Microfluidic tools to investigate pathologies in the blood microcirculation

International Journal of Nanotechnology

Volumn 9, Issue 3-7, 2012, Pages 529-547

  Preira, Pascal ^a   Leoni, Thomas ^a   Valignat, Marie Pierre ^a   Lellouch, Annemarie ^a   Robert, Philippe ^a   Forel, Jean Marie ^b   Papazian, Laurent ^b   Dumenil, Guillaume ^c,d   Bongrand, Pierre ^a   Théodoly, Olivier ^a  

^a AIX MARSEILLE UNIVERSITY   (France)

^b AIX MARSEILLE UNIVERSITÉ   (France)

^c UNIVERSITÉ PARIS DESCARTES   (France)

^d PARIS CARDIOVASCULAR RESEARCH CENTER   (France)

Author keywords

Cell adhesion; Cell mechanics; Cell migration; Cell transmigration; Meningitis; Microfluidics; Microvasculature; Respiratory distress syndrome

Indexed keywords

BACTERIA; BIOLOGICAL ORGANS; BIOMIMETIC PROCESSES; BLOOD; BLOOD VESSELS; CELL ADHESION; ENDOTHELIAL CELLS; MICROFLUIDICS; PATHOLOGY; RESPIRATORY MECHANICS; STIFFNESS; WALLS (STRUCTURAL PARTITIONS);

CELL MECHANICS; CELL MIGRATION; MENINGITIS; MICRO-VASCULATURE; RESPIRATORY DISTRESS SYNDROME;

MICROCIRCULATION;

EID: 84857184364     PISSN: 14757435     EISSN: None     Source Type: Journal    
DOI: 10.1504/IJNT.2012.045340     Document Type: Article

References (62)

