메뉴 건너뛰기




Volumn 12, Issue 3, 2012, Pages 210-217

New target therapies for brain metastases from breast cancer

Author keywords

Blood brain barrier; Brain metastases; Breast cancer; Central nervous system; HER2; Lapatinib; Trastuzumab; Triple negative

Indexed keywords

ANTINEOPLASTIC AGENT; BEVACIZUMAB; BRCA1 PROTEIN; BRCA2 PROTEIN; CAPECITABINE; CARBOPLATIN; CISPLATIN; EPIDERMAL GROWTH FACTOR RECEPTOR 2; ETOPOSIDE; INIPARIB; IRINOTECAN; JNJ 28871063; LAPATINIB; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE INHIBITOR; PROTEIN TYROSINE KINASE INHIBITOR; TEMOZOLOMIDE; TRASTUZUMAB; UNCLASSIFIED DRUG; VELIPARIB;

EID: 84857127375     PISSN: 15680096     EISSN: 18735576     Source Type: Journal    
DOI: 10.2174/156800912799277548     Document Type: Article
Times cited : (6)

References (65)
  • 1
  • 2
    • 84858698969 scopus 로고    scopus 로고
    • Effect of tumor subtype on survival and the graded prognostic assessment for patients with breast cancer and brain metastases
    • 10.1016/ijrobp.2011.02.027
    • Sperduto, P. W.; Kased, N.; Roberge, D. Effect of tumor subtype on survival and the graded prognostic assessment for patients with breast cancer and brain metastases. Int. J. Radiat. Oncol. Biol. Phys. 2011. DOI: 10.1016/ijrobp.2011.02.027
    • (2011) Int. J. Radiat. Oncol. Biol. Phys
    • Sperduto, P.W.1    Kased, N.2    Roberge, D.3
  • 3
    • 77953345188 scopus 로고    scopus 로고
    • Trastuzumab treatment in patients with breast cancer and metastatic CNS disease
    • Piehkowski, T.; Zielinski, C. C. Trastuzumab treatment in patients with breast cancer and metastatic CNS disease. Ann. Oncol. 2010, 21, 917-924.
    • (2010) Ann. Oncol , vol.21 , pp. 917-924
    • Piehkowski, T.1    Zielinski, C.C.2
  • 4
    • 77957346508 scopus 로고    scopus 로고
    • Breast cancer subtypes and response to systemic treatment after whole-brain radiotherapy in patients with brain metastases
    • Niwihska, A.; Murawska, M.; Pogoda, K. Breast cancer subtypes and response to systemic treatment after whole-brain radiotherapy in patients with brain metastases. Cancer 2010,116, 4238-4247.
    • (2010) Cancer , vol.116 , pp. 4238-4247
    • Niwihska, A.1    Murawska, M.2    Pogoda, K.3
  • 5
    • 52049083921 scopus 로고    scopus 로고
    • Survival in patients with brain metastases from breast cancer: The importance of HER-2 status
    • Eichler, A. F.; Kuter, I.; Ryan, P.; Schapira, L.; Younger, J.; Henson, J. W. Survival in patients with brain metastases from breast cancer: the importance of HER-2 status. Cancer 2008, 112, 2359-2367.
    • (2008) Cancer , vol.112 , pp. 2359-2367
    • Eichler, A.F.1    Kuter, I.2    Ryan, P.3    Schapira, L.4    Younger, J.5    Henson, J.W.6
  • 6
    • 55849132481 scopus 로고    scopus 로고
    • Sites of distant recurrence and clinical outcomes in patients with metastatic triple-negative breast cancer: High incidence of central nervous system metastases
    • Lin, N. U.; Claus, E.; Sohl, J.; Razzak, A. R.; Arnaout, A.; Winer, E. P. Sites of distant recurrence and clinical outcomes in patients with metastatic triple-negative breast cancer: high incidence of central nervous system metastases. Cancer 2008,113, 2638-2645.
    • (2008) Cancer , vol.113 , pp. 2638-2645
    • Lin, N.U.1    Claus, E.2    Sohl, J.3    Razzak, A.R.4    Arnaout, A.5    Winer, E.P.6
  • 8
    • 50849089897 scopus 로고    scopus 로고
