메뉴 건너뛰기




Volumn 10, Issue 2, 2012, Pages 230-239

Treatment of non-small cell lung cancer in the older patient

Author keywords

Comprehensive geriatric assessment; Non small cell lung cancer; Older individuals

Indexed keywords

ANTINEOPLASTIC AGENT; BEVACIZUMAB; CARBOPLATIN; CISPLATIN; CYTOTOXIC AGENT; DOCETAXEL; ERLOTINIB; ETOPOSIDE; GEMCITABINE; NAVELBINE; PACLITAXEL; RECOMBINANT GRANULOCYTE COLONY STIMULATING FACTOR; VINBLASTINE;

EID: 84856833532     PISSN: 15401405     EISSN: 15401413     Source Type: Journal    
DOI: 10.6004/jnccn.2012.0021     Document Type: Review
Times cited : (26)

References (62)
  • 2
    • 67349223561 scopus 로고    scopus 로고
    • Therapeutic options for elderly patients with advanced non-small cell lung cancer
    • Avery EJ, Kessinger A, Ganti AK. Therapeutic options for elderly patients with advanced non-small cell lung cancer. Cancer Treat Rev 2009;35:340-344.
    • (2009) Cancer Treat Rev , vol.35 , pp. 340-344
    • Avery, E.J.1    Kessinger, A.2    Ganti, A.K.3
  • 7
    • 0021013073 scopus 로고
    • Assessing self-maintenance: Activities of daily living, mobility, and instrumental activities of daily living
    • Katz S. Assessing self-maintenance: activities of daily living, mobility, and instrumental activities of daily living. J Am Geriatr Soc 1983;31:721-727. (Pubitemid 14209563)
    • (1983) Journal of the American Geriatrics Society , vol.31 , Issue.12 , pp. 721-727
    • Katz, S.1
  • 8
    • 0014579432 scopus 로고
    • Assessment of older people: Self-maintaining and instrumental activities of daily living
    • Lawton MP, Brody EM. Assessment of older people: self-maintaining and instrumental activities of daily living. Gerontologist 1969;9:179-186.
    • (1969) Gerontologist , vol.9 , pp. 179-186
    • Lawton, M.P.1    Brody, E.M.2
  • 9
    • 27244438585 scopus 로고    scopus 로고
    • Pretreatment quality of life and functional status assessment significantly predict survival of elderly patients with advanced non-small-cell lung cancer receiving chemotherapy: A prognostic analysis of the multicenter Italian lung cancer in the elderly study
    • Maione P, Perrone F, Gallo C, et al. Pretreatment quality of life and functional status assessment significantly predict survival of elderly patients with advanced non-small-cell lung cancer receiving chemotherapy: a prognostic analysis of the multicenter Italian lung cancer in the elderly study. J Clin Oncol 2005;23:6865-6872.
    • (2005) J Clin Oncol , vol.23 , pp. 6865-6872
    • Maione, P.1    Perrone, F.2    Gallo, C.3
  • 10
    • 34249774066 scopus 로고    scopus 로고
    • Comprehensive geriatric assessment for older patients with cancer
    • DOI 10.1200/JCO.2007.10.6559
    • Extermann M, Hurria A. Comprehensive geriatric assessment for older patients with cancer. J Clin Oncol 2007;25:1824-1831. (Pubitemid 46860271)
    • (2007) Journal of Clinical Oncology , vol.25 , Issue.14 , pp. 1824-1831
    • Extermann, M.1    Hurria, A.2
  • 11
    • 79953836199 scopus 로고    scopus 로고
    • Implementing a geriatric assessment in cooperative group clinical cancer trials: CALGB 360401
    • Hurria A, Cirrincione CT, Muss HB, et al. Implementing a geriatric assessment in cooperative group clinical cancer trials: CALGB 360401. J Clin Oncol 2011;29:1290-1296.
    • (2011) J Clin Oncol , vol.29 , pp. 1290-1296
    • Hurria, A.1    Cirrincione, C.T.2    Muss, H.B.3
  • 12
    • 79955059692 scopus 로고    scopus 로고
    • Quality of life, geriatric assessment and survival in elderly patients with non-small-cell lung cancer treated with carboplatin-gemcitabine or carboplatin-paclitaxel: NVALT-3 a phase III study
    • Biesma B, Wymenga AN, Vincent A, et al. Quality of life, geriatric assessment and survival in elderly patients with non-small-cell lung cancer treated with carboplatin-gemcitabine or carboplatin-paclitaxel: NVALT-3 a phase III study. Ann Oncol 2011;22:1520-1527.
