High throughput, cell type-specific analysis of key proteins in human endometrial biopsies of women from fertile and infertile couples

Human Reproduction

Volumn 27, Issue 3, 2012, Pages 814-828

  Leach, Richard E ^a   Jessmon, Philip ^b,c   Coutifaris, Christos ^d   Kruger, Michael ^b   Myers, Evan R ^e   Ali Fehmi, Rouba ^b   Carson, Sandra A ^f   Legro, Richard S ^g   Schlaff, William D ^h   Carr, Bruce R ⁱ   Steinkampf, Michael P ^j   Silva, Susan ^e   Leppert, Phyllis C ^e   Giudice, Linda ^k   Diamond, Michael P ^b   Armant, D Randall ^b,c  

^a MICHIGAN STATE UNIVERSITY   (United States)

^b WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

^d UNIVERSITY OF PENNSYLVANIA   (United States)

^e DUKE UNIVERSITY MEDICAL CENTER   (United States)

^f BROWN UNIVERSITY   (United States)

^g PENN STATE COLLEGE OF MEDICINE   (United States)

^h UNIVERSITY OF COLORADO   (United States)

ⁱ UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^j UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^k UNIVERSITY OF CALIFORNIA   (United States)

more..

Author keywords

developmental regulation; endometrium; idiopathic infertility; immunohistochemistry; protein expression

Indexed keywords

CALCITONIN; CXCL14 CHEMOKINE; HEPARIN BINDING EPIDERMAL GROWTH FACTOR; LEUKEMIA INHIBITORY FACTOR; PLACENTA PROTEIN 14; PROGESTERONE RECEPTOR B; TRANSCRIPTION FACTOR HOXA10;

ADULT; ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; ENDOMETRIUM BIOPSY; FEMALE; HIGH THROUGHPUT SEQUENCING; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; INFERTILITY; MAJOR CLINICAL STUDY; MENSTRUAL CYCLE; PROTEIN EXPRESSION; PROTEIN INTERACTION; PROTEIN LOCALIZATION; QUANTITATIVE HISTOCHEMISTRY;

EID: 84857206120     PISSN: 02681161     EISSN: 14602350     Source Type: Journal    
DOI: 10.1093/humrep/der436     Document Type: Article

References (104)

