The Nek8 protein kinase, mutated in the human cystic kidney disease nephronophthisis, is both activated and degraded during ciliogenesis

Human Molecular Genetics

Volumn 21, Issue 5, 2012, Pages 1155-1171

  Zalli, Detina ^a   Bayliss, Richard ^a   Fry, Andrew M ^a  

^a UNIVERSITY OF LEICESTER   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

NEK8 PROTEIN KINASE; PROTEIN KINASE; UNCLASSIFIED DRUG;

ARTICLE; AUTOPHOSPHORYLATION; CELL CYCLE; CELL MATURATION; CENTROSOME; CILIOGENESIS; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME DEGRADATION; ENZYME LOCALIZATION; ENZYME PHOSPHORYLATION; EUKARYOTIC FLAGELLUM; GENE MUTATION; HUMAN; HUMAN CELL; MUTANT; NEPHRONOPHTHISIS; PRIORITY JOURNAL; PROTEIN DOMAIN;

ANIMALS; CATALYTIC DOMAIN; CELL CYCLE; CELL LINE; CELL NUCLEUS; CENTROSOME; CILIA; ENZYME ACTIVATION; G0 PHASE; HUMANS; KIDNEY DISEASES, CYSTIC; MICE; MODELS, MOLECULAR; MUTANT PROTEINS; MUTATION; PHOSPHORYLATION; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN CONFORMATION; PROTEIN KINASES; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT FUSION PROTEINS;

EID: 84856971590     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddr544     Document Type: Article

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