Aberrant crypt foci in human colons: Distribution and histomorphologic characteristics

Human Pathology

Volumn 29, Issue 5, 1998, Pages 469-475

  Shpitz, Baruch ^a   Bomstein, Yonit ^a   Mekori, Yosi ^a   Cohen, Razia ^a   Kaufman, Zvi ^a   Neufeld, David ^a   Galkin, Mila ^a   Bernheim, Joelle ^a  

^a MEIR MEDICAL CENTER   (Israel)

Author keywords

Aberrant crypts; Carcinogenesis; Large bowel

Indexed keywords

ARTICLE; COLON ADENOMA; COLON CARCINOGENESIS; COLON CARCINOMA; CONTROLLED STUDY; CRYPT CELL; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY;

EID: 0031944450     PISSN: 00468177     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0046-8177(98)90062-4     Document Type: Article

References (38)

1. Fearon ER, Vogelstein B: A genetic model for colorectal tumorigenesis. Cell 661:759-767, 1990
2. Shpitz B, Medline A, Stern H: The adenoma-carcinoma sequence, in Surgery of the Colon, Rectum and Anus. Philadelphia, PA, Saunders, 1995, pp 552-564
3. Kuramoto S, Oohara T: How do colorectal cancers develop? Cancer 75:1534-1538, 1995
4. Owen DA: Flat adenoma, flat carcinoma and de novo carcinoma of colon. Cancer 77:3-6, 1996
5. Kuramoto S, Osamu I, Sakai S, et al: Depressed adenoma in the large intestine. Dis Colon Rectum 33:108-112, 1990
6. Oohara T, Ogino A, Tohma H: Microscopic adenoma in nonpolyposis coli: Incidence and relation to basal cells and lymphoid follicles. Dis Colon Rectum 24:120-126, 1981
7. Kubota O, Kino I, Kimura T, et al: Nonpolypoid adenomas and adenocarcinomas found in background mucosa of surgically resected colons. Cancer 77:621-626, 1996
8. Collins RH, Feldman M, Fordtran SJ: Colon cancer, dysplasia, and surveillance in patients with ulcerative colitis. N Engl J Med 316:1654-1658, 1987
9. Bird RP: Observation and quantification of aberrant crypts in the murine colon treated with a colon carcinogen: Preliminary findings. Cancer Lett 37:147-151, 1987
10. McLellan EA, Bird RP: Aberrant crypts: Potential preneoplastic lesions in the murine mucosa. Cancer Res 48:6187-6192, 1988
11. McLellan EA, Medline A, Bird RP: Sequential analyses of the growth and morphologic characteristics of aberrant crypt foci: Putative preneoplastic lesions. Cancer Res 51:5270-5274, 1991
12. Shpitz B, Hay K, Medline A, et al: The natural history of aberrant crypt foci: A surgical approach. Dis Colon Rectum 39:763-767, 1996
13. Wagovich MJ, Chen C, Jimenez A, et al: Aberrant crypts as a biomarker for colon cancer: Evaluation of potential chemopreventive agents in the rat. Cancer Epidemiol Biomarkers Prev 5:355-360, 1996
14. Pretlow TP, Barrow BJ, Scott Ashton WC, et al: Aberrant crypt foci: Putative preneoplastic foci in human colonic mucosa. Cancer Res 51:1564-1567, 1991
15. Roncucci L, Stamp D, Medline A, et al: Identification and quantification of aberrant crypt foci and microadenomas in the human colon. HUM PATHOL 22:287-294, 1991
16. Pretlow TP, O'Riordan MN, Pretlow TG, et al: Aberrant crypts in human colonic mucosa: Putative preneoplastic lesions. J Cell Biochem 16G:55-62, 1992
17. Augenlicht HL, Richards C, Corner G, et al: Evidence for genomic instability in human colonic aberrant crypt foci. Oncogene 12:1767-1772, 1996
18. Smith AJ, Stern HS, Penner M, et al: Somatic APC and K-ras codon 12 mutations in aberrant crypt foci from human colons. Cancer Res 54:5527-5530, 1994
