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Volumn 62, Issue , 2012, Pages 105-113

HPLC method for determination of biologically active epoxy-transformers of treosulfan in human plasma: Pharmacokinetic application

Author keywords

Epoxides; Esters; Hematopoietic stem cell transplantation; Optimization; RP HPLC; Validation

Indexed keywords

2,4 DINITROPHENOL; ACETONITRILE; BENZENESULFONIC ACID DERIVATIVE; BUTADIENE DIEPOXIDE; DICHLOROMETHANE; TREOSULFAN; WATER;

EID: 84857138746     PISSN: 07317085     EISSN: 1873264X     Source Type: Journal    
DOI: 10.1016/j.jpba.2011.12.021     Document Type: Article
Times cited : (21)

References (26)
  • 1
    • 0032191382 scopus 로고    scopus 로고
    • Treosulfan as an effective second-line therapy in ovarian cancer
    • Gropp M., Meier W., Hepp H. Treosulfan as an effective second-line therapy in ovarian cancer. Gynecol. Oncol. 1998, 71:94-98.
    • (1998) Gynecol. Oncol. , vol.71 , pp. 94-98
    • Gropp, M.1    Meier, W.2    Hepp, H.3
  • 2
    • 0242329662 scopus 로고    scopus 로고
    • Metronomic oral low-dose treosulfan chemotherapy combined with cyclooxygenase-2 inhibitor in pretreated advanced melanoma: a pilot study
    • Spieth K., Kaufmann R., Gille J. Metronomic oral low-dose treosulfan chemotherapy combined with cyclooxygenase-2 inhibitor in pretreated advanced melanoma: a pilot study. Cancer Chemother. Pharmacol. 2003, 52:377-382.
    • (2003) Cancer Chemother. Pharmacol. , vol.52 , pp. 377-382
    • Spieth, K.1    Kaufmann, R.2    Gille, J.3
  • 6
    • 55949130876 scopus 로고    scopus 로고
    • Treosulphan as an alternative to busulphan for myeloablative conditioning in paediatric allogeneic transplantation
    • Cutting R., Mirelman A., Vora A. Treosulphan as an alternative to busulphan for myeloablative conditioning in paediatric allogeneic transplantation. Br. J. Haematol. 2008, 143:748-751.
    • (2008) Br. J. Haematol. , vol.143 , pp. 748-751
    • Cutting, R.1    Mirelman, A.2    Vora, A.3
  • 7
    • 34247239884 scopus 로고    scopus 로고
    • Treosulfan
    • Churchill Livingstone, Edinburgh, C. Dollery (Ed.)
    • Boobis A., Rawlins M., Thomas S., Wilkins M. Treosulfan. The Drugs 1999, T161-T162. Churchill Livingstone, Edinburgh. second ed. C. Dollery (Ed.).
    • (1999) The Drugs
    • Boobis, A.1    Rawlins, M.2    Thomas, S.3    Wilkins, M.4
  • 8
    • 0014876558 scopus 로고
    • Studies on epoxide formation from (2S,3S)-threitol 1,4-bismethanesulfonate. The preparation and biological activity of (2S,3S)-1,2-epoxy-3,4-butanediol 4-methanesulfonate
    • Feit P.W., Rastrup-Andersen N., Matagne R. Studies on epoxide formation from (2S,3S)-threitol 1,4-bismethanesulfonate. The preparation and biological activity of (2S,3S)-1,2-epoxy-3,4-butanediol 4-methanesulfonate. J. Med. Chem. 1970, 13:1173-1175.
    • (1970) J. Med. Chem. , vol.13 , pp. 1173-1175
    • Feit, P.W.1    Rastrup-Andersen, N.2    Matagne, R.3
  • 9
    • 0032943945 scopus 로고    scopus 로고
    • DNA alkylation and interstrand cross-linking by treosulfan
    • Hartley J.A., O'Hare C.C., Baumgart J. DNA alkylation and interstrand cross-linking by treosulfan. Br. J. Cancer 1999, 79:264-266.
    • (1999) Br. J. Cancer , vol.79 , pp. 264-266
    • Hartley, J.A.1    O'Hare, C.C.2    Baumgart, J.3
  • 10
    • 0007239616 scopus 로고
    • Activity of l-threitol-1,4-bismethanesulfonate on barley chromosomes in relation to chemical transformation during treatment
    • Matagne R. Activity of l-threitol-1,4-bismethanesulfonate on barley chromosomes in relation to chemical transformation during treatment. Mutat. Res. 1967, 4:621-630.