1. Aghajanova L, Velarde MC, Giudice LC. Altered gene expression profiling in endometrium: evidence for progesterone resistance. Semin Reprod Med 2010;28:51-58.
2. Arimoto T, Katagiri T, Oda K, Tsunoda T, Yasugi T, Osuga Y, Yoshikawa H, Nishii O, Yano T, Taketani Y et al. Genome-wide cDNA microarray analysis of gene-expression profiles involved in ovarian endometriosis. Int J Oncol 2003;22:551-560.
3. Armant DR, Wang J, Liu Z. Intracellular signaling in the developing blastocyst as a consequence of the maternal-embryonic dialogue. Semin Reprod Med 2000;18:273-287. (Pubitemid 32240059)
4. Armant DR, Kilburn BA, Petkova A, Edwin SS, Duniec-Dmuchowski ZM, Edwards HJ, Romero R, Leach RE. Human trophoblast survival at low oxygen concentrations requires metalloproteinase-mediated shedding of heparin-binding EGF-like growth factor. Development 2006; 133:751-759.
5. Arnett-Mansfield RL, DeFazio A, Mote PA, Clarke CL. Subnuclear distribution of progesterone receptors A and B in normal and malignant endometrium. J Clin Endocrinol Metab 2004;89:1429-1442. (Pubitemid 38368448)
6. Arnett-Mansfield RL, Graham JD, Hanson AR, Mote PA, Gompel A, Scurr LL, Gava N, de Fazio A, Clarke CL. Focal subnuclear distribution of progesterone receptor is ligand dependent and associated with transcriptional activity. Mol Endocrinol 2007;21:14-29. (Pubitemid 46041688)
7. Benson GV, Lim H, Paria BC, Satokata I, Dey SK, Maas RL. Mechanisms of reduced fertility in Hoxa-10 mutant mice: uterine homeosis and loss of maternal Hoxa-10 expression. Development 1996;122:2687-2696. (Pubitemid 26326501)
8. Bischof P. Three pregnancy proteins (PP12, PP14, and PAPP-A): their biological and clinical relevance. Am J Perinatol 1989;6:110-116. (Pubitemid 19122597)
9. Cermik D, Karaca M, Taylor HS. HOXA10 expression is repressed by progesterone in the myometrium: differential tissue-specific regulation of HOX gene expression in the reproductive tract. J Clin Endocrinol Metab 2001;86:3387-3392. (Pubitemid 32673512)
10. Coutifaris C, Myers ER, Guzick DS, Diamond MP, Carson SA, Legro RS, McGovern PG, Schlaff WD, Carr BR, Steinkampf MP et al. Histological dating of timed endometrial biopsy tissue is not related to fertility status. Fertil Steril 2004;82:1264-1272. (Pubitemid 39469442)
11. Daftary GS, Kayisli U, Seli E, Bukulmez O, Arici A, Taylor HS. Salpingectomy increases peri-implantation endometrial HOXA10 expression in women with hydrosalpinx. Fertil Steril 2007;87:367-372. (Pubitemid 46176925)
12. Das SK, Wang XN, Paria BC, Damm D, Abraham JA, Klagsbrun M, Andrews GK, Dey SK. Heparin-binding EGF-like growth factor gene is induced in the mouse uterus temporally by the blastocyst solely at the site of its apposition: a possible ligand for interaction with blastocyst EGF-receptor in implantation. Development 1994; 120:1071-1083.
13. Diao HL, Li SJ, Wang HB, Yang ZM. Calcitonin immunostaining in monkey uterus during menstrual cycle and early pregnancy. Endocrine 2002; 18:75-78.
14. Dimitriadis E, Stoikos C, Stafford-Bell M, Clark I, Paiva P, Kovacs G, Salamonsen LA. Interleukin-11, IL-11 receptoralpha and leukemia inhibitory factor are dysregulated in endometrium of infertile women with endometriosis during the implantation window. J Reprod Immunol 2006;69:53-64. (Pubitemid 43144471)
15. Dimitriadis E, Sharkey AM, Tan YL, Salamonsen LA, Sherwin JR. Immunolocalisation of phosphorylated STAT3, interleukin 11 and leukaemia inhibitory factor in endometrium of women with unexplained infertility during the implantation window. Reprod Biol Endocrinol 2007;5:44.
16. Ding YQ, Zhu LJ, Bagchi MK, Bagchi IC. Progesterone stimulates calcitonin gene expression in the uterus during implantation. Endocrinology 1994; 135:2265-2274. (Pubitemid 24363927)
17. Ding T, Song H, Wang X, Khatua A, Paria BC. Leukemia inhibitory factor ligand-receptor signaling is important for uterine receptivity and implantation in golden hamsters (Mesocricetus auratus). Reproduction 2008;135:41-53.