    • (2011) Ann Oncol , vol.22 , pp. 1520-1527
    • Biesma, B.1    Wymenga, A.N.2    Vincent, A.3
  • 13
    • 37549012238 scopus 로고    scopus 로고
    • Shall we operate? Preoperative assessment in elderly cancer patients (PACE) can help. A SIOG surgical task force prospective study
    • Audisio RA, Pope D, Ramesh HS, et al. Shall we operate? Preoperative assessment in elderly cancer patients (PACE) can help. A SIOG surgical task force prospective study. Crit Rev Oncol Hematol 2008;65:156-163.
    • (2008) Crit Rev Oncol Hematol , vol.65 , pp. 156-163
    • Audisio, R.A.1    Pope, D.2    Ramesh, H.S.3
  • 14
    • 17644364420 scopus 로고    scopus 로고
    • Preoperative assessment of surgical risk in oncogeriatric patients
    • DOI 10.1634/theoncologist.10-4-262
    • Audisio RA, Ramesh H, Longo WE, et al. Preoperative assessment of surgical risk in oncogeriatric patients. Oncologist 2005;10:262-268. (Pubitemid 40559591)
    • (2005) Oncologist , vol.10 , Issue.4 , pp. 262-268
    • Audisio, R.A.1    Ramesh, H.2    Longo, W.E.3    Zbar, A.P.4    Pope, D.5
  • 16
    • 84870958838 scopus 로고    scopus 로고
    • Relationship between components of the comprehensive geriatric assessment (CGA), chemotherapy dose intensity, and overall survival in a colorectal cancer (CRC) cohort age 65 and older
    • [abstract]. Abstract 9000
    • Ramsdale EE, Polite BN, Bylow KA, et al. Relationship between components of the comprehensive geriatric assessment (CGA), chemotherapy dose intensity, and overall survival in a colorectal cancer (CRC) cohort age 65 and older [abstract]. J Clin Oncol 2011;29(Suppl):Abstract 9000.
    • (2011) J Clin Oncol , vol.29 , Issue.SUPPL.
    • Ramsdale, E.E.1    Polite, B.N.2    Bylow, K.A.3
  • 17
    • 84855701468 scopus 로고    scopus 로고
    • Validation of the G8 screening tool in geriatric oncology: The ONCODAGE project
    • [abstract]. Abstract 9001
    • Soubeyran P, Bellera C, Goyard J, et al. Validation of the G8 screening tool in geriatric oncology: the ONCODAGE project [abstract]. J Clin Oncol 2011;29(Suppl):Abstract 9001.
    • (2011) J Clin Oncol , vol.29 , Issue.SUPPL.
    • Soubeyran, P.1    Bellera, C.2    Goyard, J.3
  • 18
    • 72649107196 scopus 로고    scopus 로고
    • Use of a simplified geriatric evaluation in thoracic oncology
    • Cudennec T, Gendry T, Labrune S, et al. Use of a simplified geriatric evaluation in thoracic oncology. Lung Cancer 2010;67:232-236.
    • (2010) Lung Cancer , vol.67 , pp. 232-236
    • Cudennec, T.1    Gendry, T.2    Labrune, S.3
  • 19
    • 79953064531 scopus 로고    scopus 로고
    • The Chemotherapy Risk Assessment Scale for High-Age Patients (CRASH) score: Design and validation
    • [abstract]. Abstract 9000
    • Extermann M, Boler I, Reich R, et al. The Chemotherapy Risk Assessment Scale for High-Age Patients (CRASH) score: design and validation [abstract]. J Clin Oncol 2010;28(Suppl):Abstract 9000.
    • (2010) J Clin Oncol , vol.28 , Issue.SUPPL.
    • Extermann, M.1    Boler, I.2    Reich, R.3
  • 20
    • 80052704591 scopus 로고    scopus 로고
    • Predicting chemotherapy toxicity in older adults with cancer: A prospective multicenter study
    • Hurria A, Togawa K, Mohile SG, et al. Predicting chemotherapy toxicity in older adults with cancer: a prospective multicenter study. J Clin Oncol 2011;29:3457-3465.
