Experimental models of developmental hypothyroidism

Hormone and Metabolic Research

Volumn 44, Issue 2, 2012, Pages 79-85

  Argumedo, G S ^a   Sanz, C R ^a   Olguin H J ^b  

^a INSTITUTO NACIONAL DE PEDIATRÍA   (Mexico)

^b UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO   (Mexico)

Author keywords

animal models; hypothyroidism; thyroid gland

Indexed keywords

ANTITHYROID AGENT; RADIOISOTOPE; THYROID HORMONE;

ANEMIA; BODY HEIGHT; BONE MARROW; BONE TISSUE; BRAIN DEVELOPMENT; CENTRAL NERVOUS SYSTEM; COCHLEA INJURY; COGNITIVE DEFECT; CONSTIPATION; DYSPHAGIA; DYSPNEA; EXPERIMENTAL MODEL; HEART FAILURE; HORMONE METABOLISM; HORMONE SYNTHESIS; HUMAN; HYPOPHYSIS; HYPOTHYROIDISM; INFECTION SENSITIVITY; JAUNDICE; LEARNING; LUNG ASPIRATION; MUSCLE WEAKNESS; NEUROLOGIC DISEASE; NONHUMAN; ORGANOGENESIS; PREGNANCY; PRIORITY JOURNAL; REVIEW; SKELETAL MUSCLE; SPATIAL MEMORY; THERMOREGULATION; THYROID GLAND;

ANIMALS; DISEASE MODELS, ANIMAL; HUMANS; HYPOTHYROIDISM; THYROID HORMONES;

ANIMALIA; MUS;

EID: 84857065264     PISSN: 00185043     EISSN: 14394286     Source Type: Journal    
DOI: 10.1055/s-0031-1297941     Document Type: Review

References (74)

