Low-dose dietary resveratrol has differential effects on colorectal tumorigenesis in adiponectin knockout and wild-type mice

Nutrition and Cancer

Volumn 63, Issue 8, 2011, Pages 1328-1338

  Boddicker, Rebecca L ^a   Whitley, Elizabeth M ^a   Davis, Jeremy E ^b   Birt, Diane F ^a   Spurlock, Michael E ^a  

^a IOWA STATE UNIVERSITY   (United States)

^b SOUTHERN ILLINOIS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADIPONECTIN; AZOXYMETHANE; DEXTRAN SULFATE; GLUCOSE; INSULIN; INTERLEUKIN 6; RESVERATROL;

ADIPOCYTE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY COMPOSITION; BODY MASS; CARCINOGENESIS; CELL PROLIFERATION; COLORECTAL TUMOR; CONCENTRATION (PARAMETERS); DIET; FEMALE; GLUCOSE BLOOD LEVEL; HISTOPATHOLOGY; HUMAN; HUMAN CELL; INFLAMMATION; LIPID DIET; MALE; MOUSE; NONHUMAN; SEX DIFFERENCE; STROMA CELL; WEIGHT GAIN;

ADIPOCYTES; ADIPONECTIN; ANIMALS; AZOXYMETHANE; CACO-2 CELLS; CELL TRANSFORMATION, NEOPLASTIC; COLORECTAL NEOPLASMS; DEXTRAN SULFATE; DIETARY FATS; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HUMANS; INSULIN; INTERLEUKIN-6; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; SEX FACTORS; STILBENES; WEIGHT GAIN;

EID: 84857247491     PISSN: 01635581     EISSN: 15327914     Source Type: Journal    
DOI: 10.1080/01635581.2011.607538     Document Type: Article

References (28)

