Cobalamin as an analytical tool for analysis of oxirane metabolites of 1,3-butadiene: Development and validation of the method

Journal of Chromatography A

Volumn 1119, Issue 1-2, 2006, Pages 246-250

  Haglund, J ^a   Silvari, V ^a   Esmans, E ^b   Tornqvist M ^a  

^a STOCKHOLM UNIVERSITY   (Sweden)

^b UNIVERSITY OF ANTWERP   (Belgium)

Author keywords

Butadiene; Cobalamin; Diepoxybutane; In vitro metabolism

Indexed keywords

ASSAYS; BIOLOGICAL ORGANS; CHROMATOGRAPHIC ANALYSIS; METABOLITES;

COBALAMIN; DIEPOXYBUTANE; IN VITRO METABOLISM;

BUTADIENE;

1,2 EPOXYBUTENE; 1,3 BUTADIENE; ALKANE DERIVATIVE; ALKYL GROUP; BUTADIENE DIEPOXIDE; COBALAMIN; ETHYLENE OXIDE; ETHYLENE OXIDE DERIVATIVE; UNCLASSIFIED DRUG;

ACCURACY; ANALYTIC METHOD; ARTICLE; ASSAY; CONCENTRATION RESPONSE; LINEAR SYSTEM; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; METABOLITE; PRIORITY JOURNAL; PROCESS DEVELOPMENT; SENSITIVITY ANALYSIS; VALIDATION STUDY;

ANIMALS; BUTADIENES; CHROMATOGRAPHY, LIQUID; ETHYLENE OXIDE; LIVER; MASS SPECTROMETRY; MICE; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; VITAMIN B 12;

EID: 33744787330     PISSN: 00219673     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chroma.2005.11.069     Document Type: Article

References (17)

1. Csanády G.A., Guengerich F.P., and Bond J.A. Carcinogenesis 13 (1992) 1143
2. Boogard J., and Bond J. Toxicol. Appl. Pharmacol. 141 (1996) 617
3. Göthe B., Calleman C.J., Ehrenberg L., and Wachtmeister C.A. AMBIO 3 (1974) 234
4. Cech N., Krone J.R., and Enke C.G. Rapid Commun. Mass Spectrom. 15 (2001) 1040
5. Schrauzer G.N., Deutsch E., and Windgassen R.J. J. Am. Chem. Soc. 90 (1968) 2441
6. Schrauzer G.N., and Deutsch E. J. Am. Chem. Soc. 91 (1969) 3341
7. Haglund J., Magnusson A.L., Ehrenberg L., and Törnqvist M. Toxicol. Environ. Chem. 85 (2003) 81
8. Silvari V., Haglund J., Jenssen D., Golding B.T., Ehrenberg L., and Törnqvist M. Mutat. Res. 580 (2005) 91
9. Alsberg T., Minten J., Haglund J., and Törnqvist M. Rapid Commun. Mass Spectrom. 15 (2001) 2438
10. Hoffmann D., Hoffmann I., and El Bayoumi K. Chem. Res. Toxicol. 14 (2001) 767
11. Morrow L. Chem. Biol. Interact. 135-136 (2001) 137
12. U.S. Environmental Protection Agency (US EPA), National Center for Environmental Assessment, Office of Research and Development, Health Assessment of 1,3-Butadiene Washington D.C., 2002.
13. Fred C., Haglund J., Alsberg T., Rydberg P., Minten J., and Törnqvist M. J. Sep. Sci. 27 (2004) 607
14. Ehrenberg L., and Wachtmeister C.A. In: Kilbey B.J., et al. (Ed). Handbook of Mutagenicity Test Procedures vol. 36 (1984), Elsevier Science Publishers 765
15. Haglund J., Van Dongen W., Lemière F., and Esmans E.L. J. Am. Soc. Mass Spectrom. 15 (2004) 593
16. Bressolle F., Bromet-Petit M., and Audran M. J. Chromatogr. B 686 (1996) 3
17. International Committee on Harmonization Guidelines for the Photostability Testing of New Drug Substances and Products, Federal Register, 62, 1997, p. 27115.