메뉴 건너뛰기




Volumn 120, Issue 5, 2012, Pages 752-764

A novel anti-inflammatory role for spleen-derived interleukin-10 in obesity-induced hypothalamic inflammation

Author keywords

hypothalamic inflammation; IL 10; Obesity; spleen

Indexed keywords

INTERLEUKIN 10; TUMOR NECROSIS FACTOR ALPHA;

EID: 84857194409     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2011.07617.x     Document Type: Article
Times cited : (31)

References (44)
  • 2
    • 36749080906 scopus 로고    scopus 로고
    • Inhibitory effects of lipopolysaccharide on hypothalamic nuclei implicated in the control of food intake
    • Becskei C., Riediger T., Hernadfavley N., Arsenijvic D., Luz T. A., and, Langhans W., (2008) Inhibitory effects of lipopolysaccharide on hypothalamic nuclei implicated in the control of food intake. Brain Behav. Immun. 22, 56-64.
    • (2008) Brain Behav. Immun. , vol.22 , pp. 56-64
    • Becskei, C.1    Riediger, T.2    Hernadfavley, N.3    Arsenijvic, D.4    Luz, T.A.5    Langhans, W.6
  • 3
    • 33845768784 scopus 로고    scopus 로고
    • Microglia-mediated neurotoxicity: Uncovering the molecular mechanisms
    • Block M. L., Zecca L., and, Hong J. S., (2007) Microglia-mediated neurotoxicity: uncovering the molecular mechanisms. Nat. Rev. Neurosci. 8, 57-69.
    • (2007) Nat. Rev. Neurosci. , vol.8 , pp. 57-69
    • Block, M.L.1    Zecca, L.2    Hong, J.S.3
  • 6
    • 17844401704 scopus 로고    scopus 로고
    • Anatomy and regulation of the central melanocortin system
    • Cone D. R., (2005) Anatomy and regulation of the central melanocortin system. Nat. Neurosci. 8, 571-578.
    • (2005) Nat. Neurosci. , vol.8 , pp. 571-578
    • Cone, D.R.1
  • 8
    • 24944438230 scopus 로고    scopus 로고
    • Consumption of a fat-rich diet activates a proinflamatory response and induces insulin resistance in the hypothalamus
    • De Souza C. T., Araujo E. P., Bordin S., Ashimine R., Zollner R. L., Boschero A. C., Saad M. J., and, Velloso L. A., (2005) Consumption of a fat-rich diet activates a proinflamatory response and induces insulin resistance in the hypothalamus. Endocrinology 146, 4192-4199.
    • (2005) Endocrinology , vol.146 , pp. 4192-4199
    • De Souza, C.T.1    Araujo, E.P.2    Bordin, S.3    Ashimine, R.4    Zollner, R.L.5    Boschero, A.C.6    Saad, M.J.7    Velloso, L.A.8
  • 12
    • 77649339778 scopus 로고    scopus 로고
    • Central interleukin-10 attenuates lipopolysaccharide-induced changes in food intake, energy expenditure and hypothalamic Fos expression
    • Hollis J. H., Lemus M., Evetts M. J., and, Oldfield B. J., (2010) Central interleukin-10 attenuates lipopolysaccharide-induced changes in food intake, energy expenditure and hypothalamic Fos expression. Neuropharmacology 58, 730-738.
    • (2010) Neuropharmacology , vol.58 , pp. 730-738
    • Hollis, J.H.1    Lemus, M.2    Evetts, M.J.3    Oldfield, B.J.4
  • 13
    • 33845866857 scopus 로고    scopus 로고
    • Inflammation and metabolic disorders
    • Hottamisligil G. S., (2006) Inflammation and metabolic disorders. Nature 444, 860-867.
    • (2006) Nature , vol.444 , pp. 860-867
    • Hottamisligil, G.S.1
  • 14
    • 43849098207 scopus 로고    scopus 로고
    • Effect of weight loss on some serum cytokines in human obesity: Increase in IL-10 after weight loss
    • Jung S., Park H. S., Kim K. S., et al. (2008) Effect of weight loss on some serum cytokines in human obesity: increase in IL-10 after weight loss. J. Nutr. Biochem. 19, 371-375.
    • (2008) J. Nutr. Biochem. , vol.19 , pp. 371-375
