Bolus hypertonic or normal saline resuscitation in gram-negative sepsis: Systemic and regional haemodynamic effects in sheep

Critical Care and Resuscitation

Volumn 13, Issue 4, 2011, Pages 262-270

  Wan, Li ^a,b   Bellomo, Rinaldo ^a   May, Clive N ^b  

^a AUSTIN HEALTH   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

SODIUM CHLORIDE;

ANIMAL; ARTICLE; BLOOD FLOW; BLOOD PRESSURE; CROSSOVER PROCEDURE; DRUG EFFECT; FEMALE; GRAM NEGATIVE INFECTION; HEART OUTPUT; HEART RATE; HEMODYNAMICS; KIDNEY; OSMOLARITY; RESUSCITATION; SEPSIS; SHEEP; VASCULARIZATION;

ANIMALS; BLOOD PRESSURE; CARDIAC OUTPUT; CROSS-OVER STUDIES; FEMALE; GRAM-NEGATIVE BACTERIAL INFECTIONS; HEART RATE; HEMODYNAMICS; KIDNEY; OSMOLAR CONCENTRATION; REGIONAL BLOOD FLOW; RESUSCITATION; SALINE SOLUTION, HYPERTONIC; SEPSIS; SHEEP; SODIUM CHLORIDE;

EID: 84857081004     PISSN: 14412772     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (37)