18. Dominguez F, Avila S, Cervero A, Martin J, Pellicer A, Castrillo JL, Simon C. A combined approach for gene discovery identifies insulin-like growth factor-binding protein-related protein 1 as a new gene implicated in human endometrial receptivity. J Clin Endocrinol Metab 2003;88:1849-1857. (Pubitemid 36623414)
19. Dominguez F, Garrido-Gomez T, Lopez JA, Camafeita E, Quinonero A, Pellicer A, Simon C. Proteomic analysis of the human receptive versus non-receptive endometrium using differential in-gel electrophoresis and MALDI-MS unveils stathmin 1 and annexin A2 as differentially regulated. Hum Reprod 2009;24:2607-2617.
20. Eyster KM, Boles AL, Brannian JD, Hansen KA. DNA microarray analysis of gene expression markers of endometriosis. Fertil Steril 2002; 77:38-42. (Pubitemid 34093890)
21. Fazleabas AT. Progesterone resistance in a baboon model of endometriosis. Semin Reprod Med 2010;28:75-80.
22. Franco HL, Jeong JW, Tsai SY, Lydon JP, Demayo FJ. In vivo analysis of progesterone receptor action in the uterus during embryo implantation. Sem Cell Dev Biol 2008;19:178-186.
23. Gui Y, Zhang J, Yuan L, Lessey BA. Regulation of HOXA-10 and its expression in normal and abnormal endometrium. Mol Hum Reprod 1999;5:866-873. (Pubitemid 29406751)
24. Hambartsoumian E. Endometrial leukemia inhibitory factor (LIF) as a possible cause of unexplained infertility and multiple failures of implantation. Am J Reprod Immunol 1998;39:137-143. (Pubitemid 28062285)
25. Hannan NJ, Jones RL, White CA, Salamonsen LA. The chemokines, CX3CL1, CCL14, and CCL4, promote human trophoblast migration at the feto-maternal interface. Biol Reprod 2006;74:896-904.
26. Hannan NJ, Stephens AN, Rainczuk A, Hincks C, Rombauts LJ, Salamonsen LA. 2D-DiGE analysis of the human endometrial secretome reveals differences between receptive and nonreceptive states in fertile and infertile women. J Proteome Res 2010;9:6256-6264.
27. Henriquez S, Tapia A, Quezada M, Vargas M, Cardenas H, Rios M, Salvatierra AM, Croxatto H, Orihuela P, Zegers-Hochschild F et al. Deficient expression of monoamine oxidase A in the endometrium is associated with implantation failure in women participating as recipients in oocyte donation. Mol Hum Reprod 2006;12:749-754. (Pubitemid 44811653)
28. Hever A, Roth RB, Hevezi PA, Lee J, Willhite D, White EC, Marin EM, Herrera R, Acosta HM, Acosta AJ et al. Molecular characterization of human adenomyosis. Mol Hum Reprod 2006;12:737-748. (Pubitemid 44811652)
29. Horcajadas JA, Riesewijk A, Polman J, van Os R, Pellicer A, Mosselman S, Simon C. Effect of controlled ovarian hyperstimulation in IVF on endometrial gene expression profiles. Mol Hum Reprod 2005; 11:195-205. (Pubitemid 40662753)
30. Horita H, Kuroda E, Hachisuga T, Kashimura M, Yamashita U. Induction of prostaglandin E2 production by leukemia inhibitory factor promotes migration of first trimester extravillous trophoblast cell line, HTR-8/SVneo. Hum Reprod 2007;22:1801-1809. (Pubitemid 47062744)
31. Inagaki N, Stern C, McBain J, Lopata A, Kornman L, Wilkinson D. Analysis of intra-uterine cytokine concentration and matrix-metalloproteinase activity in women with recurrent failed embryo transfer. Hum Reprod 2003;18:608-615. (Pubitemid 36329334)
32. Jeschke U, Kunert-Keil C, Mylonas I, Hammer A, Schiessl B, Lomba I, Kuhn C, Schulze S, Friese K. Expression of glycodelin A in decidual tissue of preeclamptic, HELLP and intrauterine growth-restricted pregnancies. Virchows Arch 2005;446:360-368. (Pubitemid 40684428)
33. Jessmon P, Kilburn BA, Romero R, Leach RE, Armant DR. Function-specific intracellular signaling pathways downstream of heparin-binding eGF-like growth factor utilized by human trophoblasts. Biol Reprod 2010;82:921-929.
34. Kao LC, Germeyer A, Tulac S, Lobo S, Yang JP, Taylor RN, Osteen K, Lessey BA, Giudice LC. Expression profiling of endometrium from women with endometriosis reveals candidate genes for disease-based implantation failure and infertility. Endocrinology 2003;144:2870-2881. (Pubitemid 36819889)
