New vistas in opioid control of pain

Current Opinion in Pharmacology

Volumn 12, Issue 1, 2012, Pages 87-91

  Mizoguchi, Hirokazu ^a   Watanabe, Chizuko ^a   Sakurada, Tsukasa ^b   Sakurada, Shinobu ^a  

^a TOHOKU PHARMACEUTICAL UNIVERSITY   (Japan)

^b DAIICHI UNIVERSITY OF PHARMACY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

DYNORPHIN; ENDOMORPHIN 1; ENDOMORPHIN 2; ENKEPHALIN[2 DEXTRO ALANINE 4 METHYLPHENYLALANINE 5 GLYCINE]; MESSENGER RNA; MORPHINE; MU OPIATE RECEPTOR; MU OPIATE RECEPTOR AGONIST; NARCOTIC ANALGESIC AGENT; OXYCODONE;

ANALGESIC ACTIVITY; BINDING AFFINITY; DRUG DEPENDENCE; DRUG EFFICACY; DRUG RECEPTOR BINDING; DRUG SELECTIVITY; DRUG TARGETING; GENETIC VARIABILITY; HUMAN; MOLECULAR CLONING; MORPHINE ADDICTION; NEUROPATHIC PAIN; NOCICEPTION; NONHUMAN; PAIN; PRIORITY JOURNAL; PROTEIN SECRETION; RECEPTOR UPREGULATION; REVIEW; SPLICING DEFECT;

ANALGESICS, OPIOID; GENE EXPRESSION REGULATION; GENETIC VARIATION; HUMANS; PAIN; RECEPTORS, OPIOID;

EID: 84857238243     PISSN: 14714892     EISSN: 14714973     Source Type: Journal    
DOI: 10.1016/j.coph.2011.10.020     Document Type: Review

References (54)

