Activated platelet-derived growth factor β receptor and Ras-mitogen-activated protein kinase pathway in natural bovine urinary bladder carcinomas

Veterinary Journal

Volumn 191, Issue 3, 2012, Pages 393-395

  Corteggio, Annunziata ^a   Di Geronimo, Ornella ^a   Roperto, Sante ^a   Roperto, Franco ^a   Borzacchiello, Giuseppe ^a  

^a UNIVERSITY OF NAPLES FEDERICO II   (Italy)

Author keywords

Bovine papillomavirus; Platelet derived growth factor; Urinary bladder tumours

Indexed keywords

GROWTH FACTOR RECEPTOR BOUND PROTEIN 2; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PLATELET DERIVED GROWTH FACTOR BETA RECEPTOR; RAS PROTEIN; SOS PROTEIN;

ANIMAL TISSUE; ARTICLE; BLADDER CARCINOMA; CANCER GRADING; CONTROLLED STUDY; COW; ENZYME ACTIVATION; IMMUNOPRECIPITATION; NONHUMAN; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; WESTERN BLOTTING;

ANIMALS; CARCINOMA; CATTLE; GENE EXPRESSION REGULATION, NEOPLASTIC; MAP KINASE SIGNALING SYSTEM; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; RAS PROTEINS; RECEPTOR, PLATELET-DERIVED GROWTH FACTOR BETA; URINARY BLADDER NEOPLASMS;

BOVINAE; BOVINE PAPILLOMAVIRUS; BOVINE PARVOVIRUS;

EID: 84857238386     PISSN: 10900233     EISSN: 15322971     Source Type: Journal    
DOI: 10.1016/j.tvjl.2011.03.019     Document Type: Article

References (11)

1. Borzacchiello G., Iovane G., Marcante M.L., Poggiali F., Roperto F., Roperto S., Venuti A. Presence of bovine papillomavirus type 2 DNA and expression of the viral oncoprotein E5 in naturally occurring urinary bladder tumours in cows. Journal of General Virology 2003, 84:2921-2926.
2. Borzacchiello G., Russo V., Gentile F., Roperto F., Venuti A., Nitsch L., Campo M.S., Roperto S. Bovine papillomavirus E5 oncoprotein binds to the activated form of the platelet-derived growth factor β receptor in naturally occurring bovine urinary bladder tumours. Oncogene 2006, 25:1251-1260.
3. Campo M.S., Jarrett W.F., Barron R., O'Neil B.W., Smith K.T. Association of bovine papillomavirus type 2 and bracken fern with bladder cancer in cattle. Cancer Research 1992, 52:6898-6904.
4. Corteggio A., Urraro C., Roperto F., Borzacchiello G. Phoshatidylinositol-3 kinase-AKT pathway, phospho-JUN and phospho-JNK expression in naturally occurring bovine urinary bladder tumours. Journal of Comparative Pathology 2010, 143:173-178.
5. Dance M., Montagner A., Salles J.P., Yart A., Raynal P. The molecular functions of Shp2 in the Ras/mitogen-activated protein kinase (ERK1/2) pathway. Cellular Signalling 2008, 20:453-459.
6. Di Maio D., Mattoon D. Mechanisms of cell transformation by papillomavirus E5 proteins. Oncogene 2001, 20:7866-7873.
7. Laurila J.P., Castellone M.D., Curcio A., Laatikaineen L.E., Haaparanta-Solin M., Gronroos T.J., Marjamaki P., Martikaineen S., Santoro M., Laukkaneen M.O. Extracellular superoxide dismutase is a growth regulatory mediator of tissue injury recovery. Molecular Therapy 2009, 17:448-454.
8. Lokker N.A., Sullivan C.M., Hollenbach S.J., Israel M.A., Giese N.A. Platelet-derived growth factor (PDGF) autocrine signaling regulates survival and mitogenic pathways in glioblastoma cells: evidence that the novel PDGF-C and PDGF-D ligands may play a role in the development of brain tumours. Cancer Research 2002, 62:3729-3735.
9. Kip1 inhibition of GRB2-SOS formation can regulate Ras activation. Molecular and Cellular Biology 2003, 23:3735-3752.
10. Petti L.M., Ricciardi E.C., Page H.J., Porter K.A. Transforming signals resulting from sustained activation of the PDGFβ receptor in mortal human fibroblasts. Journal of Cell Science 2008, 8:1172-1182.
11. Roperto S., Borzacchiello G., Brun R., Leonardi L., Maiolino P., Martano M., Paciello O., Papparella S., Restucci B., Russo V., Salvatore G., Urraro C., Roperto F. A review of bovine urothelial tumours and tumour-like lesions of the urinary bladder. Journal of Comparative Pathology 2010, 142:95-108.