    • (1967) Mutat. Res. , vol.4 , pp. 621-630
    • Matagne, R.1
  • 11
    • 34247196139 scopus 로고    scopus 로고
    • Determination of treosulfan in plasma and urine by HPLC with refractometric detection; pharmacokinetics studies in children undergoing myeloablative treatment prior to haematopoietic stem cell transplantation
    • Główka F.K., Karaźniewicz-Łada M., Grund G., Wachowiak J. Determination of treosulfan in plasma and urine by HPLC with refractometric detection; pharmacokinetics studies in children undergoing myeloablative treatment prior to haematopoietic stem cell transplantation. J. Chromatogr. B 2007, 850:569-574.
    • (2007) J. Chromatogr. B , vol.850 , pp. 569-574
    • Główka, F.K.1    Karaźniewicz-Łada, M.2    Grund, G.3    Wachowiak, J.4
  • 13
    • 0027467032 scopus 로고
    • A simplified methodology for quantitation of butadiene metabolites. Application to the study of 1,3-butadiene metabolism by rat liver microsomes
    • Cheng X., Ruth J.A. A simplified methodology for quantitation of butadiene metabolites. Application to the study of 1,3-butadiene metabolism by rat liver microsomes. Drug Metab. Dispos. 1993, 21:121-124.
    • (1993) Drug Metab. Dispos. , vol.21 , pp. 121-124
    • Cheng, X.1    Ruth, J.A.2
  • 14
    • 0028092965 scopus 로고
    • Comparison of blood concentrations of 1,3-butadiene and butadiene epoxides in mice and rats exposed to 1,3-butadiene by inhalation
    • Himmelstein M.W., Turner M.J., Asgharian B., Bond J.A. Comparison of blood concentrations of 1,3-butadiene and butadiene epoxides in mice and rats exposed to 1,3-butadiene by inhalation. Carcinogenesis 1994, 15:1479-1486.
    • (1994) Carcinogenesis , vol.15 , pp. 1479-1486
    • Himmelstein, M.W.1    Turner, M.J.2    Asgharian, B.3    Bond, J.A.4
  • 15
    • 0028897820 scopus 로고
    • Analysis of butadiene, butadiene monoxide and butadiene dioxide in blood by gas chromatography/gas chromatography/mass spectroscopy
    • Bechtold W.E., Strunk M.R., Thornton-Manning J.R., Henderson R.F. Analysis of butadiene, butadiene monoxide and butadiene dioxide in blood by gas chromatography/gas chromatography/mass spectroscopy. Chem. Res. Toxicol. 1995, 8:182-187.
    • (1995) Chem. Res. Toxicol. , vol.8 , pp. 182-187
    • Bechtold, W.E.1    Strunk, M.R.2    Thornton-Manning, J.R.3    Henderson, R.F.4
  • 16
    • 0031568224 scopus 로고    scopus 로고
    • Oxidation of butadiene monoxide to meso- and (±)-diepoxybutane by cDNA-expressed human cytochrome P450s and by mousse, rat, and human liver microsomes: evidence for preferential hydratation of meso-diepoxybutane in rat and human liver microsomes
    • Krause J.R., Elfarra A.A. Oxidation of butadiene monoxide to meso- and (±)-diepoxybutane by cDNA-expressed human cytochrome P450s and by mousse, rat, and human liver microsomes: evidence for preferential hydratation of meso-diepoxybutane in rat and human liver microsomes. Arch. Biochem. Biophys. 1997, 337:176-184.
    • (1997) Arch. Biochem. Biophys. , vol.337 , pp. 176-184
    • Krause, J.R.1    Elfarra, A.A.2
  • 17
    • 33846609438 scopus 로고    scopus 로고
    • Determination of epoxides by high-performance liquid chromatography following derivatization with N,N-diethyldithiocarbamate
    • Dupard-Julien C.L., Kandlakunta B., Uppu R.M. Determination of epoxides by high-performance liquid chromatography following derivatization with N,N-diethyldithiocarbamate. Anal. Bioanal. Chem. 2007, 387:1027-1032.
    • (2007) Anal. Bioanal. Chem. , vol.387 , pp. 1027-1032