1. Sotelo C N, Vallejo BJ E, Barba M F. Hypothyroidism. Importance of early diagnosis. Bol Cln Hosp Estado Sonora: 1993; 10 73 76
2. Ruz RM L. Relation of seric tiroglobuline with aplasia and ectopic of tiroids in extrauterin and intrauterin congenic hypothyroidism. Facultad de Medicina, UNAM, Secretaria de Salud Instituto Nacional de Pediatra Mxico: 1997
3. Larsen P R, Davies T F, Schlumberger M J, Hay I D. Thyroid physiology and diagnostic evaluation of patients with thyroid disordered. In: Larsen P R, Kronemberg H M, Melmer S, Polonsky K S. eds. Williams Textbook of Endocrinology. Philadelphia Saunders: 2003; 331 373
4. Bautista FA J, Melchor H E. Congenic hypothyroidism: results of prevalence program at Clinic Hospital of Mochis, a second levels of medical attention. Rev Especialidades Med Quirrgicas: 2003; 8 16 20
5. Lynne B C, Rose R N. Autoinmune thyroiditis and ros. Autoimmunity Rev: 2008; 7 530 537
6. Vela A M, Gamboa C S, Prez AM E, Ortiz C J, Gonzlez CR C, Ortega V V. Epidemiology of congenic hypothyroidism in Mexico. Salud Pblica Mxico: 2004; 46 141 148
7. Marrero G N, Rodrguez F C. Congenic hypothyroidism: History and impact of screening. Rev Biomed: 2000; 11 283 292
8. Barrn U C, Prez P E. Current concepts in congenic hypothyroidism. Bol Med Hosp Inf Mex: 1996; 53 264 268
9. Ridaura S C, Lopez C E. Mortal caused by hypothyroidism based on necropsy studies. Gac Med Mex: 1995; 131 141 146
10. Snchez P C, Calzada R, Ruiz L, Altamirano N, Mndez I, Vela A M, Gamboa C S, Mandujano M. Congenic hypothyroidism: Clinic symptoms in children lower than 15 week old after positive screening. Rev Mex Pediatr: 2006; 73 272 279
11. Marfella R, Ferraraccio F, Rizzo M R, Portoghese M, Barbieri M, Basilio C, Nersita R, Siniscalchi L I, Sasso F C, Ambrosino I, Siniscalchi M, Maresca L, Sardu C, Amato G, Paolisso G, Carella C. Innate immune activity in plaque of patients with untreated and l -thyroxine-treated subclinical hypothyroidism. Endocrine Res: 2011; 96 10 15
12. Pelps S M, Rand A S, Ryan M J. A cognitive framework for mate choice and species recognition. Am Nat: 2006; 167 28 42 (Pubitemid 43039424)
13. Tsujio M, Yoshioka K, Satoh M, Watahiki Y, Mutoh K. Skin morphology of thyroidectomized rats. Vet Pathol: 2008; 45 505 511
14. Chen K, Carey L C, Valego N K, Rose J C. Thyroid hormone replacement normalizes renal renin and angiotensin receptor expression in thyroidectomized fetal sheep. Am J Physiol Regul Integr Comp Physiol: 2007; 293 701 706
15. Zimmermann E, Ribas FM J, Malafaia O, Marcodes RPC A, Nunes NP A, Stieven F E, Przysiezny P E. Tracheal suture in rats with hypothyroidism. Wound healing study. Act Cir Bras: 2009; 24 282 289
16. 131I-induced maternal hypothyroidism on the development of rat embryos. Exp Toxicol Pathol: 1999; 51 223 227
17. 131I-Induced changes in rat thyroid gland function. Braz J Med Biol Res: 2007; 40 1087 1094 (Pubitemid 47232863)
18. Usenko S V, Lepekhin A E, Lyzogubov V, Kornilovska I, Apostolov O E, Tytarenko G R, Witt M. The influence of maternal hypothyroidism and radioactive iodine on rat embryonal development: thyroid C-cells. Anatomical Record: 1999; 256 7 13 (Pubitemid 29402661)
19. 131I in FRTL 5 thyroid cells. Endocrinology: 2011; 152 1130 1135
20. MacLanahan E D, Andersen M E, Fisher J W. A biologically based dose response model for dietary iodide and the hypothalamic pituitary thyroid axis in the adult rat: evaluation of iodine deficiency. Toxicol Sci: 2008; 102 241 253 (Pubitemid 351404896)
21. Wijk N. Rijintjes Heijning BJ M. Perinatal and chronic hypothyroidism impair behavioural development in male and female rats. Experimental Physiol: 2009; 93 1199 1209
22. Sudari S B, Venu L, Sunita Y, Raghunath M. Chronic maternal dietary iodine deficiency but not thiocyanate feeding affects maternal reproduction and postnatal performance of the rat. Indian J Exp Biol: 2007; 45 603 609
23. Kawada J, Mino H, Nishida M, Yoshimura Y. An Appropriate model for congenital hypothyroidism in the rat induced by neonatal treatment with propylthiouracil and surgical thyroidectomy: Studies on learning ability and biochemical parameters. Neuroendocrinology: 1988; 47 424 430
24. Gilbert M E. Alterations in synaptic transmission and plasticity in area CA1 of adult hippocampus following developmental hypothyroidism. Dev Brain Res: 2004; 148 11 18 (Pubitemid 38147800)
25. 2 implications for the mechanism of action of methimazole-based antithyroid drugs. J Med Chem: 2008; 51 4050 4053 (Pubitemid 351956532)
26. Hasebe M, Matsumoto I, Imagawa T, Uehara M. Effects of anti-thyroid drug, methimazole, administration to rat dams on the cerebellar cortex development in their pups. Int J Dev Neurosc: 2008; 26 409 414
