Synthesis, evaluation and docking studies on 3-alkoxy-4-methanesulfonamido acetophenone derivatives as non ulcerogenic anti-inflammatory agents

European Journal of Medicinal Chemistry

Volumn 49, Issue , 2012, Pages 397-405

  Bali, Alka ^a   Ohri, Ruchika ^a   Deb, Pran Kishore ^a  

^a PANJAB UNIVERSITY   (India)

Author keywords

3D similarity; Anti inflammatory activity; Carrageenan induced paw edema; Docking; Field align; In silico

Indexed keywords

1 (4 AMINO 3 BUTOXYPHENYL)ETHANONE; 1 (4 AMINO 3 CYCLOHEXYLOXYPHENYL)ETHANONE; 1 (4 AMINO 3 HYDROXYPHENYL)ETHANONE; 1 (4 AMINO 3 PENTOXYPHENYL)ETHANONE; 1 (4 MINO 3 HEXOXYPHENYL)ETHANONE; 3 ALKOXY 4 METHANESULFONAMIDO ACETOPHENONE DERIVATIVE; 4 [5 (4 BROMOPHENYL) 3 TRIFLUOROMETHYL 1H PYRAZOL 1 YL]BENZENESULFONAMIDE; 6 ACETYL BENZO[D]OXAZOL 2 (3H) ONE; ACETOPHENONE DERIVATIVE; ANTIINFLAMMATORY AGENT; CARRAGEENAN; CYCLOOXYGENASE 2; INDOMETACIN; N (4 ACETYL 2 BUTOXYPHENYL)METHANESULFONAMIDE; N (4 ACETYL 2 CYCLOHEXYLOXYPHENYL)METHANESULFONAMIDE; N (4 ACETYL 2 HEXOXYPHENYL)METHANESULFONAMIDE; N (4 ACETYL 2 PENTOXYPHENYL)METHANESULFONAMIDE; NIMESULIDE; ROFECOXIB; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; MOLECULAR DOCKING; NONHUMAN; PAW EDEMA; PHYSICAL CHEMISTRY; RAT;

ACETOPHENONES; ANIMALS; ANTI-INFLAMMATORY AGENTS; CARRAGEENAN; CYCLOOXYGENASE 2; EDEMA; MODELS, MOLECULAR; PROTEIN BINDING; RATS; RATS, WISTAR; STOMACH ULCER; SULFONAMIDES;

EID: 84857237998     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2012.01.018     Document Type: Article

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