Periplasmic delivery of biologically active human Interleukin-10 in Escherichia coli via a sec-dependent signal peptide

Journal of Molecular Microbiology and Biotechnology

Volumn 22, Issue 1, 2012, Pages 1-9

  Pöhlmann, Christoph ^a   Brandt, Manuela ^a   Mottok, Dorothea S ^a,b   Zschüttig, Anke ^a   Campbell, John W ^c   Blattner, Frederick R ^c   Frisch, David ^c   Gunzer, Florian ^a  

^a DRESDEN UNIVERSITY OF TECHNOLOGY   (Germany)

^b QIAGEN GMBH   (Germany)

^c UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

Bacterial transport system; Escherichia coli; Inflammatory bowel disease; Interleukin 10; Outer membrane protein F

Indexed keywords

DNA FRAGMENT; LIPOPOLYSACCHARIDE; OUTER MEMBRANE PROTEIN F; PECTATE LYASE; PROTEIN SECB; RECOMBINANT INTERLEUKIN 10; STAT3 PROTEIN; TUMOR NECROSIS FACTOR ALPHA;

5' UNTRANSLATED REGION; AMINO ACID SEQUENCE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BACTERIAL STRAIN; CONTROLLED STUDY; CYTOKINE RELEASE; CYTOPLASM; DIMERIZATION; DNA SYNTHESIS; ESCHERICHIA COLI; HYDROPHILICITY; HYDROPHOBICITY; MOLECULAR WEIGHT; NONHUMAN; NUCLEOTIDE SEQUENCE; PHYSICAL CHEMISTRY; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

ANIMALS; BACTERIAL OUTER MEMBRANE PROTEINS; CULTURE MEDIA; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; GENE EXPRESSION; INTERLEUKIN-10; MACROPHAGES; MICE; MOLECULAR WEIGHT; PERIPLASM; PROTEIN MULTIMERIZATION; PROTEIN SORTING SIGNALS; RECOMBINANT FUSION PROTEINS; TUMOR NECROSIS FACTOR-ALPHA;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI;

EID: 84857127594     PISSN: 14641801     EISSN: 16602412     Source Type: Journal    
DOI: 10.1159/000336043     Document Type: Article

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