-
2
-
-
0023262639
-
Inhalation toxicity studies with 1,3-butadiene. 3. Two year toxicity/carcinogenicity study in rats
-
P.E. Owen, J.R. Glaister, I.F. Gaunt and D.H. Pullinger, Inhalation toxicity studies with 1,3-butadiene. 3. Two year toxicity/carcinogenicity study in rats. Am. J. Ind. Hyg. Assoc. J., 48 (1987) 407-413.
-
(1987)
Am. J. Ind. Hyg. Assoc. J.
, vol.48
, pp. 407-413
-
-
Owen, P.E.1
Glaister, J.R.2
Gaunt, I.F.3
Pullinger, D.H.4
-
3
-
-
0017856272
-
Mutagenicity of butadiene and butadiene monoxide
-
C. deMeester, F. Poncelet, M. Roberfroid and M. Mercier, Mutagenicity of butadiene and butadiene monoxide. Biochem. Biophys. Res. Comm., 80 (1978) 298-305.
-
(1978)
Biochem. Biophys. Res. Comm.
, vol.80
, pp. 298-305
-
-
Demeester, C.1
Poncelet, F.2
Roberfroid, M.3
Mercier, M.4
-
4
-
-
0019125048
-
Mutagenicity of butadiene toward Salmonella typhimurium
-
C. deMeester, F. Poncelet, M. Roberfroid and M. Mercier, Mutagenicity of butadiene toward Salmonella typhimurium. Toxicol. Lett., 6 (1980) 125-130.
-
(1980)
Toxicol. Lett.
, vol.6
, pp. 125-130
-
-
Demeester, C.1
Poncelet, F.2
Roberfroid, M.3
Mercier, M.4
-
5
-
-
0022534543
-
Species differences in butadiene metabolism between mice and rats evaluated by inhalation pharmacokinetics
-
R. Kreiling, R.J. Laib, J.G. Filser and H.M. Bolt, Species differences in butadiene metabolism between mice and rats evaluated by inhalation pharmacokinetics. Arch. Toxicol., 58 (1986) 235-238.
-
(1986)
Arch. Toxicol.
, vol.58
, pp. 235-238
-
-
Kreiling, R.1
Laib, R.J.2
Filser, J.G.3
Bolt, H.M.4
-
6
-
-
0022530563
-
Species differences in the disposition of inhaled butadiene
-
J.A. Bond, A.R. Dahl, R.F. Henderson, J.S. Dutcher, J.L. Mauderly and L.S. Birnbaum, Species differences in the disposition of inhaled butadiene. Toxicol. Appl. Pharmacol., 84 (1986) 617-627.
-
(1986)
Toxicol. Appl. Pharmacol.
, vol.84
, pp. 617-627
-
-
Bond, J.A.1
Dahl, A.R.2
Henderson, R.F.3
Dutcher, J.S.4
Mauderly, J.L.5
Birnbaum, L.S.6
-
7
-
-
0029066987
-
High concentrations of butadiene epoxides in livers and lungs of mice compared to rats exposed to 1,3-butadiene
-
M.W. Himmelstein, B. Asgharian and J.A. Bond, High concentrations of butadiene epoxides in livers and lungs of mice compared to rats exposed to 1,3-butadiene. Toxicol. Appl. Pharmacol., 132 (1995) 281-288.
-
(1995)
Toxicol. Appl. Pharmacol.
, vol.132
, pp. 281-288
-
-
Himmelstein, M.W.1
Asgharian, B.2
Bond, J.A.3
-
8
-
-
0028785821
-
Oxidation of 1,2-epoxy-3-butene to 1,2;3,4-diepoxybutane by cDNA-expressed human cytochromes P450 2E1 and 3A4 and human, mouse and rat liver microsomes
-
M.J. Seaton, M.H. Follansbee, and J.A. Bond, Oxidation of 1,2-epoxy-3-butene to 1,2;3,4-diepoxybutane by cDNA-expressed human cytochromes P450 2E1 and 3A4 and human, mouse and rat liver microsomes. Carcinogenesis 16 (1995) 2287-2293.