1. Zernike, F. (1942) 'Phase contrast, a new method for the microscopic observation of transparent objects', Physica, Vol. 9, No.10, pp.974-986.
2. Nomarski, G. (1960) Interferential Polarizing Device for Study of Phase Objects, US Patent Office, 2, 924, 142.
3. Lessor, D.L., Hartman, J.S. and Gordon, R.L. (1979) 'Quantitative surface topography determination by Nomarski reflection microscopy, I. Theory', J. Opt. Soc. Am., Vol. 69, pp.357-366.
4. Helmchen, F. and Denk, W. (2005) 'Deep tissue two-photon microscopy', Nat. Methods, Vol. 2, pp.932-940. (Pubitemid 43108729)
5. Axelrod, D. (1981) 'Cell surface contacts illuminated by total internal reflection fluorescence', J. Cell Biol., Vol. 89, pp.141-145. (Pubitemid 11066139)
6. Betzig, E., Patterson, G.H., Sougrat, R., Lindwasser, O.W., Olenych, S., Bonifacino, J.S., Davidson, M.W., Lippincott-Schwartz, J. and Hess, H.F. (2006) 'Imaging intracellular fluorescent proteins at nanometer resolution', Science, Vol. 313, pp.1642-1645. (Pubitemid 44414039)
7. Looney, M.R., Thornton, E.E., Sen, D., Lamm, W.J., Glenny R.W. and Krummel, M. (2011) 'Stabilized imaging of immune surveillance in the mouse lung', Nat. Methods, Vol. 8, No.1, pp.91-96.
8. El-Ali, J., Sorger, P.K. and Jensen, K.F. (2006) 'Cells on chips', Nature, Vol. 442, pp.403-411. (Pubitemid 44264784)
9. Salieb-Beugelaar, G.B., Simone, G., Arora, A., Philippi, A. and Manz, A. (2010) 'Latest developments in microfluidic cell biology and analysis systems', Anal. Chem., Vol. 82, No. 12, pp.4848-4864.
10. Velve-Casquillas, G., Le Berre, M., Piel, M. and Tran, P.T. (2010) 'Microfluidics tools for cell biological research', Nanotoday, Vol. 5, pp.28-47.
11. Lipowsky, H.H., Kovalcheck, S. and Zweifach, B.W. (1978) 'The distribution of blood rheological parameters in the microvasculature of cat mesentery', Circ. Res., Vol. 43, No. 5, pp.738-749. (Pubitemid 9054867)
12. Yoshida, K., Ryoichi, K., Qin, W. and Doerschuk, C.M. (2006) 'Neutrophil Cytoskeletal rearrangements during Capillary Sequestration in Bacterial Pneumonia in Rats', Am. J. Respir. Crit. Care. Med., Vol. 174, pp.689-698. (Pubitemid 44395337)
13. Hotchkiss, S.R. and Karl, I.E. (2003) 'The pathophysiology and treatment of sepsis', N. Engl. J. Med., Vol. 348, No. 2, pp.138-150. (Pubitemid 36056721)
14. Hogg, J.C. (1987) 'Neutrophil kinetics and lung injury', Physiological Review, Vol. 67, No. 4, pp.1249-1295. (Pubitemid 18003172)
15. Wong, C.W., Song, C., Grimes, M.M., Fu, W.L., Dewhirst, M.W., Muschel, R.J. and Al-Mehdi, A.B. (2002) 'Intravascular location of breast cancer cells after spontaneous metastasis to the lung', Am. J. Pathol., Vol. 161, No. 3, pp.749-751.
16. Lam, W.A., Rosenbluth, M.J. and Fletcher, D.A. (2008) 'Increased leukaemia cell stiffness is associated with symptoms of leucostasis in paediatric acute lymphoblastic leukaemia', Br. J. Haematology, Vol. 142, No. 3, pp.497-501. (Pubitemid 351962188)
17. Alon, R., Aker, M., Feigelson, S., Sokolovsky-Eisenberg, M., Staunton, D.E., Cinamon, G., Grabovsky, V., Shamri, R. and Etzioni, A. (2003) 'A novel genetic leukocyte adhesion deficiency in subsecond triggering of integrin avidity by endothelial chemokines results in impaired leukocyte arrest on vascular endothelium under shear flow', Blood, Vol. 101, No. 11, pp.4437-4445. (Pubitemid 36857810)
18. Robert, P., Canault, M., Farnarier, C., Nurden, A., Grosdidier, C., Barlogis, V., Bongrand, P., Pierres, A., Chambost, H. and Alessi, M.C. (2011) 'A novel Leukocyte adhesion deficiency III variant: kindlin-3 deficiency results in integrin and non-integrin-related defects in different steps of leukocyte adhesion', J. Immunol., in press.
19. Mairey, E., Genovesio, A., Donnadieu, E., Bernard, C., Jaubert, F., Pinard, E., Seylaz, J., Olivo-Marin, J.C., Nassif, X. and Dumenil, G. (2006) 'Cerebral microcirculation shear stress levels determine Neisseria meningitides attachment sites along the blood-brain barrier', J. Exp. Med., Vol. 203, No. 8, pp.1939-1950. (Pubitemid 44188468)
20. Gross, S. and Walden, P. (2008) 'Immunosuppressive mechanisms in human tumors: Why we still cannot cure cancer', Immunol. Lett., Vol. 116, pp.7-14.
21. Van der Meer, A.D., Poot, A.A., Duits, M.H.G., Feijen, J. and Vermes, I. (2009) 'Microfluidic technology in vascular research', J. Biomed. Biotechnol., Vol. 2009, Article ID 823148, pp.1-10.
