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Volumn 30, Issue 12, 2012, Pages 2116-2124

CD40 triggering induces strong cytotoxic T lymphocyte responses to heat-killed Staphylococcus aureus immunization in mice: A new vaccine strategy for staphylococcal mastitis

Author keywords

CD40; Cytotoxic T cells; Staphylococcal mastitis

Indexed keywords

CD40 LIGAND MONOCLONAL ANTIBODY; STAPHYLOCOCCUS VACCINE;

EID: 84857361687     PISSN: 0264410X     EISSN: 18732518     Source Type: Journal    
DOI: 10.1016/j.vaccine.2012.01.039     Document Type: Article
Times cited : (15)

References (51)
  • 1
    • 34047219715 scopus 로고    scopus 로고
    • Economic effects of bovine mastitis and mastitis management: a review
    • Halasa T., Huijps K., Osteras O., Hogeveen H. Economic effects of bovine mastitis and mastitis management: a review. Vet Q 2007, 29:18-31.
    • (2007) Vet Q , vol.29 , pp. 18-31
    • Halasa, T.1    Huijps, K.2    Osteras, O.3    Hogeveen, H.4
  • 3
    • 0031255898 scopus 로고    scopus 로고
    • Bovine mastitis pathogens in New York and Pennsylvania: prevalence and effects on somatic cell count and milk production
    • Wilson D.J., Gonzalez R.N., Das H.H. Bovine mastitis pathogens in New York and Pennsylvania: prevalence and effects on somatic cell count and milk production. J Dairy Sci 1997, 80:2592-2598.
    • (1997) J Dairy Sci , vol.80 , pp. 2592-2598
    • Wilson, D.J.1    Gonzalez, R.N.2    Das, H.H.3
  • 4
    • 0023745576 scopus 로고
    • Etiological agents of bovine mastitis
    • Watts J.L. Etiological agents of bovine mastitis. Vet Microbiol 1988, 16:41-66.
    • (1988) Vet Microbiol , vol.16 , pp. 41-66
    • Watts, J.L.1
  • 5
    • 49449089910 scopus 로고    scopus 로고
    • Staphylococcus aureus antigens and challenges in vaccine development
    • Middleton J.R. Staphylococcus aureus antigens and challenges in vaccine development. Expert Rev Vaccines 2008, 7:805-815.
    • (2008) Expert Rev Vaccines , vol.7 , pp. 805-815
    • Middleton, J.R.1
  • 7
    • 0041386346 scopus 로고    scopus 로고
    • In vivo and in vitro demonstration that Staphylococcus aureus is an intracellular pathogen in the presence or absence of fibronectin-binding proteins
    • Brouillette E., Grondin G., Shkreta L., Lacasse P., Talbot B.G. In vivo and in vitro demonstration that Staphylococcus aureus is an intracellular pathogen in the presence or absence of fibronectin-binding proteins. Microb Pathog 2003, 35:159-168.
    • (2003) Microb Pathog , vol.35 , pp. 159-168
    • Brouillette, E.1    Grondin, G.2    Shkreta, L.3    Lacasse, P.4    Talbot, B.G.5
  • 8
    • 0034559944 scopus 로고    scopus 로고
    • Demonstration of intracellular Staphylococcus aureus in bovine mastitis alveolar cells and macrophages isolated from naturally infected cow milk
    • Hebert A., Sayasith K., Senechal S., Dubreuil P., Lagace J. Demonstration of intracellular Staphylococcus aureus in bovine mastitis alveolar cells and macrophages isolated from naturally infected cow milk. FEMS Microbiol Lett 2000, 193:57-62.
    • (2000) FEMS Microbiol Lett , vol.193 , pp. 57-62
    • Hebert, A.1    Sayasith, K.2    Senechal, S.3    Dubreuil, P.4    Lagace, J.5
  • 10
    • 0024341103 scopus 로고
    • Roles of alpha-toxin and beta-toxin in virulence of Staphylococcus aureus for the mouse mammary gland
    • Bramley A.J., Patel A.H., O'Reilly M., Foster R., Foster T.J. Roles of alpha-toxin and beta-toxin in virulence of Staphylococcus aureus for the mouse mammary gland. Infect Immun 1989, 57:2489-2494.