    • Clinical outcomes after a diagnosis of brain metastases in patients with estrogen- and/or human epidermal growth factor receptor 2-positive versus triple-negative breast cancer
    • Hines, S. L.; Vallow, L. A.; Tan, W. W.; McNeil, R. B.; Perez, E. A.; Jain, A. Clinical outcomes after a diagnosis of brain metastases in patients with estrogen- and/or human epidermal growth factor receptor 2-positive versus triple-negative breast cancer. Ann. Oncol. 2008,19, 1561-1565.
    • (2008) Ann. Oncol , vol.19 , pp. 1561-1565
    • Hines, S.L.1    Vallow, L.A.2    Tan, W.W.3    McNeil, R.B.4    Perez, E.A.5    Jain, A.6
  • 9
    • 77953346211 scopus 로고    scopus 로고
    • Breast cancer brain metastases: Differences in survival depending on biological subtype, RPA RTOG prognostic class and systemic treatment after whole-brain radiotherapy (WBRT)
    • Niwihska, A.; Murawska, M.; Pogoda, K. Breast cancer brain metastases: differences in survival depending on biological subtype, RPA RTOG prognostic class and systemic treatment after whole-brain radiotherapy (WBRT). Ann. Oncol. 2010, 21, 942-948.
    • (2010) Ann. Oncol , vol.21 , pp. 942-948
    • Niwihska, A.1    Murawska, M.2    Pogoda, K.3
  • 11
    • 55249119148 scopus 로고    scopus 로고
    • HER-2-positive metastatic breast cancer: Trastuzumab and beyond. Expert. Opin
    • Metro G.; Mottolese, M.; Fabi, A. HER-2-positive metastatic breast cancer: trastuzumab and beyond. Expert. Opin. Pharmacother. 2008, 9, 2583-2601.
    • (2008) Pharmacother , vol.9 , pp. 2583-2601
    • Metro, G.1    Mottolese, M.2    Fabi, A.3
  • 14
    • 34247346051 scopus 로고    scopus 로고
    • Prognostic significance of human epidermal growth factor receptor positivity for the development of brain metastasis after newly diagnosed breast cancer
    • Gabos, Z.; Sinha, R.; Hanson, J.; Chauhan, N.; Hugh, J.; Mackey, J. R. Abdulkarim, B. Prognostic significance of human epidermal growth factor receptor positivity for the development of brain metastasis after newly diagnosed breast cancer. J. Clin. Oncol. 2006, 24, 5658-5663.
    • (2006) J. Clin. Oncol , vol.24 , pp. 5658-5663
    • Gabos, Z.1    Sinha, R.2    Hanson, J.3    Chauhan, N.4    Hugh, J.5    Mackey, J.R.6    Abdulkarim, B.7
  • 16
    • 33845599378 scopus 로고    scopus 로고
    • Ratio of trastuzumab levels in serum and cerebrospinal fluid is altered in HER2-positive breast cancer patients with brain metastases and impairment of blood-brain barrier
    • Stemmler, H. J.; Schmitt, M.; Willems, A.; Bernhard, H.; Harbeck, N.; Heinemann, V. Ratio of trastuzumab levels in serum and cerebrospinal fluid is altered in HER2-positive breast cancer patients with brain metastases and impairment of blood-brain barrier. Anticancer Drugs 2007,18, 23-28.
    • (2007) Anticancer Drugs , vol.18 , pp. 23-28
    • Stemmler, H.J.1    Schmitt, M.2    Willems, A.3    Bernhard, H.4    Harbeck, N.5    Heinemann, V.6
  • 17
    • 75649093779 scopus 로고    scopus 로고
    • Disruption of the blood brain barrier by brain metastases of triple-negative and basal-type breast cancer but not HER2/neu-positive breast cancer
    • Yonemori, K; Tsuta, K; Ono, M.; Shimizu, C; Hirakawa, A.; Hasegawa, T.; Hatanaka, Y.; Narita, Y.; Shibui, S.; Fujiwara, Y. Disruption of the blood brain barrier by brain metastases of triple-negative and basal-type breast cancer but not HER2/neu-positive breast cancer. Cancer 2010,116, 302-308.
    • (2010) Cancer , vol.116 , pp. 302-308