27. Bruce A B, Hongmei L, Robin L R. Effect of methylimidazole-induced hypothyroidism in a model of low retinal neovascular incidence. Invest Oftalmol Visual Sci: 2004; 45 919 921
28. Moriyama K, Tagami T, Usui T, Naruse M, Nambu T, Hataya Y. Antithyroid drugs inhibit thyroid hormone receptor mediated transcription. J Clin Endocrinol Metabol: 2007; 92 1066 1072 (Pubitemid 46465684)
29. Amendola E, Luca P, Macchia P E, Terracciano D, Rosica A, Chiapetta G, Kimura S. A mouse model demonstrates a multigenic of congenital hypothyroidism. Endocrinology: 2005; 146 5038 5047 (Pubitemid 41655945)
30. Johnson K R, Marden C C, Ward B P, Gagnon H L, Bronson T R, Donahue R L. Congenital hypothyroidism dwarfism, and hearing impairment caused by a missense mutation in the mouse dual oxidase 2 gene, Duox2. Mol Endocrinol: 2007; 21 1593 1602 (Pubitemid 47001084)
31. dw 1 mutants. J Neurosci: 2009; 29 1212 1223
32. Madeira M D, Sousa N, Lima AM T, Calheiros F, Cadete L, Barbosa MM P. Selective vulnerability of the hippocampal pyramidal neurons to hypothyroidism in male and female rats. J Comp Neurol: 1992; 322 501 518
33. Martnez GJ R, Pedraza P, Santacana M, Escobar R F, Morreale E G, Ruiz M A. Early effects of iodine deficiency on radial glial cells of the hippocampus of the rat fetus. J Clin Invest: 1997; 99 2701 2709 (Pubitemid 27259817)
34. Opazo M C, Gianini A, Pancetti G, Azkcona G, Alarcn L, Lizana R. Maternal hypothyroxinemia impairs spatial learning and synaptic nature and function in the offspring. Endocrinology: 2008; 149 5097 5106
35. Vara H, Martnez B, Santos A, Colino A. Thyroid hormone regulates neurotransmitter release in neonatal rat hippocampus. Neuroscience: 2002; 110 19 28 (Pubitemid 34214756)
36. Vara H, Muoz C, Colino A. Age dependent alterations of long term synaptic plasticity in thyroid deficient rats. Hippocampus: 2003; 13 816 825
37. Farahvar A, Meisami P D. Novel two-dimensional morphometric maps and quantitative analysis reveal marked growth and structural recovery of the rat hippocampal regions from early hypothyroid retardation. Exp Neurol: 2007; 204 541 555 (Pubitemid 46497043)
38. Song L, McGee J, Walsh E J. The influence of thyroid hormone deficiency on the development of cochlear nonlinearities. J Assoc Res Otolaryngol: 2008; 9 464 476
39. Barradas C P, Vieira S R, Freitas S M. Selective effect of hypothyroidism on expression of myelin markers during development. J Neurosc Res: 2001; 66 254 261
40. Ferreira A A, Pereira MJ S, Manhaes A C, Barradas P C. Ultraestructural identification of oligodendrocyte/myelin proteins in corpus callosum of hypothyroid animals. Int J Dev Neurosc: 2007; 25 87 94 (Pubitemid 46282406)
41. Goodman J H, Gilbert M E. Modest thyroid hormone insufficiency during development induces a cellular malformation in the corpus callosum: a model of cortical dysplasia. Endocrinology: 2007; 148 2593 2597 (Pubitemid 46984780)
42. Crofton K M. Developmental disruption of thyroid hormone: correlations with hearing dysfunction in rats. Risk Anal: 2004; 24 1665 1671 (Pubitemid 40076085)
43. Ciosek J, Drobnik J. Vasopressin and oxytocin release and the thyroid function. J Physiol Pharmacol: 2004; 55 423 441 (Pubitemid 38901973)
44. Ganji F, Behzadi G. Posnatal development of masseteric motoneurons in congenital hypothyroid rats. Brain Res: 2007; 1129 81 88 (Pubitemid 46048767)
45. Lechan M R, Fekete C. Role of thyroid hormone deiodination in the hypothalamus. Thyroid: 2005; 15 883 897 (Pubitemid 41339267)
46. Sui L, Anderson W L, Gilbert M E. Impairment in short term but enhanced long term synaptic potentiation and ERK activation in adult hippocampal area CA1 following developmental thyroid hormone insufficiency. Toxicol Sci: 2005; 85 647 656 (Pubitemid 40614294)
47. Darbra S, Balada F, Mart CM A, Garau A. Perinatal hypothyroidism effects on step-through passive avoidance task in rats. Physiol Behav: 2004; 82 497 501 (Pubitemid 38981638)
48. Akaike M, Kato N, Ohno H, Kobayashi T. Hyperactivity and spatial maze learning impairment of adult rats with temporary neonatal hypothyroidism. Neurotoxicol Teratol: 1991; 13 317 322
49. Negishi T, Kawasaki K, Segkiguchi S, Ishii Y, Kyuwa Y, Yoshikawa Y. Attention deficit and hyperactive neurobehavioural characteristics induced by perinatal hypothyroidism in rats. Behav Brain Res: 2005; 159 323 331 (Pubitemid 40462508)
50. Darbra S, Garau A, Balada F, Sala J, Mart CM A. Perinatal hypothyroidism effects on neuromotor competence, novelty-directed exploratory and anxiety-related behaviour and learning in rats. Behav Brain Res: 2003; 143 209 215 (Pubitemid 36937166)
51. Reid E R, Kim M E, Page D, Mara M S, Hare E. Thyroxine replacement in an animal model of congenital hypothyroidism. Physiol Behav: 2007; 91 299 303 (Pubitemid 46770810)