    • (1989) Infect Immun , vol.57 , pp. 2489-2494
    • Bramley, A.J.1    Patel, A.H.2    O'Reilly, M.3    Foster, R.4    Foster, T.J.5
  • 11
    • 0037157241 scopus 로고    scopus 로고
    • DNA immunization against the clumping factor A (ClfA) of Staphylococcus aureus
    • Brouillette E., Lacasse P., Shkreta L., Belanger J., Grondin G., Diarra M.S., et al. DNA immunization against the clumping factor A (ClfA) of Staphylococcus aureus. Vaccine 2002, 20:2348-2357.
    • (2002) Vaccine , vol.20 , pp. 2348-2357
    • Brouillette, E.1    Lacasse, P.2    Shkreta, L.3    Belanger, J.4    Grondin, G.5    Diarra, M.S.6
  • 12
    • 0036715419 scopus 로고    scopus 로고
    • Staphylococcal vaccines
    • Michie C.A. Staphylococcal vaccines. Trends Immunol 2002, 23:461-463.
    • (2002) Trends Immunol , vol.23 , pp. 461-463
    • Michie, C.A.1
  • 13
    • 0038749403 scopus 로고    scopus 로고
    • Optimization of DNA-based vaccination in cows using green fluorescent protein and protein A as a prelude to immunization against staphylococcal mastitis
    • Carter E.W., Kerr D.E. Optimization of DNA-based vaccination in cows using green fluorescent protein and protein A as a prelude to immunization against staphylococcal mastitis. J Dairy Sci 2003, 86:1177-1186.
    • (2003) J Dairy Sci , vol.86 , pp. 1177-1186
    • Carter, E.W.1    Kerr, D.E.2
  • 14
    • 34249025123 scopus 로고    scopus 로고
    • Characterization of the antibody isotype response in serum and milk of heifers vaccinated with a Staphylococcus aureus bacterin (Lysigin)
    • Luby C.D., Middleton J.R., Ma J., Rinehart C.L., Bucklin S., Kohler C., et al. Characterization of the antibody isotype response in serum and milk of heifers vaccinated with a Staphylococcus aureus bacterin (Lysigin). J Dairy Res 2007, 74:239-246.
    • (2007) J Dairy Res , vol.74 , pp. 239-246
    • Luby, C.D.1    Middleton, J.R.2    Ma, J.3    Rinehart, C.L.4    Bucklin, S.5    Kohler, C.6
  • 15
    • 58149496340 scopus 로고    scopus 로고
    • Efficacy of vaccination against staphylococcal mastitis: a review and new data
    • Middleton J.R., Luby C.D., Adams D.S. Efficacy of vaccination against staphylococcal mastitis: a review and new data. Vet Microbiol 2009, 134:192-198.
    • (2009) Vet Microbiol , vol.134 , pp. 192-198
    • Middleton, J.R.1    Luby, C.D.2    Adams, D.S.3
  • 16
    • 79951575916 scopus 로고    scopus 로고
    • Efficacy of Staphylococcus aureus vaccines for bovine mastitis: a systematic review
    • Pereira U.P., Oliveira D.G., Mesquita L.R., Costa G.M., Pereira L.J. Efficacy of Staphylococcus aureus vaccines for bovine mastitis: a systematic review. Vet Microbiol 2011, 148:117-124.
    • (2011) Vet Microbiol , vol.148 , pp. 117-124
    • Pereira, U.P.1    Oliveira, D.G.2    Mesquita, L.R.3    Costa, G.M.4    Pereira, L.J.5
  • 17
    • 37249035215 scopus 로고    scopus 로고
    • Experimental trial in heifers vaccinated with Staphylococcus aureus avirulent mutant against bovine mastitis
    • Pellegrino M., Giraudo J., Raspanti C., Nagel R., Odierno L., Primo V., et al. Experimental trial in heifers vaccinated with Staphylococcus aureus avirulent mutant against bovine mastitis. Vet Microbiol 2008, 127:186-190.
    • (2008) Vet Microbiol , vol.127 , pp. 186-190
    • Pellegrino, M.1    Giraudo, J.2    Raspanti, C.3    Nagel, R.4    Odierno, L.5    Primo, V.6
  • 18
    • 0025650466 scopus 로고
    • CD40 and IgE: synergism between anti-CD40 monoclonal antibody and interleukin 4 in the induction of IgE synthesis by highly purified human B cells
    • Jabara H.H., Fu S.M., Geha R.S., Vercelli D. CD40 and IgE: synergism between anti-CD40 monoclonal antibody and interleukin 4 in the induction of IgE synthesis by highly purified human B cells. J Exp Med 1990, 172:1861-1864.