    • Yonemori, K.1    Tsuta, K.2    Ono, M.3    Shimizu, C.4    Hirakawa, A.5    Hasegawa, T.6    Hatanaka, Y.7    Narita, Y.8    Shibui, S.9    Fujiwara, Y.10
  • 18
    • 34250174543 scopus 로고    scopus 로고
    • Brain metastases: The HER2 paradigm
    • Lin, N. U.; Winer, E. P. Brain metastases: the HER2 paradigm. Clin. Cancer Res. 2007,13, 1648-1655.
    • (2007) Clin. Cancer Res , vol.13 , pp. 1648-1655
    • Lin, N.U.1    Winer, E.P.2
  • 20
    • 33748147285 scopus 로고    scopus 로고
    • Pharmacokinetic considerations in the treatment of CNS tumours
    • Motl, S.; Zhuang, Y.; Waters, C. M.; Stewart, C. F. Pharmacokinetic considerations in the treatment of CNS tumours. Clin. Pharmacokinet. 2006, 45, 871-903.
    • (2006) Clin. Pharmacokinet , vol.45 , pp. 871-903
    • Motl, S.1    Zhuang, Y.2    Waters, C.M.3    Stewart, C.F.4
  • 21
    • 0035188978 scopus 로고    scopus 로고
    • Use of intrathecal trastuzumab in a patient with carcinomatous meningitis
    • Laufman, L. R.; Forsthoefel, K. F. Use of intrathecal trastuzumab in a patient with carcinomatous meningitis. Clin. Breast Cancer 2001, 2, 235.
    • (2001) Clin. Breast Cancer , vol.2 , pp. 235
    • Laufman, L.R.1    Forsthoefel, K.F.2
  • 22
    • 33744939239 scopus 로고    scopus 로고
    • Application of intrathecal trastuzumab (Herceptintrade mark) for treatment of meningeal carcinomatosis in HER2-overexpressing metastatic breast cancer
    • Stemmler, H. J.; Schmitt, M.; Harbeck, N.; Willems, A.; Bernhard, H; Lässig, D.; Schoenberg, S.; Heinemann, V. Application of intrathecal trastuzumab (Herceptintrade mark) for treatment of meningeal carcinomatosis in HER2-overexpressing metastatic breast cancer. Oncol. Rep. 2006,15, 1373-1377.
    • (2006) Oncol. Rep , vol.15 , pp. 1373-1377
    • Stemmler, H.J.1    Schmitt, M.2    Harbeck, N.3    Willems, A.4    Bernhard, H.5    Lässig, D.6    Schoenberg, S.7    Heinemann, V.8
  • 23
    • 33747828928 scopus 로고    scopus 로고
    • Meningeal carcinomatosis from breast cancer treated with intrathecal trastuzumab
    • Platini, C; Long, J.; Walter, S. Meningeal carcinomatosis from breast cancer treated with intrathecal trastuzumab. Lancet Oncol. 2006, 7, 778-780.
    • (2006) Lancet Oncol , vol.7 , pp. 778-780
    • Platini, C.1    Long, J.2    Walter, S.3
  • 24
    • 54949107844 scopus 로고    scopus 로고
    • High-dose intrathecal trastuzumab for leptomeningeal metastases secondary to HER-2 overexpressing breast cancer
    • Mir, O.; Ropert, S.; Alexandre, J.; Lemare, F.; Goldwasser, F. High-dose intrathecal trastuzumab for leptomeningeal metastases secondary to HER-2 overexpressing breast cancer. Ann. Oncol. 2008.19, 1978-1980.
    • (2008) Ann. Oncol , vol.19 , pp. 1978-1980
    • Mir, O.1    Ropert, S.2    Alexandre, J.3    Lemare, F.4    Goldwasser, F.5
  • 25
    • 63949084960 scopus 로고    scopus 로고
    • Extended survival of a HER-2-positive metastatic breast cancer patient with brain metastases also treated with intrathecal trastuzumab
    • Colozza, M.; Minenza, E.; Gori, S.; Fenocchio, D.; Paolucci, C.; Aristei, C.; Floridi, P. Extended survival of a HER-2-positive metastatic breast cancer patient with brain metastases also treated with intrathecal trastuzumab. Cancer Chemother. Pharmacol. 2009, 63, 1157-1159.
    • (2009) Cancer Chemother. Pharmacol , vol.63 , pp. 1157-1159
    • Colozza, M.1    Minenza, E.2    Gori, S.3    Fenocchio, D.4    Paolucci, C.5    Aristei, C.6    Floridi, P.7
  • 26
    • 3242686392 scopus 로고    scopus 로고