35. Karande AA, Mukhopadhyay D, Jayachandran R, Sundarraj S, Alok A. Mechanism of the immunomodulatory activity of glycodelin. Indian J Physiol Pharmacol 2005;49:271-283. (Pubitemid 41059917)
36. Kilburn BA, Wang J, Duniec-Dmuchowski ZM, Leach RE, Romero R, Armant DR. Extracellular matrix composition and hypoxia regulate the expression of HLA-G and integrins in a human trophoblast cell line. Biol Reprod 2000;62:739-747. (Pubitemid 30118317)
37. Kim JJ, Taylor HS, Lu Z, Ladhani O, Hastings JM, Jackson KS, Wu Y, Guo SW, Fazleabas AT. Altered expression of HOXA10 in endometriosis: potential role in decidualization. Mol Hum Reprod 2007;13:323-332. (Pubitemid 47061643)
38. Kimber SJ. Leukaemia inhibitory factor in implantation and uterine biology. Reproduction 2005;130:131-145. (Pubitemid 41149801)
39. Kuang H, Chen Q, Fan X, Zhang Y, Zhang L, Peng H, Cao Y, Duan E. CXCL14 inhibits trophoblast outgrowth via a paracrine/autocrine manner during early pregnancy in mice. J Cell Physiol 2009a; 221:448-457.
40. Kuang H, Chen Q, Zhang Y, Zhang L, Peng H, Ning L, Cao Y, Duan E. The cytokine gene CXCL14 restricts human trophoblast cell invasion by suppressing gelatinase activity. Endocrinology 2009b;150: 5596-5605.
41. Kumar S, Zhu LJ, Polihronis M, Cameron ST, Baird DT, Schatz F, Dua A, Ying YK, Bagchi MK, Bagchi IC. Progesterone induces calcitonin gene expression in human endometrium within the putative window of implantation. J Clin Endocrinol Metab 1998;83:4443-4450. (Pubitemid 29100150)
42. Kumar S, Brudney A, Cheon YP, Fazleabas AT, Bagchi IC. Progesterone induces calcitonin expression in the baboon endometrium within the window of uterine receptivity. Biol Reprod 2003;68:1318-1323. (Pubitemid 36359120)
43. Lai TH, King JA, Shih Ie M, Vlahos NF, Zhao Y. Immunological localization of syndecan-1 in human endometrium throughout the menstrual cycle. Fertil Steril 2007;87:121-126. (Pubitemid 46013895)
44. Laird SM, Tuckerman EM, Dalton CF, Dunphy BC, Li TC, Zhang X. The production of leukaemia inhibitory factor by human endometrium: presence in uterine flushings and production by cells in culture. Hum Reprod 1997;12:569-574. (Pubitemid 27156457)
45. Leach RE, Khalifa R, Ramirez ND, Das SK, Wang J, Dey SK, Romero R, Armant DR. Multiple roles for heparin-binding epidermal growth factor-like growth factor are suggested by its cell-specific expression during the human endometrial cycle and early placentation. J Clin Endocrinol Metab 1999;84:3355-3363. (Pubitemid 30646968)
46. Leach RE, Romero R, Kim YM, Chaiworapongsa T, Kilburn B, Das SK, Dey SK, Johnson A, Qureshi F, Jacques S et al. Pre-eclampsia and expression of heparin-binding EGF-like growth factor. Lancet 2002; 360:1215-1219. (Pubitemid 35232721)
47. Leach RE, Kilburn B, Wang J, Liu Z, Romero R, Armant DR. Heparin-binding EGF-like growth factor regulates human extravillous cytotrophoblast development during conversion to the invasive phenotype. Dev Biol 2004;266:223-237. (Pubitemid 38102235)
48. Leach RE, Kilburn BA, Petkova A, Romero R, Armant DR. Diminished survival of human cytotrophoblast cells exposed to hypoxia/reoxygenation injury and associated reduction of heparin-binding epidermal growth factor-like growth factor. Am J Obstet Gynecol 2008; 198:471 e471-477; discussion 471 e477-478.
49. Lessey BA, Damjanovich L, Coutifaris C, Castelbaum A, Albelda SM, Buck CA. Integrin adhesion molecules in the human endometrium. Correlation with the normal and abnormal menstrual cycle. J Clin Invest 1992;90:188-195.
50. Lessey BA, Gui Y, Apparao KB, Young SL, Mulholland J. Regulated expression of heparin-binding EGF-like growth factor (HB-EGF) in the human endometrium: a potential paracrine role during implantation. Mol Reprod Dev 2002;62:446-455. (Pubitemid 34743056)
51. Li H, Chen S, Xing F. Expression of HOXA10 gene in human endometrium and its relationship with unexplained infertility. Zhonghua Fu Chan Ke Za Zhi 2002a;37:30-32.
