Hematopoietic stem cell mobilization for gene therapy of adult patients with severe Β-thalassemia results of clinical trials using G-CSF or plerixafor in splenectomized and nonsplenectomized subjects

Molecular Therapy

Volumn 20, Issue 1, 2012, Pages 230-238

  Yannaki, Evangelia ^a   Papayannopoulou, Thalia ^b   Jonlin, Erica ^b   Zervou, Fani ^a   Karponi, Garyfalia ^a   Xagorari, Angeliki ^a   Becker, Pamela ^b   Psatha, Nikoleta ^a   Batsis, Ioannis ^a   Kaloyannidis, Panayotis ^a   Tahynopoulou, Varvara ^a   Constantinou, Varnavas ^a   Bouinta, Asimina ^a   Kotta, Konstantia ^a   Athanassiadou, Aglaia ^c   Anagnostopoulos, Achilles ^a   Fassas, Athanasios ^a   Stamatoyannopoulos, George ^b  

^a G PAPANICOLAOU HOSPITAL   (Greece)

^b UNIVERSITY OF WASHINGTON   (United States)

^c UNIVERSITY OF PATRAS   (Greece)

Author keywords

[No Author keywords available]

Indexed keywords

CD34 ANTIGEN; GRANULOCYTE COLONY STIMULATING FACTOR; HYDROXYUREA; PLERIXAFOR;

ADULT; ARTICLE; BETA THALASSEMIA; BONE PAIN; CLINICAL ARTICLE; CLINICAL EFFECTIVENESS; CLINICAL TRIAL; CONTROLLED STUDY; CRYOPRESERVATION; DIARRHEA; DISEASE SEVERITY; DOSE RESPONSE; DRUG DOSE ESCALATION; DRUG EFFECT; DRUG EFFICACY; DRUG SAFETY; DRUG TOLERABILITY; FEMALE; FEVER; HUMAN; HUMAN TISSUE; INJECTION SITE ERYTHEMA; LEUKOCYTOSIS; LOW DRUG DOSE; MALE; NAUSEA; NEUTROPENIA; OUTCOME ASSESSMENT; SPLENECTOMY; SPLENOMEGALY; STEM CELL GENE THERAPY; STEM CELL MOBILIZATION; THALASSEMIA MAJOR; THROMBOCYTOPENIA; TREATMENT DURATION;

EID: 84856962945     PISSN: 15250016     EISSN: 15250024     Source Type: Journal    
DOI: 10.1038/mt.2011.195     Document Type: Article

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