22. Nishino, N., Tanaka, H., Ogura, H., Inoue, Y., Koh, T., Kieko Fujita, B.S. and Hisashi Sugimoto, M.D. (2005) 'Serial changes in white blood cells deformability and whole blood rheology in patients with sepsis or trauma', J. Trauma, Vol. 59, No. 6, pp.1425-1431.
23. Gabriele, S., Benoliel, A.M., Bongrand, P. and Theodoly, O. (2009) 'Microfluidic investigation reveals distinct roles for actin cytoskeleton and Myosin II activity in capillary white blood cell trafficking', Biophys. J., Vol. 96, pp.4308-4318.
24. Rosenbluth, M.J., Lam, W.A. and Fletcher, D.A. (2008) 'Analyzing cell mechanics in hematologic diseases with microfluidic biophysical flow cytometry', Lab Chip, Vol. 8, No. 7, pp.1062-1070. (Pubitemid 351904828)
25. Chaw, K.C., Manimaran, M., Francis, E.H. and Swaminathan S. (2006) 'A quantitative observation and imaging of single tumor cell migration and deformation using a multi-gap microfluidic device representing the blood vessel', Microvascular Research, Vol. 72, pp.153-160. (Pubitemid 44767771)
26. Yap, B. and Kamm, R.D. (2005) 'Mechanical deformation of neutrophils into narrow channels induces pseudopod projection and changes in biochemical properties', J. Appl. Physiol., Vol. 98, pp.1930-1939. (Pubitemid 40570809)
27. Shelby, J.P., White, J., Ganesan, K., Rathod, P.K. and Chiu, D.T. (2003) 'A microfluidic model for single-cell capillary obstruction by plasmodium falciparum-infected erythrocytes', PNAS, Vol. 100, No.25, pp.14618-14622. (Pubitemid 37517939)
28. Hawkins, R.J., Piel, M., Faure-Andre, G., Lennon-Dumenil, A.M., Joanny, J.F., Prost, J. and Voituriez, R. (2009) 'Pushing off the walls: a mechanism of cell motility in confinement', Phys. Rev. Lett., Vol. 102, No. 058103, pp.1-5.
29. Jacobelli, J., Friedman, R.S., Conti, M.A., Lennon-Dumenil, A.M., Piel, M., Sorensen, C.M., Adelstein, R.S. and Krummel, M.F. (2010) 'Confinement-optimized three-dimensional T cell amoeboid motility is modulated via myosin IIA-regulated adhesions', Nat. Immunol., Vol. 11, No. 10, pp.953-961.
30. Chaw, K.C., Manimaran, M., Tay, F.E.H. and Swaminathan, S. (2006) 'Three-dimensional (3D) extra-cellular matrix coating of a microfluidic device', J. Phys.: Conference Series, Vol. 34, pp.747-751. (Pubitemid 43812514)
31. Van der Meer, A.D., Poot, A.A., Duits, M.H.G., Feijen, J. and Vermes. I. (2009) 'Microfluidic Technology in vascular research', J. Biomed. Biotechnol., Vol. 2009, ID.823148, pp.1-10.
32. Young, E.W.K. and Simmons, C.A. (2010) 'Macro-and microscale fluid flow systems for endothelial cell biology', Lab Chip, Vol. 2010, No. 10, pp.143-160.
33. Song, J.W., Gu, W., Futai, N., Warner, K.A., Nor, J.E. and Takayama, S. (2005) 'Computer-controlled microcirculatory support system for endothelial cell culture and shearing', Anal. Chem., Vol. 77, No.13, pp.3993-3399.
34. Tkachenko, E., Gutierrez, E., Ginsberg, M.H. and Groisman, A. (2009) 'An easy to assemble microfluidic perfusion device with a magnetic clamp', Lab Chip, Vol. 9, No. 8, pp.1085-1095.
35. Khan, O.F. and Sefton, M.V. (2011) 'Endothelial cell behaviour within a microfluidic mimic of the flow channels of a modular tissue engineered construct', Biomed. Microdevices, Vol. 13, No.1, pp.69-87.
36. Van der Meer, A.D., Poot, A.A., Feijen, J. and Vermes, I. (2010) 'Analyzing shear stress-induced alignment of actin filaments in endothelial cells with a microfluidic assay', Biomicrofluidics, Vol. 4, No. 1, 011103, pp.1-10.
37. Song, J.W., Cavnar, S.P., Walker, A.C., Luker, K.E., Gupta, M., Tung, Y.C., Luker, G.D. and Takayama, S. (2009) 'Microfluidic endothelium for studying the intravascular adhesion of metastatic breast cancer cells', PLOS One, Vol. 4, No. 6, p.e.5756.
38. Shao, J.B., Wu, L., Wu, J.Z., Zheng,Y.H., Zhao, H., Jin, Q.H. and Zhao, J.L. (2009) 'Integrated microfluidic chip for endothelial cells culture and analysis exposed to a pulsatile and oscillatory shear stress', Lab Chip, Vol. 9, No.21, pp.3118-3125.
39. Seok, C., Ryo, S., Peter, J.M., Chen-Rei, W., Vernella, V. and Roger, D. (2009) 'Cell migration into scaffolds under co-culture conditions in a microfluidic platform', Lab Chip, Vol. 2009, No. 9, pp.269-275.
40. Huh, D., Matthews, B.D., Mammoto, A., Montoya-Zavala, M., Yuan Hsin, H. and Ingber, D.E. (2010) 'Reconstituting organ-level lung functions on a chip', Science, Vol. 328, No. 5986, pp.1662-1668.
41. Ashbaugh, D.G., Bigelow, D.B., Petty, T.L. and Levine, B.E. (1967) 'Acute respiratory distress in adults', Lancet, Vol. 2, pp.319-323.
