DNA binding protein A expression and methylation status in hepatocellular carcinoma and the adjacent tissue

International Journal of Oncology

Volumn 40, Issue 3, 2012, Pages 789-797

  Yasen, Mahmut ^a,c   Obulhasim, Gulanbar ^b,c   Kajino, Kazunori ^b   Mogushi, Kaoru ^a   Mizushima, Hiroshi ^a   Tanaka, Shinji ^a   Tanaka, Hiroshi ^a   Hino, Okio ^b   Arii, Shigeki ^a  

^a TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^b JUNTENDO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c XINJIANG MEDICAL UNIVERSITY   (China)

Author keywords

DNA binding protein A; Hepatocellular carcinoma; Prognosis; Promoter methylation

Indexed keywords

BISULFITE; MESSENGER RNA; PROTEIN A;

ADULT; ARTICLE; CHRONIC HEPATITIS; CONTROLLED STUDY; FEMALE; GENE EXPRESSION; HUMAN; HUMAN TISSUE; LIVER CARCINOGENESIS; LIVER CELL CARCINOMA; LIVER CIRRHOSIS; MAJOR CLINICAL STUDY; MALE; METHYLATION; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROGNOSIS; PROMOTER REGION; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS;

AGED; BASE SEQUENCE; CARCINOMA, HEPATOCELLULAR; CCAAT-ENHANCER-BINDING PROTEINS; CELL LINE, TUMOR; CELL TRANSFORMATION, NEOPLASTIC; CPG ISLANDS; DNA METHYLATION; FEMALE; HEAT-SHOCK PROTEINS; HEPATITIS, CHRONIC; HUMANS; LIVER CIRRHOSIS; LIVER NEOPLASMS; MALE; MIDDLE AGED; MOLECULAR SEQUENCE DATA; PROGNOSIS; PROMOTER REGIONS, GENETIC; RNA, MESSENGER;

EID: 84857159799     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo.2011.1282     Document Type: Article

References (30)

