-
1
-
-
33847381100
-
-
Hajduk, PJ, Greer, J. Nat. Rev. Drug Discov., 2007, 6, 211.
-
(2007)
Nat. Rev. Drug Discov.
, vol.6
, pp. 211
-
-
Hajduk, P.J.1
Greer, J.2
-
2
-
-
79952429629
-
-
Hubbard, RE, Murray, JB. Methods in Enzymology, 2011, 493, 509-531.
-
(2011)
Methods in Enzymology
, vol.493
, pp. 509-531
-
-
Hubbard, R.E.1
Murray, J.B.2
-
3
-
-
67649341990
-
-
Chessari, G, Woodhead, AJ. Drug Discov. Today, 2009, 14, 668-675.
-
(2009)
Drug Discov. Today
, vol.14
, pp. 668-675
-
-
Chessari, G.1
Woodhead, A.J.2
-
4
-
-
46849089254
-
-
Congreve, M, Chessari, G, Tisi, D, Woodhead, AJ. J. Med. Chem., 2008, 51, 3661-3680.
-
(2008)
J. Med. Chem.
, vol.51
, pp. 3661-3680
-
-
Congreve, M.1
Chessari, G.2
Tisi, D.3
Woodhead, A.J.4
-
5
-
-
0031024171
-
-
Lipinski, CA, Lombardo, F, Dominy, DW, Feeney, PJ. Adv. Drug Deliv. Rev., 1997, 23 3-25.
-
(1997)
Adv. Drug Deliv. Rev.
, vol.23
, pp. 3-25
-
-
Lipinski, C.A.1
Lombardo, F.2
Dominy, D.W.3
Feeney, P.J.4
-
6
-
-
0035289779
-
-
Lipinski, CA, Lombardo, F, Dominy, DW, Feeney, PJ. Adv. Drug Deliv. Rev., 2001, 46 3-26.
-
(2001)
Adv. Drug Deliv. Rev.
, vol.46
, pp. 3-26
-
-
Lipinski, C.A.1
Lombardo, F.2
Dominy, D.W.3
Feeney, P.J.4
-
7
-
-
0035324944
-
-
Hann, MM, Leach, AR, Harper, GJ. Chem. Inf. Comput. Sci.; 2001, 41, 856-864.
-
(2001)
Chem. Inf. Comput. Sci.
, vol.41
, pp. 856-864
-
-
Hann, M.M.1
Leach, A.R.2
Harper, G.J.3
-
10
-
-
67650999672
-
-
Chen, IJ, Hubbard, RE. J. Comput. Aid. Mol. Des., 2009, 23, 603-620.
-
(2009)
J. Comput. Aid. Mol. Des.
, vol.23
, pp. 603-620
-
-
Chen, I.J.1
Hubbard, R.E.2
-
12
-
-
36248956723
-
-
Hubbard, RE, Davis, B, Chen, I, Drysdale, M. J. Curr. Top. Med. Chem., 2007, 7 1568.
-
(2007)
J. Curr. Top. Med. Chem.
, vol.7
, pp. 1568
-
-
Hubbard, R.E.1
Davis, B.2
Chen, I.3
Drysdale, M.4
-
13
-
-
84857349899
-
-
DOI 10.1007/s10822-009-964-5
-
Blomberg, N, Cosgrove, DA, Kenny, PW, Kolmodin, K. J. Comput. Aided Des., DOI 10.1007/s10822-009-964-5.
-
J. Comput. Aided Des.
-
-
Blomberg, N.1
Cosgrove, D.A.2
Kenny, P.W.3
Kolmodin, K.4
-
14
-
-
0141726877
-
-
Congreve, M, Carr, R, Murray, C, Jhoti, H. Drug Dis. Today, 2003, 8, 876-877.
