In vivo high-resolution 3D Overhauser-Enhanced MRI in mice at 0.2T

Contrast Media and Molecular Imaging

Volumn 7, Issue 1, 2012, Pages 45-50

  Massot, Philippe ^a   Parzy, Elodie ^a   Pourtau, Line ^a   Mellet, Philippe ^a,d   Madelin, Guillaume ^b   Marque, Sylvain ^c   Franconi, Jean Michel ^a   Thiaudiere, Eric ^a  

^a CNRS University Bordeaux Segalen   (France)

^b NEW YORK UNIVERSITY MEDICAL CENTER   (United States)

^c AIX MARSEILLE UNIVERSITY   (France)

^d INSERM   (France)

Author keywords

In vivo; Mouse; Nitroxide; OMRI

Indexed keywords

FREE RADICAL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BIOLOGICAL ACTIVITY; BRAIN REGION; CONTROLLED STUDY; GLIOMA; IN VIVO STUDY; MOLECULAR IMAGING; MOUSE; NONHUMAN; NUCLEAR OVERHAUSER EFFECT; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; RAT; VOXEL BASED MORPHOMETRY;

ANIMALS; BODY TEMPERATURE; BRAIN NEOPLASMS; CELL LINE, TUMOR; CONTRAST MEDIA; CYCLIC N-OXIDES; ELECTRON SPIN RESONANCE SPECTROSCOPY; ELECTRONS; FEASIBILITY STUDIES; FREE RADICALS; GLIOMA; IMAGING, THREE-DIMENSIONAL; INJECTIONS, INTRAVENOUS; MAGNETIC RESONANCE IMAGING; MICE; MICE, NUDE; NEOPLASM TRANSPLANTATION; PROTONS; PYRROLES; RATS; TRANSPLANTATION, HETEROLOGOUS; WATER;

EID: 84857164605     PISSN: 15554309     EISSN: 15554317     Source Type: Journal    
DOI: 10.1002/cmmi.464     Document Type: Article

References (27)

