CaMKII antisense oligodeoxynucleotides protect against ischemia-induced neuronal death in the rat hippocampus

Journal of the Neurological Sciences

Volumn 314, Issue 1-2, 2012, Pages 104-110

  Liu, Zhi'An ^a,b,c   Xu, Jing ^a   Shen, Xiaojun ^d   Lv, Chun'E ^b   Xu, Tiejun ^b,c   Pei, Dongsheng ^a  

^a Key Laboratory of Biological Cancer Therapy of Jiangsu Province   (China)

^b XUZHOU MEDICAL UNIVERSITY   (China)

^c Key Laboratory of Brain Disease Bioinformation of Jiangsu Province   (China)

^d Xuzhou First People's Hospital   (China)

Author keywords

CaMKII; CaMKII antisense oligodeoxynucleotides; Cerebral ischemia; GluR6; Neuroprotection; PSD 95

Indexed keywords

ANTISENSE OLIGODEOXYNUCLEOTIDE; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II ANTISENSE OLIGODEOXYNUCLEOTIDE; MITOGEN ACTIVATED PROTEIN KINASE 3; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN ISCHEMIA; CELL DEATH; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; HIPPOCAMPUS; IMMUNOBLOTTING; IMMUNOPRECIPITATION; MALE; NERVE CELL NECROSIS; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN EXPRESSION; RAT; REPERFUSION INJURY; SIGNAL TRANSDUCTION;

ANIMALS; BLOTTING, WESTERN; BRAIN ISCHEMIA; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 2; CELL DEATH; CEREBROVASCULAR CIRCULATION; ENZYME ACTIVATION; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HIPPOCAMPUS; IMMUNOPRECIPITATION; IN SITU NICK-END LABELING; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; MEMBRANE PROTEINS; MITOGEN-ACTIVATED PROTEIN KINASE 10; NEURONS; NEUROPROTECTIVE AGENTS; OLIGODEOXYRIBONUCLEOTIDES, ANTISENSE; PHOSPHORYLATION; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, KAINIC ACID;

EID: 84857040394     PISSN: 0022510X     EISSN: 18785883     Source Type: Journal    
DOI: 10.1016/j.jns.2011.10.012     Document Type: Article

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