-
(1995)
Carcinogenesis
, vol.16
, pp. 2287-2293
-
-
Seaton, M.J.1
Follansbee, M.H.2
Bond, J.A.3
-
9
-
-
0027951237
-
Mutagenicity of butadiene and its epoxide metabolites: I. Mutagenic potential of 1,2-epoxybutene, 1,2;3,4-diepoxybutane and 3,4-epoxy-1,2-butanediol in cultured human lymphoblasts
-
J.E. Cochrane and T.R. Skopek, Mutagenicity of butadiene and its epoxide metabolites: I. Mutagenic potential of 1,2-epoxybutene, 1,2;3,4-diepoxybutane and 3,4-epoxy-1,2-butanediol in cultured human lymphoblasts. Carcinogenesis 15 (1994) 713-717.
-
(1994)
Carcinogenesis
, vol.15
, pp. 713-717
-
-
Cochrane, J.E.1
Skopek, T.R.2
-
10
-
-
0028026138
-
Mutagenicity of butadiene and its epoxide metabolites: II. Mutational spectra of butadiene, 1,2-epoxybutene and diepoxybutane at the hprt locus in splenic T cells from exposed B6C3F1 mice
-
J.E. Cochrane and T.R. Skopek, Mutagenicity of butadiene and its epoxide metabolites: II. Mutational spectra of butadiene, 1,2-epoxybutene and diepoxybutane at the hprt locus in splenic T cells from exposed B6C3F1 mice. Carcinogenesis 15 (1994) 719-723.
-
(1994)
Carcinogenesis
, vol.15
, pp. 719-723
-
-
Cochrane, J.E.1
Skopek, T.R.2
-
11
-
-
0021999773
-
Mutagenicity and chemical reactivity of epoxide intermediates of the isoprene metabolism and other structurally related compounds
-
P.G. Gervasi, L. Citti, M. del Monte, V. Longo and D. Benetti, Mutagenicity and chemical reactivity of epoxide intermediates of the isoprene metabolism and other structurally related compounds. Mutat. Res., 156 (1985) 77-82.
-
(1985)
Mutat. Res.
, vol.156
, pp. 77-82
-
-
Gervasi, P.G.1
Citti, L.2
Del Monte, M.3
Longo, V.4
Benetti, D.5
-
12
-
-
0026741034
-
Comparison of the biotransformation of 1,3-butadiene and its metabolite, 1,2-epoxybutene, by hepatic and pulmonary tissues from humans, rats, and mice
-
G.A. Csanády, F.P. Guengerich and J.A. Bond, Comparison of the biotransformation of 1,3-butadiene and its metabolite, 1,2-epoxybutene, by hepatic and pulmonary tissues from humans, rats, and mice. Carcinogenesis 13 (1992) 1143-1153.
-
(1992)
Carcinogenesis
, vol.13
, pp. 1143-1153
-
-
Csanády, G.A.1
Guengerich, F.P.2
Bond, J.A.3
-
13
-
-
0027102026
-
S-(2-hydroxy-3-buten-1-yl) glutathione and S-(1-hydroxy-3-buten-2-yl) glutathione are in vivo metabolites of butadiene monoxide: Detection and quantitation in bile
-
J.E. Sharer and A.A. Elfarra, S-(2-hydroxy-3-buten-1-yl) glutathione and S-(1-hydroxy-3-buten-2-yl) glutathione are in vivo metabolites of butadiene monoxide: Detection and quantitation in bile. Chem. Res. Toxicol., 5 (1992) 787-790.
-
(1992)
Chem. Res. Toxicol.
, vol.5
, pp. 787-790
-
-
Sharer, J.E.1
Elfarra, A.A.2
-
14
-
-
0029116450
-
Disposition of 1,2-epoxybutene and diepoxybutane in various tissues of rats and mice following a low-level inhalation exposure to 1,3-butadiene
-
J.R. Thornton-Manning, A.R. Dahl, W.E. Bechtold, W.C. Griffith Jr. and R. Henderson, Disposition of 1,2-epoxybutene and diepoxybutane in various tissues of rats and mice following a low-level inhalation exposure to 1,3-butadiene. Carcinogenesis 16 (1995) 1723-1731.
-
(1995)
Carcinogenesis
, vol.16
, pp. 1723-1731
-
-
Thornton-Manning, J.R.1
Dahl, A.R.2
Bechtold, W.E.3
Griffith W.C., Jr.4
Henderson, R.5
-
15
-
-
0028092965
-
Comparison of blood concentrations of 1,3-butadiene and butadiene epoxides in mice and rats exposed to 1,3-butadiene by inhalation
-
M.W. Himmelstein, M.J. Turner, B. Asgharian and J.A. Bond, Comparison of blood concentrations of 1,3-butadiene and butadiene epoxides in mice and rats exposed to 1,3-butadiene by inhalation. Carcinogenesis 15 (1994) 1479-1486.