52. Zhang L, Blomgren K, Kuhn G H, Cooper KM C. Effects of postnatal thyroid hormone deficiency on neurogenesis in the juvenile and adult rat. Neurobiol Dis: 2009; 34 366 374
53. Sapronov S N, Fetova O Y. The effects of l -tryptophan on conditioned reflex learning and behavior in rats with experimental pathology of the thyroid gland. Neurosci Behav Physiol: 2002; 32 237 241
54. Liu Y, Redetzke A R, Said S, Pottala V J, Moreale E G, Gerdes M A. Serum thyroid hormone levels may not accurately reflect thyroid tissue levels and cardiac function in mild hypothyroidism. Am J Physiol Heart Cir Physiol: 2008; 294 37 43
55. Graham P A, Refsal K R, Nachreiner R F. Etiopathologic findings of canine hypothyroidism. Vet Clin North Am Small Anim Pract: 2007; 37 617 631 (Pubitemid 47019517)
56. Cokkinos D V, Pantos C. Tyroid hormones and their action on the myocardium. Bull Acad Natl Med: 2009; 193 327 336
57. Olivares L E, Marassi P M, Fortunato S R, da Silva CM A, Costa SH R, Arajo G I. Thyroid function disturbance and tipe 3 iodothyronine deiodinase induction after myocardial infarction in rats a time course study. Endocrinology: 2007; 148 4786 4792
58. Drobnik J, Ciosek J, Slotwinska D, Stempniak B, Zukowska D, Marczynski A. Experimental hypothyroidism increase content of collagen and glycosaminoglycans in the heart. J Physiol Parmacol: 2009; 60 57 62
59. Yildirim M K, Bagcivan I, Sarac B, Kilicarslan H, Yildirim S, Kaya T. Effect of hypothyroidism on the purinergic responses of corpus cavernosal smooth muscle in rabbits. Int Urol Nephrol: 2008; 40 691 699
60. Alturfan A A, Zengin E, Dariyerli N, Alturfan E E, Gumustas M K, Aytac E. Investigation of zinc and copper level in methimazole-induced hypotiroidism: relation with the oxidant-antioxidant status. Folia Biol (Praha): 2007; 53 183 188 (Pubitemid 47559235)
61. Gomes G M, Moreira S C, Ribeiro CA F, Ocarina N M, Moro L, Vasconcelos C A. Apoptosis, proliferation and spleen histomorphometry of adult female rats with thyroid and ovarian hypofunction. Arquivos Brasileiros Endocrinol Metabol: 2008; 52 1031 1038
62. Virdis A, Colucci R, Fornai M, Polini A, Daghini E, Duranti E. Inducible nitric oxide synthase is involved in endothelial dysfunction of mesenteric small arteries from hypothyroid rats. Endocrinology: 2009; 150 1033 1042
63. Cameron D L, Crocker A D. The hypothyroid rat as a model of increased to dopamine receptor agonists. Pharmacol Biochem Behav: 1990; 37 627 632
64. Conti M I, Martnez M P, Olivera M I, Bozzini C, Mandalunis P, Bozzini C E, Alippi R M. Biomechanical performance of diaphyseal shafts and bone tissue of femurs from hypothyroid rats. Endocrine: 2009; 36 291 298
65. Montanelli L, Tonacchera M. Genetics and phenomics of hypothyroidism and thyroid dys-and agenesis due to PAX 8 and TTF-1 mutations. Mol Cel Endocrinol: 2010; 322 64 71
66. Peppa M, Koliaki C, Nikolopoulos P, Sotirios A. Skeletal muscle insulin resistance in endocrine disease. J Biomed Biothecnol: 2010; 20 527 550
67. Hashimoto K, Cohen N R, Yamada M, Markan R K, Monden T, Satoh T, Mori M, Wondisford E F. Cross-talk between thyroid hormone receptor and liver X receptor regulatory pathways is revealed in a thyroid hormone resistance mouse model. J Biol Chem: 2006; 281 295 302 (Pubitemid 43671189)
68. Woodmansee W W, Kerr M J, Tucker A E, Mitchell R J, Haakinson J D, Gordon F D. The proliferative status thyrotropes is dependent on modulation of specific cell cycle regulators by thyroid hormone. Endocrinology: 2006; 147 272 282 (Pubitemid 43004281)
69. Maralcan G, Erkol H, Erkol Z, Yanar F, Plevin R. The effects of low thyroid hormone levels on the formation of stress gastritis: an experimental study on the rats. Turkish J Trauma Emerg Surg: 2008; 14 96 102 (Pubitemid 351507120)
70. Feitosa D S, Marques M R, Casat M Z, Sallum E A, Nociti F H, Toledo S. The influence of thyroid hormones on periodontitis related bone loss and tooth-supporting alveolar bone: a histological study in rats. J Periodontal Res: 2009; 44 472 478
71. Zoeller R T, Rovett J. Timing of thyroid hormone action in the developing brain: clinical observations and experimental findings. J Neoroendocrinol: 2004; 16 809 818 (Pubitemid 39489993)
72. Caturegli P, Kimura H. A non classical model of autoinmune hypothyroidism. Thyroid: 2010; 20 3 5
73. Green L W. Induction of a coupling defect in rats during in hibition of tyrosine dehalogenase. Endocrinology: 1976; 98 10 19
74. Berbel P, Navarro D, Aus E, Varea E, Rodrguez A E, Ballesta J J, Salinas M. Role of late maternal thyroid hormones in cerebral cortex development: an experimental model for human prematurity. Cerebral Cortex: 2010; 20 1462 1475