Smoking is associated with increased adrenal responsiveness, decreased prolactin levels and a more adverse lipid profile in 650 white patients with polycystic ovary syndrome

Gynecological Endocrinology

Volumn 28, Issue 3, 2012, Pages 170-174

  Glintborg, Dorte ^a   Mumm, Hanne ^a   Hougaard, David M ^b   Ravn, Pernille ^a   Andersen, Marianne ^a  

^a ODENSE UNIVERSITY HOSPITAL   (Denmark)

^b STATENS SERUM INSTITUT   (Denmark)

Author keywords

ACTH test; Diabetes; Insulin resistance; Oral glucose tolerance test; Smoking

Indexed keywords

CHOLESTEROL; CORTICOTROPIN; HYDROXYPROGESTERONE; LOW DENSITY LIPOPROTEIN; PROLACTIN; SEX HORMONE; TRIACYLGLYCEROL;

ADRENAL FUNCTION; ADULT; ARTICLE; BODY COMPOSITION; CONTROLLED STUDY; FEMALE; HIRSUTISM; HORMONE DETERMINATION; HUMAN; INSULIN RESISTANCE; MAJOR CLINICAL STUDY; ORAL GLUCOSE TOLERANCE TEST; OVARY POLYCYSTIC DISEASE; PREMENOPAUSE; PRIORITY JOURNAL; RISK FACTOR; SMOKING HABIT; TRANSVAGINAL ECHOGRAPHY;

17-ALPHA-HYDROXYPROGESTERONE; ADRENAL GLANDS; ADRENOCORTICOTROPIC HORMONE; ADULT; CHOLESTEROL; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; GLUCOSE TOLERANCE TEST; HUMANS; LIPIDS; LIPOPROTEINS, HDL; LIPOPROTEINS, LDL; POLYCYSTIC OVARY SYNDROME; PROLACTIN; RETROSPECTIVE STUDIES; SMOKING; TRIGLYCERIDES;

EID: 84856869885     PISSN: 09513590     EISSN: 14730766     Source Type: Journal    
DOI: 10.3109/09513590.2011.589926     Document Type: Article

References (24)

