메뉴 건너뛰기




Volumn 36, Issue 2, 2012, Pages 244-253

Chronic HO-1 induction with cobalt protoporphyrin (CoPP) treatment increases oxygen consumption, activity, heat production and lowers body weight in obese melanocortin-4 receptor-deficient mice

Author keywords

adiponectin; diabetes; gene knockout; heme oxygenase; leptin; metabolism

Indexed keywords

ADIPONECTIN; CARBON DIOXIDE; GLUCOSE; HEME OXYGENASE 1; INSULIN; MELANOCORTIN 4 RECEPTOR; PROTOPORPHYRIN COBALT;

EID: 84857048733     PISSN: 03070565     EISSN: 14765497     Source Type: Journal    
DOI: 10.1038/ijo.2011.78     Document Type: Article
Times cited : (37)

References (40)
  • 2
    • 51449087136 scopus 로고    scopus 로고
    • L-4F treatment reduces adiposity, increases adiponectin levels, and improves insulin sensitivity in obese mice
    • Peterson SJ, Drummond G, Kim DH, Li M, Kruger AL, Ikehara S et al. L-4F treatment reduces adiposity, increases adiponectin levels, and improves insulin sensitivity in obese mice. J Lipid Res 2008; 49: 1658-1669.
    • (2008) J Lipid Res , vol.49 , pp. 1658-1669
    • Peterson, S.J.1    Drummond, G.2    Kim, D.H.3    Li, M.4    Kruger, A.L.5    Ikehara, S.6
  • 3
    • 67650555703 scopus 로고    scopus 로고
    • The L-4F mimetic peptide prevents insulin resistance through increased levels of HO-1, pAMPK, and pAKT in obese mice
    • Peterson SJ, Kim DH, Li M, Positano V, Vanella L, Rodella LF et al. The L-4F mimetic peptide prevents insulin resistance through increased levels of HO-1, pAMPK, and pAKT in obese mice. J Lipid Res 2009; 50: 1293-1304.
    • (2009) J Lipid Res , vol.50 , pp. 1293-1304
    • Peterson, S.J.1    Kim, D.H.2    Li, M.3    Positano, V.4    Vanella, L.5    Rodella, L.F.6
  • 4
    • 0026315637 scopus 로고
    • Intracerebroventricular administration of cobalt protoporphyrin elicits prolonged weight reduction in rats
    • Galbraith RA, Kappas A. Intracerebroventricular administration of cobalt protoporphyrin elicits prolonged weight reduction in rats. Am J Physiol 1991; 261 (Part 2): R1395-R1401.
    • (1991) Am J Physiol , vol.261 , Issue.PART 2
    • Galbraith, R.A.1    Kappas, A.2
  • 5
    • 0026792872 scopus 로고
    • Injection of cobalt protoporphyrin into the medial nuclei of the hypothalamus elicits weight loss
    • Galbraith RA, Kow LM, Pfaff D, Kappas A. Injection of cobalt protoporphyrin into the medial nuclei of the hypothalamus elicits weight loss. Am J Physiol 1992; 263 (Part 2): R805-R812.
    • (1992) Am J Physiol , vol.263 , Issue.PART 2
    • Galbraith, R.A.1    Kow, L.M.2    Pfaff, D.3    Kappas, A.4
  • 6
    • 0026739793 scopus 로고
    • Hypothalamic mechanism for cobalt protoporphyrin-induced hypophagia and weight loss: Inhibition of the feeding response to NP.Y
    • Galbraith RA, Chua Jr. SC, Kappas A. Hypothalamic mechanism for cobalt protoporphyrin-induced hypophagia and weight loss: Inhibition of the feeding response to NPY. Brain Res Mol Brain Res 1992; 15: 298-302.
    • (1992) Brain Res Mol Brain Res , vol.15 , pp. 298-302
    • Galbraith, R.A.1    Chua Jr., S.C.2    Kappas, A.3
  • 7
    • 0028104980 scopus 로고
    • Lack of NPY-induced feeding in cobalt protoporphyrin-treated rats is a postreceptor defect
    • DOI 10.1016/0031-9384(94)90336-0
    • Turner MB, Corp ES, Galbraith RA. Lack of NPY-induced feeding in cobalt protoporphyrin-treated rats is a postreceptor defect. Physiol Behav 1994; 56: 1009-1014. (Pubitemid 24337118)
    • (1994) Physiology and Behavior , vol.56 , Issue.5 , pp. 1009-1014
    • Turner, M.B.1    Corp, E.S.2    Galbraith, R.A.3
  • 8
    • 33744946529 scopus 로고    scopus 로고
    • The weight loss elicited by cobalt protoporphyrin is related to decreased activity of nitric oxide synthase in the hypothalamus
    • DOI 10.1152/japplphysiol.01169.2005