52. Li Q, Wang J, Armant DR, Bagchi MK, Bagchi IC. Calcitonin down-regulates E-cadherin expression in rodent uterine epithelium during implantation. J Biol Chem 2002b;277:46447-46455. (Pubitemid 35417640)
53. Lydon JP, DeMayo FJ, Funk CR, Mani SK, Hughes AR, Montgomery CA Jr, Shyamala G, Conneely OM, O'Malley BW. Mice lacking progesterone receptor exhibit pleiotropic reproductive abnormalities. Genes Dev 1995;9:2266-2278.
54. Martel D, Psychoyos A. Estrogen receptors in the nidatory sites of the rat endometrium. Science 1981;211:1454-1455. (Pubitemid 11107908)
55. Martel D, Frydman R, Glissant M, Maggioni C, Roche D, Psychoyos A. Scanning electron microscopy of postovulatory human endometrium in spontaneous cycles and cycles stimulated by hormone treatment. J Endocrinol 1987;114:319-324. (Pubitemid 17100019)
56. Martin KL, Barlow DH, Sargent IL. Heparin-binding epidermal growth factor significantly improves human blastocyst development and hatching in serum-free medium. Hum Reprod 1998;13:1645-1652. (Pubitemid 28310508)
57. Matsuzaki S, Canis M, Vaurs-Barriere C, Pouly JL, Boespflug-Tanguy O, Penault-Llorca F, Dechelotte P, Dastugue B, Okamura K, Mage G. DNA microarray analysis of gene expression profiles in deep endometriosis using laser capture microdissection. Mol Hum Reprod 2004;10:719-728. (Pubitemid 39341594)
58. Matsuzaki S, Canis M, Pouly JL, Dechelotte P, Okamura K, Mage G. The macrophage stimulating protein/RON system: a potential novel target for prevention and treatment of endometriosis. Mol Hum Reprod 2005;11:345-349. (Pubitemid 41417867)
59. Matsuzaki S, Canis M, Pouly JL, Botchorishvili R, Dechelotte PJ, Mage G. Differential expression of genes in eutopic and ectopic endometrium from patients with ovarian endometriosis. Fertil Steril 2006;86:548-553. (Pubitemid 44321907)
60. Mezhevikina LM, Kapralova IV, Fesenko EE. Stimulating effect of recombinant cytokine LIF on the mouse blastocysts during implantation. Biomed Khim 2006;52:620-626. (Pubitemid 46212873)
61. Mikolajczyk M, Wirstlein P, Skrzypczak J. Leukaemia inhibitory factor and interleukin 11 levels in uterine flushings of infertile patients with endometriosis. Hum Reprod 2006;21:3054-3058. (Pubitemid 44811604)
62. Mikolajczyk M, Wirstlein P, Skrzypczak J. The impact of leukemia inhibitory factor in uterine flushing on the reproductive potential of infertile women-a prospective study. Am J Reprod Immunol 2007; 58:65-74. (Pubitemid 46939029)
63. Mirkin S, Nikas G, Hsiu JG, Diaz J, Oehninger S. Gene expression profiles and structural/functional features of the peri-implantation endometrium in natural and gonadotropin-stimulated cycles. J Clin Endocrinol Metab 2004;89:5742-5752. (Pubitemid 39523132)
64. Mirkin S, Arslan M, Churikov D, Corica A, Diaz JI, Williams S, Bocca S, Oehninger S. In search of candidate genes critically expressed in the human endometrium during the window of implantation. Hum Reprod 2005;20:2104-2117. (Pubitemid 41418492)
65. Mote PA, Balleine RL, McGowan EM, Clarke CL. Colocalization of progesterone receptors A and B by dual immunofluorescent histochemistry in human endometrium during the menstrual cycle. J Clin Endocrinol Metab 1999;84:2963-2971. (Pubitemid 30642036)
66. Mote PA, Balleine RL, McGowan EM, Clarke CL. Heterogeneity of progesterone receptors A and B expression in human endometrial glands and stroma. Hum Reprod 2000;15(Suppl. 3):48-56.
67. Mukhopadhyay D, Sundereshan S, Rao C, Karande AA. Placental protein 14 induces apoptosis in T cells but not in monocytes. J Biol Chem 2001; 276:28268-28273.
68. Mukhopadhyay D, SundarRaj S, Alok A, Karande AA. Glycodelin A, not glycodelin S, is apoptotically active. Relevance of sialic acid modification. J Biol Chem 2004;279:8577-8584. (Pubitemid 38295911)
69. Mulac-Jericevic B, Mullinax RA, DeMayo FJ, Lydon JP, Conneely OM. Subgroup of reproductive functions of progesterone mediated by progesterone receptor-B isoform. Science 2000;289:1751-1754.