    • (1990) J Exp Med , vol.172 , pp. 1861-1864
    • Jabara, H.H.1    Fu, S.M.2    Geha, R.S.3    Vercelli, D.4
  • 19
    • 0026092621 scopus 로고
    • Long-term human B cell lines dependent on interleukin-4 and antibody to CD40
    • Banchereau J., de Paoli P., Valle A., Garcia E., Rousset F. Long-term human B cell lines dependent on interleukin-4 and antibody to CD40. Science 1991, 251:70-72.
    • (1991) Science , vol.251 , pp. 70-72
    • Banchereau, J.1    de Paoli, P.2    Valle, A.3    Garcia, E.4    Rousset, F.5
  • 20
    • 0027323354 scopus 로고
    • CD40 expression by human monocytes: regulation by cytokines and activation of monocytes by the ligand for CD40
    • Alderson M.R., Armitage R.J., Tough T.W., Strockbine L., Fanslow W.C., Spriggs M.K. CD40 expression by human monocytes: regulation by cytokines and activation of monocytes by the ligand for CD40. J Exp Med 1993, 178:669-674.
    • (1993) J Exp Med , vol.178 , pp. 669-674
    • Alderson, M.R.1    Armitage, R.J.2    Tough, T.W.3    Strockbine, L.4    Fanslow, W.C.5    Spriggs, M.K.6
  • 22
    • 0032482337 scopus 로고    scopus 로고
    • A conditioned dendritic cell can be a temporal bridge between a CD4+ T-helper and a T-killer cell
    • Ridge J.P., Di Rosa F., Matzinger P. A conditioned dendritic cell can be a temporal bridge between a CD4+ T-helper and a T-killer cell. Nature 1998, 393:474-478.
    • (1998) Nature , vol.393 , pp. 474-478
    • Ridge, J.P.1    Di Rosa, F.2    Matzinger, P.3
  • 24
  • 25
    • 0032213323 scopus 로고    scopus 로고
    • CD40 ligand/trimer DNA enhances both humoral and cellular immune responses and induces protective immunity to infectious and tumor challenge
    • Gurunathan S., Irvine K.R., Wu C.Y., Cohen J.I., Thomas E., Prussin C., et al. CD40 ligand/trimer DNA enhances both humoral and cellular immune responses and induces protective immunity to infectious and tumor challenge. J Immunol 1998, 161:4563-4571.
    • (1998) J Immunol , vol.161 , pp. 4563-4571
    • Gurunathan, S.1    Irvine, K.R.2    Wu, C.Y.3    Cohen, J.I.4    Thomas, E.5    Prussin, C.6
  • 26
    • 0032984496 scopus 로고    scopus 로고
    • CD40 activation in vivo overcomes peptide-induced peripheral cytotoxic T-lymphocyte tolerance and augments anti-tumor vaccine efficacy
    • Diehl L., den Boer A.T., Schoenberger S.P., van der Voort E.I., Schumacher T.N., Melief C.J., et al. CD40 activation in vivo overcomes peptide-induced peripheral cytotoxic T-lymphocyte tolerance and augments anti-tumor vaccine efficacy. Nat Med 1999, 5:774-779.
    • (1999) Nat Med , vol.5 , pp. 774-779
    • Diehl, L.1    den Boer, A.T.2    Schoenberger, S.P.3    van der Voort, E.I.4    Schumacher, T.N.5    Melief, C.J.6
  • 27
    • 0032896709 scopus 로고    scopus 로고
    • CD40 antibody evokes a cytotoxic T-cell response that eradicates lymphoma and bypasses T-cell help
    • French R.R., Chan H.T., Tutt A.L., Glennie M.J. CD40 antibody evokes a cytotoxic T-cell response that eradicates lymphoma and bypasses T-cell help. Nat Med 1999, 5:548-553.
    • (1999) Nat Med , vol.5 , pp. 548-553
    • French, R.R.1    Chan, H.T.2    Tutt, A.L.3    Glennie, M.J.4
  • 28
    • 0035871713 scopus 로고    scopus 로고
    • CD40 signaling converts a minimally immunogenic antigen into a potent vaccine against the intracellular pathogen Listeria monocytogenes
    • Rolph M.S., Kaufmann S.H. CD40 signaling converts a minimally immunogenic antigen into a potent vaccine against the intracellular pathogen Listeria monocytogenes. J Immunol 2001, 166:5115-5121.
