A new genetic abnormality leading to TP53 gene deletion in chronic lymphocytic leukaemia

British Journal of Haematology

Volumn 156, Issue 5, 2012, Pages 612-618

  López, Cristina ^a,b   Baumann, Tycho ^b   Costa, Dolors ^b,c   López Guerra, Mónica ^b   Navarro, Alba ^b   Gómez, Cándida ^b   Arias, Amparo ^b   Muñoz, Concha ^b,c   Rozman, María ^b,c   Villamor, Neus ^b,c   Colomer, Dolors ^b,c   Montserrat, Emili ^b,c   Campo, Elías ^b,c   Carrió, Ana ^b,c  

^a Fundació Privada Clinic per A la Recerca Biomèdica   (Spain)

^b Hospital Clinic   (Spain)

^c INSTITUT D INVESTIGACIONS BIOMÈDIQUES AUGUST PI I SUNYER IDIBAPS   (Spain)

Author keywords

Chronic lymphocytic leukaemia; Dic(8; 17)(p11; p11); Recurrent chromosomal abnormality; TP53 gene; Unbalanced translocation

Indexed keywords

IMMUNOGLOBULIN HEAVY CHAIN; PHENYLALANINE; PROTEIN P53; VALINE;

ADULT; AGED; AMINO ACID SUBSTITUTION; ARTICLE; CASE REPORT; CHROMOSOME 17P; CHROMOSOME 8P; CHROMOSOME ANALYSIS; CHROMOSOME ARM; CHROMOSOME G BAND; CHROMOSOME LOSS; CHROMOSOME TRANSLOCATION 17; CHROMOSOME TRANSLOCATION 8; CHRONIC LYMPHATIC LEUKEMIA; CLINICAL FEATURE; DISEASE COURSE; FEMALE; FLUORESCENCE IN SITU HYBRIDIZATION; GENE DELETION; GENE MUTATION; HOMOLOGOUS RECOMBINATION; HUMAN; MALE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROGNOSIS; SEGMENTAL DUPLICATION; TUMOR SUPPRESSOR GENE;

AGED; AGED, 80 AND OVER; CHROMOSOMES, HUMAN, PAIR 17; CHROMOSOMES, HUMAN, PAIR 8; DNA MUTATIONAL ANALYSIS; FEMALE; GENE DELETION; GENES, IMMUNOGLOBULIN HEAVY CHAIN; GENES, P53; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; KARYOTYPE; LEUKEMIA, LYMPHOCYTIC, CHRONIC, B-CELL; MALE; MIDDLE AGED; MUTATION; PROGNOSIS; TRANSLOCATION, GENETIC;

EID: 84857033230     PISSN: 00071048     EISSN: 13652141     Source Type: Journal    
DOI: 10.1111/j.1365-2141.2011.08978.x     Document Type: Article

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