    • Li M, Vizzard MA, Jaworski DM, Galbraith RA. The weight loss elicited by cobalt protoporphyrin is related to decreased activity of nitric oxide synthase in the hypothalamus. J Appl Physiol 2006; 100: 1983-1991. (Pubitemid 43845874)
    • (2006) Journal of Applied Physiology , vol.100 , Issue.6 , pp. 1983-1991
    • Li, M.1    Vizzard, M.A.2    Jaworski, D.M.3    Galbraith, R.A.4
  • 9
    • 77952893301 scopus 로고    scopus 로고
    • Obesity-induced hypertension: Role of sympathetic nervous system leptin and melanocortins
    • Hall JE, da Silva AA, do Carmo JM, Dubinion J, Hamza S, Munusamy S et al. Obesity-induced hypertension: Role of sympathetic nervous system, leptin, and melanocortins. J Biol Chem 2010; 285: 17271-17276.
    • (2010) J Biol Chem , vol.285 , pp. 17271-17276
    • Hall, J.E.1    Da Silva, A.A.2    Do Carmo, J.M.3    Dubinion, J.4    Hamza, S.5    Munusamy, S.6
  • 13
    • 0031662163 scopus 로고    scopus 로고
    • A frameshift mutation in human MC4R is associated with a dominant form of obesity [2]
    • DOI 10.1038/2407
    • Vaisse C, Clement K, Guy-Grand B, Froguel P. A frameshift mutation in human MC4R is associated with a dominant form of obesity. Nat Genet 1998; 20: 113-114. (Pubitemid 28455439)
    • (1998) Nature Genetics , vol.20 , Issue.2 , pp. 113-114
    • Vaisse, C.1    Clement, K.2    Guy-Grand, B.3    Froguel, P.4
  • 14
  • 15
    • 4644240052 scopus 로고    scopus 로고
    • Melanocortin 4 receptor gene variation is associated with severe obesity in Pima Indians
    • DOI 10.2337/diabetes.53.10.2696
    • Ma L, Tataranni PA, Bogardus C, Baier LJ. Melanocortin 4 receptor gene variation is associated with severe obesity in Pima Indians. Diabetes 2004; 53: 2696-2699. (Pubitemid 39299281)
    • (2004) Diabetes , vol.53 , Issue.10 , pp. 2696-2699
    • Ma, L.1    Tataranni, P.A.2    Bogardus, C.3    Baier, L.J.4
  • 16
    • 77449101244 scopus 로고    scopus 로고
    • A recurring problem with the analysis of energy expenditure in genetic models expressing lean and obese phenotypes
    • Butler AA, Kozak LP. A recurring problem with the analysis of energy expenditure in genetic models expressing lean and obese phenotypes. Diabetes 2010; 59: 323-329.
    • (2010) Diabetes , vol.59 , pp. 323-329
    • Butler, A.A.1    Kozak, L.P.2
  • 19
    • 33744931155 scopus 로고    scopus 로고
    • Heme oxygenase-1 enhances renal mitochondrial transport carriers and cytochrome c oxidase activity in experimental diabetes
    • DOI 10.1074/jbc.M510595200
    • Di Noia MA, Van Driesche S, Palmieri F, Yang LM, Quan S, Goodman AI et al. Heme oxygenase-1 enhances renal mitochondrial transport carriers and cytochrome C oxidase activity in experimental diabetes. J Biol Chem 2006; 281: 15687-15693. (Pubitemid 43848455)
    • (2006) Journal of Biological Chemistry , vol.281 , Issue.23 , pp. 15687-15693
    • Di Noia, M.A.1    Van Driesche, S.2    Palmieri, F.3    Yang, L.-M.4    Quan, S.5    Goodman, A.I.6    Abraham, N.G.7
  • 21
    • 58149328569 scopus 로고    scopus 로고
    • Heme oxygenase-1 regulates cardiac mitochondrial biogenesis via Nrf2-mediated transcriptional control of nuclear respiratory factor-1
    • Piantadosi CA, Carraway MS, Babiker A, Suliman HB. Heme oxygenase-1 regulates cardiac mitochondrial biogenesis via Nrf2-mediated transcriptional control of nuclear respiratory factor-1. Circ Res 2008; 103: 1232-1240.
    • (2008) Circ Res , vol.103 , pp. 1232-1240
    • Piantadosi, C.A.1    Carraway, M.S.2    Babiker, A.3    Suliman, H.B.4
  • 23
    • 41149155892 scopus 로고    scopus 로고
    • Treatment of obese diabetic mice with a heme oxygenase inducer reduces visceral and subcutaneous adiposity, increases adiponectin levels, and improves insulin sensitivity and glucose tolerance
