Roles of mechanical force and CXCR1/CXCR2 in shear-stress-induced endothelial cell migration

European Biophysics Journal

Volumn 41, Issue 1, 2012, Pages 13-25

  Zeng, Ye ^a,b   Shen, Yang ^a,b   Huang, Xian Liang ^a,b   Liu, Xiao Jing ^a   Liu, Xiao Heng ^a,b  

^a SICHUAN UNIVERSITY   (China)

^b SICHUAN UNIVERSITY   (China)

Author keywords

Angiogenesis; Hemodynamic force; HUVEC; Mechanosensor; Synergistic effect; Wound progress

Indexed keywords

CHEMOKINE RECEPTOR CXCR1; CHEMOKINE RECEPTOR CXCR2;

ARTICLE; BIOMECHANICS; CELL MOTION; CYTOLOGY; HUMAN; MECHANICAL STRESS; METABOLISM; UMBILICAL VEIN ENDOTHELIAL CELL;

BIOMECHANICS; CELL MOVEMENT; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; RECEPTORS, INTERLEUKIN-8A; RECEPTORS, INTERLEUKIN-8B; STRESS, MECHANICAL;

EID: 84857356495     PISSN: 01757571     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00249-011-0752-x     Document Type: Article

References (47)

1. Addison CL, Daniel TO, Burdick MD, Liu H, Ehlert JE, Xue YY, Buechi L, Walz A, Richmond A, Strieter RM (2000) The CXC chemokine receptor 2, CXCR2, is the putative receptor for ELR + CXC chemokine-induced angiogenic activity. J Immunol 165:5269-5277
2. Albuquerque ML, Waters CM, Savla U, Schnaper HW, Flozak AS (2000) Shear stress enhances human endothelial cell wound closure in vitro. Am J Physiol Heart Circ Physiol 279:H293-H302 (Pubitemid 30616673)
3. Barakat A, Lieu D (2003) Differential responsiveness of vascular endothelial cells to different types of fluid mechanical shear stress. Cell Biochem Biophys 38:323-343 (Pubitemid 41270812)
4. Cai G, Lian J, Shapiro SS, Beacham DA (2000) Evaluation of endothelial cell migration with a novel in vitro assay system. Methods Cell Sci 22:107-114 (Pubitemid 32218761)
5. Chen CS, Mrksich M, Huang S, Whitesides GM, Ingber DE (1997) Geometric control of cell life and death. Science 276:1425-1428 (Pubitemid 27235413)
6. Cheng C, Tempel D, van Haperen R, van der Baan A, Grosveld F, Daemen MJ, Krams R, de Crom R (2006) Atherosclerotic lesion size and vulnerability are determined by patterns of fluid shear stress. Circulation 113:2744-2753 (Pubitemid 43947992)
7. Cheng M, Liu X, Li Y, Tang R, Zhang W, Wu J, Li L, Gang Y, Chen H (2007a) IL-8 gene induction by low shear stress: pharmacological evaluation of the role of signaling molecules. Biorheology 44:349-360
8. Cheng M, Wu J, Liu X, Li Y, Nie Y, Li L, Chen H (2007b) Low shear stress-induced interleukin-8 mRNA expression in endothelial cells is mechanotransduced by integrins and the cytoskeleton. Endothelium 14:265-273
9. Chien S (2007) Mechanotransduction and endothelial cell homeostasis: the wisdom of the cell. Am J Physiol Heart Circ Physiol 292:H1209-H1224 (Pubitemid 46377111)
10. Chien S (2008) Role of shear stress direction in endothelial mechanotransduction. Mol Cell Biomech 5:1-8 (Pubitemid 351791112)
11. Chien S, Li S, Shyy YJ (1998) Effects of mechanical forces on signal transduction and gene expression in endothelial cells. Hypertension 31:162-169
12. Chiu JJ, Usami S, Chien S (2009) Vascular endothelial responses to altered shear stress: pathologic implications for atherosclerosis. Ann Med 41:19-28
13. Chung CY, Funamoto S, Firtel RA (2001) Signaling pathways controlling cell polarity and chemotaxis. Trends Biochem Sci 26:557-566 (Pubitemid 32823441)
14. Chuntharapai A, Kim KJ (1995) Regulation of the expression of IL-8 receptor A/B by IL-8: possible functions of each receptor. J Immunol 155:2587-2594
15. Davies PF (1995) Flow-mediated endothelial mechanotransduction. Physiol Rev 75:519-560
16. del Álamo JC, Norwich GN, Y-SJ Li, Lasheras JC, Chien S (2008) Anisotropic rheology and directional mechanotransduction in vascular endothelial cells. Proc Natl Acad Sci USA 105:15411-15416
17. Fan WH, Pech M, Karnovsky MJ (2000) Connective tissue growth factor (CTGF) stimulates vascular smooth muscle cell growth and migration in vitro. Eur J Cell Biol 79:915-923 (Pubitemid 32000725)
18. Feil C, Augustin HG (1998) Endothelial cells differentially express functional CXC-chemokine receptor-4 (CXCR-4/fusin) under the control of autocrine activity and exogenous cytokines. Biochem Biophys Res Commun 247:38-45 (Pubitemid 28412521)
19. Gojova A, Barakat AI (2005) Vascular endothelial wound closure under shear stress: role of membrane fluidity and flow-sensitive ion channels. J Appl Physiol 98:2355-2362 (Pubitemid 40726937)
20. Hsu S, Thakar R, Liepmann D, Li S (2005) Effects of shear stress on endothelial cell haptotaxis on micropatterned surfaces. Biochem Biophys Res Commun 337:401-409 (Pubitemid 41393809)