1. Vincent JL, Parquier JN, Preiser JC, et al. Terminal events in the intensive care unit: review of 258 fatal cases in one year. Crit Care Med 1989; 17: 530-3.
2. Sundararajan V, Macisaac CM, Presneill JJ, et al. Epidemiology of sepsis in Victoria, Australia. Crit Care Med 2005; 33: 71-80.
3. Angus DC, Linde-Zwirble WT, Lidicker J, et al. Epidemiology of severe sepsis in the United States: analysis of incidence, outcome, and associated costs of care. Crit Care Med 2001; 29: 1303-10.
4. Morimatsu H, Singh K, Uchino S, et al. Early and exclusive use of norepinephrine in septic shock. Resuscitation 2004; 62: 249-54.
5. Briegel J, Forst H, Haller M, et al. Stress doses of hydrocortisone reverse hyperdynamic septic shock: a prospective, randomized, double-blind, single-center study. Crit Care Med 1999; 27: 723-32.
6. Martin C, Papazian L, Perrin G, et al. Norepinephrine or dopamine for the treatment of hyperdynamic septic shock? Chest 1993; 103: 1826-31.
7. Avontuur JA, Tutein Nolthenius RP, van Bodegom JW, Bruining HA. Prolonged inhibition of nitric oxide synthesis in severe septic shock: a clinical study. Crit Care Med 1998; 26: 660-7.
8. Levy B, Bollaert PE, Lucchelli JP, et al. Dobutamine improves the adequacy of gastric mucosal perfusion in epinephrine-treated septic shock. Crit Care Med 1997; 25: 1649-54.
9. Reinelt H, Radermacher P, Fischer G, et al. Effects of a dobutamineinduced increase in splanchnic blood flow on hepatic metabolic activity in patients with septic shock. Anesthesiology 1997; 86: 818-24.
10. Ruokonen E, Takala J, Kari A, et al. Regional blood flow and oxygen transport in septic shock. Crit Care Med 1993; 21: 1296-303.
11. Parker MM, Shelhamer JH, Natanson C, et al. Serial cardiovascular variables in survivors and nonsurvivors of human septic shock: heart rate as an early predictor of prognosis. Crit Care Med 1987; 15: 923-929.
12. Kasper DL, Fauci AS, Hauser SL, et al, editors. Chapter 254. Severe sepsis and septic shock. Harrison's principles of internal medicine. 16th ed. New York: McGraw-Hill Medical, 2005.
13. Kedar I, Cohen J, Jacob ET, Ravid M. Alleviation of experimental ischemic acute renal failure by dimethyl sulfoxide. Nephron 1981; 29: 55-8.
14. Schrier RW, Wang W. Acute renal failure and sepsis. N Engl J Med 2004; 351: 159-69.
15. Parrillo JE. Pathogenetic mechanisms of septic shock. N Engl J Med 1993; 328: 1471-7.
16. Bressack MA, Morton NS, Hortop J. Group B streptococcal sepsis in the piglet: effects of fluid therapy on venous return, organ edema, and organ blood flow. Circ Res 1987; 61: 659-69.
17. Practice parameters for hemodynamic support of sepsis in adult patients in sepsis. Task Force of the American College of Critical Care Medicine, Society of Critical Care Medicine. Crit Care Med 1999; 27: 639-60.
18. Rivers E, Nguyen B, Havstad S, et al. Early goal-directed therapy in the treatment of severe sepsis and septic shock. N Engl J Med 2001; 345: 1368-77.
19. Hollenberg SM, Ahrens TS, Annane D, et al. Practice parameters for hemodynamic support of sepsis in adult patients: 2004 update. Crit Care Med 2004; 32: 1928-48.
20. Garrido Adel P, Cruz RJ Jr, Poli de Figueiredo LF, Rochae Silva M. Small volume of hypertonic saline as the initial fluid replacement in experimental hypodynamic sepsis. Crit Care 2006; 10: R62.
21. Oi Y, Aneman A, Svensson M, et al. Hypertonic saline-dextran improves intestinal perfusion and survival in porcine endotoxin shock. Crit Care Med 2000; 28: 2843-50.
22. Zakaria el R, Tsakadze NL, Garrison RN. Hypertonic saline resuscitation improves intestinal microcirculation in a rat model of hemorrhagic shock. Surgery 2006; 140: 579-87.
23. Somell A, Sollevi A, Suneson A, et al. Beneficial effects of hypertonic saline/dextran on early survival in porcine endotoxin shock. Acta Anaesthesiol Scand 2005; 49: 1124-34.
24. National Health and Medical Research Council. Australian code of practice for the care and use of animals for scientific purposes. 7th ed. Canberra: NHMRC, 2004. http://www.nhmrc.gov.au/_files_ nhmrc/publications/attachments/ea16.pdf (accessed Oct 2011).
25. National Institutes of Health. Guide for the care and use of laboratory animals. Bethesda, Md: NIH, 1996. (NIH publication no. 85-23.)
26. Bednarik JA, May CN. Evaluation of a transit-time system for the chronic measurement of blood flow in conscious sheep. J Appl Physiol 1995; 78: 524-30.
27. Dean DA, Jia CX, Cabreriza SE, et al. Validation study of a new transit time ultrasonic flow probe for continuous great vessel measurements. Asaio J 1996; 42: M671-6.
28. Wan L, Bellomo R, May CN. The effect of normal saline resuscitation on vital organ blood flow in septic sheep. Intensive Care Med 2006; 32: 1238-42.
29. Di Giantomasso D, May CN, Bellomo R. Vital organ blood flow during hyperdynamic sepsis. Chest 2003; 124: 1053-9.
30. Kreimeier U, Frey L, Dentz J, et al. Hypertonic saline dextran resusciation during the initial phase of acute endotoxemia: effect on regional blood flow. Crit Care Med 1991; 19: 801-9.
31. Rahal L, Garrido AG, Cruz RJ Jr, et al. Fluid replacement with hypertonic or isotonic solutions guided by mixed venous oxygen saturation in experimental hyperdynamic sepsis. J Trauma 2009; 67: 1205-12.
32. Batista MB, Bravin AC, Lopes LM, et al. Pressor response to fluid resuscitation in endotoxic shock: involvement of vasopressin. Crit Care Med 2009; 37: 2968-72.
33. Giusti-Paiva A, Martinez MR, Bispo-da-Silva LB, et al. Vasopressin mediates the pressor effect of hypertonic saline solution in endotoxic shock. Shock 2007; 27: 416-21.
34. Hanneman L, Reinhart K, Korell R, et al. Hypertonic saline in stabilized hyperdynamic sepsis. Shock 1996; 5: 130-4.
35. Duke GJ. Renal protective agents: a review. Crit Care Resusc 1999; 1: 265-75.
36. Bellomo R, Wan L, May C. Managing septic acute renal failure: "fill and spill"? "squeeze and diurese"? or "block Bax to the max"? Crit Care Resusc 2004; 6: 12-6.
37. Maitland K, Kiguli S, Opoka RO, et al. Mortality after fluid bolus in African children with severe infection. N Engl J Med 2011; 364: 2483-95.