-
(1994)
Carcinogenesis
, vol.15
, pp. 1479-1486
-
-
Himmelstein, M.W.1
Turner, M.J.2
Asgharian, B.3
Bond, J.A.4
-
16
-
-
0028897820
-
Analysis of butadiene, butadiene monoxide, and butadiene dioxide in blood by gas chromatography/gas chromatography/mass spectroscopy
-
W.E. Bechtold, M.R. Strunk, J.R. Thornton-Manning and R.F. Henderson, Analysis of butadiene, butadiene monoxide, and butadiene dioxide in blood by gas chromatography/gas chromatography/mass spectroscopy. Chem. Res. Toxicol., 8 (1995) 182-187.
-
(1995)
Chem. Res. Toxicol.
, vol.8
, pp. 182-187
-
-
Bechtold, W.E.1
Strunk, M.R.2
Thornton-Manning, J.R.3
Henderson, R.F.4
-
17
-
-
0030476283
-
The role of hydrolysis in the detoxification of 1,2;3,4-diepoxybutane by human, rat, and mouse liver and lung in vitro
-
P.J. Boogaard and J.A. Bond, The role of hydrolysis in the detoxification of 1,2;3,4-diepoxybutane by human, rat, and mouse liver and lung in vitro. Toxicol. App. Pharmacol., 141 (1996) 617-627.
-
(1996)
Toxicol. App. Pharmacol.
, vol.141
, pp. 617-627
-
-
Boogaard, P.J.1
Bond, J.A.2
-
18
-
-
0003024589
-
Guidelines for collection and analysis of pharmacokinetic data
-
in: W.E. Evans, J.J. Schentag and W.J. Jusko (Eds.)
-
W.J. Jusko, Guidelines for collection and analysis of pharmacokinetic data, in: W.E. Evans, J.J. Schentag and W.J. Jusko (Eds.) Applied Pharmacokinetics: Principles of Therapeutic Drug Monitoring, 1992, pp. 2-1-2-43.
-
(1992)
Applied Pharmacokinetics: Principles of Therapeutic Drug Monitoring
, pp. 21-243
-
-
Jusko, W.J.1
-
19
-
-
0021273567
-
The problem of choosing weights in nonlinear regression analysis of pharmacokinetic data
-
C.C. Peck, L.B. Sheiner, A.I. Nichols, The problem of choosing weights in nonlinear regression analysis of pharmacokinetic data. Drug Metab. Rev., 15 (1984) 133-148.
-
(1984)
Drug Metab. Rev.
, vol.15
, pp. 133-148
-
-
Peck, C.C.1
Sheiner, L.B.2
Nichols, A.I.3
-
23
-
-
0023221791
-
Age-dependent change in warfarin distribution volume in rats: Effect of change in extracellular water volume
-
Y. Kato, J. Hirate, K. Sakaguchi, M. Ueno and I. Horikoshi, Age-dependent change in warfarin distribution volume in rats: Effect of change in extracellular water volume. J. Pharmacobio-Dyn., 10 (1987) 330-335.
-
(1987)
J. Pharmacobio-Dyn.
, vol.10
, pp. 330-335
-
-
Kato, Y.1
Hirate, J.2
Sakaguchi, K.3
Ueno, M.4
Horikoshi, I.5
-
24
-
-
0028240755
-
Metabolic cage isolation reduces antipyrine clearance in rats
-
L.J. Brunner, J.T. Dipiro and S. Feldman, Metabolic cage isolation reduces antipyrine clearance in rats. J. Pharm. Pharmacol., 46 (1994) 581-584.
-
(1994)
J. Pharm. Pharmacol.
, vol.46
, pp. 581-584
-
-
Brunner, L.J.1
Dipiro, J.T.2
Feldman, S.3
-
26
-
-
0029842284
-
Biomonitoring of 1,3-butadiene and related compounds
-
S. Osterman-Golkar and J.A. Bond, Biomonitoring of 1,3-butadiene and related compounds. Environ. Health Perspect 104 (1996) 107-915.
-
(1996)
Environ. Health Perspect
, vol.104
, pp. 107-915
-
-
Osterman-Golkar, S.1
Bond, J.A.2
-
27
-
-
0028362118
-
In vivo metabolism of butadiene by mice and rats: A comparison of physiological model predictions and experimental data
-
M.A. Medinsky, T.L. Leavens, G.A. Csanády, M.L. Gargas and J.A. Bond, In vivo metabolism of butadiene by mice and rats: a comparison of physiological model predictions and experimental data. Carcinogenesis 15 (1994) 1329-1340.