    • (2001) J Immunol , vol.166 , pp. 5115-5121
    • Rolph, M.S.1    Kaufmann, S.H.2
  • 29
    • 0035060828 scopus 로고    scopus 로고
    • Vaccination against the intracellular pathogens Leishmania major and L. amazonensis by directing CD40 ligand to macrophages
    • Chen G., Darrah P.A., Mosser D.M. Vaccination against the intracellular pathogens Leishmania major and L. amazonensis by directing CD40 ligand to macrophages. Infect Immun 2001, 69:3255-3263.
    • (2001) Infect Immun , vol.69 , pp. 3255-3263
    • Chen, G.1    Darrah, P.A.2    Mosser, D.M.3
  • 30
    • 0037117542 scopus 로고    scopus 로고
    • CD40 stimulation leads to effective therapy of CD40(-) tumors through induction of strong systemic cytotoxic T lymphocyte immunity
    • van Mierlo G.J., den Boer A.T., Medema J.P., van der Voort E.I., Fransen M.F., Offringa R., et al. CD40 stimulation leads to effective therapy of CD40(-) tumors through induction of strong systemic cytotoxic T lymphocyte immunity. Proc Natl Acad Sci USA 2002, 99:5561-5566.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 5561-5566
    • van Mierlo, G.J.1    den Boer, A.T.2    Medema, J.P.3    van der Voort, E.I.4    Fransen, M.F.5    Offringa, R.6
  • 31
    • 0037087379 scopus 로고    scopus 로고
    • T cell immunity to lymphoma following treatment with anti-CD40 monoclonal antibody
    • Tutt A.L., O'Brien L., Hussain A., Crowther G.R., French R.R., Glennie M.J. T cell immunity to lymphoma following treatment with anti-CD40 monoclonal antibody. J Immunol 2002, 168:2720-2728.
    • (2002) J Immunol , vol.168 , pp. 2720-2728
    • Tutt, A.L.1    O'Brien, L.2    Hussain, A.3    Crowther, G.R.4    French, R.R.5    Glennie, M.J.6
  • 32
    • 34249863582 scopus 로고    scopus 로고
    • Reduced pathology following infection with transgenic Leishmania major expressing murine CD40 ligand
    • Field A.E., Wagage S., Conrad S.M., Mosser D.M. Reduced pathology following infection with transgenic Leishmania major expressing murine CD40 ligand. Infect Immun 2007, 75:3140-3149.
    • (2007) Infect Immun , vol.75 , pp. 3140-3149
    • Field, A.E.1    Wagage, S.2    Conrad, S.M.3    Mosser, D.M.4
  • 33
    • 77958109234 scopus 로고    scopus 로고
    • Immunogene therapy against colon cancer metastasis using an adenovirus vector expressing CD40 ligand
    • Iida T., Shiba H., Misawa T., Ohashi T., Eto Y., Yanaga K. Immunogene therapy against colon cancer metastasis using an adenovirus vector expressing CD40 ligand. Surgery 2010, 148:925-935.
    • (2010) Surgery , vol.148 , pp. 925-935
    • Iida, T.1    Shiba, H.2    Misawa, T.3    Ohashi, T.4    Eto, Y.5    Yanaga, K.6
  • 34
    • 77955780508 scopus 로고    scopus 로고
    • Optimizing dendritic cell-based immunotherapy in multiple myeloma: intranodal injections of idiotype-pulsed CD40 ligand-matured vaccines led to induction of type-1 and cytotoxic T-cell immune responses in patients
    • Yi Q., Szmania S., Freeman J., Qian J., Rosen N.A., Viswamitra S., et al. Optimizing dendritic cell-based immunotherapy in multiple myeloma: intranodal injections of idiotype-pulsed CD40 ligand-matured vaccines led to induction of type-1 and cytotoxic T-cell immune responses in patients. Br J Haematol 2010, 150:554-564.
    • (2010) Br J Haematol , vol.150 , pp. 554-564
    • Yi, Q.1    Szmania, S.2    Freeman, J.3    Qian, J.4    Rosen, N.A.5    Viswamitra, S.6
  • 35
    • 0028041170 scopus 로고
    • Monoclonal antibodies to murine CD40 define two distinct functional epitopes
    • Heath A.W., Wu W.W., Howard M.C. Monoclonal antibodies to murine CD40 define two distinct functional epitopes. Eur J Immunol 1994, 24:1828-1834.
