Insights into ubiquitin-conjugating enzyme/co-activator interactions from the structure of the Pex4p:Pex22p complex

EMBO Journal

Volumn 31, Issue 2, 2012, Pages 391-402

  Williams, Chris ^a   Van Den Berg, Marlene ^b   Panjikar, Santosh ^a,d   Stanley, Will A ^c   Distel, Ben ^b   Wilmanns, Matthias ^a  

^a EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Germany)

^b ACADEMIC MEDICAL CENTER   (Netherlands)

^c UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^d AUSTRALIAN SYNCHROTRON   (Australia)

Author keywords

E2 co activator complex; peroxisomal receptor recycling; Pex22p; Pex4p; ubiquitin conjugating enzyme structure

Indexed keywords

MEMBRANE PROTEIN; PEROXISOMAL IMPORT RECEPTOR PEX5P; PEROXISOMAL MEMBRANE PROTEIN PEX22P; PEROXISOME ASSOCIATED E2 ENZYME PEX4P; RECEPTOR; UBIQUITIN; UBIQUITIN CONJUGATING ENZYME; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENZYME ACTIVITY; ENZYME REGULATION; IN VITRO STUDY; IN VIVO STUDY; NONHUMAN; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN BINDING; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; UBIQUITINATION;

AMINO ACID SEQUENCE; CRYSTALLOGRAPHY, X-RAY; MEMBRANE PROTEINS; MEMBRANE TRANSPORT PROTEINS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MULTIENZYME COMPLEXES; PEPTIDE FRAGMENTS; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN INTERACTION MAPPING; PROTEIN PROCESSING, POST-TRANSLATIONAL; RECOMBINANT FUSION PROTEINS; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, AMINO ACID; STRUCTURE-ACTIVITY RELATIONSHIP; UBIQUITIN; UBIQUITINATION;

EID: 84857196028     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/emboj.2011.411     Document Type: Article

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