35 1994 1491-1435
3. G.W. Brown Depression G.W. Brown, T. Harris, Life Events and Illness 1989 The Guilford Press New York 49 93
4. G.W. Brown Childhood maltreatment and adult psychopathology: some measurement options S.R.H. Beach, M.Z. Wamboldt, N.J. Kaslow, R.E. Heyman, M.B. First, L.G. Underwood, D. Reiss, Relational Processes and DSM-V: Neuroscience, Assessment, Prevention and Intervention 2006 American Psychiatric Association Washington, DC
5. G.W. Brown, and T.O. Harris Depression and the serotonin transporter 5-HTTLPR polymorphism: a review and a hypothesis concerning gene-environment interaction Journal of Affective Disorders 111 2008 1 12
6. G.W. Brown, and P. Moran Clinical and psychosocial origins of chronic depressive episodes. 1: a community survey The British Journal of Psychiatry 165 1994 447 456 (Pubitemid 24305952)
7. G.W. Brown, T.O. Harris, C. Hepworth, and R. Robinson Clinical and psychosocial origins of chronic depressive episodes. 2: A patient enquiry The British Journal of Psychiatry 165 1994 457 465 (Pubitemid 24305953)
8. G.W. Brown, T.K.J. Craig, T.O. Harris, R.V. Handley, and A.L. Harvey Development of a retrospective interview measure of parental maltreatment using the Childhood Experience of Care & Abuse (CECA) instrument - a life-course study of adult chronic depression - 1 Journal of Affective Disorders 103 2007 205 215 (Pubitemid 47449707)
9. G.W. Brown, T.K.J. Craig, T.O. Harris, R.V. Handley, and A.L. Harvey Validity of retrospective measures of early maltreatment and depressive episodes using the Childhood Experience of Care & Abuse (CECA) instrument - a life-course study of adult chronic depression - 2 Journal of affective disorders 103 2007 217 224 (Pubitemid 47449708)
10. G.W. Brown, T.K. Craig, and T.O. Harris Parental maltreatment and proximal risk factors using the Childhood Experience of Care & Abuse (CECA) instrument: a life-course study of adult chronic depression - 5 Journal of affective disorders 110 2008 222 233
11. A. Caspi, K. Sugden, T.E. Moffitt, A. Taylor, I.W. Craig, H. Harrington, J. McClay, J. Mill, J. Martin, A. Braithwaite, and R. Poulton Influence of life stress on depression: moderation by a polymorphism in the 5-H TT gene Science 301 2003 386 389 (Pubitemid 36877077)
12. J.R. Homberg, and K.-P. Lesch Looking on the bright side of serotonin transporter variation Biological Psychiatry 69 2011 513 519
13. K. Karg, M. Burmeister, K. Shedden, and S. Sen The serotonin transporter promoter variant (5-HTTLPR), stress, and depression meta-analysis revisited Archives of General Psychiatry 68 2011 444 454
14. J. Kaufman, B.Z. Yang, H. Douglas-Palumberi, D. Grasso, D. Lipschitz, S. Houshyar, J.H. Krystal, and Gelernter Brain-derived neurotrophic factor-5-HTTLPR gene interactions and environmental modifiers of depression in children Biological Psychiatry 59 2006 673 680
15. E. Sibille, and D.A. Lewis SERT-ainly involved in depression, but when? The American Journal of Psychiatry 163 2006 8 10
16. R.L. Sjoberg, K.W. Nilsson, N. Nordquist, J. Ohrvik, J. Leppert, L. Lindstrom, and L. Oreland Development of depression: sex and interaction between environment and a promoter polymorphism of the serotonin transporter gene International Journal of Neuropsychopharmacology 9 2006 443 449 (Pubitemid 43979704)
17. N. Risch, R. Herrell, T. Lehner, K. Liang, L. Eaves, J. Hoh, A. Griem, M. Kovas, J. Ott, and K.R. Merikangas Interaction between the serotonin transporter gene (5-HTTLPR), stressful life events, and risk of depression: a meta analysis JAMA 301 2009 2462 2471
18. R. Uher The implications of gene-environment interactions in depression: will cause inform cure? Molecular Psychiatry 13 2008 1070 1078
19. R. Uher, and P. McGuffin The moderation by the serotonin transporter gene of environmental adversity in the aetiology of mental illness: review and methodological analysis Molecular Psychiatry 13 2008 131 146
20. R. Uher, and P. McGuffin The moderation by the serotonin transporter gene of environmental adversity in the etiology of depression Molecular Psychiatry 15 2010 18 22
21. R. Uher, A. Caspi, R. Houts, K. Sugden, B. Williams, R. Poulton, and T.E. Moffitt Serotonin transporter gene moderates childhood maltreatment's effect on persistent but not single-episode depression: replications and implications for resolving inconsistent results Journal of Affective Disorders 2011
22. K. Wilhelm, P.B. Mitchell, H. Niven, A. Finch, L. Wedgwood, A. Scimone, I.P. Blair, G. Parker, and P.R. Schofield Life events, first depression onset and the serotonin transporter gene The British Journal of Psychiatry 188 2006 210 215 (Pubitemid 43341646)
23. J.K. Wing, T. Barbor, and T.S. Brugha Scan: schedule for clinical assessment in neuropsychiatry Archives of General Psychiatry 47 1990 587 593