In vitro evaluation of cytotoxic and inflammatory properties of silica nanoparticles of different sizes in murine RAW 264.7 macrophages

Journal of Nanoparticle Research

Volumn 13, Issue 12, 2011, Pages 6775-6787

  Park, Margriet V D Z ^a,b   Lynch, Iseult ^c   Ramírez García, Sonia ^c   Dawson, Kenneth A ^c   De La Fonteyne, Liset ^a   Gremmer, Eric ^a   Slob, Wout ^a   Briedé, Jacob J ^b   Elsaesser, Andreas ^d   Howard, C Vyvyan ^d   Van Loveren, Henk ^a,b   De Jong, Wim H ^a  

^a NATIONAL INSTITUTE FOR PUBLIC HEALTH AND THE ENVIRONMENT   (Netherlands)

^b MAASTRICHT UNIVERSITY   (Netherlands)

^c UNIVERSITY COLLEGE DUBLIN   (Ireland)

^d UNIVERSITY OF ULSTER   (United Kingdom)

Author keywords

Cytokines; Cytotoxicity; Environmental and health effects; Inflammation; Nanoparticles; Reactive oxygen species; Silica

Indexed keywords

AMORPHOUS SILICA; ANTI-INFLAMMATORY DRUGS; BIOLOGICAL RESPONSE; CYTOKINES; CYTOTOXIC; DIFFERENT SIZES; DRUG CARRIER; ENVIRONMENTAL AND HEALTH EFFECTS; IN-VITRO EVALUATION; INFLAMMATION; INFLAMMATORY PROPERTIES; METABOLIC ACTIVITY; PHYSICOCHEMICAL PROPERTY; POTENTIAL APPLICATIONS; REACTIVE OXYGEN SPECIES; SCREENING APPROACHES; SILICA NANOPARTICLES;

CYTOTOXICITY; MACROPHAGES; PATHOLOGY; SILICA;

NANOPARTICLES;

REACTIVE OXYGEN METABOLITE; SILICON DIOXIDE;

ANIMAL CELL; ARTICLE; CELL ACTIVITY; CELL DAMAGE; CELL MEMBRANE; CELL METABOLISM; CELL SIZE; CONTROLLED STUDY; CYTOKINE RELEASE; CYTOTOXICITY; IN VITRO STUDY; MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN AGGREGATION; ZETA POTENTIAL;

EID: 84857061413     PISSN: 13880764     EISSN: 1572896X     Source Type: Journal    
DOI: 10.1007/s11051-011-0586-6     Document Type: Article

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