Long-term treatment with ivabradine in post-myocardial infarcted rats counteracts f-channel overexpression

British Journal of Pharmacology

Volumn 165, Issue 5, 2012, Pages 1457-1466

  Suffredini, S ^a   Stillitano, F ^a   Comini, L ^b   Bouly, M ^c   Brogioni, S ^a   Ceconi, C ^d   Ferrari, R ^d   Mugelli, A ^a,e   Cerbai, E ^a,e  

^a Geriatric Department   (Italy)

^b IRCCS   (Italy)

^c IRIS   (France)

^d UNIVERSITY HOSPITAL OF FERRARA   (Italy)

^e UNIVERSITY OF FLORENCE   (Italy)

Author keywords

electrophysiological remodelling; f current; heart rate; hyperpolarization activated cyclic nucleotide gated channels; ivabradine; post MI rat

Indexed keywords

IVABRADINE; MICRORNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CARDIOVASCULAR RESPONSE; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFICACY; DRUG TARGETING; GENE; GENE FUNCTION; GENE OVEREXPRESSION; HCN2 GENE; HCN4 GENE; HEART INFARCTION; HEART LEFT VENTRICLE; HEART MUSCLE CELL; HEART RATE; HEART RIGHT VENTRICLE; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; TREATMENT DURATION; UPREGULATION;

ANIMALS; BENZAZEPINES; CYCLIC NUCLEOTIDE-GATED CATION CHANNELS; HEART ATRIA; HEART RATE; HEART VENTRICLES; ION CHANNELS; MALE; MICRORNAS; MYOCARDIAL INFARCTION; MYOCYTES, CARDIAC; POTASSIUM CHANNELS; RATS; RATS, WISTAR; VENTRICULAR REMODELING;

EID: 84857072536     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.2011.01627.x     Document Type: Article

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