    • (2011) J Clin Oncol , vol.29 , pp. 3457-3465
    • Hurria, A.1    Togawa, K.2    Mohile, S.G.3
  • 23
    • 84971581087 scopus 로고
    • Chemotherapy in non-small cell lung cancer: A meta-analysis using updated data on individual patients from 52 randomised clinical trials
    • Non-small Cell Lung Cancer Collaborative Group
    • Chemotherapy in non-small cell lung cancer: a meta-analysis using updated data on individual patients from 52 randomised clinical trials. Non-small Cell Lung Cancer Collaborative Group. BMJ 1995;311:899-909.
    • (1995) BMJ , vol.311 , pp. 899-909
  • 25
    • 84859005517 scopus 로고    scopus 로고
    • Survival and risk of adverse events in older patients receiving postoperative adjuvant chemotherapy for resected stages II-IIIA lung cancer: Observational cohort study
    • Wisnivesky JP, Smith CB, Packer S, et al. Survival and risk of adverse events in older patients receiving postoperative adjuvant chemotherapy for resected stages II-IIIA lung cancer: observational cohort study. BMJ 2011;343:d4013.
    • (2011) BMJ , vol.343
    • Wisnivesky, J.P.1    Smith, C.B.2    Packer, S.3
  • 26
    • 0032794019 scopus 로고    scopus 로고
    • The benefit of treatment intensification is age and histology-dependent in patients with locally advanced non-small cell lung cancer (NSCLC): A quality-adjusted survival analysis of radiation therapy oncology group (RTOG) chemoradiation studies
    • Movsas B, Scott C, Sause W, et al. The benefit of treatment intensification is age and histology-dependent in patients with locally advanced non-small cell lung cancer (NSCLC): a quality-adjusted survival analysis of radiation therapy oncology group (RTOG) chemoradiation studies. Int J Radiat Oncol Biol Phys 1999;45:1143-1149.
    • (1999) Int J Radiat Oncol Biol Phys , vol.45 , pp. 1143-1149
    • Movsas, B.1    Scott, C.2    Sause, W.3
  • 27
    • 0034564180 scopus 로고    scopus 로고
    • Recursive partitioning analysis of 1999 Radiation Therapy Oncology Group (RTOG) patients with locally-advanced non-small-cell lung cancer (LA-NSCLC): Identification of five groups with different survival
    • Werner-Wasik M, Scott C, Cox JD, et al. Recursive partitioning analysis of 1999 Radiation Therapy Oncology Group (RTOG) patients with locally-advanced non-small-cell lung cancer (LA-NSCLC): identification of five groups with different survival. Int J Radiat Oncol Biol Phys 2000;48:1475-1482.
    • (2000) Int J Radiat Oncol Biol Phys , vol.48 , pp. 1475-1482
    • Werner-Wasik, M.1    Scott, C.2    Cox, J.D.3
  • 28
    • 0010028969 scopus 로고    scopus 로고
    • Elderly patients (pts) with locally advanced non-small cell lung cancer (LA-NSCLC) benefit from combined modality therapy: Secondary analysis of Radiation Therapy Oncology Group (RTOG) 94-10
    • [abstract]. Abstract 1193
    • Langer CJ, Hsu C, Curran WJ, et al. Elderly patients (pts) with locally advanced non-small cell lung cancer (LA-NSCLC) benefit from combined modality therapy: secondary analysis of Radiation Therapy Oncology Group (RTOG) 94-10 [abstract]. J Clin Oncol 2002;21(Suppl):Abstract 1193.
    • (2002) J Clin Oncol , vol.21 , Issue.SUPPL.