-
(2003)
Drug Dis. Today
, vol.8
, pp. 876-877
-
-
Congreve, M.1
Carr, R.2
Murray, C.3
Jhoti, H.4
-
16
-
-
0035044857
-
-
English, AC, Groom, CR, Hubbard, RE. Protein Eng., 2001, 14, 47-59.
-
(2001)
Protein Eng.
, vol.14
, pp. 47-59
-
-
English, A.C.1
Groom, C.R.2
Hubbard, R.E.3
-
18
-
-
40849125892
-
-
Leach, AR, Hann, MM, Burrows, JN, Griffen, EJ. Mol. BioSyst., 2006, 2, 429-446.
-
(2006)
Mol. BioSyst.
, vol.2
, pp. 429-446
-
-
Leach, A.R.1
Hann, M.M.2
Burrows, J.N.3
Griffen, E.J.4
-
19
-
-
0038173393
-
-
Butina, D, Gola, JMR. Chem. Inf. Comput Sci., 2003, 43, 837-841.
-
(2003)
Chem. Inf. Comput Sci.
, vol.43
, pp. 837-841
-
-
Butina, D.1
Gola, J.M.R.2
-
20
-
-
11144354973
-
-
Baurin, N, Baker, R, Richardson, C, Chen, I, Foloppe, N, Potter, A, Jorden, A, Roughley, S, Parratt M, Greaney, P, Morley, D, Hubbard, R. J. Chem. Inf. Comput. Sci., 2004, 44, 643-651.
-
(2004)
J. Chem. Inf. Comput. Sci.
, vol.44
, pp. 643-651
-
-
Baurin, N.1
Baker, R.2
Richardson, C.3
Chen, I.4
Foloppe, N.5
Potter, A.6
Jorden, A.7
Roughley, S.8
Parratt, M.9
Greaney, P.10
Morley, D.11
Hubbard, R.12
-
21
-
-
0035526162
-
-
Tetko, IV, Tanchuk, VY, Kasheva, TN, Viaal, AEP. J. Chem. Inf. Comput. Sci., 2001, 41, 1488-1493.
-
(2001)
J. Chem. Inf. Comput. Sci.
, vol.41
, pp. 1488-1493
-
-
Tetko, I.V.1
Tanchuk, V.Y.2
Kasheva, T.N.3
Viaal, A.E.P.4
-
22
-
-
10044246303
-
-
Baurin, N, Aboul-Ela, F, Barril, X, Davis, B, Drysdale, M, Dymock, B, Finch, H, Fromont, C, Richardson, C, Simmonite, H, Hubbard, R. J. Chem. Inf. Comput Sci., 2004, 44, 2157-2166.
-
(2004)
J. Chem. Inf. Comput Sci.
, vol.44
, pp. 2157-2166
-
-
Baurin, N.1
Aboul-Ela, F.2
Barril, X.3
Davis, B.4
Drysdale, M.5
Dymock, B.6
Finch, H.7
Fromont, C.8
Richardson, C.9
Simmonite, H.10
Hubbard, R.11
-
23
-
-
57549115967
-
-
Gianti, E, Sartori, L. J. Chem. Inform. Mod., 2008, 48, 2129-2139.
-
(2008)
J. Chem. Inform. Mod.
, vol.48
, pp. 2129-2139
-
-
Gianti, E.1
Sartori, L.2
-
24
-
-
36549033318
-
-
Siegal, G, AB, E, Schultz, J. Drug Dis. Today, 2007, 12, 1032-1039.
-
(2007)
Drug Dis. Today
, vol.12
, pp. 1032-1039
-
-
Siegal, G.1
Ab, E.2
Schultz, J.3
-
25
-
-
61649114657
-
-
Akritopoulou-Zanze, I, Hajduk, PJ. Drug Discov. Today, 2009, 14, 291-297.
-
(2009)
Drug Discov. Today
, vol.14
, pp. 291-297
-
-
Akritopoulou-Zanze, I.1
Hajduk, P.J.2
-
26
-
-
34247194965
-
-
Fink, T, Reymond, JL. J. Chem. Inf. Model., 2007, 47, 342-353.