    • Jung, S.1    Park, H.S.2    Kim, K.S.3
  • 17
    • 33751231104 scopus 로고    scopus 로고
    • Interplay of TNF-alpha and IL-10 in regulating oxidative stress in isolated adult cardiac myocytes
    • Kaur K., Sharma A. K., Dhingra S., and, Singal P. K., (2006) Interplay of TNF-alpha and IL-10 in regulating oxidative stress in isolated adult cardiac myocytes. J. Mol. Cell. Cardiol. 41, 1023-1030.
    • (2006) J. Mol. Cell. Cardiol. , vol.41 , pp. 1023-1030
    • Kaur, K.1    Sharma, A.K.2    Dhingra, S.3    Singal, P.K.4
  • 18
    • 0032472826 scopus 로고    scopus 로고
    • Cocaine- and amphetamine-regulated transcript peptide immunohistochemical localization in the rat brain
    • Koylu E. O., Couceyro P. R., Lambert P. D., and, Kuhar M. J., (1998) Cocaine- and amphetamine-regulated transcript peptide immunohistochemical localization in the rat brain. J. Comp. Neurol. 391, 115-132.
    • (1998) J. Comp. Neurol. , vol.391 , pp. 115-132
    • Koylu, E.O.1    Couceyro, P.R.2    Lambert, P.D.3    Kuhar, M.J.4
  • 19
    • 0030222037 scopus 로고    scopus 로고
    • Microglia: A sensor for pathological events in the CNS
    • Kreutzberg G. W., (1996) Microglia: a sensor for pathological events in the CNS. Trends Neurosci. 19, 312-318.
    • (1996) Trends Neurosci. , vol.19 , pp. 312-318
    • Kreutzberg, G.W.1
  • 20
    • 0032492893 scopus 로고    scopus 로고
    • Hypothalamic CART is a new anorectic peptide regulated by leptin
    • Kristensen P., Judge M. E., Thim L., et al. (1998) Hypothalamic CART is a new anorectic peptide regulated by leptin. Nature 393, 72-76.
    • (1998) Nature , vol.393 , pp. 72-76
    • Kristensen, P.1    Judge, M.E.2    Thim, L.3
  • 21
    • 0027521572 scopus 로고
    • Interleukin-10-deficient mice develop chronic enterocolitis
    • Kühn R., Löhler J., Rennick D., Rajewsky K., and, Müller W., (1993) Interleukin-10-deficient mice develop chronic enterocolitis. Cell 75, 263-274.
    • (1993) Cell , vol.75 , pp. 263-274
    • Kühn, R.1    Löhler, J.2    Rennick, D.3    Rajewsky, K.4    Müller, W.5
  • 22
    • 77951622892 scopus 로고    scopus 로고
    • Leptin modulates cell morphology and cytokines release in microglia
    • Lafrance V., Inoue W., Kan B., and, Luheshi G. N., (2010) Leptin modulates cell morphology and cytokines release in microglia. Brain Behav. Immun. 24, 358-365.
    • (2010) Brain Behav. Immun. , vol.24 , pp. 358-365
    • Lafrance, V.1    Inoue, W.2    Kan, B.3    Luheshi, G.N.4
  • 23
    • 20144368901 scopus 로고    scopus 로고
    • Decreased splenic mRNA expression levels of TNF-alpha and IL-6 in diet-induced obese animals
    • Lamas O., Martínez J. A., and, Marti A., (2004) Decreased splenic mRNA expression levels of TNF-alpha and IL-6 in diet-induced obese animals. J. Physiol. Biochem. 60, 279-283.
    • (2004) J. Physiol. Biochem. , vol.60 , pp. 279-283
    • Lamas, O.1    Martínez, J.A.2    Marti, A.3
  • 24
    • 0034453953 scopus 로고    scopus 로고
    • N-acetyl-L-cysteine simultaneously increases mitogenesis and suppresses apoptosis in mitogen-stimulated B-lymphocytes from p53 haploinsufficient Tg.AC (v-Ha-ras) mice
    • Martin K. R., Kari F. W., Barrett J. C., and, French J. E., (2000) N-acetyl-L-cysteine simultaneously increases mitogenesis and suppresses apoptosis in mitogen-stimulated B-lymphocytes from p53 haploinsufficient Tg.AC (v-Ha-ras) mice. In Vitro Mol. Toxicol. 13, 237-248.
    • (2000) In Vitro Mol. Toxicol. , vol.13 , pp. 237-248