42. Ware, L.B. and Matthay, M.A. (2000) 'The acute respiratory distress syndrome', N. Engl. J. Med., Vol. 342, No. 18, pp.1334-1349. (Pubitemid 30408719)
43. Skoutelis, A.T., Vassilios, K., George, M.A., Kyriakos, I.K., Yannis, F.M. and Harry, P.B. (2000) 'Neutrophil deformability in patients with sepsis, septic shock, and adult respiratory distress syndrome', Crit. Care. Med., Vol. 2000, No. 28, pp.2355-2359. (Pubitemid 30604439)
44. Rosenbluth, M.J., Lam, W.A. and Fletcher, D.A. (2008) 'Analyzing cell mechanics in hematologic diseases with microfluidic biophysical flow cytometry', Lab Chip, Vol. 8, No. 7, pp.1062-1070. (Pubitemid 351904828)
45. Ibbotson, G.C., Doit, C., Kaur, J., Varinder, G., Lena, O., Todd, F. and Kubes, P. (2001) 'Functional α4-integrin: A newly identified pathway of neutrophil recruitment in critically ill septic patients', Nat. Med., Vol. 7, No. 4, pp.465-470. (Pubitemid 32298550)
46. Sion, M.L., David, F.T., Lesley, B., Susan, D.B., David, J.C., Pearson, D.J. and Kenneth, A.B. (2009) 'Plasma from patients with sepsis up-regulates the expression of CD49d and CD64 on blood neutrophils', Am. J. Respir. Cell Mol. Biol., Vol. 40, pp.724-732.
47. Xia, Y. and Whitesides, G.M. (1998) 'Soft lithography', Angew. Chem. Int. Ed., Vol. 37, pp.550-575.
48. Gabriele, S., Versaevel, M., Preira, P. and Theodoly, O. (2010) 'A simple microfluidic method to select, isolate, and manipulate single-cells in mechanical and biochemical assays', Lab Chip, Vol. 10, pp.1459-1467.
49. Tsuchiya, S., Yamabe, M., Yamaguchi, Y., Kobayashi, Y. and Konno, T. (1980) 'Establishment and characterization of a human acute monocytic leukemia cell line (THP-1)', Int. J. Cancer, Vol. 26, pp.171-176. (Pubitemid 10086416)
50. Bathe, M., Shirai, A., Doerschuk, C.M. and Kamm, R.D. (2002) 'Neutrophil transit times through pulmonary capillaries: the effects of capillary geometry and fMLP-stimulation', Biophys. J., Vol. 83, pp.1917-1933.
51. Needham, D. and Hochmuth, R.M. (1990) 'Rapid flow of passive neutrophils into a 4 microns pipette and measurement of cytoplasmic viscosity', J. Biomech. Eng., Vol. 112, No. 3, pp.269-276. (Pubitemid 20378626)
52. Finger, E.B., Puri, K.D., Alon, R., Lawrence, M.B., VonAndrian, U.H. and Springer, T.A. (1996) 'Adhesion through L-selectin requires a threshold hydrodynamic shear', Nature, Vol. 379, No. 6562, pp.266-269.
53. Sabri, S., Soler, M., Foa, C., Pierres, A., Benoliel, A. and Bongrand, P. (2000) 'Glycocalyx modulation is a physiological means of regulating cell adhesion', J. Cell Sci., Vol. 113, pp.1589-1600. (Pubitemid 30312507)
54. Harlan, J.M. and Liu. D.Y. (1992) Adhesion -Its Role in Inflammatory Diseases, W.H. Freeman & Co, New York, pp.117-150
55. Kucik, D.F., Dustin, M.L., Miller, J.M. and Brown, E.J. (1996) 'Adhesion-activating phorbol ester increases the mobility of leukocyte integrin LFA-1 in cultured lymphocytes', J. Clin. Invest., Vol. 97, pp.2139-2144. (Pubitemid 26143969)
56. Balland, M., Desprat, N., Icard, D., Féréol, S., Asnacios, A., Browaeys, J., Hénon, S. and Gallet, F. (2006) 'Power laws in microrheology experiments on living cells: comparative analysis and modeling', Phys. Rev., Vol. 74, No. .2, No. 021911.
57. Ausserre, D. and Valignat, M.P. (2006) 'Wide-field optical imaging of surface nanostructures', Nano Lett., Vol. 6, pp.1384-1388. (Pubitemid 44195315)
58. Valignat, M.P., Ducret, A., Métivier, M., Médard, N., Gabriele, S. Mignot, T. and Theodoly O. The Underwater Nanoworld on a Microscope Stage, in preparation.
59. Curtis, A.S. (1964) 'The mechanism of adhesion of cells to glass. A study by interference reflection Microscopy', J. Cell Biol., Vol. 20, pp.199-215.
60. Gingell, D. and Todd, I. (1979) 'Interference reflection microscopy. A quantitative theory for image interpretation and its application to cell-substratum separation measurement', Biophys. J., Vol. 26, pp.507-526. (Pubitemid 9205705)
61. Rädler, J. and Sackmann, E.J. (1993) 'Imaging optical thicknesses and separation distances of phospholipid vesicles at solid surfaces', J. Phys. II, Vol. 3, pp.727-748.
62. Theodoly, O., Huang, Z.H. and Valignat, M.P. (2010) 'New modeling of reflection interference contrast microscopy including polarization and numerical aperture effects: application to nanometric distance measurements and object profile reconstruction', Langmuir, Vol. 26, No. 3, pp.1940-1948.