    • Li M, Kim DH, Tsenovoy PL, Peterson SJ, Rezzani R, Rodella LF et al. Treatment of obese diabetic mice with a heme oxygenase inducer reduces visceral and subcutaneous adiposity, increases adiponectin levels, and improves insulin sensitivity and glucose tolerance. Diabetes 2008; 57: 1526-1535.
    • (2008) Diabetes , vol.57 , pp. 1526-1535
    • Li, M.1    Kim, D.H.2    Tsenovoy, P.L.3    Peterson, S.J.4    Rezzani, R.5    Rodella, L.F.6
  • 24
    • 0020485917 scopus 로고
    • Activation of purified guanylate cyclase by nitric oxide requires heme Comparison of heme-deficient, heme-reconstituted and heme-containing forms of soluble enzyme from bovine lung
    • Ignarro LJ, Degnan JN, Baricos WH, Kadowitz PJ, Wolin MS. Activation of purified guanylate cyclase by nitric oxide requires heme. Comparison of heme-deficient, heme-reconstituted and heme-containing forms of soluble enzyme from bovine lung. Biochim Biophys Acta 1982; 718: 49-59.
    • (1982) Biochim Biophys Acta , vol.718 , pp. 49-59
    • Ignarro, L.J.1    Degnan, J.N.2    Baricos, W.H.3    Kadowitz, P.J.4    Wolin, M.S.5
  • 25
    • 0033583305 scopus 로고    scopus 로고
    • EPR characterization of axial bond in metal center of native and cobalt-substituted guanylate cyclase
    • Makino R, Matsuda H, Obayashi E, Shiro Y, Iizuka T, Hori H. EPR characterization of axial bond in metal center of native and cobalt-substituted guanylate cyclase. J Biol Chem 1999; 274: 7714-7723.
    • (1999) J Biol Chem , vol.274 , pp. 7714-7723
    • Makino, R.1    Matsuda, H.2    Obayashi, E.3    Shiro, Y.4    Iizuka, T.5    Hori, H.6
  • 26
    • 77953730770 scopus 로고    scopus 로고
    • Heme arginate therapy enhanced adiponectin and atrial natriuretic peptide, but abated endothelin-1 with attenuation of kidney histopathological lesions in mineralocorticoid-induced hypertension
    • Ndisang JF, Jadhav A. Heme arginate therapy enhanced adiponectin and atrial natriuretic peptide, but abated endothelin-1 with attenuation of kidney histopathological lesions in mineralocorticoid-induced hypertension. J Pharmacol Exp Ther 2010; 334: 87-98.
    • (2010) J Pharmacol Exp Ther , vol.334 , pp. 87-98
    • Ndisang, J.F.1    Jadhav, A.2
  • 27
    • 61749098712 scopus 로고    scopus 로고
    • Heme oxygenase-1 induction remodels adipose tissue and improves insulin sensitivity in obesity-induced diabetic rats
    • Nicolai A, Li M, Kim DH, Peterson SJ, Vanella L, Positano V et al. Heme oxygenase-1 induction remodels adipose tissue and improves insulin sensitivity in obesity-induced diabetic rats. Hypertension 2009; 53: 508-515.
    • (2009) Hypertension , vol.53 , pp. 508-515
    • Nicolai, A.1    Li, M.2    Kim, D.H.3    Peterson, S.J.4    Vanella, L.5    Positano, V.6
  • 28
    • 0026542512 scopus 로고
    • Normal and heat-induced patterns of expression of heme oxygenase-1 (HSP32) in rat brain: Hyperthermia causes rapid induction of mRNA and protein
    • Ewing JF, Haber SN, Maines MD. Normal and heat-induced patterns of expression of heme oxygenase-1 (HSP32) in rat brain: Hyperthermia causes rapid induction of mRNA and protein. J Neurochem 1992; 58: 1140-1149.
    • (1992) J Neurochem , vol.58 , pp. 1140-1149
    • Ewing, J.F.1    Haber, S.N.2    Maines, M.D.3
  • 31
    • 66649132533 scopus 로고    scopus 로고
    • Up-regulating the hemeoxygenase system enhances insulin sensitivity and improves glucose metabolism in insulin-resistant diabetes in Goto-Kakizaki rats
    • Ndisang JF, Jadhav A. Up-regulating the hemeoxygenase system enhances insulin sensitivity and improves glucose metabolism in insulin-resistant diabetes in Goto-Kakizaki rats. Endocrinology 2009; 150: 2627-2636.
    • (2009) Endocrinology , vol.150 , pp. 2627-2636
    • Ndisang, J.F.1    Jadhav, A.2
  • 32
    • 66449100734 scopus 로고    scopus 로고
    • The heme oxygenase system abates hyperglycemia in Zucker diabetic fatty rats by potentiating insulin-sensitizing pathways