1. Farazi PA and DePinho RA: Hepatocellular carcinoma pathogenesis: from genes to environment. Nat Rev Cancer 6: 674-687, 2006. (Pubitemid 44286000)
2. But DY, Lai CL and Yuen MF: Natural history of hepatitis-related hepatocellular carcinoma. World J Gastroenterol 14: 1652-1656, 2008. (Pubitemid 351493370)
3. Tang ZY, Ye SL, Liu YK, et al: A decade's studies on metastasis of hepatocellular carcinoma. J Cancer Res Clin Oncol 130: 187-196, 2004.
4. Deuffic S, Poynard T, Buffat L and Valleron AJ: Trends in primary liver cancer. Lancet 351: 214-215, 1998.
5. El-Serag HB and Mason AC: Rising incidence of hepatocellular carcinoma in the United States. N Engl J Med 340: 745-750, 1999. (Pubitemid 29114292)
6. Chen CJ, Yu MW and Liaw YF: Epidemiological characteristics and rick factors of hepatocellular carcinoma. J Gastroenterol Hepatol 12: S294-S308, 1997.
7. Montesano R, Hainaut P and Wild CP: Hepatocellular carcinoma: from gene to public health. J Natl Cancer Inst 89: 1844-1851, 1997. (Pubitemid 28009820)
8. Thorgeirsson SS and Grisham JW: Molecular pathogenesis of human hepatocellular carcinoma. Nat Genet 31: 339-346, 2002. (Pubitemid 35154440)
9. Herman JG and Baylin SB: Gene silencing in cancer in association with promoter hypermethylation. N Engl J Med 349: 2042-2054, 2003. (Pubitemid 37448928)
10. Jones PA and Baylin SB: The fundamental role of epigenetic events in cancer. Nat Rev Genet 3: 415-428, 2002. (Pubitemid 34587077)
11. Jones PA and Baylin SB: The epigenomics of cancer. Cell 128: 683-692, 2007. (Pubitemid 46273572)
12. Dunn BK: Hypomethylation: one side of a larger picture. Ann N Y Acad Sci 983: 28-42, 2003.
13. Esteller M: Dormant hypermethylated tumor suppressor genes: questions and answers. J Pathol 205: 172-180, 2005.
14. Herath NI, Leggett BA and MacDonald GA: Review of genetic and epigenetic alterations in hepatocarcinogenesis. J Gastroenterol Hepatol 21: 15-21, 2006.
15. Esteller M: Aberrant DNA methylation as a cancer-inducing mechanism. Annu Rev Pharmacol Toxicol 45: 629-656, 2005.
16. Luczak MW and Jagodzinski PP: The role of DNA methylation in cancer development. Folia Histochem Cytobiol 44: 143-154, 2006. (Pubitemid 44131981)
17. Baylin SB and Ohm JE: Epigenetic gene silencing in cancer - a mechanism for early oncogenic pathway addiction? Nat Rev Cancer 6: 107-116, 2006. (Pubitemid 43361543)
18. Nishida N, Nagasaka T, Nishimura T, Ikai I, Boland CR and Goel A: Aberrant methylation of multiple tumor suppressor genes in aging liver, chronic hepatitis, and hepatocellular carcinoma. Hepatology 47: 908-918, 2008. (Pubitemid 351449682)
19. Shinichi K, Marie-Genevieve M and Minoru F: Characterization of the gene for dbpA, a family member of the nucleic-acid-binding proteins containing a cold shock domain. Eur J Biochem 231: 72-82, 1995.
20. Kajino K, Yamamoto T, Hayashi J, Umeda T, Takahara T and Hino O: Recombination hot spot of Hepatitis B virus genome bind to members of the HMG domain protein family and the Y box protein binding protein family, implication of these proteins in genomic instability. Intervirology 44: 311-316, 2001. (Pubitemid 34701946)
21. Arakawa Y, Kajino K, Kano S, et al: Transcription of dbpA, a Y box binding protein, is positively regulated by E2F1: implications in hepatocarcinogenesis. Biochem Biophys Res Commun 322: 297-302, 2004. (Pubitemid 39099258)
22. Mahmut Y, Kajino K, Kano S, et al: The up-regulation of Y box binding proteins (DNA binding protein A and Y-box binding protein-1) as prognostic marker of hepatocellular carcinoma. Clin Cancer Res 11: 7354-7361, 2005. (Pubitemid 41507694)
23. Hino O, Kajino K, Umeda T and Arakawa Y: Understanding the hypercarcinogenic state in chronic hepatitis: a clue to the prevention of human hepatocellular carcinoma. J Gastroenterol 37: 883-887, 2002. (Pubitemid 35423039)
24. Umeda T and Hino O: Molecular aspects of human hepatocarcinogenesis mediated by inflammation: from hypercarcinogenic state to normo- or hypocarcinogenic state. Oncology 62: 38-42, 2002. (Pubitemid 34702018)
25. Mahmut Y, Hiroshi M, Kaoru M, et al: Expression of Aurora B and alternative variant forms in hepatocellular carcinoma and adjacent tissue. Cancer Sci 100: 472-480, 2009.
26. Herman JG, Graff JR, Myöhänen S, Nelkin BD and Baylin SB: Methylation specific PCR: a novel PCR assay for methylation status of CpG islands. Proc Natl Acad Sci USA 93: 9821-9826, 1996. (Pubitemid 26296693)
27. Safe S and Abdelrahim M: Sp transcription factor family and its role in cancer. Eur J Cancer 41: 2438-2448, 2005. (Pubitemid 41540621)
28. Abdelrahim M, Smith R III, Burghardt R and Safe S: Role of Sp proteins in regulation of vascular endothelial growth factor expression and proliferation of pancreatic cancer cells. Cancer Res 64: 6740-6749, 2004. (Pubitemid 39297937)
29. Zannetti A, Del Vecchio S, Carriero MV, et al: Coordinate up-regulation of Sp1 DNA-binding activity and urokinase receptor expression in breast carcinoma. Cancer Res 60: 1546-1551, 2000. (Pubitemid 30183423)
30. Yao JC, Wang L, Wei D, et al: Association between expression of transcription factor Sp1 and increased vascular endothelial growth factor expression, advanced stage, and poor survival in patients with resected gastric cancer. Clin Cancer Res 10: 4109-4117, 2004. (Pubitemid 38812490)