Functionalization with C-terminal cysteine enhances transfection efficiency of cell-penetrating peptides through dimer formation

Biochemical and Biophysical Research Communications

Volumn 418, Issue 3, 2012, Pages 469-474

  Åmand, Helene L ^a   Nordén, Bengt ^a   Fant, Kristina ^a,b  

^a CHALMERS UNIVERSITY OF TECHNOLOGY   (Sweden)

^b SP TECHNICAL RESEARCH INSTITUTE OF SWEDEN   (Sweden)

Author keywords

Cell penetrating peptides; Cysteine; Dimerization; Disulfide bond; Gene delivery; Peptiplex

Indexed keywords

CELL PENETRATING PEPTIDE; CHLOROQUINE; CYSTEINE; DIMER; NUCLEIC ACID; PENETRATIN; PLASMID DNA; PLASMID VECTOR;

ARTICLE; BINDING AFFINITY; CARBOXY TERMINAL SEQUENCE; CHELATION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CYTOTOXICITY; DIMERIZATION; DISULFIDE BOND; DNA BINDING; ENDOSOME; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; MOLECULAR STABILITY; PRIORITY JOURNAL; THERMODYNAMICS;

AMINO ACID SEQUENCE; CARRIER PROTEINS; CELL-PENETRATING PEPTIDES; CYSTEINE; DNA; HEK293 CELLS; HUMANS; MOLECULAR SEQUENCE DATA; PLASMIDS; PROTEIN MULTIMERIZATION; PROTEIN STABILITY; RNA, SMALL INTERFERING; TRANSFECTION;

MAMMALIA;

EID: 84857079353     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2012.01.041     Document Type: Article

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