    • Martin, K.R.1    Kari, F.W.2    Barrett, J.C.3    French, J.E.4
  • 26
    • 0023391387 scopus 로고
    • Neuropeptide regulation of appetite and weight
    • Morley J. E., (1987) Neuropeptide regulation of appetite and weight. Endocr. Rev. 8, 256-287.
    • (1987) Endocr. Rev. , vol.8 , pp. 256-287
    • Morley, J.E.1
  • 27
    • 0030972558 scopus 로고    scopus 로고
    • Obesity, diabetes and functions for proopiomelanocortin-derived peptides
    • Mountjoy K. G., and, Wong J., (1997) Obesity, diabetes and functions for proopiomelanocortin-derived peptides. Mol. Cell. Endocrinol. 128, 171-177.
    • (1997) Mol. Cell. Endocrinol. , vol.128 , pp. 171-177
    • Mountjoy, K.G.1    Wong, J.2
  • 28
    • 54549096762 scopus 로고    scopus 로고
    • Mechanisms of macrophage activation in obesity-induced insulin resistance
    • Odegaard J. L., and, Chawla A., (2005) Mechanisms of macrophage activation in obesity-induced insulin resistance. Nat. Clin. Pract. Endocrinol. Metab. 4, 619-626.
    • (2005) Nat. Clin. Pract. Endocrinol. Metab. , vol.4 , pp. 619-626
    • Odegaard, J.L.1    Chawla, A.2
  • 29
    • 0023179245 scopus 로고
    • Feeding-related circadian variation in tele-methylhistamine levels of mouse and rat brains
    • Oishi R., Itoh Y., Nishibori M., and, Saeki K., (1987) Feeding-related circadian variation in tele-methylhistamine levels of mouse and rat brains. J. Neurochem. 49, 541-547.
    • (1987) J. Neurochem. , vol.49 , pp. 541-547
    • Oishi, R.1    Itoh, Y.2    Nishibori, M.3    Saeki, K.4
  • 30
    • 33847035924 scopus 로고    scopus 로고
    • Role of oxidative stress and apoptosis in cadmium induced thymic atrophy and splenomegaly in mice
    • Pathak N., and, Khandelwal S., (2007) Role of oxidative stress and apoptosis in cadmium induced thymic atrophy and splenomegaly in mice. Toxicol. Lett. 169, 95-108.
    • (2007) Toxicol. Lett. , vol.169 , pp. 95-108
    • Pathak, N.1    Khandelwal, S.2
  • 33
    • 34447339100 scopus 로고    scopus 로고
    • Leptin induces interleukin-1beta release from rat microglial cells through a caspase 1 independent mechanism
    • Pinteaux E., Inoue W., Schmidt L., Molina-Holgado F., Rothwell N. J., and, Luheshi G. N., (2007) Leptin induces interleukin-1beta release from rat microglial cells through a caspase 1 independent mechanism. J. Neurochem. 102, 826-833.
    • (2007) J. Neurochem. , vol.102 , pp. 826-833
    • Pinteaux, E.1    Inoue, W.2    Schmidt, L.3    Molina-Holgado, F.4    Rothwell, N.J.5    Luheshi, G.N.6
  • 34
    • 77956827261 scopus 로고    scopus 로고
    • IL-6 and IL-10 anti-inflammatory activity links exercise to hypothalamic insulin and leptin sensitivity through IKKbeta and ER stress inhibition
    • Ropelle E. R., Flores M. B., Cintra D. E., et al. (2010) IL-6 and IL-10 anti-inflammatory activity links exercise to hypothalamic insulin and leptin sensitivity through IKKbeta and ER stress inhibition. PLoS Biol. 8, e1000465.
    • (2010) PLoS Biol. , vol.8
    • Ropelle, E.R.1    Flores, M.B.2    Cintra, D.E.3
  • 35
    • 0023759108 scopus 로고
    • Evidence that NPY-containing neurons in the brainstem project into selected hypothalamic nuclei: Implication in feeding behavior
    • Sahu A., Kalra S. P., Crowley W. R., and, Kalra P. S., (1988) Evidence that NPY-containing neurons in the brainstem project into selected hypothalamic nuclei: implication in feeding behavior. Brain Res. 457, 376-378.
    • (1988) Brain Res. , vol.457 , pp. 376-378
    • Sahu, A.1    Kalra, S.P.2    Crowley, W.R.3    Kalra, P.S.4
  • 36