1. Glintborg D, Henriksen JE, Andersen M, Hagen C, Hangaard J, Rasmussen PE, Schousboe K, Hermann A P. Prevalence of endocrine diseases and abnormal glucose tolerance tests in 340 Caucasian premenopausal women with hirsutism as the referral diagnosis. Fertil Steril 2004;82:1570-1579. (Pubitemid 39611385)
2. Rotterdam ESHRE/ASRM-Sponsored PCOS Consensus Workshop Group. Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome. Fertil Steril 2004;1:19-25.
3. Glintborg D, Andersen M. An update on the pathogenesis, infammation, and metabolism in hirsutism and polycystic ovary syndrome. Gynecol Endocrinol 2010;26:281-296.
4. Wild RA, Carmina E, Diamanti-Kandarakis E, Dokras A, Escobar-Morreale HF, Futterweit W, Lobo R, et al. Assessment of cardiovascular risk and prevention of cardiovascular disease in women with the polycystic ovary syndrome: a consensus statement by the Androgen Excess and Polycystic Ovary Syndrome (AE-PCOS) Society. J Clin Endocrinol Metab 2010;95:2038-2049.
5. Ambrose JA, Barua RS. The pathophysiology of cigarette smoking and cardiovascular disease: an update. J Am Coll Cardiol 2004;43:1731-1737. (Pubitemid 38622506)
6. Cupisti S, Häberle L, Dittrich R, Oppelt PG, Reissmann C, Kronawitter D, Beckmann M W, Mueller A. Smoking is associated with increased free testosterone and fasting insulin levels in women with polycystic ovary syndrome, resulting in aggravated insulin resistance. Fertil Steril 2010;94:673-677.
7. Glintborg D, Hermann A P, Brusgaard K, Hangaard J, Hagen C, Andersen M. Signifcantly higher adrenocorticotropin-stimulated cortisol and 17-hydroxyprogesterone levels in 337 consecutive, premenopausal, Caucasian, hirsute patients compared with healthy controls. J Clin Endocrinol Metab 2005;90:1347-1353. (Pubitemid 40463986)
8. Rohleder N, Kirschbaum C. The hypothalamic-pituitary-adrenal (HPA) axis in habitual smokers. Int J Psychophysiol 2006;59:236-243.
9. Fuxe K, Andersson K, Eneroth P, Härfstrand A, Agnati LF. Neuroendocrine actions of nicotine and of exposure to cigarette smoke: medical implications. Psychoneuroendocrinology 1989;14:19-41. (Pubitemid 19110829)
10. Glintborg D, Andersen M, Hagen C, Hermann AP. Higher bone mineral density in Caucasian, hirsute patients of reproductive age. Positive correlation of testosterone levels with bone mineral density in hirsutism. Clin Endocrinol (Oxf) 2005;62:683-691. (Pubitemid 40825938)
11. Glintborg D, Hermann A P, Andersen M, Hagen C, Beck-Nielsen H, Veldhuis JD, Henriksen JE. Efect of pioglitazone on glucose metabolism and luteinizing hormone secretion in women with polycystic ovary syndrome. Fertil Steril 2006;86:385-397. (Pubitemid 44137446)
12. Adams J, Polson D W, Franks S. Prevalence of polycystic ovaries in women with anovulation and idiopathic hirsutism. Br Med J (Clin Res Ed) 1986;293:355-359. (Pubitemid 16034121)
13. Salley KE, Wickham EP, Cheang KI, Essah PA, Karjane N W, Nestler JE. Glucose intolerance in polycystic ovary syndrome-a position statement of the Androgen Excess Society. J Clin Endocrinol Metab 2007;92:4546-4556. (Pubitemid 350223423)
14. Glintborg D, Mumm H, Hougaard D, Ravn P, Andersen M. Ethnic diferences in Rotterdam criteria and metabolic risk factors in a multiethnic group of women with PCOS studied in Denmark. Clin Endocrinol (Oxf) 2010;6:732-738.
15. Lykkesfeldt G, Bennett P, Lykkesfeldt AE, Micic S, Møller S, Svenstrup B. Abnormal androgen and oestrogen metabolism in men with steroid sulphatase defciency and recessive X-linked ichthyosis. Clin Endocrinol (Oxf) 1985;23:385-393. (Pubitemid 16216758)
16. Radziuk J. Insulin sensitivity and its measurement: structural commonalities among the methods. J Clin Endocrinol Metab 2000;85:4426-4433. (Pubitemid 32157613)
17. Björntorp P. The android woman-a risky condition. J Intern Med 1996;239:105-110.
18. Law MR, Cheng R, Hackshaw AK, Allaway S, Hale AK. Cigarette smoking, sex hormones and bone density in women. Eur J Epidemiol 1997;13:553-558. (Pubitemid 27306175)
19. Barth JH. Investigations in the assessment and management of patients with hirsutism. Curr Opin Obstet Gynecol 1997;9:187-192. (Pubitemid 27287461)
20. Hautanen A, Adlercreutz H. Hyperinsulinaemia, dyslipidaemia and exaggerated adrenal androgen response to adrenocorticotropin in male smokers. Diabetologia 1993;36:1275-1281. (Pubitemid 23353026)
21. Weisberg E. Smoking and reproductive health. Clin Reprod Fertil 1985;3:175-186. (Pubitemid 16116880)
22. Kapoor D, Jones TH. Smoking and hormones in health and endocrine disorders. Eur J Endocrinol 2005;152:491-499. (Pubitemid 40575793)
23. Sanders SR, Cuneo SP, Turzillo AM. Efects of nicotine and cotinine on bovine theca interna and granulosa cells. Reprod Toxicol 2002;16:795-800. (Pubitemid 35278501)
24. Chiolero A, Faeh D, Paccaud F, Cornuz J. Consequences of smoking for body weight, body fat distribution, and insulin resistance. Am J Clin Nutr 2008;87:801-809. (Pubitemid 351549222)