1. Golman K, Ardenkjaer-Larsen JH, Petersson JS, Mansson S, Leunbach I. Molecular imaging with endogenous substances. Proc Natl Acad Sci USA 2003; 100(18): 10435-10439.
2. Golman K, Axelsson O, Johannesson H, Mansson S, Olofsson C, Petersson JS. Parahydrogen-induced polarization in imaging: subsecond (13)C angiography. Magn Reson Med 2001; 46(1): 1-5.
3. Albert MS, Cates GD, Driehuys B, Happer W, Saam B, Springer CS Jr, Wishnia A. Biological magnetic resonance imaging using laser-polarized 129Xe. Nature 1994; 370(6486): 199-201.
4. Middleton H, Black RD, Saam B, Cates GD, Cofer GP, Guenther R, Happer W, Hedlund LW, Johnson GA, Juvan K, et al. MR imaging with hyperpolarized 3He gas. Magn Reson Med 1995; 33(2): 271-275.
5. Overhauser AW. Polarization of nuclei in metals. Phys Rev 1953; 92(2): 411-415.
6. Abragam A. Overhauser effect in nonmetals. Phys Rev 1955; 98: 1729-1735.
7. Abragam A, Combrisson J, Solomon I. Polarisation nucléaire par effet Overhauser dans les solutions d'ion paramagnétiques. Compt Rend Acad Sci Paris 1957; 245: 157-160.
8. Alecci M, Lurie DJ, Nicholson I, Placidi G, Sotgiu A. Young Investigator Award presentation at the 13th Annual Meeting of the ESMRMB, September 1996, Prague. A proton-electron double-resonance imaging apparatus with simultaneous multiple electron paramagnetic resonance irradiation at 10mT. MAGMA 1996; 4(3-4): 187-193.
9. Lurie DJ, Bussel DM, Bell LH, Mallard JR. Proton-electron double resonance imaging of free radicals solutions. J Magn Reson 1988; 76: 366-370.
10. Lurie DJ, Foster MA, Yeung D, Hutchison JM. Design, construction and use of a large-sample field-cycled PEDRI imager. Phys Med Biol 1998; 43(7): 1877-1886.
11. Golman K, Leunbach I, Ardenkjaer-Larsen JH, Ehnholm GJ, Wistrand LG, Petersson JS, Jarvi A, Vahasalo S. Overhauser-enhanced MR imaging (OMRI). Acta Radiol 1998; 39(1): 10-17.
12. Krishna MC, English S, Yamada K, Yoo J, Murugesan R, Devasahayam N, Cook JA, Golman K, Ardenkjaer-Larsen JH, Subramanian S, Mitchell JB. Overhauser enhanced magnetic resonance imaging for tumor oximetry: coregistration of tumor anatomy and tissue oxygen concentration. Proc Natl Acad Sci USA 2002; 99(4): 2216-2221.
13. Grucker D. In vivo detection of injected free radicals by Overhauser effect imaging. Magn Reson Med 1990; 14(1): 140-147.
14. Golman K, Petersson JS, Ardenkjaer-Larsen JH, Leunbach I, Wistrand LG, Ehnholm G, Liu K. Dynamic in vivo oxymetry using overhauser enhanced MR imaging. J Magn Reson Imag 2000; 12(6): 929-938.
15. Li H, Deng Y, He G, Kuppusamy P, Lurie DJ, Zweier JL. Proton electron double resonance imaging of the in vivo distribution and clearance of a triaryl methyl radical in mice. Magn Reson Med 2002; 48(3): 530-534.
16. Li H, He G, Deng Y, Kuppusamy P, Zweier JL. In vivo proton electron double resonance imaging of the distribution and clearance of nitroxide radicals in mice. Magn Reson Med 2006; 55(3): 669-675.
17. Lurie DJ, Li H, Petryakov S, Zweier JL. Development of a PEDRI free-radical imager using a 0.38T clinical MRI system. Magn Reson Med 2002; 47(1): 181-186.
18. Seimenis I, Foster MA, Lurie DJ, Hutchison JM, Whiting PH, Payne S. The excretion mechanism of the spin label proxyl carboxylic acid (PCA) from the rat monitored by X-band ESR and PEDRI. Magn Reson Med 1997; 37(4): 552-558.
19. Lurie DJ, Davies GR, Foster MA, Hutchison JM. Field-cycled PEDRI imaging of free radicals with detection at 450mT. Magn Reson Imag 2005; 23(2): 175-181.
20. Khramtsov VV, Caia GL, Shet K, Kesselring E, Petryakov S, Zweier JL, Samouilov A. Variable field proton-electron double-resonance imaging: application to ph mapping of aqueous samples. J Magn Reson 2010; 202(2): 267-273.
21. Potapenko DI, Foster MA, Lurie DJ, Kirilyuk IA, Hutchison JM, Grigor'ev IA, Bagryanskaya EG, Khramtsov VV. Real-time monitoring of drug-induced changes in the stomach acidity of living rats using improved pH-sensitive nitroxides and low-field EPR techniques. J Magn Reson 2006; 182(1): 1-11.
22. Subramanian S, Matsumoto K, Mitchell JB, Krishna MC. Radio frequency continuous-wave and time-domain EPR imaging and Overhauser-enhanced magnetic resonance imaging of small animals: instrumental developments and comparison of relative merits for functional imaging. NMR Biomed 2004; 17(5): 263-294.
23. Utsumi H, Yamada K, Ichikawa K, Sakai K, Kinoshita Y, Matsumoto S, Nagai M. Simultaneous molecular imaging of redox reactions monitored by Overhauser-enhanced MRI with 14N- and 15N-labeled nitroxyl radicals. Proc Natl Acad Sci USA 2006; 103(5): 1463-1468.
24. Mellet P, Massot P, Madelin G, Marque SR, Harte E, Franconi JM, Thiaudiere E. New concepts in molecular imaging: non-invasive MRI spotting of proteolysis using an Overhauser effect switch. PLoS One 2009; 4(4): e5244.
25. Miraux S, Massot P, Ribot EJ, Franconi JM, Thiaudiere E. 3D TrueFISP imaging of mouse brain at 4.7T and 9.4T. J Magn Reson Imag 2008; 28(2): 497-503.
26. Matsumoto S, Yasui H, Batra S, Kinoshita Y, Bernardo M, Munasinghe JP, Utsumi H, Choudhuri R, Devasahayam N, Subramanian S, Mitchell JB, Krishna MC. Simultaneous imaging of tumor oxygenation and microvascular permeability using Overhauser enhanced MRI. Proc Natl Acad Sci USA 2009; 106(42): 17898.
27. Lurie DJ, Mader K. Monitoring drug delivery processes by EPR and related techniques - principles and applications. Adv Drug Deliv Rev 2005; 57(8): 1171-1190.