    • (1994) Eur J Immunol , vol.24 , pp. 1828-1834
    • Heath, A.W.1    Wu, W.W.2    Howard, M.C.3
  • 36
    • 0030982709 scopus 로고    scopus 로고
    • Peptide antigen treatment of naive and virus-immune mice: antigen-specific tolerance versus immunopathology
    • Aichele P., Brduscha-Riem K., Oehen S., Odermatt B., Zinkernagel R.M., Hengartner H., et al. Peptide antigen treatment of naive and virus-immune mice: antigen-specific tolerance versus immunopathology. Immunity 1997, 6:519-529.
    • (1997) Immunity , vol.6 , pp. 519-529
    • Aichele, P.1    Brduscha-Riem, K.2    Oehen, S.3    Odermatt, B.4    Zinkernagel, R.M.5    Hengartner, H.6
  • 37
    • 3142766451 scopus 로고    scopus 로고
    • Mouse mastitis model of infection for antimicrobial compound efficacy studies against intracellular and extracellular forms of Staphylococcus aureus
    • Brouillette E., Grondin G., Lefebvre C., Talbot B.G., Malouin F. Mouse mastitis model of infection for antimicrobial compound efficacy studies against intracellular and extracellular forms of Staphylococcus aureus. Vet Microbiol 2004, 101:253-262.
    • (2004) Vet Microbiol , vol.101 , pp. 253-262
    • Brouillette, E.1    Grondin, G.2    Lefebvre, C.3    Talbot, B.G.4    Malouin, F.5
  • 39
    • 0343938858 scopus 로고    scopus 로고
    • Soluble antigen and CD40 triggering are sufficient to induce primary and memory cytotoxic T cells
    • Lefrancois L., Altman J.D., Williams K., Olson S. Soluble antigen and CD40 triggering are sufficient to induce primary and memory cytotoxic T cells. J Immunol 2000, 164:725-732.
    • (2000) J Immunol , vol.164 , pp. 725-732
    • Lefrancois, L.1    Altman, J.D.2    Williams, K.3    Olson, S.4
  • 40
    • 12144286596 scopus 로고    scopus 로고
    • In vivo targeting of antigens to maturing dendritic cells via the DEC-205 receptor improves T cell vaccination
    • Bonifaz L.C., Bonnyay D.P., Charalambous A., Darguste D.I., Fujii S., Soares H., et al. In vivo targeting of antigens to maturing dendritic cells via the DEC-205 receptor improves T cell vaccination. J Exp Med 2004, 199:815-824.
    • (2004) J Exp Med , vol.199 , pp. 815-824
    • Bonifaz, L.C.1    Bonnyay, D.P.2    Charalambous, A.3    Darguste, D.I.4    Fujii, S.5    Soares, H.6
  • 41
    • 2542476167 scopus 로고    scopus 로고
    • CD40/CD154 interactions at the interface of tolerance and immunity
    • Quezada S.A., Jarvinen L.Z., Lind E.F., Noelle R.J. CD40/CD154 interactions at the interface of tolerance and immunity. Annu Rev Immunol 2004, 22:307-328.
    • (2004) Annu Rev Immunol , vol.22 , pp. 307-328
    • Quezada, S.A.1    Jarvinen, L.Z.2    Lind, E.F.3    Noelle, R.J.4
  • 42
    • 33750693040 scopus 로고    scopus 로고
    • Phytol-based novel adjuvants in vaccine formulation. 2. Assessment of efficacy in the induction of protective immune responses to lethal bacterial infections in mice
    • Lim S.Y., Bauermeister A., Kjonaas R.A., Ghosh S.K. Phytol-based novel adjuvants in vaccine formulation. 2. Assessment of efficacy in the induction of protective immune responses to lethal bacterial infections in mice. J Immune Based Ther Vaccines 2006, 4:5.
    • (2006) J Immune Based Ther Vaccines , vol.4 , pp. 5
    • Lim, S.Y.1    Bauermeister, A.2    Kjonaas, R.A.3    Ghosh, S.K.4
  • 43
    • 1642362512 scopus 로고    scopus 로고
    • Combined TLR and CD40 triggering induces potent CD8+ T cell expansion with variable dependence on type I IFN
    • Ahonen C.L., Doxsee C.L., McGurran S.M., Riter T.R., Wade W.F., Barth R.J., et al. Combined TLR and CD40 triggering induces potent CD8+ T cell expansion with variable dependence on type I IFN. J Exp Med 2004, 199:775-784.