    • 0039112320 scopus 로고
    • Hunger and satiety related activity induced certain metabolites in rats
    • in (Hoebel B. G. and Novin D. eds.), Haer Institute for Electrophysiological Research, Brunswick, ME
    • Sakata T., (1982) Hunger and satiety related activity induced certain metabolites in rats, in The Neural Basis of Feeding and Reward (, Hoebel B. G., and, Novin D., eds.), pp. 339-354. Haer Institute for Electrophysiological Research, Brunswick, ME.
    • (1982) The Neural Basis of Feeding and Reward , pp. 339-354
    • Sakata, T.1
  • 37
    • 20244380014 scopus 로고    scopus 로고
    • Orexins and orexin receptors: A family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior
    • Sakurai T., Amemiya A., Ishii M., et al. (1998) Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior. Cell 92, 573-585.
    • (1998) Cell , vol.92 , pp. 573-585
    • Sakurai, T.1    Amemiya, A.2    Ishii, M.3
  • 38
    • 0035919144 scopus 로고    scopus 로고
    • Effect of LPS administration on the expression of POMC, NPY, galanin, CART and MCH mRNAs in the rat hypothalamus
    • Sergeyev V., Broberger C., and, Hökfelt T., (2001) Effect of LPS administration on the expression of POMC, NPY, galanin, CART and MCH mRNAs in the rat hypothalamus. Brain Res. Mol. Brain Res. 90, 93-100.
    • (2001) Brain Res. Mol. Brain Res. , vol.90 , pp. 93-100
    • Sergeyev, V.1    Broberger, C.2    Hökfelt, T.3
  • 39
  • 40
    • 0000555383 scopus 로고
    • Neuropeptide y injected in the paraventricular hypothalamus: A powerful stimulant of feeding behavior
    • Stanley B. G., and, Leibowitz S. F., (1985) Neuropeptide Y injected in the paraventricular hypothalamus: a powerful stimulant of feeding behavior. Proc. Natl Acad. Sci. USA 82, 3940-3943.
    • (1985) Proc. Natl Acad. Sci. USA , vol.82 , pp. 3940-3943
    • Stanley, B.G.1    Leibowitz, S.F.2
  • 41
    • 34548763920 scopus 로고    scopus 로고
    • Leptin-induced IL-6 production is mediated by leptin receptor, insulin receptor substrate-1, phosphatidylinositol 3-kinase, Akt, NF-kappaB, and p300 pathway in microglia
    • Tang C. H., Lu D. Y., Yang R. S., Tsai H. Y., Kao M. C., Fu W. M., and, Chen Y. F., (2007) Leptin-induced IL-6 production is mediated by leptin receptor, insulin receptor substrate-1, phosphatidylinositol 3-kinase, Akt, NF-kappaB, and p300 pathway in microglia. J. Immunol. 179, 1292-1302.
    • (2007) J. Immunol. , vol.179 , pp. 1292-1302
    • Tang, C.H.1    Lu, D.Y.2    Yang, R.S.3    Tsai, H.Y.4    Kao, M.C.5    Fu, W.M.6    Chen, Y.F.7
  • 42
    • 0037424283 scopus 로고    scopus 로고
    • Hypothalamic cocaine-amphetamine regulated transcript (CART) is regulated bu glucocorticoids
    • Vrang N., Larsen P. J., Tang-Christensen M., Larsen L. K., and, Kristensen P., (2003) Hypothalamic cocaine-amphetamine regulated transcript (CART) is regulated bu glucocorticoids. Brain Res. 965, 45-50.
    • (2003) Brain Res. , vol.965 , pp. 45-50
    • Vrang, N.1    Larsen, P.J.2    Tang-Christensen, M.3    Larsen, L.K.4    Kristensen, P.5
  • 43
    • 0037414418 scopus 로고    scopus 로고
    • Orexin-A-sensitive site for energy expenditure localized in the arcuate nucleus of the hypothalamus
    • Wang J., Osaka T., and, Inoue S., (2003) Orexin-A-sensitive site for energy expenditure localized in the arcuate nucleus of the hypothalamus. Brain Res. 971, 128-134.
    • (2003) Brain Res. , vol.971 , pp. 128-134
    • Wang, J.1    Osaka, T.2    Inoue, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.