-
(2007)
J. Chem. Inf. Model.
, vol.47
, pp. 342-353
-
-
Fink, T.1
Reymond, J.L.2
-
29
-
-
36248956723
-
-
Hubbard, RE, Davis, B, Chen, I, Drysdale, MJ. Curr. Top. Med. Chem., 2007, 7, 1568.
-
(2007)
Curr. Top. Med. Chem.
, vol.7
, pp. 1568
-
-
Hubbard, R.E.1
Davis, B.2
Chen, I.3
Drysdale, M.J.4
-
30
-
-
79952430797
-
-
Tounge, BA, Parker, MH. Meth. in Enzym., 2011, 493, 3-20.
-
(2011)
Meth. in Enzym.
, vol.493
, pp. 3-20
-
-
Tounge, B.A.1
Parker, M.H.2
-
31
-
-
84857324555
-
-
Shemetulskis, NE, Weininger, D, Blankley, CJ, Yang, JJ, Humblet, C. J. Chem. Inf. Comput. Sci., 1996, 36, 826-871.
-
(1996)
J. Chem. Inf. Comput. Sci.
, vol.36
, pp. 826-871
-
-
Shemetulskis, N.E.1
Weininger, D.2
Blankley, C.J.3
Yang, J.J.4
Humblet, C.5
-
32
-
-
77952772341
-
-
Rogers, D, Hahn, M. J. Chem Inf. Model, 2010, 50, 742-754.
-
(2010)
J. Chem Inf. Model
, vol.50
, pp. 742-754
-
-
Rogers, D.1
Hahn, M.2
-
34
-
-
39349111616
-
-
Stoichet, BK et al. J. Med. Chem., 2002, 45, 8, 1712-1722.
-
(2002)
J. Med. Chem.
, vol.45
, Issue.8
, pp. 1712-1722
-
-
Stoichet, B.K.1
-
35
-
-
84857242523
-
-
poster available at
-
Roeschlaub, CA, Redwood, CJ, Cross, DJ, Bridge, E, Green, S, Overfield, D, Evans, D. High-throughput technique for rapid measurement of fragment solubility, poster available at www.maybridge.com.
-
High-throughput Technique for Rapid Measurement of Fragment Solubility
-
-
Roeschlaub, C.A.1
Redwood, C.J.2
Cross, D.J.3
Bridge, E.4
Green, S.5
Overfield, D.6
Evans, D.7
-
36
-
-
79952382815
-
-
Congreve, M, Rich, RL, Myszka, DG, Siegal, G, Marshall, F. Methods Enzymol., 2011, 493, 115-136.
-
(2011)
Methods Enzymol.
, vol.493
, pp. 115-136
-
-
Congreve, M.1
Rich, R.L.2
Myszka, D.G.3
Siegal, G.4
Marshall, F.5
-
37
-
-
77953082292
-
-
Rich, RL, Myszka, DG. Anal. Biochem., 2010, 402, 170-178.
-
(2010)
Anal. Biochem.
, vol.402
, pp. 170-178
-
-
Rich, R.L.1
Myszka, D.G.2
-
38
-
-
33845902552
-
-
Rich, RL, Myszka, DG. Anal. Biochem., 2007, 361, 1-6.
-
(2007)
Anal. Biochem.
, vol.361
, pp. 1-6
-
-
Rich, R.L.1
Myszka, D.G.2
-
39
-
-
77957234382
-
-
Rich, RL, Quinn, JG, Morton, T, Stepp, JD, Myszka, DG. Anal. Biochem. 2010, 407, 270-277.
-
(2010)
Anal. Biochem.
, vol.407
, pp. 270-277
-
-
Rich, R.L.1
Quinn, J.G.2
Morton, T.3
Stepp, J.D.4
Myszka, D.G.5
|