메뉴 건너뛰기




Volumn 27, Issue SUPPL.2, 2012, Pages 85-88

Novel anti-fibrotic modalities for liver fibrosis: Molecular targeting and regenerative medicine in fibrosis therapy

Author keywords

Bone marrow; Collagen; Liver fibrosis; Smad; Transforming growth factor

Indexed keywords

ENHANCED GREEN FLUORESCENT PROTEIN; GRANULOCYTE COLONY STIMULATING FACTOR; SCATTER FACTOR; SMAD3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA; Y BOX BINDING PROTEIN 1;

EID: 84856962975     PISSN: 08159319     EISSN: 14401746     Source Type: Journal    
DOI: 10.1111/j.1440-1746.2011.07006.x     Document Type: Article
Times cited : (39)

References (18)
  • 1
    • 33846951514 scopus 로고    scopus 로고
    • Emerging insights into transforming growth factor-β Smad signal in hepatic fibrogenesis
    • Inagaki Y, Okazaki I. Emerging insights into transforming growth factor-β Smad signal in hepatic fibrogenesis. Gut 2007; 56: 284-92.
    • (2007) Gut , vol.56 , pp. 284-292
    • Inagaki, Y.1    Okazaki, I.2
  • 2
    • 0034802566 scopus 로고    scopus 로고
    • Angiotensin-II type 1 receptor interaction is a major regulator for liver fibrosis development in rats
    • Yoshiji H, Kuriyama S, Yoshii J etal. Angiotensin-II type 1 receptor interaction is a major regulator for liver fibrosis development in rats. Hepatology 2001; 34: 745-50.
    • (2001) Hepatology , vol.34 , pp. 745-750
    • Yoshiji, H.1    Kuriyama, S.2    Yoshii, J.3
  • 3
    • 18644369234 scopus 로고    scopus 로고
    • Effect of angiotensin receptor antagonist on liver fibrosis in early stages of chronic hepatitis C
    • Terui Y, Saito T, Watanabe H etal. Effect of angiotensin receptor antagonist on liver fibrosis in early stages of chronic hepatitis C. Hepatology 2002; 36: 1022.
    • (2002) Hepatology , vol.36 , pp. 1022
    • Terui, Y.1    Saito, T.2    Watanabe, H.3
  • 4
    • 7044222556 scopus 로고    scopus 로고
    • Therapeutic efficacy of an angiotensin II receptor antagonist in patients with nonalcoholic steatohepatitis
    • Yokohama S, Yoneda M, Haneda M etal. Therapeutic efficacy of an angiotensin II receptor antagonist in patients with nonalcoholic steatohepatitis. Hepatology 2004; 40: 1222-5.
    • (2004) Hepatology , vol.40 , pp. 1222-1225
    • Yokohama, S.1    Yoneda, M.2    Haneda, M.3
  • 5
    • 0028176086 scopus 로고
    • Transforming growth factor-β stimulates α2(I) collagen gene expression through a cis-acting element that contains an Sp1-binding site
    • Inagaki Y, Truter S, Ramirez F. Transforming growth factor-β stimulates α2(I) collagen gene expression through a cis-acting element that contains an Sp1-binding site. J. Biol. Chem. 1994; 269: 14828-34.
    • (1994) J. Biol. Chem. , vol.269 , pp. 14828-14834
    • Inagaki, Y.1    Truter, S.2    Ramirez, F.3
  • 6
    • 0034671506 scopus 로고    scopus 로고
    • Synergistic cooperation between Sp1 and Smad3/Smad4 mediates transforming growth factor β1 stimulation of α2(I) collagen (COL1A2) transcription
    • Zhang W, Ou J, Inagaki I, Greenwel P, Ramirez F. Synergistic cooperation between Sp1 and Smad3/Smad4 mediates transforming growth factor β1 stimulation of α2(I) collagen (COL1A2) transcription. J. Biol. Chem. 2000; 275: 39237-45.
    • (2000) J. Biol. Chem. , vol.275 , pp. 39237-39245
    • Zhang, W.1    Ou, J.2    Inagaki, I.3    Greenwel, P.4    Ramirez, F.5
  • 7
    • 0035844276 scopus 로고    scopus 로고
    • Interaction between GC box binding factors and Smad proteins modulates cell lineage-specific α2(I) collagen gene transcription
    • Inagaki Y, Nemoto T, Nakao A etal. Interaction between GC box binding factors and Smad proteins modulates cell lineage-specific α2(I) collagen gene transcription. J. Biol. Chem. 2001; 276: 16573-9.
    • (2001) J. Biol. Chem. , vol.276 , pp. 16573-16579
    • Inagaki, Y.1    Nemoto, T.2    Nakao, A.3
  • 8
    • 0035120166 scopus 로고    scopus 로고
    • Constitutive phosphorylation and nuclear localization of Smad3 are correlated with increased collagen gene transcription in activated hepatic stellate cells
    • Inagaki Y, Mamura M, Kanamaru Y etal. Constitutive phosphorylation and nuclear localization of Smad3 are correlated with increased collagen gene transcription in activated hepatic stellate cells. J. Cell. Physiol. 2001; 187: 117-23.
    • (2001) J. Cell. Physiol. , vol.187 , pp. 117-123
    • Inagaki, Y.1    Mamura, M.2    Kanamaru, Y.3
  • 9
    • 41349106964 scopus 로고    scopus 로고
    • Hepatocyte growth factor suppresses profibrogenic signal transduction via nuclear export of Smad3 with galectin-7
    • Inagaki Y, Higashi K, Kushida M etal. Hepatocyte growth factor suppresses profibrogenic signal transduction via nuclear export of Smad3 with galectin-7. Gastroenterology 2008; 134: 1180-90.