    • Ndisang JF, Lane N, Jadhav A. The heme oxygenase system abates hyperglycemia in Zucker diabetic fatty rats by potentiating insulin-sensitizing pathways. Endocrinology 2009; 150: 2098-2108.
    • (2009) Endocrinology , vol.150 , pp. 2098-2108
    • Ndisang, J.F.1    Lane, N.2    Jadhav, A.3
  • 33
    • 33745986945 scopus 로고    scopus 로고
    • Melanocortin-4 receptor mediates chronic cardiovascular and metabolic actions of leptin
    • DOI 10.1161/01.HYP.0000227966.36744.d9, PII 0000426820060700000014
    • Tallam LS, da Silva AA, Hall JE. Melanocortin-4 receptor mediates chronic cardiovascular and metabolic actions of leptin. Hypertension 2006; 48: 58-64. (Pubitemid 44297525)
    • (2006) Hypertension , vol.48 , Issue.1 , pp. 58-64
    • Tallam, L.S.1    Da Silva, A.A.2    Hall, J.E.3
  • 34
    • 25144451723 scopus 로고    scopus 로고
    • Serotonergic pathways converge upon central melanocortin systems to regulate energy balance
    • DOI 10.1016/j.peptides.2004.12.028, PII S0196978105002238, The Melanocortin Pathway 2005
    • Zhou L, Williams T, Lachey JL, Kishi T, Cowley MA, Heisler LK. Serotonergic pathways converge upon central melanocortin systems to regulate energy balance. Peptides 2005; 26: 1728-1732. (Pubitemid 41354530)
    • (2005) Peptides , vol.26 , Issue.10 , pp. 1728-1732
    • Zhou, L.1    Williams, T.2    Lachey, J.L.3    Kishi, T.4    Cowley, M.A.5    Heisler, L.K.6
  • 35
    • 40849135860 scopus 로고    scopus 로고
    • 2C receptor agonist promotes hypophagia via downstream activation of melanocortin 4 receptors
    • DOI 10.1210/en.2007-1321
    • Lam DD, Przydzial MJ, Ridley SH, Yeo GS, Rochford JJ, O'Rahilly S et al. Serotonin 5-HT2C receptor agonist promotes hypophagia via downstream activation of melanocortin 4 receptors. Endocrinology 2008; 149: 1323-1328. (Pubitemid 351397929)
    • (2008) Endocrinology , vol.149 , Issue.3 , pp. 1323-1328
    • Lam, D.D.1    Przydzial, M.J.2    Ridley, S.H.3    Yeo, G.S.H.4    Rochford, J.J.5    O'Rahilly, S.6    Heisler, L.K.7
  • 37
    • 1842453288 scopus 로고    scopus 로고
    • Assessment of a small molecule melanocortin-4 receptor-specific agonist on energy homeostasis
    • DOI 10.1016/j.brainres.2003.10.041, PII S0006899303039878
    • Cepoi D, Phillips T, Cismowski M, Goodfellow VS, Ling N, Cone RD et al. Assessment of a small molecule melanocortin-4 receptor-specific agonist on energy homeostasis. Brain Res 2004; 1000: 64-71. (Pubitemid 38446490)
    • (2004) Brain Research , vol.1000 , Issue.1-2 , pp. 64-71
    • Cepoi, D.1    Phillips, T.2    Cismowski, M.3    Goodfellow, V.S.4    Ling, N.5    Cone, R.D.6    Fan, W.7
  • 38
    • 18844432794 scopus 로고    scopus 로고
    • The regulation of feeding and metabolic rate and the prevention of murine cancer cachexia with a small-molecule melanocortin-4 receptor antagonist
    • DOI 10.1210/en.2005-0142
    • Markison S, Foster AC, Chen C, Brookhart GB, Hesse A, Hoare SR et al. The regulation of feeding and metabolic rate and the prevention of murine cancer cachexia with a small-molecule melanocortin-4 receptor antagonist. Endocrinology 2005; 146: 2766-2773. (Pubitemid 40695581)
    • (2005) Endocrinology , vol.146 , Issue.6 , pp. 2766-2773
    • Markison, S.1    Foster, A.C.2    Chen, C.3    Brookhart, G.B.4    Hesse, A.5    Hoare, S.R.J.6    Fleck, B.A.7    Brown, B.T.8    Marks, D.L.9
  • 40
    • 0038051071 scopus 로고    scopus 로고
    • Knockout studies defining different roles for melanocortin receptors in energy homeostasis
    • Butler AA, Cone RD. Knockout studies defining different roles for melanocortin receptors in energy homeostasis. Ann NY Acad Sci 2003; 994: 240-245. (Pubitemid 36793873)
    • (2003) Annals of the New York Academy of Sciences , vol.994 , pp. 240-245
    • Butler, A.A.1    Cone, R.D.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.