-
1
-
-
42549109108
-
Notochord-derived Shh concentrates in close association with the apically positioned basal body in neural target cells and forms a dynamic gradient during neural patterning
-
Chamberlain C.E., Jeong J., Guo C., Allen B.L., McMahon A.P. Notochord-derived Shh concentrates in close association with the apically positioned basal body in neural target cells and forms a dynamic gradient during neural patterning. Development 2008, 135:1097-1106.
-
(2008)
Development
, vol.135
, pp. 1097-1106
-
-
Chamberlain, C.E.1
Jeong, J.2
Guo, C.3
Allen, B.L.4
McMahon, A.P.5
-
2
-
-
0029777408
-
Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function
-
Chiang C., Litingtung Y., Lee E., Young K.E., Corden J.L., Westphal H., Beachy P.A. Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function. Nature 1996, 383:407-413.
-
(1996)
Nature
, vol.383
, pp. 407-413
-
-
Chiang, C.1
Litingtung, Y.2
Lee, E.3
Young, K.E.4
Corden, J.L.5
Westphal, H.6
Beachy, P.A.7
-
3
-
-
0035556715
-
Mammalian neural tube grafting experiments: an invitro system for mouse experimental embryology
-
Echevarría D., Vieira C., Martínez S. Mammalian neural tube grafting experiments: an invitro system for mouse experimental embryology. Int. J. Dev. Biol. 2001, 45:895-902.
-
(2001)
Int. J. Dev. Biol.
, vol.45
, pp. 895-902
-
-
Echevarría, D.1
Vieira, C.2
Martínez, S.3
-
4
-
-
48549091913
-
Haploinsufficiency of Six3 fails to activate Sonic hedgehog expression in the ventral forebrain and causes holoprosencephaly
-
Geng X., Speirs C., Lagutin O., Inbal A., Liu W., Solnica-Krezel L., Jeong Y., Epstein D.J., Oliver G. Haploinsufficiency of Six3 fails to activate Sonic hedgehog expression in the ventral forebrain and causes holoprosencephaly. Dev. Cell 2008, 15:236-247.
-
(2008)
Dev. Cell
, vol.15
, pp. 236-247
-
-
Geng, X.1
Speirs, C.2
Lagutin, O.3
Inbal, A.4
Liu, W.5
Solnica-Krezel, L.6
Jeong, Y.7
Epstein, D.J.8
Oliver, G.9
-
6
-
-
67649264419
-
Genes and signaling events that establish regional patterning of the mammalian forebrain
-
Hoch R.V., Rubenstein J.L., Pleasure S. Genes and signaling events that establish regional patterning of the mammalian forebrain. Semin. Cell Dev. Biol. 2009, 20:378-386.
-
(2009)
Semin. Cell Dev. Biol.
, vol.20
, pp. 378-386
-
-
Hoch, R.V.1
Rubenstein, J.L.2
Pleasure, S.3
-
7
-
-
34447329291
-
Ectopic sonic hedgehog signaling impairs telencephalic dorsal midline development: implication for human holoprosencephaly
-
Huang X., Litingtung Y., Chiang C. Ectopic sonic hedgehog signaling impairs telencephalic dorsal midline development: implication for human holoprosencephaly. Hum. Mol. Genet. 2007, 16:1454-1468.
-
(2007)
Hum. Mol. Genet.
, vol.16
, pp. 1454-1468
-
-
Huang, X.1
Litingtung, Y.2
Chiang, C.3
-
9
-
-
12944272018
-
Receptor-mediated endocytosis of soluble and membrane-tethered Sonic hedgehog by Patched-1
-
Incardona J.P., Lee J.H., Robertson C.P., Enga K., Kapur R.P., Roelink H. Receptor-mediated endocytosis of soluble and membrane-tethered Sonic hedgehog by Patched-1. Proc. Natl. Acad. Sci. USA 2000, 97:12044-12049.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 12044-12049
-
-
Incardona, J.P.1
Lee, J.H.2
Robertson, C.P.3
Enga, K.4
Kapur, R.P.5
Roelink, H.6
-
10
-
-
0037172658
-
Sonic hedgehog induces the segregation of patched and smoothened in endosomes
-
Incardona J.P., Gruenberg J., Roelink H. Sonic hedgehog induces the segregation of patched and smoothened in endosomes. Curr. Biol. 2002, 12:983-995.
-
(2002)
Curr. Biol.