21. Janetopoulos C, Firtel RA (2008) Directional sensing during chemotaxis. FEBS Lett 582:2075-2085
22. Kolsch V, Charest PG, Firtel RA (2008) The regulation of cell motility and chemotaxis by phospholipid signaling. J Cell Sci 121:551-559 (Pubitemid 351524153)
23. Lamalice L, Le Boeuf F, Huot J (2007) Endothelial cell migration during angiogenesis. Circ Res 100:782-794 (Pubitemid 46555683)
24. Lauffenburger DA, Horwitz AF (1996) Cell migration: a physically integrated molecular process. Cell 84:359-369 (Pubitemid 26058561)
25. Levesque MJ, Nerem RM (1985) The elongation and orientation of cultured endothelial cells in response to shear stress. J Biomech Eng 107:341-347
26. Li S, Huang NF, Hsu S (2005) Mechanotransduction in endothelial cell migration. J Cell Biochem 96:1110-1126 (Pubitemid 41681854)
27. Liu SQ, Yen M, Fung YC (1994) On measuring the third dimension of cultured endothelial cells in shear flow. Proc Natl Acad Sci USA 91:8782-8786
28. Liu X, Luo F, Pan K, Wu W, Chen H (2007) High glucose upregulates connective tissue growth factor expression in human vascular smooth muscle cells. BMC Cell Biol 8:1
29. Lyons L (1991) A practical guide to data analysis for physical science students. Cambridge University Press, New York
30. Melchior B, Frangos JA (2010) Shear-induced endothelial cell-cell junction inclination. Am J Physiol Cell Physiol 299:C621-C629
31. Mestas J, Burdick MD, Reckamp K, Pantuck A, Figlin RA, Strieter RM (2005) The role of CXCR2/CXCR2 ligand biological axis in renal cell carcinoma. J Immunol 175:5351-5357 (Pubitemid 41456421)
32. Mofrad RKM, Kamm DR (2006) Cytoskeletal mechanics: models and measurements. Cambridge University Press, New York
33. Murdoch C, Monk PN, Finn A (1999) Cxc chemokine receptor expression on human endothelial cells. Cytokine 11:704-712 (Pubitemid 29428004)
34. Petrie RJ, Doyle AD, Yamada KM (2009) Random versus directionally persistent cell migration. Nat Rev Mol Cell Biol 10:538-549
35. ResnickN,Yahav H, Shay-Salit A, Shushy M, Schubert S, Zilberman LC, Wofovitz E (2003) Fluid shear stress and the vascular endothelium: for better and for worse. Prog Biophys Mol Biol 81:177-199 (Pubitemid 36551198)
36. Salcedo R, Resau JH, Halverson D, Hudson EA, Dambach M, Powell D, Wasserman K, Oppenheim JJ (2000) Differential expression and responsiveness of chemokine receptors (CXCR1-3) by human microvascular endothelial cells and umbilical vein endothelial cells. FASEB J 14:2055-2064
37. Savla U, Waters CM (1998) Mechanical strain inhibits repair of airway epithelium in vitro. Am J Physiol 274:L883-L892
38. Schraufstatter IU, Chung J, Burger M (2001) IL-8 activates endothelial cell CXCR1 and CXCR2 through Rho and Rac signaling pathways. Am J Physiol Lung Cell Mol Physiol 280:L1094-L1103
39. Schraufstatter IU, Trieu K, Zhao M, Rose DM, Terkeltaub RA, Burger M (2003) IL-8-mediated cell migration in endothelial cells depends on cathepsin B activity and transactivation of the epidermal growth factor receptor. J Immunol 171:6714-6722 (Pubitemid 37532104)
40. Sheetz MP, Felsenfeld D, Galbraith CG, Choquet D (1999) Cell migration as a five-step cycle. Biochem Soc Symp 65:233-243 (Pubitemid 129541623)
41. Singh S, Sadanandam A, Varney ML, Nannuru KC, Singh RK (2010) Small interfering RNA-mediated CXCR1 or CXCR2 knockdown inhibits melanoma tumor growth and invasion. Int J Cancer 126:328-336
42. Stroka KM, Aranda-Espinoza H (2010) A biophysical view of the interplay between mechanical forces and signaling pathways during transendothelial cell migration. FEBS J 277:1145-1158
43. Urbich C, Dernbach E, Reissner A, Vasa M, Zeiher AM, Dimmeler S (2002) Shear stress-induced endothelial cell migration involves integrin signaling via the fibronectin receptor subunits alpha(5) and beta(1). Arterioscler Thromb Vasc Biol 22:69-75 (Pubitemid 34076234)
44. Uttayarat P, Chen M, Li M, Allen FD, Composto RJ, Lelkes PI (2008) Microtopography and flow modulate the direction of endothelial cell migration. Am J Physiol Heart Circ Physiol 294:H1027-H1035 (Pubitemid 351253317)
45. Van Haastert PJ, Devreotes PN (2004) Chemotaxis: signalling the way forward. Nat Rev Mol Cell Biol 5:626-634 (Pubitemid 39025063)
46. Zeng Y, Sun HR, Yu C, Lai Y, Liu XJ, Wu J, Chen HQ, Liu XH (2011a) CXCR1 and CXCR2 are novel mechano-sensors mediating laminar shear stress-induced endothelial cell migration. Cytokine 53:42-51
47. Zeng Y, Liu XH, Shen Y, Lai Y, Liu XJ (2011b) Laminar shear stress promotes endothelial cell migration and inhibits cell apoptosis in the presence of hydroxyurea. Cell Mol Biol (Noisyle-grand) 57 (Suppl):OL1550-OL1557