    • Langer, C.J.1    Hsu, C.2    Curran, W.J.3
  • 30
    • 0036140654 scopus 로고    scopus 로고
    • Therapy choices among older patients with lung carcinoma: An evaluation of two trials of the cancer and leukemia group B
    • DOI 10.1002/cncr.10174
    • Rocha Lima CM, Herndon JE II, Kosty M, et al. Therapy choices among older patients with lung carcinoma: an evaluation of two trials of the Cancer and Leukemia Group B. Cancer 2002;94:181-187. (Pubitemid 34049057)
    • (2002) Cancer , vol.94 , Issue.1 , pp. 181-187
    • Rocha, L.C.M.S.1    Herndon II, J.E.2    Kosty, M.3    Clamon, G.4    Green, M.R.5
  • 35
    • 0037028750 scopus 로고    scopus 로고
    • Cisplatin-based therapy for elderly patients with advanced non-small-cell lung cancer: Implications of Eastern Cooperative Oncology Group 5592, a randomized trial
    • Langer CJ, Manola J, Bernardo P, et al. Cisplatin-based therapy for elderly patients with advanced non-small-cell lung cancer: implications of Eastern Cooperative Oncology Group 5592, a randomized trial. J Natl Cancer Inst 2002;94:173-181. (Pubitemid 34162751)
    • (2002) Journal of the National Cancer Institute , vol.94 , Issue.3 , pp. 173-181
    • Langer, C.J.1    Manola, J.2    Bernardo, P.3    Kugler, J.W.4    Bonomi, P.5    Cella, D.6    Johnson, D.H.7
  • 36
    • 33846985986 scopus 로고    scopus 로고
    • Randomized phase II trial of paclitaxel plus carboplatin or gemcitabine plus cisplatin in Eastern Cooperative Oncology Group performance status 2 non-small-cell lung cancer patients: ECOG 1599
    • DOI 10.1200/JCO.2005.04.9452
    • Langer C, Li S, Schiller J, et al. Randomized phase II trial of paclitaxel plus carboplatin or gemcitabine plus cisplatin in Eastern Cooperative Oncology Group performance status 2 non-small-cell lung cancer patients: ECOG 1599. J Clin Oncol 2007;25:418-423. (Pubitemid 350002990)
    • (2007) Journal of Clinical Oncology , vol.25 , Issue.4 , pp. 418-423
    • Langer, C.J.1    Li, S.2    Schiller, J.3    Tester, W.4    Rapoport, B.L.5    Johnson, D.H.6
  • 37
    • 0035889915 scopus 로고    scopus 로고
    • Outcome of patients with a performance status of 2 in Eastern Cooperative Oncology Group Study E1594: A phase III trial in patients with metastatic nonsmall cell lung carcinoma
    • DOI 10.1002/1097-0142(20011115)92:10<2639::AID-CNCR1617>3.0.CO;2-8
    • Sweeney CJ, Zhu J, Sandler AB, et al. Outcome of patients with a performance status of 2 in Eastern Cooperative Oncology Group Study E1594: a phase II trial in patients with metastatic nonsmall cell lung carcinoma. Cancer 2001;92:2639-2647. (Pubitemid 33049448)
    • (2001) Cancer , vol.92 , Issue.10 , pp. 2639-2647
    • Sweeney, C.J.1    Zhu, J.2    Sandler, A.B.3    Schiller, J.4    Belani, C.P.5    Langer, C.6    Krook, J.7    Harrington, D.8    Johnson, D.H.9
  • 39
    • 0035130402 scopus 로고    scopus 로고
    • The ELVIS trial: A phase III study of single-agent vinorelbine as first-line treatment in elderly patients with advanced non-small cell lung cancer
    • Gridelli C. The ELVIS trial: a phase III study of single-agent vinorelbine as first-line treatment in elderly patients with advanced non-small cell lung cancer. Elderly Lung Cancer Vinorelbine Italian Study. Oncologist 2001;6(Suppl 1):4-7. (Pubitemid 32155180)
    • (2001) Oncologist , vol.6 , Issue.SUPPL. 1 , pp. 4-7
    • Gridelli, C.1
  • 41
    • 0035195433 scopus 로고    scopus 로고
    • Gemcitabine plus vinorelbine yields better survival outcome than vinorelbine alone in elderly patients with advanced non-small cell lung cancer. A Southern Italy Cooperative Oncology Group (SICOG) phase III trial
    • Frasci G, Lorusso V, Panza N, et al. Gemcitabine plus vinorelbine yields better survival outcome than vinorelbine alone in elderly patients with advanced non-small cell lung cancer. A Southern Italy Cooperative Oncology Group (SICOG) phase III trial. Lung Cancer 2001;34(Suppl 4):S65-69.
    • (2001) Lung Cancer , vol.34 , Issue.SUPPL. 4
    • Frasci, G.1    Lorusso, V.2    Panza, N.3
  • 43
    • 80052964872 scopus 로고    scopus 로고
    • Carboplatin and weekly paclitaxel doublet chemotherapy compared with monotherapy in elderly patients with advanced non-small-cell lung cancer: IFCT-0501 randomised, phase 3 trial
    • Quoix E, Zalcman G, Oster JP, et al. Carboplatin and weekly paclitaxel doublet chemotherapy compared with monotherapy in elderly patients with advanced non-small-cell lung cancer: IFCT-0501 randomised, phase 3 trial. Lancet 2011;378:1079-1088.