1. N. Dietis, D.J. Rowbotham, and D.G. Lambert Opioid receptor subtypes: fact or artifact? Br J Anaesth 107 2011 8 18
2. A. Mansour, C.A. Fox, S. Burke, H. Akil, and S.J. Watson Immunohistochemical localization of the cloned μ opioid receptor in the rat CNS J Chem Neuroanat 8 1995 283 305
3. S. Mense Basic neurobiologic mechanisms of pain and analgesia Am J Med 75 1983 4 14
4. G.W. Pasternak, and P.J. Wood Multiple μ opiate receptors Life Sci 38 1986 1889 1898
5. B.L. Wolozin, and G.W. Pasternak Classification of multiple morphine and enkephalin binding sites in the central nervous system Proc Natl Acad Sci USA 78 1981 6181 6185
6. E.F. Hahn, and G.W. Pasternak Naloxonazine, a potent, long-lasting inhibitor of opiate binding sites Life Sci 31 1982 1385 1388
7. G.W. Pasternak, A.R. Gintzler, R.A. Houghten, G.S. Ling, R.R. Goodman, K. Spiegel, S. Nishimura, N. Johnson, and L.D. Recht Biochemical and pharmacological evidence for opioid receptor multiplicity in the central nervous system Life Sci 33 Suppl. 1 1983 167 173
8. 1-opioid receptors to morphine-induced antinociception Eur J Pharmacol 369 1999 183 187
9. S. Sakurada, J.E. Zadina, A.J. Kastin, S. Katsuyama, T. Fujimura, K. Murayama, M. Yuki, H. Ueda, and T. Sakurada Differential involvement of μ-opioid receptor subtypes in endomorphin-1- and -2-induced antinociception Eur J Pharmacol 372 1999 25 30
10. 2-opioid receptor antagonist in the mouse J Pharmacol Exp Ther 312 2005 1075 1081
11. 1-opioid receptors on the Tyr-d-Arg-Phe-sarcosine-induced antinociception Eur J Pharmacol 540 2006 67 72
12. 2 discriminate different μ-opioid receptor mediated antinociception in mice Br J Pharmacol 137 2002 1143 1146
13. 2 discriminates among antinociception in mice mediated by different classes of μ-opioid receptors Eur J Pharmacol 563 2007 109 116
14. 1-opioid receptors in spinal antinociception by endomorphin-2 J Pharmacol Exp Ther 317 2006 362 368
15. Y. Chen, A. Mestek, J. Liu, A. Hurley, and L. Yu Molecular cloning and functional expression of a μ-opioid receptor from rat brain Mol Pharmacol 44 1993 8 12
16. J.B. Wang, Y. Imai, C.M. Eppler, P. Gregor, C.E. Spivak, and G.R. Uhl μ Opiate receptor: cDNA cloning and expression Proc Natl Acad Sci USA 90 1993 10230 10234
17. Y.-X. Pan, J. Xu, L. Mahurter, E. Bolan, M. Xu, and G.W. Pasternak Generation of the μ opioid receptor (MOR-1) protein by three new splice variants of the Oprm gene Proc Natl Acad Sci USA 98 2001 14084 14089
18. T.-M. Kvam, C. Baar, T.T. Rakvg, S. Kaasa, H.E. Krokan, and F. Skorpen Genetic analysis of the murine μ opioid receptor: increased complexity of Oprm gene splicing J Mol Med 82 2004 250 255
19. Y.-X. Pan, J. Xu, E. Bolan, H.S. Moskowitz, M. Xu, and G.W. Pasternak Identification of four novel exon 5 splice variants of the mouse μ-opioid receptor gene: functional consequences of C-terminal splicing Mol Pharmacol 68 2005 866 875
20. G.A. Doyle, X.R. Sheng, S.S. Lin, D.M. Press, D.E. Grice, R.J. Buono, T.N. Ferraro, and W.H. Berrettini Identification of three mouse μ-opioid receptor (MOR) gene (Oprm1) splice variants containing a newly identified alternatively spliced exon Gene 388 2007 135 147
21. G.A. Doyle, X.R. Sheng, S.S. Lin, D.M. Press, D.E. Grice, R.J. Buono, T.N. Ferraro, and W.H. Berrettini Identification of five mouse μ-opioid receptor (MOR) gene (Oprm1) splice variants containing a newly identified alternatively spliced exon Gene 395 2007 98 107
22. Y.-X. Pan, J. Xu, E. Bolan, C. Abbadie, A. Chang, A. Zuckerman, G. Rossi, and G.W. Pasternak Identification and characterization of three new alternatively spliced μ-opioid receptor isoforms Mol Pharmacol 56 1999 396 403
23. Y.-X. Pan, J. Xu, E. Bolan, A. Chang, L.A. Mahurter, G. Rossi, and G.W. Pasternak Isolation and expression of a novel alternatively spliced μ opioid receptor isoform, MOR-1F FEBS Lett 466 2000 337 340
24. H. Mizoguchi, C. Watanabe, T. Higashiya, S. Takeda, K. Moriyama, A. Yonezawa, T. Sato, T. Komatsu, T. Sakurada, and S. Sakurada Involvement of mouse μ-opioid receptor splice variants in the spinal antinociception induced by the dermorphin tetrapeptide analog amidino-TAPA Eur J Pharmacol 651 2011 66 72
25. H. Mizoguchi, G. Bagetta, T. Sakurada, and S. Sakurada Dermorphin tetrapeptide analogs as potent and long-lasting analgesics with pharmacological profiles distinct from morphine Peptides 32 2011 421 427
26. J.E. Zadina, L. Hackler, L.J. Ge, and A.J. Kastin A potent and selective endogenous agonist for the μ-opiate receptor Nature 386 1997 499 502
27. L.F. Tseng, M. Narita, C. Suganuma, H. Mizoguchi, M. Ohsawa, H. Nagase, and J.P. Kampine Differential antinociceptive effects of endomorphin-1 and endomorphin-2 in the mouse J Pharmacol Exp Ther 292 2000 576 583
