Phenotypic and genetic characterization of adult T-cell acute lymphoblastic leukemia with del(9)(q34);SET-NUP214 rearrangement

Annals of Hematology

Volumn 91, Issue 2, 2012, Pages 193-201

  Chae, Hyojin ^a   Lim, Jihyang ^a,b   Kim, Myungshin ^a   Park, Joonhong ^a   Kim, Yonggoo ^a   Han, Kyungja ^a   Lee, Seok ^a   Min, Woo Sung ^a  

^a The Catholic University of Korea   (South Korea)

^b The Catholic University of Korea   (South Korea)

Author keywords

Breakpoint sequencing; del(9)(q34); SET NUP214; T cell ALL

Indexed keywords

CD33 ANTIGEN; MICROSOMAL AMINOPEPTIDASE;

ACUTE LYMPHOBLASTIC LEUKEMIA; ADOLESCENT; ADULT; ARTICLE; CHROMOSOME ABERRATION; CHROMOSOME ANALYSIS; CHROMOSOME BREAKAGE; CHROMOSOME DELETION; CHROMOSOME DELETION 9Q34; CHROMOSOME TRANSLOCATION; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; GENE LOCATION; GENE PRODUCT; GENE REARRANGEMENT; GENE SEQUENCE; GENETIC ANALYSIS; GENETIC MARKER; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOPHENOTYPING; INTRON; MALE; PHENOTYPE; PRE T LYMPHOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SET NUP214 GENE; T LYMPHOCYTE;

ADOLESCENT; ADULT; AGED; ANTIGENS, CD; COMPARATIVE GENOMIC HYBRIDIZATION; CYTOGENETICS; FEMALE; GENE REARRANGEMENT; HISTONE CHAPERONES; HUMANS; IMMUNOPHENOTYPING; IN SITU HYBRIDIZATION, FLUORESCENCE; MALE; MIDDLE AGED; NUCLEAR PORE COMPLEX PROTEINS; PHENOTYPE; PRECURSOR T-CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA; TRANSCRIPTION FACTORS; YOUNG ADULT;

EID: 84857356620     PISSN: 09395555     EISSN: 14320584     Source Type: Journal    
DOI: 10.1007/s00277-011-1289-x     Document Type: Article

References (18)