    • Sensitization of breast cancer cells to radiation by trastuzumab
    • Liang, K.; Lu, Y.; Jin, W.; Ang, K. K.; Milas, L.; Fan, Z. Sensitization of breast cancer cells to radiation by trastuzumab. Mol. Cancer Ther. 2003, 2, 1113-1120.
    • (2003) Mol. Cancer Ther , vol.2 , pp. 1113-1120
    • Liang, K.1    Lu, Y.2    Jin, W.3    Ang, K.K.4    Milas, L.5    Fan, Z.6
  • 29
    • 33746851261 scopus 로고    scopus 로고
    • Noninvasive localized delivery of Herceptin to the mouse brain by MRI-guided focused ultrasound-induced blood-brain barrier disruption
    • Kinoshita, M.; McDannold, N.; Jolesz, F. A.; Hynynen, K. Noninvasive localized delivery of Herceptin to the mouse brain by MRI-guided focused ultrasound-induced blood-brain barrier disruption. Proc. Natl. Acad. Sci. U. S. A. 2006, 103, 11719-11723.
    • (2006) Proc. Natl. Acad. Sci. U. S. A , vol.103 , pp. 11719-11723
    • Kinoshita, M.1    McDannold, N.2    Jolesz, F.A.3    Hynynen, K.4
  • 30
    • 61649103519 scopus 로고    scopus 로고
    • Human neural stem cells can target and deliver therapeutic genes to breast cancer brain metastases
    • Joo, K. M.; Park, I. H.; Shin, J. Y.; Jin, J.; Kang, B. G.; Kim, M. H.; Lee, S. J.; Jo, M. Y.; Kim, S. U.; Nam, D. H. Human neural stem cells can target and deliver therapeutic genes to breast cancer brain metastases. Mol. Ther. 2009, 17, 570-575.
    • (2009) Mol. Ther , vol.17 , pp. 570-575
    • Joo, K.M.1    Park, I.H.2    Shin, J.Y.3    Jin, J.4    Kang, B.G.5    Kim, M.H.6    Lee, S.J.7    Jo, M.Y.8    Kim, S.U.9    Nam, D.H.10
  • 32
    • 84901290217 scopus 로고    scopus 로고
    • FDA drug approval summary: Lapatinib in combination with capecitabine for previously treated metastatic breast cancer that overexpresses HER-2
    • Ryan, Q.; Ibrahim, A.; Cohen, M. H.; Johnson, J.; Ko, C. W.; Sridhara, R.; Justice, R.; Pazdur, R. FDA drug approval summary: lapatinib in combination with capecitabine for previously treated metastatic breast cancer that overexpresses HER-2. Oncologist 2008, 13, 1114-1119.
    • (2008) Oncologist , vol.13 , pp. 1114-1119
    • Ryan, Q.1    Ibrahim, A.2    Cohen, M.H.3    Johnson, J.4    Ko, C.W.5    Sridhara, R.6    Justice, R.7    Pazdur, R.8
  • 36
    • 77952798443 scopus 로고    scopus 로고
    • Future roles of lapatinib in erbb2-positive breast cancer: Adjuvant and neoadjuvant trials
    • Costa, S. D.; Jackisch, C.; Thomssen, C. Future roles of lapatinib in erbb2-positive breast cancer: adjuvant and neoadjuvant trials. Breast Care (Basel). 2010, 5(s1), 22-24.
    • (2010) Breast Care (Basel) , vol.5 , Issue.s1 , pp. 22-24
    • Costa, S.D.1    Jackisch, C.2    Thomssen, C.3
  • 39
    • 77949542447 scopus 로고    scopus 로고
    • Treatment of HER2-positive metastatic breast cancer with lapatinib and capecitabine in the lapatinib expanded access programme, including efficacy in brain metastases--the UK experience
    • Sutherland, S.; Ashley, S.; Miles, D.; Chan, S.; Wardley, A.; Davidson, N.; Bhatti, R.; Shehata, M.; Nouras, H.; Camburn, T.; Johnston, S.R. Treatment of HER2-positive metastatic breast cancer with lapatinib and capecitabine in the lapatinib expanded access programme, including efficacy in brain metastases--the UK experience. Br. J. Cancer 2010, 102, 995-1002.
    • (2010) Br. J. Cancer , vol.102 , pp. 995-1002
    • Sutherland, S.1    Ashley, S.2    Miles, D.3    Chan, S.4    Wardley, A.5    Davidson, N.6    Bhatti, R.7    Shehata, M.8    Nouras, H.9    Camburn, T.10    Johnston, S.R.11