1. Kang HW, Kim D, Kim HJ, Kim CH, Kim YS, et al. visceral obesity and insulin resistance as risk factors for colorectal adenoma: a cross-sectional, case-control study. Am J Gastroenterol 105, 178-187, 2010.
2. Otake S, Takeda H, Suzuki Y, Fukui T, Watanabe S, et al. Association of visceral fat accumulation and plasma adiponectin with colorectal adenoma: evidence for participation of insulin resistance. Clin Cancer Res 11, 3642-3646, 2005. (Pubitemid 40685579)
3. Birmingham JM, Busik J., Hansen-Smith FM, and Fenton JI: No.elmechanism for obesity-induced colon cancer progression. Carcinogenesis 30, 690-697, 2009.
4. Fenton JI and Birmingham JM: Adipokine regulation of colon cancer: adiponectin attenuates interleukin-6-induced colon carcinoma cell proliferation via STAT-3. Mol Carcinog 49, 700-709, 2010.
5. Schnabele K, Roser S, Rechkemmer G, Hauner H, and Skurk T: Effects of adipocyte-secreted factors on cell cycle progression in HT29 cells. Eur J Nutr 48, 154-161, 2009.
6. Amemori S, Ootani A, Aoki S, Fujise T, Shimoda R, et al. Adipocytes and preadipocytes promote the proliferation of colon cancer cells in vitro. Am J Physiol Gastrointest liver Physiol 292, G923-G929, 2007.
7. Kim AY, Lee YS, Kim KH, Lee JH, Lee HK, et al. Adiponectin represses colon cancer cell proliferation via AdipoR1- and -R2-mediated AMPK activation. Mol Endocrinol 24, 1441-1452, 2010.
8. Sánchez-Fidalgo S, Cárdeno A, villegas I, Talero E, and de la Lastra CA: Dietary supplementation of resveratrol attenuates chronic colonic inflammation in mice. EurJ Pharmacol 633, 78-84, 2010.
9. Cui X, Jin Y, Hofseth AB, Pena E, Habiger J, et al. Resveratrol suppresses colitis and colon cancer associated with colitis. Cancer Pre. Res 3, 549-559, 2010.
10. Youn J, Lee JS, Na HK, Kundu JK, and Surh YJ: Resveratrol and piceatannol inhibit iNOS expression and NF-kappaB activation in dextran sulfate sodium-induced mouse colitis. Nutr Cancer 61, 847-854, 2009.
11. Larrosa M, Yanìfeìz-Gascoìn MaJ, Selma Ma., Gonzaìlez-Sarriìas A, Toti S, et al. Effect of a low dose of dietary resveratrol on colon microbiota, inflammation and tissue damage in a DSS-induced colitis ratmodel. J Agric Food Chem 57, 2211-2220, 2009.
12. Yusuf N, Nasti TH, Meleth S, and Elmets CA: Resveratrol enhances cellmediated immune response to DMBA through TLR4 and prevents DMBA induced cutaneous carcinogenesis. Mol Carcinog 48, 713-723, 2009.
13. Zykova TA, Zhu F, Zhai X, Ma W-Y, Ermakova SP, et al. Resveratrol directly targets COX-2 to inhibit carcinogenesis. Mol Carcinog 47, 797-805, 2008.
14. .anamala J, Reddi.ari L, Radhakrishnan S, and Tar.er C: Resveratrol suppresses IGF-1 induced human colon cancer cell proliferation and ele.ates apoptosis via suppression of IGF-1R/Wnt and activation of p53 signaling pathways. BMC Cancer 10, 238, 2010.
15. Baur JA, Pearson KJ, Price NL, Jamieson HA, Lerin C, et al. Resveratrol improves health and survival of mice on a high-calorie diet. Nature 444, 337-342, 2006. (Pubitemid 44764104)
16. Kang L, Heng W, Yuan A, Baolin L, and Fang H: Resveratrol modulates adipokine expression and impro.es insulin sensitivity in adipocytes: relative to inhibition of inflammatory responsesv Biochimie 92, 789-796, 2010.
17. Rayalam S, Yang J-Y, Ambati S, Della-Fera MA, and Baile CA: Resveratrol induces apoptosis and inhibits adipogenesis in 3T3-L1 adipocytesv Phytotherapy Res 22, 1367-1371, 2008.
18. Picard F, Kurte. M, Chung N, Topark-Ngarm A, Senawong T, et al. Sirt1 promotes fat mobilization in white adipocytes by repressing PPAR- [gamma]. Nature 429, 771-776, 2004. (Pubitemid 38833129)
19. Costa CD, Rohden F, Hammes TO, Margis R, Bortolotto JW, et al. Resveratrol upregulated SIRT1, FOXO1, and adiponectin and downregulated PPARgamma1-3 mRNA expression in human visceral adipocytesv Obes Surg 21, 356-361, 2010.
20. Wang A, Liu M, Liu X, Dong LQ, Glickman RD, et al. Upregulation of adiponectin by resveratrol: the essential roles of the Akt/FOXO1 and AMPK signaling pathways and DsbA-L. J Biol Chem 286, 60-66, 2010.
21. Kineman BD, Au A, Pai.a NL, Kaiser MS, Brummer EC, et al. Transgenic alfalfa that accumulates piceid (trans-resveratrol-3-O-beta-Dglucopyranoside) requires the presence of beta-glucosidase to inhibit the formation of aberrant crypt foci in the colon of CF-1 mice. Nutr Cancer 58, 66-74, 2007. (Pubitemid 47076164)
22. Boddicker RL, Whitley EM, Birt DF, and Spurlock ME: Early lesion formation in colorectal carcinogenesis is associated with adiponectin status whereas neoplastic lesions are associated with diet and sex in C57BL/6J mice. Nutr Cancer (in press).
23. Di Gregorio C, Losi L, Fante R, Modica S, Ghidoni M, et al. Histology of aberrant crypt foci in the human colon. Histopathology 30, 328-334, 1997. (Pubitemid 27168792)
24. Shpitz B, Bomstein Y, Mekori Y, Cohen R, Kaufman Z, et al. Aberrant crypt foci in human colons: distribution and histomorphologic characteristics. Hum Pathol 29, 469-475, 1998. (Pubitemid 28213466)
25. Davis JE, Braucher DR, Walker-Daniels J, and Spurlock ME: Absence of Tlr2 protects against high-fat diet-induced inflammation and results in greater insulin-stimulated glucose transport in cultured adipocytesv J Nutr Biochem 22, 136-141, 2011.
26. Rondini EA, Har.ey AE, Steibel JP, Hursting SD, and Fenton JI: Energy balance modulates colon tumor growth: interactive roles of insulin and estrogen. Mol Carcinog 50, 370-382, 2011.
27. Yakar S, Nunez NP, Pennisi P, Brodt P, Sun H, et al. Increased tumor growth in mice with diet-induced obesity: impact of ovarian hormonesv Endocrinology 147, 5826-5834, 2006. (Pubitemid 44833499)
28. Fischer-Poso.szky P, Kukulus ., Tews D, Unterkircher T, Debatin KM, et al. Resveratrol regulates human adipocyte number and function in a Sirt1-dependent manner. Am J Clin Nutr 92, 5-15, 2010.