An efficient synthesis of 3,3-difluoro-pyrrolidine hydrochloride starting with 2-chloro-2,2-difluoroacetic acid

Journal of Fluorine Chemistry

Volumn 135, Issue , 2012, Pages 354-357

  Wei, Lulin ^a   Makowski, Teresa M ^a   Rutherford, Jennifer L ^b  

^a PFIZER INC   (United States)

^b LAFAYETTE COLLEGE   (United States)

Author keywords

2 Chloro 2,2 difluoroacetic acid; 3,3 Difluoropyrrolidine hydrochloride; Catalytic hydrogenation cyclization; Reductive nitromethylation

Indexed keywords

EID: 84857360969     PISSN: 00221139     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jfluchem.2011.08.009     Document Type: Article

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