    • Dupard-Julien, C.L.1    Kandlakunta, B.2    Uppu, R.M.3
  • 18
    • 33947105963 scopus 로고    scopus 로고
    • Metabolism of 1,3-butadiene to toxicologically relevant metabolites in single-exposed mice and rats
    • Filser J.G., Hutzler C., Meischner V., Veereshwarayya V., Csanady G.A. Metabolism of 1,3-butadiene to toxicologically relevant metabolites in single-exposed mice and rats. Chem. Biol. Interact. 2007, 166:93-103.
    • (2007) Chem. Biol. Interact. , vol.166 , pp. 93-103
    • Filser, J.G.1    Hutzler, C.2    Meischner, V.3    Veereshwarayya, V.4    Csanady, G.A.5
  • 19
    • 33744787330 scopus 로고    scopus 로고
    • Cobalamin as an analytical tool for analysis of oxirane metabolites of 1,3-butadiene: development and validation of the method
    • Haglund J., Silvari V., Esmans E., Törnqvist M. Cobalamin as an analytical tool for analysis of oxirane metabolites of 1,3-butadiene: development and validation of the method. J. Chromatogr. A 2006, 1119:246-250.
    • (2006) J. Chromatogr. A , vol.1119 , pp. 246-250
    • Haglund, J.1    Silvari, V.2    Esmans, E.3    Törnqvist, M.4
  • 21
    • 0029116450 scopus 로고
    • Disposition of butadiene monoepoxide and butadiene diepoxide in various tissues of rats and mice following a low-level inhalation exposure to 1,3-butadiene
    • Thornton-Manning J.R., Dahl A.R., Bechtold W.E., Griffith W.C., Hederson R.F. Disposition of butadiene monoepoxide and butadiene diepoxide in various tissues of rats and mice following a low-level inhalation exposure to 1,3-butadiene. Carcinogenesis 1995, 16:1723-1731.
    • (1995) Carcinogenesis , vol.16 , pp. 1723-1731
    • Thornton-Manning, J.R.1    Dahl, A.R.2    Bechtold, W.E.3    Griffith, W.C.4    Hederson, R.F.5
  • 22
    • 0030476283 scopus 로고    scopus 로고
    • The role of hydrolysis in the detoxification of 1,2:3,4-diepoxybutane by human, rat, and mouse liver and lung in vitro
    • Boogaard P.J., Bond J.A. The role of hydrolysis in the detoxification of 1,2:3,4-diepoxybutane by human, rat, and mouse liver and lung in vitro. Toxicol. Appl. Pharmacol. 1996, 141:617-627.
    • (1996) Toxicol. Appl. Pharmacol. , vol.141 , pp. 617-627
    • Boogaard, P.J.1    Bond, J.A.2
  • 23
    • 0034952902 scopus 로고    scopus 로고
    • Electrospray ionization detection of inherently nonresponsive epoxides by peptide binding
    • Cech N.B., Krone J.R., Enke C.G. Electrospray ionization detection of inherently nonresponsive epoxides by peptide binding. Rapid Commun. Mass Spectrom. 2001, 15:1040-1044.
    • (2001) Rapid Commun. Mass Spectrom. , vol.15 , pp. 1040-1044
    • Cech, N.B.1    Krone, J.R.2    Enke, C.G.3
  • 24
    • 84873063080 scopus 로고    scopus 로고
    • EMEA Quality guidelines: validation of analytical procedures: text and methodology (ICH Q2). Available from: (last accessed 17 March
    • EMEA Quality guidelines: validation of analytical procedures: text and methodology (ICH Q2). Available from: (last accessed 17 March 2011). http://www.emea.europa.eu/pdfs/human/ich/038195en.pdf.
    • (2011)
  • 25
    • 0028950589 scopus 로고
    • Determination of residual free epoxide in polyether polyols by derivatization with diethylammonium N,N-diethyldithiocarbamate and liquid chromatography
    • van Damme F., Oomens A.C. Determination of residual free epoxide in polyether polyols by derivatization with diethylammonium N,N-diethyldithiocarbamate and liquid chromatography. J. Chromatogr. A 1995, 696:41-47.
    • (1995) J. Chromatogr. A , vol.696 , pp. 41-47
    • van Damme, F.1    Oomens, A.C.2


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