28. S. Sakurada, T. Hayashi, M. Yuhki, T. Orito, J.E. Zadina, A.J. Kastin, T. Fujimura, K. Murayama, C. Sakurada, and T. Sakurada Differential antinociceptive effects induced by intrathecally administered endomorphin-1 and endomorphin-2 in the mouse Eur J Pharmacol 427 2001 203 210
29. M. Ohsawa, H. Mizoguchi, M. Narita, H. Nagase, J.P. Kampine, and L.F. Tseng Differential antinociception induced by spinally administered endomorphin-1 and endomorphin-2 in the mouse J Pharmacol Exp Ther 298 2001 592 597
30. 1-opioid receptor on supraspinal antinociception of endomorphin-2 Peptides 29 2008 1554 1560
31. 1]DALDA J Pharmacol Exp Ther 305 2003 696 702
32. 1-opioid receptors and dynorphin B to the antinociception induced by Tyr-d-Arg-Phe-Sar Peptides 27 2006 2786 2793
33. H. Mizoguchi, C. Watanabe, H. Watanabe, K. Moriyama, B. Sato, K. Ohwada, A. Yonezawa, T. Sakurada, and S. Sakurada Involvement of endogenous opioid peptides in the antinociception induced by the novel dermorphin tetrapeptide analog amidino-TAPA Eur J Pharmacol 560 2007 150 159
34. A. Herz, and R. Spanagel Endogenous opioids and addiction L.F. Tseng, The Pharmacology of Opioid Peptides 1995 Harwood Academic Publishers 445 462
35. R. Spanagel, A. Herz, and T.S. Shippenberg Opposing tonically active endogenous opioid systems modulate the mesolimbic dopaminergic pathway Proc Natl Acad Sci USA 89 1992 2046 2050
36. R. Spanagel, A. Herz, and T.S. Shippenberg The effects of opioid peptides on dopamine release in the nucleus accumbens: an in vivo microdialysis study J Neurochem 55 1990 1734 1740
37. M. Funada, T. Suzuki, M. Narita, M. Misawa, and H. Nagase Blockade of morphine reward through the activation of κ-opioid receptors in mice Neuropharmacology 32 1993 1315 1323
38. M. Narita, S. Ozaki, M. Ioka, H. Mizoguchi, H. Nagase, L.F. Tseng, and T. Suzuki Different motivational effects induced by the endogenous μ-opioid receptor ligands endomorphin-1 and -2 in the mouse Neuroscience 105 2001 213 218
39. H.E. Wu, R.S. MacDougall, A.D. Clithero, R.J. Leitermann, M. Terashvili, and L.F. Tseng Opposite conditioned place preference responses to endomorphin-1 and endomorphin-2 in the mouse Neurosci Lett 365 2004 157 161
40. H. Mizoguchi, C. Watanabe, S. Osada, M. Yoshioka, Y. Aoki, S. Natsui, A. Yonezawa, S. Kanno, M. Ishikawa, and T. Sakurada Lack of a rewarding effect and a locomotor-enhancing effect of the selective μ-opioid receptor agonist amidino-TAPA Psychopharmacology (Berl) 212 2010 215 225
41. D. Yarnitsky, and E. Eisenberg Neuropathic pain: between positive and negative ends Pain Forum 7 1998 241 242
42. S. Arné, and B.A. Meyerson Lack of analgesic effect of opioids on neuropathic and idiopathic forms of pain Pain 33 1988 11 23
43. R.K. Portenoy, K.M. Foley, and C.E. Inturrisi The nature of opioid responsiveness and its implications for neuropathic pain: new hypotheses derived from studies of opioid infusions Pain 43 1990 273 286
44. E. Eisenberg, E.D. McNicol, and D.B. Carr Efficacy of μ-opioid agonists in the treatment of evoked neuropathic pain: systematic review of randomized controlled trials Eur J Pain 10 2006 667 676
45. C.P.N. Watson, and N. Babul Efficacy of oxycodone in neuropathic pain: a randomized trial in postherpetic neuralgia Neurology 50 1998 1837 1841
46. C.P. Watson, D. Moulin, J. Watt-Watson, A. Gordon, and J. Eisenhoffer Controlled-release oxycodone relieves neuropathic pain: a randomized controlled trial in painful diabetic neuropathy Pain 105 2003 71 78
47. M. Narita, A. Nakamura, M. Ozaki, S. Imai, K. Miyoshi, M. Suzuki, and T. Suzuki Comparative pharmacological profiles of morphine and oxycodone under a neuropathic pain-like state in mice: evidence for less sensitivity to morphine Neuropsychopharmacology 33 2008 1097 1112
48. C. Nozaki, A. Saitoh, N. Tamura, and J. Kamei Antinociceptive effect of oxycodone in diabetic mice Eur J Pharmacol 524 2005 75 79
49. C.K. Nielsen, F.B. Ross, S. Lotfipour, K.S. Saini, S.R. Edwards, and M.T. Smith Oxycodone and morphine have distinctly different pharmacological profiles: radioligand binding and behavioural studies in two rat models of neuropathic pain Pain 132 2007 289 300
50. B. Przewłocka, J. Mika, D. Labuz, G. Toth, and R. Przewłocki Spinal analgesic action of endomorphins in acute, inflammatory and neuropathic pain in rats Eur J Pharmacol 367 1999 189 196
51. R. Przewłocki, D. Labuz, J. Mika, B. Przewłocka, C. Tomboly, and G. Toth Pain inhibition by endomorphins Ann NY Acad Sci 897 1999 154 164
52. D. Wolfe, S. Hao, J. Hu, R. Srinivasan, J. Goss, M. Mata, D.J. Fink, and J.C. Glorioso Engineering an endomorphin-2 gene for use in neuropathic pain therapy Pain 133 2007 29 38
53. D. Wolfe, M. Mata, and D.J. Fink A human trial of HSV-mediated gene transfer for the treatment of chronic pain Gene Ther 16 2009 455 460
54. H. Mizoguchi, C. Watanabe, A. Yonezawa, and S. Sakurada New therapy for neuropathic pain Int Rev Neurobiol 85 2009 249 460