, vol.12
, pp. 983-995
-
-
Incardona, J.P.1
Gruenberg, J.2
Roelink, H.3
-
11
-
-
79958210024
-
Boc and Gas1 each form distinct Shh receptor complexes with Ptch1 and are required for Shh-mediated cell proliferation
-
Izzi L., Lévesque M., Morin S., Laniel D., Wilkes B.C., Mille F., Krauss R.S., McMahon A.P., Allen B.L., Charron F. Boc and Gas1 each form distinct Shh receptor complexes with Ptch1 and are required for Shh-mediated cell proliferation. Dev. Cell 2011, 20:788-801.
-
(2011)
Dev. Cell
, vol.20
, pp. 788-801
-
-
Izzi, L.1
Lévesque, M.2
Morin, S.3
Laniel, D.4
Wilkes, B.C.5
Mille, F.6
Krauss, R.S.7
McMahon, A.P.8
Allen, B.L.9
Charron, F.10
-
12
-
-
34547549299
-
Mutations in LRP2, which encodes the multiligand receptor megalin, cause Donnai-Barrow and facio-oculo-acoustico-renal syndromes
-
Kantarci S., Al-Gazali L., Hill R.S., Donnai D., Black G.C., Bieth E., Chassaing N., Lacombe D., Devriendt K., Teebi A., et al. Mutations in LRP2, which encodes the multiligand receptor megalin, cause Donnai-Barrow and facio-oculo-acoustico-renal syndromes. Nat. Genet. 2007, 39:957-959.
-
(2007)
Nat. Genet.
, vol.39
, pp. 957-959
-
-
Kantarci, S.1
Al-Gazali, L.2
Hill, R.S.3
Donnai, D.4
Black, G.C.5
Bieth, E.6
Chassaing, N.7
Lacombe, D.8
Devriendt, K.9
Teebi, A.10
-
13
-
-
34249011892
-
Gas1 extends the range of Hedgehog action by facilitating its signaling
-
Martinelli D.C., Fan C.M. Gas1 extends the range of Hedgehog action by facilitating its signaling. Genes Dev. 2007, 21:1231-1243.
-
(2007)
Genes Dev.
, vol.21
, pp. 1231-1243
-
-
Martinelli, D.C.1
Fan, C.M.2
-
14
-
-
0037067722
-
Megalin functions as an endocytic sonic hedgehog receptor
-
McCarthy R.A., Barth J.L., Chintalapudi M.R., Knaak C., Argraves W.S. Megalin functions as an endocytic sonic hedgehog receptor. J.Biol. Chem. 2002, 277:25660-25667.
-
(2002)
J.Biol. Chem.
, vol.277
, pp. 25660-25667
-
-
McCarthy, R.A.1
Barth, J.L.2
Chintalapudi, M.R.3
Knaak, C.4
Argraves, W.S.5
-
15
-
-
33748929665
-
Epithelial trafficking of Sonic hedgehog by megalin
-
Morales C.R., Zeng J., El Alfy M., Barth J.L., Chintalapudi M.R., McCarthy R.A., Incardona J.P., Argraves W.S. Epithelial trafficking of Sonic hedgehog by megalin. J.Histochem. Cytochem. 2006, 54:1115-1127.
-
(2006)
J.Histochem. Cytochem.
, vol.54
, pp. 1115-1127
-
-
Morales, C.R.1
Zeng, J.2
El Alfy, M.3
Barth, J.L.4
Chintalapudi, M.R.5
McCarthy, R.A.6
Incardona, J.P.7
Argraves, W.S.8
-
16
-
-
0034107360
-
Genetics of ventral forebrain development and holoprosencephaly
-
Muenke M., Beachy P.A. Genetics of ventral forebrain development and holoprosencephaly. Curr. Opin. Genet. Dev. 2000, 10:262-269.
-
(2000)
Curr. Opin. Genet. Dev.
, vol.10
, pp. 262-269
-
-
Muenke, M.1
Beachy, P.A.2
-
17
-
-
0029164902
-
The role of the notochord and floor plate in inductive interactions
-
Placzek M. The role of the notochord and floor plate in inductive interactions. Curr. Opin. Genet. Dev. 1995, 5:499-506.
-
(1995)
Curr. Opin. Genet. Dev.
, vol.5
, pp. 499-506
-
-
Placzek, M.1
-
18
-
-
77953766440
-
Establishing and interpreting graded Sonic Hedgehog signaling during vertebrate neural tube patterning: the role of negative feedback
-
Ribes V., Briscoe J. Establishing and interpreting graded Sonic Hedgehog signaling during vertebrate neural tube patterning: the role of negative feedback. Cold Spring Harb. Perspect. Biol. 2009, 1:a002014.