    • (2008) Gastroenterology , vol.134 , pp. 1180-1190
    • Inagaki, Y.1    Higashi, K.2    Kushida, M.3
  • 10
    • 0037900063 scopus 로고    scopus 로고
    • Y-box binding protein YB-1 mediates transcriptional repression of human α2(I) collagen gene expression by interferon-γ
    • Higashi K, Inagaki Y, Suzuki N etal. Y-box binding protein YB-1 mediates transcriptional repression of human α2(I) collagen gene expression by interferon-γ. J. Biol. Chem. 2003; 278: 5156-62.
    • (2003) J. Biol. Chem. , vol.278 , pp. 5156-5162
    • Higashi, K.1    Inagaki, Y.2    Suzuki, N.3
  • 11
    • 0242384852 scopus 로고    scopus 로고
    • Interferon-γ interferes with transforming growth factor-β signaling through direct interaction of YB-1 with Smad3
    • Higashi K, Inagaki Y, Fujimori K, Nakao A, Kaneko H, Nakatsuka I. Interferon-γ interferes with transforming growth factor-β signaling through direct interaction of YB-1 with Smad3. J. Biol. Chem. 2003; 278: 43470-9.
    • (2003) J. Biol. Chem. , vol.278 , pp. 43470-43479
    • Higashi, K.1    Inagaki, Y.2    Fujimori, K.3    Nakao, A.4    Kaneko, H.5    Nakatsuka, I.6
  • 12
    • 22344450669 scopus 로고    scopus 로고
    • Cell type-specific intervention of TGF-β/Smad signaling suppresses collagen gene expression and hepatic fibrosis in mice
    • Inagaki Y, Kushida M, Higashi K etal. Cell type-specific intervention of TGF-β/Smad signaling suppresses collagen gene expression and hepatic fibrosis in mice. Gastroenterology 2005; 129: 259-68.
    • (2005) Gastroenterology , vol.129 , pp. 259-268
    • Inagaki, Y.1    Kushida, M.2    Higashi, K.3
  • 13
    • 70350543918 scopus 로고    scopus 로고
    • A novel inhibitor of Smad-dependent transcriptional activation suppresses tissue fibrosis in mouse models of systemic sclerosis
    • Hasegawa M, Matsushita Y, Horikawa M etal. A novel inhibitor of Smad-dependent transcriptional activation suppresses tissue fibrosis in mouse models of systemic sclerosis. Arthritis Rheum. 2009; 60: 3465-75.
    • (2009) Arthritis Rheum. , vol.60 , pp. 3465-3475
    • Hasegawa, M.1    Matsushita, Y.2    Horikawa, M.3
  • 14
    • 79953011983 scopus 로고    scopus 로고
    • A novel small compound that promotes nuclear translocation of YB-1 ameliorates experimental hepatic fibrosis in mice
    • Higashi K, Tomigahara Y, Shiraki H etal. A novel small compound that promotes nuclear translocation of YB-1 ameliorates experimental hepatic fibrosis in mice. J. Biol. Chem. 2011; 286: 4485-92.
    • (2011) J. Biol. Chem. , vol.286 , pp. 4485-4492
    • Higashi, K.1    Tomigahara, Y.2    Shiraki, H.3
  • 15
    • 33846453528 scopus 로고    scopus 로고
    • Bone marrow-derived cells express matrix metalloproteinases and contribute to regression of liver fibrosis in mice
    • Higashiyama R, Inagaki Y, Hong YY etal. Bone marrow-derived cells express matrix metalloproteinases and contribute to regression of liver fibrosis in mice. Hepatology 2007; 45: 213-22.
    • (2007) Hepatology , vol.45 , pp. 213-222
    • Higashiyama, R.1    Inagaki, Y.2    Hong, Y.Y.3
  • 16
    • 34547543646 scopus 로고    scopus 로고
    • Granulocyte-colony stimulating factor promotes liver repair and induces oval cell migration and proliferation in rats
    • Piscaglia AC, Shupe TD, Oh S-H, Gasbarrini A, Petersen BE. Granulocyte-colony stimulating factor promotes liver repair and induces oval cell migration and proliferation in rats. Gastroenterology 2007; 133: 619-31.
    • (2007) Gastroenterology , vol.133 , pp. 619-631
    • Piscaglia, A.C.1    Shupe, T.D.2    Oh, S.-H.3    Gasbarrini, A.4    Petersen, B.E.5
  • 17
    • 47149102130 scopus 로고    scopus 로고
    • Granulocyte-colony stimulating factor induces proliferation of hepatic progenitors in alcoholic steatohepatitis: a randomized trial
    • Spahr L, Lambert J-F, Rubbia-Brandt L etal. Granulocyte-colony stimulating factor induces proliferation of hepatic progenitors in alcoholic steatohepatitis: a randomized trial. Hepatology 2008; 48: 221-9.
    • (2008) Hepatology , vol.48 , pp. 221-229
    • Spahr, L.1    Lambert, J.-F.2    Rubbia-Brandt, L.3
  • 18
    • 35748946620 scopus 로고    scopus 로고
    • Granulocyte-colony stimulating factor impairs liver regeneration in mice through the up-regulation of interleukin-1β
    • Ogiso T, Nagaki M, Takai S etal. Granulocyte-colony stimulating factor impairs liver regeneration in mice through the up-regulation of interleukin-1β. J. Hepatol. 2007; 47: 816-25.
    • (2007) J. Hepatol. , vol.47 , pp. 816-825
    • Ogiso, T.1    Nagaki, M.2    Takai, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.