-
(1994)
Carcinogenesis
, vol.15
, pp. 1329-1340
-
-
Medinsky, M.A.1
Leavens, T.L.2
Csanády, G.A.3
Gargas, M.L.4
Bond, J.A.5
-
28
-
-
0031425880
-
Physiologically based pharmacokinetic modeling of 1,3-butadiene, 1,2-epoxy-3-butene, and 1,2:3,4-diepoxybutane toxicokinetics in mice and rats
-
000-000.
-
L.M. Sweeney, P.M. Schlosser, M.A. Medinsky and J.A. Bond, Physiologically based pharmacokinetic modeling of 1,3-butadiene, 1,2-epoxy-3-butene, and 1,2:3,4-diepoxybutane toxicokinetics in mice and rats. Carcinogenesis 18 (1997) 000-000.
-
(1997)
Carcinogenesis
, vol.18
-
-
Sweeney, L.M.1
Schlosser, P.M.2
Medinsky, M.A.3
Bond, J.A.4
-
30
-
-
0030476283
-
The role of hydrolysis in the detoxification of 1,2:3,4-diepoxybutane by human, rat, and mouse liver and lung in vitro
-
P.J. Boogaard and J.A. Bond, The role of hydrolysis in the detoxification of 1,2:3,4-diepoxybutane by human, rat, and mouse liver and lung in vitro. Toxicol. Appl. Pharmacol., 141 (1996) 617-627.
-
(1996)
Toxicol. Appl. Pharmacol.
, vol.141
, pp. 617-627
-
-
Boogaard, P.J.1
Bond, J.A.2
-
31
-
-
0028794711
-
Synthesis and characterization of N-acetyl-L-cysteine S-conjugates of butadiene monoxide and their detection and quantitation in urine of rats and mice given butadiene monoxide
-
A.A. Elfarra, J.E. Sharer and R.J. Duescher, Synthesis and characterization of N-acetyl-L-cysteine S-conjugates of butadiene monoxide and their detection and quantitation in urine of rats and mice given butadiene monoxide. Chem. Res. Toxicol., 8 (1995) 68-76.
-
(1995)
Chem. Res. Toxicol.
, vol.8
, pp. 68-76
-
-
Elfarra, A.A.1
Sharer, J.E.2
Duescher, R.J.3
-
32
-
-
0025934841
-
Hemoglobin adducts and urinary mercapturic acids in rats as biological indicators of butadiene exposure
-
S. Osterman-Golkar, A. Kautiainen, E. Bergmark, K. Håkansson and J. Mäki-Paakkanen, Hemoglobin adducts and urinary mercapturic acids in rats as biological indicators of butadiene exposure. Chem.-Biol. Interact., 80 (1991) 291-302.
-
(1991)
Chem.-Biol. Interact.
, vol.80
, pp. 291-302
-
-
Osterman-Golkar, S.1
Kautiainen, A.2
Bergmark, E.3
Håkansson, K.4
Mäki-Paakkanen, J.5
-
33
-
-
0003738717
-
-
International Life Sciences Institute and the Risk Science Institute Working Group, ILSI RSI Working Group. Washington, D.C., 103 pp.
-
International Life Sciences Institute and the Risk Science Institute Working Group, Physiological parameter values for PBPK models. ILSI RSI Working Group. Washington, D.C., 1994, 103 pp.
-
(1994)
Physiological Parameter Values for PBPK Models
-
-
-
34
-
-
0021056672
-
Biological activation of 1,3-butadiene to vinyl oxirane by rat liver microsomes and expiration of the reactive metabolite by exposed rats
-
H.M. Bolt, G. Schmiedel, J.G. Filser, H.P. Rolzhauser, K. Lieser, D. Wistuba and V. Schurig, Biological activation of 1,3-butadiene to vinyl oxirane by rat liver microsomes and expiration of the reactive metabolite by exposed rats. Cancer Res. Clin. Oncol., 106 (1983) 112-116.
-
(1983)
Cancer Res. Clin. Oncol.
, vol.106
, pp. 112-116
-
-
Bolt, H.M.1
Schmiedel, G.2
Filser, J.G.3
Rolzhauser, H.P.4
Lieser, K.5
Wistuba, D.6
Schurig, V.7
|