-
(2009)
Cold Spring Harb. Perspect. Biol.
, vol.1
-
-
Ribes, V.1
Briscoe, J.2
-
19
-
-
23444440157
-
Floor plate and motor neuron induction by vhh-1, a vertebrate homolog of hedgehog expressed by the notochord
-
Roelink H., Augsburger A., Heemskerk J., Korzh V., Norlin S., Ruiz i Altaba A., Tanabe Y., Placzek M., Edlund T., Jessell T.M., et al. Floor plate and motor neuron induction by vhh-1, a vertebrate homolog of hedgehog expressed by the notochord. Cell 1994, 76:761-775.
-
(1994)
Cell
, vol.76
, pp. 761-775
-
-
Roelink, H.1
Augsburger, A.2
Heemskerk, J.3
Korzh, V.4
Norlin, S.5
Ruiz i Altaba, A.6
Tanabe, Y.7
Placzek, M.8
Edlund, T.9
Jessell, T.M.10
-
21
-
-
34547110771
-
Patched1 regulates hedgehog signaling at the primary cilium
-
Rohatgi R., Milenkovic L., Scott M.P. Patched1 regulates hedgehog signaling at the primary cilium. Science 2007, 317:372-376.
-
(2007)
Science
, vol.317
, pp. 372-376
-
-
Rohatgi, R.1
Milenkovic, L.2
Scott, M.P.3
-
22
-
-
0028019068
-
Complete cloning and sequencing of rat gp330/" megalin," a distinctive member of the low density lipoprotein receptor gene family
-
Saito A., Pietromonaco S., Loo A.K., Farquhar M.G. Complete cloning and sequencing of rat gp330/" megalin," a distinctive member of the low density lipoprotein receptor gene family. Proc. Natl. Acad. Sci. USA 1994, 91:9725-9729.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 9725-9729
-
-
Saito, A.1
Pietromonaco, S.2
Loo, A.K.3
Farquhar, M.G.4
-
23
-
-
0030891148
-
A binding site for Gli proteins is essential for HNF-3beta floor plate enhancer activity in transgenics and can respond to Shh invitro
-
Sasaki H., Hui C., Nakafuku M., Kondoh H. A binding site for Gli proteins is essential for HNF-3beta floor plate enhancer activity in transgenics and can respond to Shh invitro. Development 1997, 124:1313-1322.
-
(1997)
Development
, vol.124
, pp. 1313-1322
-
-
Sasaki, H.1
Hui, C.2
Nakafuku, M.3
Kondoh, H.4
-
24
-
-
77954955134
-
Sonic hedgehog functions through dynamic changes in temporal competence in the developing forebrain
-
Sousa V.H., Fishell G. Sonic hedgehog functions through dynamic changes in temporal competence in the developing forebrain. Curr. Opin. Genet. Dev. 2010, 20:391-399.
-
(2010)
Curr. Opin. Genet. Dev.
, vol.20
, pp. 391-399
-
-
Sousa, V.H.1
Fishell, G.2
-
25
-
-
13944258550
-
LRP2/megalin is required for patterning of the ventral telencephalon
-
Spoelgen R., Hammes A., Anzenberger U., Zechner D., Andersen O.M., Jerchow B., Willnow T.E. LRP2/megalin is required for patterning of the ventral telencephalon. Development 2005, 132:405-414.
-
(2005)
Development
, vol.132
, pp. 405-414
-
-
Spoelgen, R.1
Hammes, A.2
Anzenberger, U.3
Zechner, D.4
Andersen, O.M.5
Jerchow, B.6
Willnow, T.E.7
-
26
-
-
33745280611
-
The BMP antagonist Noggin promotes cranial and spinal neurulation by distinct mechanisms
-
Stottmann R.W., Berrong M., Matta K., Choi M., Klingensmith J. The BMP antagonist Noggin promotes cranial and spinal neurulation by distinct mechanisms. Dev. Biol. 2006, 295:647-663.
-
(2006)
Dev. Biol.
, vol.295
, pp. 647-663
-
-
Stottmann, R.W.1
Berrong, M.2
Matta, K.3
Choi, M.4
Klingensmith, J.5
-
27
-
-
0034738979
-
Effects of oncogenic mutations in Smoothened and Patched can be reversed by cyclopamine
-
Taipale J., Chen J.K., Cooper M.K., Wang B., Mann R.K., Milenkovic L., Scott M.P., Beachy P.A. Effects of oncogenic mutations in Smoothened and Patched can be reversed by cyclopamine. Nature 2000, 406:1005-1009.
