Design and synthesis of an Fmoc-SPPS-compatible amino acid building block mimicking the transition state of phosphohistidine phosphatase

Journal of Organic Chemistry

Volumn 77, Issue 4, 2012, Pages 2047-2052

  Eerland, Martijn F ^a   Hedberg, Christian ^a  

^a MAX PLANCK INSTITUTE OF MOLECULAR PHYSIOLOGY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID BUILDING BLOCKS; DEPHOSPHORYLATIONS; KEY FEATURE; PROOF OF CONCEPT; PROTECTIVE GROUP; SOLID PHASE PEPTIDE SYNTHESIS; TRANSITION-STATE;

AMINO ACIDS; PEPTIDES; SULFUR COMPOUNDS; SURFACE PLASMON RESONANCE;

PHOSPHATASES;

AMINO ACID; PHOSPHATASE; PHOSPHOHISTIDINE PHOSPHATASE; UNCLASSIFIED DRUG;

ARTICLE; CROSS COUPLING REACTION; DEPHOSPHORYLATION; METALLATION; PEPTIDE SYNTHESIS;

AMINO ACID SEQUENCE; AMINO ACIDS; DRUG DESIGN; ENZYME INHIBITORS; FLUORENES; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR MIMICRY; MOLECULAR SEQUENCE DATA; MOLECULAR STRUCTURE; PEPTIDES; PHOSPHORIC MONOESTER HYDROLASES; SOLID-PHASE SYNTHESIS TECHNIQUES; SULFONAMIDES;

EID: 84857202306     PISSN: 00223263     EISSN: 15206904     Source Type: Journal    
DOI: 10.1021/jo2025702     Document Type: Article

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