  • 41
    • 33745317987 scopus 로고    scopus 로고
    • Dramatic regression of multiple brain metastases from breast cancer with Capecitabine: Another arrow at the bow?
    • Fabi, A.; Vidiri, A.; Ferretti, G.; Felici, A.; Papaldo, P.; Carlini, P.; Mirri, A.; Nuzzo, C.; Cognetti, F. Dramatic regression of multiple brain metastases from breast cancer with Capecitabine: another arrow at the bow? Cancer Invest. 2006, 24, 466-468.
    • (2006) Cancer Invest , vol.24 , pp. 466-468
    • Fabi, A.1    Vidiri, A.2    Ferretti, G.3    Felici, A.4    Papaldo, P.5    Carlini, P.6    Mirri, A.7    Nuzzo, C.8    Cognetti, F.9
  • 42
    • 35448952569 scopus 로고    scopus 로고
    • Capecitabine therapy of central nervous system metastases from breast cancer
    • Ekenel, M.; Hormigo, A. M.; Peak, S.; Deangelis, L. M.; Abrey, L. E. Capecitabine therapy of central nervous system metastases from breast cancer. J. Neurooncol. 2007, 85, 223-227.
    • (2007) J. Neurooncol , vol.85 , pp. 223-227
    • Ekenel, M.1    Hormigo, A.M.2    Peak, S.3    Deangelis, L.M.4    Abrey, L.E.5
  • 48
    • 77958465052 scopus 로고    scopus 로고
    • Bevacizumab: Current updates in treatment
    • Van Meter, M. E.; Kim, E. S. Bevacizumab: current updates in treatment. Curr. Opin. Oncol. 2010, 22, 586-591.
    • (2010) Curr. Opin. Oncol , vol.22 , pp. 586-591
    • van Meter, M.E.1    Kim, E.S.2
  • 50
    • 0035253739 scopus 로고    scopus 로고
    • Phase I safety and pharmacokinetic study of recombinant human anti-vascular endothelial growth factor in patients with advanced cancer
    • Gordon, M. S.; Margolin, K.; Talpaz, M.; Sledge, G. W.; Holmgren, E.; Benjamin, R.; Stalter S.; Shak, S.; Adelman, D. Phase I safety and pharmacokinetic study of recombinant human anti-vascular endothelial growth factor in patients with advanced cancer. J. Clin. Oncol. 2001, 19, 843-850.
    • (2001) J. Clin. Oncol , vol.19 , pp. 843-850
    • Gordon, M.S.1    Margolin, K.2    Talpaz, M.3    Sledge, G.W.4    Holmgren, E.5    Benjamin, R.6    Stalter, S.7    Shak, S.8    Adelman, D.9
  • 52
    • 63849185969 scopus 로고    scopus 로고
    • Treatment of patients excluded from Eastern Cooperative Oncology Group 4599 and AVAiL studies: Focus on brain metastasis and squamous histology
    • Morgensztern, D.; Govindan, R. Treatment of patients excluded from Eastern Cooperative Oncology Group 4599 and AVAiL studies: focus on brain metastasis and squamous histology. Clin. Lung Cancer 2008, 9(2), 57-61.
    • (2008) Clin. Lung Cancer , vol.9 , Issue.2 , pp. 57-61
    • Morgensztern, D.1    Govindan, R.2
  • 53
    • 44949173137 scopus 로고    scopus 로고
    • Systemic therapy for lung cancer brain metastases a rationale for clinical trials
    • Oh, Y.; Stewart, D. J. Systemic therapy for lung cancer brain metastases a rationale for clinical trials. Oncology (Williston Park) 2008, 22, 168-178.
    • (2008) Oncology (Williston Park) , vol.22 , pp. 168-178
    • Oh, Y.1    Stewart, D.J.2
  • 57
    • 77956657460 scopus 로고    scopus 로고
    • Poly (ADP-ribose) polymerase as a novel therapeutic target in cancer
    • Annunziata, C. M.; O'Shaugnessy, J. Poly (ADP-ribose) polymerase as a novel therapeutic target in cancer. Clin. Cancer Res. 2010, 18, 4517-4526.
    • (2010) Clin. Cancer Res , vol.18 , pp. 4517-4526
    • Annunziata, C.M.1    O'Shaugnessy, J.2
  • 58


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.