-
(2000)
Nature
, vol.406
, pp. 1005-1009
-
-
Taipale, J.1
Chen, J.K.2
Cooper, M.K.3
Wang, B.4
Mann, R.K.5
Milenkovic, L.6
Scott, M.P.7
Beachy, P.A.8
-
28
-
-
33646103902
-
The cell surface membrane proteins Cdo and Boc are components and targets of the Hedgehog signaling pathway and feedback network in mice
-
Tenzen T., Allen B.L., Cole F., Kang J.S., Krauss R.S., McMahon A.P. The cell surface membrane proteins Cdo and Boc are components and targets of the Hedgehog signaling pathway and feedback network in mice. Dev. Cell 2006, 10:647-656.
-
(2006)
Dev. Cell
, vol.10
, pp. 647-656
-
-
Tenzen, T.1
Allen, B.L.2
Cole, F.3
Kang, J.S.4
Krauss, R.S.5
McMahon, A.P.6
-
29
-
-
0032759342
-
Molecular mechanisms of holoprosencephaly
-
Wallis D.E., Muenke M. Molecular mechanisms of holoprosencephaly. Mol. Genet. Metab. 1999, 68:126-138.
-
(1999)
Mol. Genet. Metab.
, vol.68
, pp. 126-138
-
-
Wallis, D.E.1
Muenke, M.2
-
30
-
-
0033064156
-
Mutations in the homeodomain of the human SIX3 gene cause holoprosencephaly
-
Wallis D.E., Roessler E., Hehr U., Nanni L., Wiltshire T., Richieri-Costa A., Gillessen-Kaesbach G., Zackai E.H., Rommens J., Muenke M. Mutations in the homeodomain of the human SIX3 gene cause holoprosencephaly. Nat. Genet. 1999, 22:196-198.
-
(1999)
Nat. Genet.
, vol.22
, pp. 196-198
-
-
Wallis, D.E.1
Roessler, E.2
Hehr, U.3
Nanni, L.4
Wiltshire, T.5
Richieri-Costa, A.6
Gillessen-Kaesbach, G.7
Zackai, E.H.8
Rommens, J.9
Muenke, M.10
-
31
-
-
0027079937
-
Low density lipoprotein receptor-related protein and gp330 bind similar ligands, including plasminogen activator-inhibitor complexes and lactoferrin, an inhibitor of chylomicron remnant clearance
-
Willnow T.E., Goldstein J.L., Orth K., Brown M.S., Herz J. Low density lipoprotein receptor-related protein and gp330 bind similar ligands, including plasminogen activator-inhibitor complexes and lactoferrin, an inhibitor of chylomicron remnant clearance. J.Biol. Chem. 1992, 267:26172-26180.
-
(1992)
J.Biol. Chem.
, vol.267
, pp. 26172-26180
-
-
Willnow, T.E.1
Goldstein, J.L.2
Orth, K.3
Brown, M.S.4
Herz, J.5
-
32
-
-
0029775625
-
Defective forebrain development in mice lacking gp330/megalin
-
Willnow T.E., Hilpert J., Armstrong S.A., Rohlmann A., Hammer R.E., Burns D.K., Herz J. Defective forebrain development in mice lacking gp330/megalin. Proc. Natl. Acad. Sci. USA 1996, 93:8460-8464.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 8460-8464
-
-
Willnow, T.E.1
Hilpert, J.2
Armstrong, S.A.3
Rohlmann, A.4
Hammer, R.E.5
Burns, D.K.6
Herz, J.7
-
33
-
-
35548983852
-
Lipoproteins and their receptors in embryonic development: more than cholesterol clearance
-
Willnow T.E., Hammes A., Eaton S. Lipoproteins and their receptors in embryonic development: more than cholesterol clearance. Development 2007, 134:3239-3249.
-
(2007)
Development
, vol.134
, pp. 3239-3249
-
-
Willnow, T.E.1
Hammes, A.2
Eaton, S.3
-
34
-
-
33646120095
-
Cdo functions at multiple points in the Sonic Hedgehog pathway, and Cdo-deficient mice accurately model human holoprosencephaly
-
Zhang W., Kang J.S., Cole F., Yi M.J., Krauss R.S. Cdo functions at multiple points in the Sonic Hedgehog pathway, and Cdo-deficient mice accurately model human holoprosencephaly. Dev. Cell 2006, 10:657-665.
-
(2006)
Dev. Cell
, vol.10
, pp. 657-665
-
-
Zhang, W.1
Kang, J.S.2
Cole, F.3
Yi, M.J.4
Krauss, R.S.5
|