1. HJ Adriaansen AH Guerts van Kessel JH Wijdenes-de Bresser E van Drunen-Schoenmaker JJ van Dongen 1990 Expression of the myeloid differentiation antigen CD33 depends on the presence of human chromosome 19 in human-mouse hybrids Ann Hum Genet 54 115 119 1696442 10.1111/j.1469-1809.1990.tb00367.x 1:STN:280:DyaK3czktlamsg%3D%3D (Pubitemid 20183486)
2. R Rosati R La Starza G Barba P Gorello V Pierini C Matteucci G Roti B Crescenzi T Aloisi F Aversa MF Martelli C Mecucci 2007 Cryptic chromosome 9q34 deletion generates TAF-1α/CAN and TAF-1β/CAN fusion transcripts in acute myeloid leukemia Hematologica 92 232 235 10.3324/haematol.10538 1:CAS:528:DC%2BD2sXhtFGqurfN
3. P van Vlierberghe M van Grotel J Tchinda C Lee HB Becerloo PJ van der Spek A Stubbs F Cools K Nagata M Fornerod J Buijs-Gladdines M Horstmann ER van Wering J Soulier R Pieters JP Meijerink 2008 The recurrent SET-NUP214 fusion as a new HOXA activation mechanism in pediatric T-cell acute lymphoblastic leukemia Blood 111 4668 4680 18299449 10.1182/blood-2007-09-111872
4. P Gorello R La Starza E Varasano S Chiaretti L Elia V Pierini G Barba L Brandimarte B Crescenzi A Vitale M Messina S Grammatico M Mancini C Matteucci A Bardi A Guarini MF Martelli R Foà C Mecucci 2010 Combined interphase fluorescence in situ hybridization elucidates the genetic heterogeneity of T-cell acute lymphoblastic leukemia in adults Haematologica 95 79 86 20065082 10.3324/haematol.2009.010413 1:CAS:528:DC%2BC3cXitlals70%3D
5. JJ van Dongen AW Langerak M Brüggemann PA Evans M Hummel FL Lavender E Delabesse F Davi E Schuuring R García-Sanz JH van Krieken J Droese D González C Bastard HE White M Spaargaren M González A Parreira JL Smith GJ Morgan M Kneba EA Macintyre 2003 Design and standardization of PCR primers and protocols for detection of clonal immunoglobulin and T-cell receptor gene recombinations in suspect lymphoproliferations: report of the BIOMED-2 Concerted Action BMH4-CT98-3936 Leukemia 17 2257 2317 14671650 10.1038/sj.leu.2403202 (Pubitemid 38072572)
6. H Quentmeier B Schneider S Rohrs J Romani M Zaborski RA Macleod HG Drexler 2009 SET-NUP214 fusion in acute myeloid leukemia- and T-cell acute lymphoblastic leukemia-derived cell lines J Hematol Oncol 2 1 5 10.1186/1756-8722-2-3
7. Rozen S, Skaletsky HJ (2000) Primer 3 on the WWW for general users and for biologist programmers. In: Krawetz S, Mixener S (eds) Bioinformatics methods and protocols: Methods in molecular biology. Humana Press, Totowa, pp 365-386
8. FM Uckun HN Sather PS Gaynon EC Authur ME Trigg DG Tubergen J Nachman PG Steinherz MG Sensel GH Reaman 1997 Clinical features and treatment outcome of children with myeloid antigen positive acute lymphoblastic leukemia: a report from the Children's Cancer Group Blood 90 28 35 9207434 1:CAS:528: DyaK2sXktlaqsbo%3D (Pubitemid 27276543)
9. A Kandilci E Mientjes G Grosveld 2004 Effects of SET and SET-CAN on the differentiation of the human promonocytic cell line U937 Leukemia 18 337 370 14671643 10.1038/sj.leu.2403227 1:CAS:528:DC%2BD2cXlt1agtw%3D%3D (Pubitemid 38240051)
10. S Saito K Nouno R Shimizu M Yamamoto K Nagata 2007 Impairment of erythroid and megakaryocytic differentiation by a leukemia-associated and t(9;9)-derived fusion gene product, SET/TAF1b-CAN/NUP214 J Cell Physiol 214 322 333 10.1002/jcp.21199 (Pubitemid 350308988)
11. J Kim SG Lee J Song SJ Kim SY Rha KA Lee TS Park JR Choi 2010 Molecular characterization of alternative SET-NUP214 fusion transcripts in a case of acute undifferentiated leukemia Cancer Genet Cytogenet 201 73 80 20682390 10.1016/j.cancergencyto.2010.05.010 1:CAS:528:DC%2BC3cXpsFOqtrk%3D
12. HJ Adriaansen PW Soeting IL Wolvers-Tettero JJ van Dongen 1991 Immunoglobulin and T-cell receptor gene rearrangements in acute non-lymphocytic leukemias. Analysis of 54 cases and a review of the literature Leukemia 5 744 751 1943227 1:STN:280:DyaK38%2FkslGqtQ%3D%3D
13. D Caudell PD Aplan 2008 The role of CALM-AF10 gene fusion in acute leukemia Leukemia 22 678 685 18094714 10.1038/sj.leu.2405074 1:CAS:528:DC%2BD1cXks12rt7k%3D (Pubitemid 351552620)
14. M von Lindern D Breems S van Baals H Adriaansen G Grosveld 1992 Characterization of the translocation breakpoint sequences of two DEK-CAN fusion genes present in t(6;9) acute myeloid leukemia and a SET-CAN fusion gene found in a case of acute undifferentiated leukemia Genes Chromosomes Cancer 5 227 234 10.1002/gcc.2870050309
15. K De Keersmaecker P Marynen J Cools 2005 Genetic insights in the pathogenesis of T-cell acute lymphoblastic leukemia Haematologica 90 1116 1127 16079112 (Pubitemid 41323512)
16. U Ozbek A Kandilci S van Baal J Bonten K Boyd P Franken R Fodde GC Fosveld 2007 SET-CAN, the product of the t(9;9) in acute undifferentiated leukemia, causes expansion of early hematopoietic progenitors and hyperproliferation of stomach mucosa in transgenic mice Am J Pathol 17 654 666 10.2353/ajpath.2007.060934 (Pubitemid 47344697)
17. P Andreasson B Johansson K Arheden R Billström F Mitelman M Hoglund 1997 Deletions of CDKN1B and ETV6 in acute myeloid leukemia and myelodysplastic syndromes without cytogenetic evidence of 12p abnormalities Genes Chromosomes Cancer 19 77 83 9171997 10.1002/(SICI)1098-2264(199706)19:2<77::AID- GCC2>3.0.CO;2-X 1:CAS:528:DyaK2sXjvVOku74%3D (Pubitemid 27231481)
18. S Hayette X Thomas Y Bertrand I Tigaud M Callanan A Thiebaut C Charrin E Archimbaud JP Magaud R Rimokh 1997 Molecular analysis of cyclin-dependent kinase inhibitors in human leukemias Leukemia 11 1696 1699 9324291 10.1038/sj.leu.2400814 1:CAS:528:DyaK2sXnsV2hsro%3D (Pubitemid 27458609)