70. Mulac-Jericevic B, Lydon JP, DeMayo FJ, Conneely OM. Defective mammary gland morphogenesis in mice lacking the progesterone receptor B isoform. Proc Natl Acad Sci USA 2003;100:9744-9749. (Pubitemid 37087012)
71. Mylonas I, Jeschke U, Kunert-Keil C, Shabani N, Dian D, Bauerfeind I, Kuhn C, Kupka MS, Friese K. Glycodelin A is expressed differentially in normal human endometrial tissue throughout the menstrual cycle as assessed by immunohistochemistry and in situ hybridization. Fertil Steril 2006;86:1488-1497. (Pubitemid 44602057)
72. Nikas G, Drakakis P, Loutradis D, Mara-Skoufari C, Koumantakis E, Michalas S, Psychoyos A. Uterine pinopodes as markers of the 'nidation window' in cycling women receiving exogenous oestradiol and progesterone. Hum Reprod 1995;10:1208-1213.
73. Noyes RW, Hertig AT, Rock J. Dating the endometrial biopsy. Fertil Steril 1950;1:3-17.
74. Okamoto N, Uchida A, Takakura K, Kariya Y, Kanzaki H, Riittinen L, Koistinen R, Seppala M, Mori T. Suppression by human placental protein 14 of natural killer cell activity. Am J Reprod Immunol 1991; 26:137-142.
75. Paria BC, Ma W, Tan J, Raja S, Das SK, Dey SK, Hogan BL. Cellular and molecular responses of the uterus to embryo implantation can be elicited by locally applied growth factors. Proc Natl Acad Sci USA 2001; 98:1047-1052. (Pubitemid 32121184)
76. Poornima BL, Karande AA. Differential sialylation regulates the apoptotic activity of glycodelin A. FEBS Lett 2007;581:4366-4370. (Pubitemid 47301865)
77. Punyadeera C, Dassen H, Klomp J, Dunselman G, Kamps R, Dijcks F, Ederveen A, de Goeij A, Groothuis P. Oestrogen-modulated gene expression in the human endometrium. Cell Mol Life Sci 2005; 62:239-250. (Pubitemid 40193048)
78. Qian K, Chen H, Wei Y, Hu J, Zhu G. Differentiation of endometrial stromal cells in vitro: down-regulation of suppression of the cell cycle inhibitor p57 by HOXA10?. Mol Hum Reprod 2005;11:245-251. (Pubitemid 40662809)
79. Quinn CE, Detmar J, Casper RF. Pinopodes are present in Lif null and Hoxa10 null mice. Fertil Steril 2007;88:1021-1028. (Pubitemid 47520612)
80. Riesewijk A, Martin J, van Os R, Horcajadas JA, Polman J, Pellicer A, Mosselman S, Simon C. Gene expression profiling of human endometrial receptivity on days LH+2 versus LH+7 by microarray technology. Mol Hum Reprod 2003;9:253-264. (Pubitemid 36748828)
81. Rutanen EM, Koistinen R, Seppala M, Julkunen M, Suikkari AM, Huhtala ML. Progesterone-associated proteins PP12 and PP14 in the human endometrium. J Steroid Biochem 1987;27:25-31. (Pubitemid 18059204)
82. Sato Y, Higuchi T, Yoshioka S, Tatsumi K, Fujiwara H, Fujii S. Trophoblasts acquire a chemokine receptor, CCR1, as they differentiate towards invasive phenotype. Development 2003;130:5519-5532. (Pubitemid 37484018)
83. Scotchie JG, Fritz MA, Mocanu M, Lessey BA, Young SL. Proteomic analysis of the luteal endometrial secretome. Reprod Sci 2009; 16:883-893.
84. Simon C, Oberye J, Bellver J, Vidal C, Bosch E, Horcajadas JA, Murphy C, Adams S, Riesewijk A, Mannaerts B et al. Similar endometrial development in oocyte donors treated with either high-or standard-dose GnRH antagonist compared to treatment with a GnRH agonist or in natural cycles. Hum Reprod 2005;20:3318-3327. (Pubitemid 41742507)
85. Skrzypczak J, Wirstlein P, Mikolajczyk M. Is glycodelin an important marker of endometrial receptivity?. Ginekol Pol 2005;76:770-781.
86. Song H, Lim H, Das SK, Paria BC, Dey SK. Dysregulation of EGF family of growth factors and COX-2 in the uterus during the preattachment and attachment reactions of the blastocyst with the luminal epithelium correlates with implantation failure in LIF-deficient mice. Mol Endocrinol 2000;14:1147-1161. (Pubitemid 32260477)
87. Stavreus-Evers A, Mandelin E, Koistinen R, Aghajanova L, Hovatta O, Seppala M. Glycodelin is present in pinopodes of receptive-phase human endometrium and is associated with down-regulation of progesterone receptor B. Fertil Steril 2006;85:1803-1811. (Pubitemid 43816422)