19. Pretlow TP, Roukhadze EV, O'Riordan MN, et al: Carcinoembryonic antigen in human colonie aberrant crypt foci. Gastroenterology 107:1719-1725, 1994
20. Pretlow TP, Brasitus TA, Fulton NS, et al: K-ras mutations in putative preneoplastic lesions in human colons. J Natl Cancer Inst 85:2004-2007, 1993
21. Kubota O, Kino I: Depressed adenomas of the colon in familial adenomatous polyposis. Am J Surg Pathol 19:318-327, 1995
22. Cattoretti G, Pileri S, Parravicini C, et al: Antigen unmasking on formalin-fixed, paraffin-embedded tissue sections. J Pathol 171:83-98, 1993
23. Polyak K, Hamilton SR, Vogelstein B, et al: Early alteration of cell-cycle-regulated gene expression in colorectal neoplasia. Am J Pathol 149:381-387, 1996
24. Heinen CD, Shivapurkar N, Tang Z, et al: Microsatellite instability in aberrant crypt foci from human colons. Cancer Res 56:5339-5341, 1996
25. Ponz de Lion M, Roncucci L, Di Donato P, et al: Pattern of epithelial cell proliferation in colorectal mucosa of normal subjects and of patients with adenomatous polyps and cancer of the large bowel. Cancer Res 48:4121-4126, 1988
26. Yamashita N, Munamoto T, Ochiai A, et al: Frequent and characteristic K-ras activation and absence of p53 protein accumulation in aberrant crypt foci of the colon. Gastroenterology 108:434-440, 1995
27. Otori K, Sugiyama K, Hasebe T, et al: Emergence of adenomatous aberrant crypt foci (ACF) from hyperplastic ACF with concomitant increase in cell proliferation. Cancer Res 55:4743-4746, 1995
28. Pretlow TP: Aberrant crypt foci and K-ras mutations: Earliest recognized players or innocent bystanders in colon carcinogenesis. Gastroenterology 108:600-603, 1995 (editorial)
29. Roncucci L, Pedroni M, Fante R, et al: Cell kinetic evaluation of human colonic crypts. Cancer Res 53:3726-3729, 1993
30. Barnes DM, Gillett CE: Determination of cell proliferation. J Clin Pathol 48.-M2-M5, 1995
31. Morris GF, Mathews MB: Regulation of proliferating cell nuclear antigen during cell cycle. J Biol Chem 264:13856-13864, 1989
32. Tahan SR, Wei Y, Ling P, et al: Influence of formalin fixation time and tissue processing method on immunoreactivity of monoclonal antibody PC10 for proliferating cell nuclear antigen. Mod Pathol 8:177-182, 1995
33. Kelleher L, Magee HM, Dervan PA: Evaluation of cell-proliferation antibodies reactive in paraffin sections. Appl Immunohistochem 2:164-170, 1994
34. Coltera MD, Skelly M, Gown AM: Anti-PCNA antibody yelds unreliable proliferation indices in routinely processed, deparafinized, formalin-fixed tissue. Appl Immunohistochem 1:193-200, 1993
35. Carter JW, Lancaster HK, Hardman WE, et al: Distribution of intestine-associated lymphoid tissue, aberrant crypt foci and tumors in the large intestine of 1,2-dimethylhydrazine-treated mice. Cancer Res 54:4304-4307, 1994
36. Hammann A, Arveux P, Martin M: Effect of gut-associated lymphoid tissue on cellular proliferation in proximal and distal colon of the rat. Dig Dis Sci 37:1099-1104, 1992
37. Araki K, Ogata T, Kobayashi M, et al: A morphological study on the histogenesis of human colorectal hyperplastic polyps. Gastroenterology 109:1468-1474, 1995
38. Oohara T, Ogino A, Tohma H: Microscopic adenoma in nonpolyposis coli. Dis Colon Rectum 24:120-126, 1988