    • (2004) J Exp Med , vol.199 , pp. 775-784
    • Ahonen, C.L.1    Doxsee, C.L.2    McGurran, S.M.3    Riter, T.R.4    Wade, W.F.5    Barth, R.J.6
  • 44
    • 51549121644 scopus 로고    scopus 로고
    • Combined triggering of dendritic cell receptors results in synergistic activation and potent cytotoxic immunity
    • Wells J.W., Cowled C.J., Farzaneh F., Noble A. Combined triggering of dendritic cell receptors results in synergistic activation and potent cytotoxic immunity. J Immunol 2008, 181:3422-3431.
    • (2008) J Immunol , vol.181 , pp. 3422-3431
    • Wells, J.W.1    Cowled, C.J.2    Farzaneh, F.3    Noble, A.4
  • 45
    • 0030831210 scopus 로고    scopus 로고
    • A human homologue of the Drosophila Toll protein signals activation of adaptive immunity
    • Medzhitov R., Preston-Hurlburt P., Janeway C.A. A human homologue of the Drosophila Toll protein signals activation of adaptive immunity. Nature 1997, 388:394-397.
    • (1997) Nature , vol.388 , pp. 394-397
    • Medzhitov, R.1    Preston-Hurlburt, P.2    Janeway, C.A.3
  • 46
    • 0034886143 scopus 로고    scopus 로고
    • Toll-like receptors: critical proteins linking innate and acquired immunity
    • Akira S., Takeda K., Kaisho T. Toll-like receptors: critical proteins linking innate and acquired immunity. Nat Immunol 2001, 2:675-680.
    • (2001) Nat Immunol , vol.2 , pp. 675-680
    • Akira, S.1    Takeda, K.2    Kaisho, T.3
  • 47
    • 56649108016 scopus 로고    scopus 로고
    • Engagement of TLR signaling as adjuvant: towards smarter vaccine and beyond
    • Lahiri A., Das P., Chakravortty D. Engagement of TLR signaling as adjuvant: towards smarter vaccine and beyond. Vaccine 2008, 26:6777-6783.
    • (2008) Vaccine , vol.26 , pp. 6777-6783
    • Lahiri, A.1    Das, P.2    Chakravortty, D.3
  • 48
    • 0034577944 scopus 로고    scopus 로고
    • Toll-like receptor 2-mediated NF-kappa B activation requires a Rac1-dependent pathway
    • Arbibe L., Mira J.P., Teusch N., Kline L., Guha M., Mackman N., et al. Toll-like receptor 2-mediated NF-kappa B activation requires a Rac1-dependent pathway. Nat Immunol 2000, 1:533-540.
    • (2000) Nat Immunol , vol.1 , pp. 533-540
    • Arbibe, L.1    Mira, J.P.2    Teusch, N.3    Kline, L.4    Guha, M.5    Mackman, N.6
  • 49
    • 37449013073 scopus 로고    scopus 로고
    • Bovine TLR2 and TLR4 properly transduce signals from Staphylococcus aureus and E. coli, but S. aureus fails to both activate NF-kappaB in mammary epithelial cells and to quickly induce TNFalpha and interleukin-8 (CXCL8) expression in the udder
    • Yang W., Zerbe H., Petzl W., Brunner R., Günther J., Draing C., et al. Bovine TLR2 and TLR4 properly transduce signals from Staphylococcus aureus and E. coli, but S. aureus fails to both activate NF-kappaB in mammary epithelial cells and to quickly induce TNFalpha and interleukin-8 (CXCL8) expression in the udder. Mol Immunol 2008, 45:1385-1397.
    • (2008) Mol Immunol , vol.45 , pp. 1385-1397
    • Yang, W.1    Zerbe, H.2    Petzl, W.3    Brunner, R.4    Günther, J.5    Draing, C.6
  • 50
    • 18044389499 scopus 로고    scopus 로고
    • The pathogenesis and control of Staphylococcus aureus-induced mastitis: study models in the mouse
    • Brouillette E., Malouin F. The pathogenesis and control of Staphylococcus aureus-induced mastitis: study models in the mouse. Microbes Infect 2005, 7:560-568.
    • (2005) Microbes Infect , vol.7 , pp. 560-568
    • Brouillette, E.1    Malouin, F.2
  • 51
    • 0028196602 scopus 로고
    • Virulence factors involved in the pathogenesis of bovine intramammary infections due to Staphylococcus aureus
    • Sutra L., Poutrel B. Virulence factors involved in the pathogenesis of bovine intramammary infections due to Staphylococcus aureus. J Med Microbiol 1994, 40:79-89.
    • (1994) J Med Microbiol , vol.40 , pp. 79-89
    • Sutra, L.1    Poutrel, B.2


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