Linker-based hemisuccinate derivatives of artemisinin: Synthesis and antimalarial assessment against multidrug-resistant Plasmodium yoelii nigeriensis in mice(1)

Journal of Medicinal Chemistry

Volumn 55, Issue 3, 2012, Pages 1117-1126

  Singh, Chandan ^a   Kanchan, Rani ^a   Chaudhary, Sandeep ^a   Puri, Sunil K ^a  

^a CENTRAL DRUG RESEARCH INSTITUTE   (India)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIMALARIAL AGENT; ARTEMISININ DERIVATIVE; ARTESUNATE; DIHYDROARTEMISININ; HEMISUCCINATE DERIVATIVE; MACROGOL; SUCCINIC ACID DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIMALARIAL ACTIVITY; ARTICLE; CATALYSIS; CONTROLLED STUDY; DRUG EFFICACY; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; MALARIA CONTROL; MULTIDRUG RESISTANCE; NONHUMAN; PLASMODIUM YOELII; PLASMODIUM YOELII INFECTION; PLASMODIUM YOELII NIGERIENSIS;

ANIMALS; ANTIMALARIALS; ARTEMISININS; DRUG RESISTANCE, MULTIPLE; MALARIA; MICE; PLASMODIUM YOELII; SCHIZONTS; STRUCTURE-ACTIVITY RELATIONSHIP; SUCCINATES;

EID: 84856843923     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm2010699     Document Type: Article

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