Effect of weight loss on some serum cytokines in human obesity: increase in IL-10 after weight loss

Journal of Nutritional Biochemistry

Volumn 19, Issue 6, 2008, Pages 371-375

  Jung, Sun Hye ^a   Park, Hye Soon ^b   Kim, Kyung Soo ^c   Choi, Woong H ^d   Ahn, Chul Woo ^e   Kim, Bom Taeck ^a   Kim, Seon Mee ^f   Lee, Seon Yeong ^g   Ahn, Sang Mi ^a   Kim, Yun Kyung ^a   Kim, Hae Jin ^a   Kim, Dae Jung ^a   Lee, Kwan Woo ^a  

^a Ajou University School of Medicine   (South Korea)

^b University of Ulsan College of Medicine   (South Korea)

^c The Catholic University of Korea College of Medicine   (South Korea)

^d Hanyang University College of Medicine   (South Korea)

^e Yonsei University College of Medicine   (South Korea)

^f Korea University   (South Korea)

^g Inje University   (South Korea)

Author keywords

Adipocytokines (adipokines); Interleukin (IL) 10; Weight loss

Indexed keywords

ADIPONECTIN; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; INTERLEUKIN 10; INTERLEUKIN 6; LEPTIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL; RESISTIN; SIBUTRAMINE; TRIACYLGLYCEROL; TUMOR NECROSIS FACTOR ALPHA;

ADULT; AGED; ANTHROPOMETRIC PARAMETERS; ARTICLE; BODY FAT; BODY MASS; CALORIC RESTRICTION; CHOLESTEROL BLOOD LEVEL; CORRELATION ANALYSIS; EXERCISE; FEMALE; HEALTH PROGRAM; HUMAN; KOREA; MAJOR CLINICAL STUDY; MALE; OBESITY; PROTEIN BLOOD LEVEL; TRIACYLGLYCEROL BLOOD LEVEL; WAIST CIRCUMFERENCE; WAIST HIP RATIO; WEIGHT REDUCTION;

ADOLESCENT; ADULT; AGED; CALORIC RESTRICTION; CYTOKINES; FEMALE; HUMANS; INTERLEUKIN-10; MALE; MIDDLE AGED; OBESITY; WEIGHT LOSS;

EID: 43849098207     PISSN: 09552863     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jnutbio.2007.05.007     Document Type: Article

References (20)

1. Rajala M.W., and Scherer P.E. Minireview: the adipocyte - at the crossroads of energy homeostasis, inflammation, and atherosclerosis. Endocrinology 144 (2003) 3765-3773
2. Mallat Z., Heymes C., Ohan J., Faggin E., Lesèche G., and Tedgui A. Expression of interleukin-10 in advanced human atherosclerotic plaques: relation to inducible nitric oxide synthase expression and cell death. Arterioscler Thromb Vasc Biol 19 (1999) 611-616
3. Gunnet C.A., Heistad D.D., and Faraci F.M. Interleukin-10 protects nitric oxide-dependent relaxation during diabetes: role of superoxide. Diabetes 51 (2002) 1931-1937
4. Wang P., Wu P., Siegel M.I., Egan R.W., and Billah M.M. Interleukin (IL)-10 inhibits nuclear factor kappa B (NF kappa B) activation in human monocytes. IL-10 and IL-4 suppress cytokine synthesis by different mechanisms. J Biol Chem 270 (1995) 9558-9563
5. Lacraz S., Nicod L.P., Chicheportiche R., Welgus H.G., and Dayer J.M. IL-10 inhibits metalloproteinase and stimulates TIMP-1 production in human mononuclear phagocytes. J Clin Invest 96 (1995) 2304-2310
6. Lindmark E., Tenno T., Chen J., and Siegbahn A. IL-10 inhibits LPS-induced human monocyte tissue factor expression in whole blood. Br J Haematol 102 (1998) 597-604
7. Arai T., Hiromatsu K., Nishimura H., et al. Endogenous interleukin 10 prevents apoptosis in macrophages during Salmonella infection. Biochem Biophys Res Commun 213 (1995) 600-607
8. Geng Y., Shane R.B., Berencsi K., et al. Chlamydia pneumoniae inhibits apoptosis in human peripheral blood mononuclear cells through induction of IL-10. J Immunol 164 (2000) 5522-5529
9. Pinderski L.J., Fischbein M.P., Subbanagounder G., et al. Overexpression of interleukin-10 by activated T lymphocytes inhibits atherosclerosis in LDL receptor-deficient mice by altering lymphocyte and macrophage phenotypes. Circ Res 90 (2002) 1064-1071
10. Heeschen C., Dimmeler S., Hamm C.W., et al. CAPTURE Study Investigators. Serum level of the antiinflammatory cytokine interleukin-10 is an important prognostic determinant in patients with acute coronary syndromes. Circulation 107 (2003) 2109-2114
11. Fisman E.Z., Motro M., and Tenenbaum A. Cardiovascular diabetology in the core of a novel interleukins classification: the bad, the good and the aloof. Cardiovasc Diabetol 2 (2003) 11
12. Esposito K., Pontillo A., Giugliano F., et al. Association of low interleukin-10 levels with the metabolic syndrome in obese women. J Clin Endocrinol Metab 88 (2003) 1055-1058
13. Manigrasso M.R., Ferroni P., Santilli F., et al. Association between circulating adiponectin and interleukin-10 levels in android obesity: effects of weight loss. J Clin Endocrinol Metab 90 (2005) 5876-5879
14. Ugochukwu N.H., and Figgers C.L. Caloric restriction inhibits up-regulation of inflammatory cytokines and TNF-α, and activates IL-10 and haptoglobin in the plasma of streptozotocin-induced diabetic rats. J Nutr Biochem 18 (2007) 120-126
15. Wolf A.M., Wolf D., Rumpold H., Enrich B., and Tilg H. Adiponectin induces the anti-inflammatory cytokines IL-10 and IL-1RA in human leukocytes. Biochem Biophys Res Commun 323 (2004) 630-635
16. Yokota T., Oritani K., Takahashi I., et al. Adiponectin, a new member of the family of soluble defense collagens, negatively regulates the growth of myelomonocytic progenitors and the functions of macrophages. Blood 96 (2000) 1723-1732
17. Juge-Aubry C.E., Somm E., Pernin A., et al. Adipose tissue is a regulated source of interleukin-10. Cytokine 29 (2005) 270-274
18. Kopp H.P., Kopp C.W., Festa A., et al. Impact of weight loss on inflammatory proteins and their association with the insulin resistance syndrome in morbidly obese patients. Arterioscler Thromb Vasc Biol 23 (2003) 1042-1047
19. Hung Y.J., Chen Y.C., Pei D., et al. Sibutramine improves insulin sensitivity without alteration of serum adiponectin in obese subjects with type 2 diabetes. Diabet Med 22 (2005) 1024-1030
20. Berkowitz R.I., Fujioka K., Daniels S.R., et al. Effects of sibutramine treatment in obese adolescents: a randomized trial. Ann Intern Med 145 (2006) 81-90