88. Stewart CL, Kaspar P, Brunet LJ, Bhatt H, Gadi I, Kontgen F, Abbondanzo SJ. Blastocyst implantation depends on maternal expression of leukaemia inhibitory factor. Nature 1992;359:76-79.
89. Talbi S, Hamilton AE, Vo KC, Tulac S, Overgaard MT, Dosiou C, Le Shay N, Nezhat CN, Kempson R, Lessey BA et al. Molecular phenotyping of human endometrium distinguishes menstrual cycle phases and underlying biological processes in normo-ovulatory women. Endocrinology 2006;147:1097-1121. (Pubitemid 43244341)
90. Tapia A, Gangi LM, Zegers-Hochschild F, Balmaceda J, Pommer R, Trejo L, Pacheco IM, Salvatierra AM, Henriquez S, Quezada M et al. Differences in the endometrial transcript profile during the receptive period between women who were refractory to implantation and those who achieved pregnancy. Hum Reprod 2008;23:340-351. (Pubitemid 351651238)
91. Taylor HS, Arici A, Olive D, Igarashi P. HOXA10 is expressed in response to sex steroids at the time of implantation in the human endometrium. J Clin Invest 1998;101:1379-1384. (Pubitemid 28166835)
92. Taylor HS, Bagot C, Kardana A, Olive D, Arici A. HOX gene expression is altered in the endometrium of women with endometriosis. Hum Reprod 1999;14:1328-1331. (Pubitemid 29224916)
93. Vigne JL, Hornung D, Mueller MD, Taylor RN. Purification and characterization of an immunomodulatory endometrial protein, glycodelin. J Biol Chem 2001;276:17101-17105.
94. Wang J, Rout UK, Bagchi IC, Armant DR. Expression of calcitonin receptors in mouse preimplantation embryos and their function in the regulation of blastocyst differentiation by calcitonin. Development 1998; 125:4293-4302. (Pubitemid 28528936)
95. Wang J, Mayernik L, Schultz JF, Armant DR. Acceleration of trophoblast differentiation by heparin-binding EGF-like growth factor is dependent on the stage-specific activation of calcium influx by ErbB receptors in developing mouse blastocysts. Development 2000; 127:33-44. (Pubitemid 30064386)
96. White CA, Zhang JG, Salamonsen LA, Baca M, Fairlie WD, Metcalf D, Nicola NA, Robb L, Dimitriadis E. Blocking LIF action in the uterus by using a PEGylated antagonist prevents implantation: a nonhormonal contraceptive strategy. Proc Natl Acad Sci USA 2007;104:19357-19362.
97. Wilcox AJ, Baird DD, Weinberg CR. Time of implantation of the conceptus and loss of pregnancy. N Engl J Med 1999;340:1796-1799. (Pubitemid 29266403)
98. Wu Y, Kajdacsy-Balla A, Strawn E, Basir Z, Halverson G, Jailwala P, Wang Y, Wang X, Ghosh S, Guo SW. Transcriptional characterizations of differences between eutopic and ectopic endometrium. Endocrinology 2006;147:232-246. (Pubitemid 43004277)
99. Xie H, Wang H, Tranguch S, Iwamoto R, Mekada E, Demayo FJ, Lydon JP, Das SK, Dey SK. Maternal heparin-binding-EGF deficiency limits pregnancy success in mice. Proc Natl Acad Sci USA 2007; 104:18315-18320. (Pubitemid 350210864)
100. Yanaihara A, Otsuka Y, Iwasaki S, Aida T, Tachikawa T, Irie T, Okai T. Differences in gene expression in the proliferative human endometrium. Fertil Steril 2005;83(Suppl. 1):1206-1215. (Pubitemid 40543505)
101. Yoo HJ, Barlow DH, Mardon HJ. Temporal and spatial regulation of expression of heparin-binding epidermal growth factor-like growth factor in the human endometrium: a possible role in blastocyst implantation. Dev Genet 1997;21:102-108. (Pubitemid 27381646)
102. Young SL, Lessey BA. Progesterone function in human endometrium: clinical perspectives. Semin Reprod Med 2010;28:5-16.
103. Zhu LJ, Bagchi MK, Bagchi IC. Attenuation of calcitonin gene expression in pregnant rat uterus leads to a block in embryonic implantation. Endocrinology 1998a;139:330-339. (Pubitemid 28166326)
104. Zhu LJ, Cullinan-Bove K, Polihronis M, Bagchi MK, Bagchi IC. Calcitonin is a progesterone-regulated marker that forecasts the receptive state of endometrium during implantation. Endocrinology 1998b;139: 3923-3934. (Pubitemid 28512276)