    • (2011) Lancet , vol.378 , pp. 1079-1088
    • Quoix, E.1    Zalcman, G.2    Oster, J.P.3
  • 44
    • 80052962512 scopus 로고    scopus 로고
    • Randomized phase III trial comparing weekly docetaxel (D)-cisplatin (P) combination with triweekly D alone in elderly patients (pts) with advanced non-small cell lung cancer (NSCLC): An intergroup trial of JCOG0803/WJOG4307L
    • [abstract]. Abstract 7509
    • Abe T, Yokoyama A, Takeda K, et al. Randomized phase III trial comparing weekly docetaxel (D)-cisplatin (P) combination with triweekly D alone in elderly patients (pts) with advanced non-small cell lung cancer (NSCLC): an intergroup trial of JCOG0803/WJOG4307L [abstract]. J Clin Oncol 2011;29(Suppl):Abstract 7509.
    • (2011) J Clin Oncol , vol.29 , Issue.SUPPL.
    • Abe, T.1    Yokoyama, A.2    Takeda, K.3
  • 46
    • 0037648896 scopus 로고    scopus 로고
    • Molecular targeting therapy of cancer: Drug resistance, apoptosis and survival signal
    • DOI 10.1111/j.1349-7006.2003.tb01345.x
    • Tsuruo T, Naito M, Tomida A, et al. Molecular targeting therapy of cancer: drug resistance, apoptosis and survival signal. Cancer Sci 2003;94:15-21. (Pubitemid 36575852)
    • (2003) Cancer Science , vol.94 , Issue.1 , pp. 15-21
    • Tsuruo, T.1    Naito, M.2    Tomida, A.3    Fujita, N.4    Mashima, T.5    Sakamoto, H.6    Haga, N.7
  • 47
    • 62349132009 scopus 로고    scopus 로고
    • Monoclonal antibodies for cancer immunotherapy
    • Weiner LM, Dhodapkar MV, Ferrone S. Monoclonal antibodies for cancer immunotherapy. Lancet 2009;373:1033-1040.
    • (2009) Lancet , vol.373 , pp. 1033-1040
    • Weiner, L.M.1    Dhodapkar, M.V.2    Ferrone, S.3
  • 48
    • 57749188299 scopus 로고    scopus 로고
    • Targeting cancer with small molecule kinase inhibitors
    • Zhang J, Yang PL, Gray NS. Targeting cancer with small molecule kinase inhibitors. Nat Rev Cancer 2009;9:28-39.
    • (2009) Nat Rev Cancer , vol.9 , pp. 28-39
    • Zhang, J.1    Yang, P.L.2    Gray, N.S.3
  • 49
    • 79955660925 scopus 로고    scopus 로고
    • Targeted anti-cancer therapy in the elderly
    • Gonsalves W, Ganti AK. Targeted anti-cancer therapy in the elderly. Crit Rev Oncol Hematol 2011;78:227-242.
    • (2011) Crit Rev Oncol Hematol , vol.78 , pp. 227-242
    • Gonsalves, W.1    Ganti, A.K.2
  • 51
    • 44249121733 scopus 로고    scopus 로고
    • Erlotinib for advanced non-small-cell lung cancer in the elderly: An analysis of the National Cancer Institute of Canada Clinical Trials Group Study BR.21
    • Wheatley-Price P, Ding K, Seymour L, et al. Erlotinib for advanced non-small-cell lung cancer in the elderly: an analysis of the National Cancer Institute of Canada Clinical Trials Group Study BR.21. J Clin Oncol 2008;26:2350-2357.
    • (2008) J Clin Oncol , vol.26 , pp. 2350-2357
    • Wheatley-Price, P.1    Ding, K.2    Seymour, L.3
  • 53
    • 37849052774 scopus 로고    scopus 로고
    • Outcomes for elderly, advanced-stage non small-cell lung cancer patients treated with bevacizumab in combination with carboplatin and paclitaxel: Analysis of Eastern Cooperative Oncology Group Trial 4599
    • Ramalingam SS, Dahlberg SE, Langer CJ, et al. Outcomes for elderly, advanced-stage non small-cell lung cancer patients treated with bevacizumab in combination with carboplatin and paclitaxel: analysis of Eastern Cooperative Oncology Group Trial 4599. J Clin Oncol 2008;26:60-65.
    • (2008) J Clin Oncol , vol.26 , pp. 60-65
    • Ramalingam, S.S.1    Dahlberg, S.E.2    Langer, C.J.3
  • 58
    • 0025221794 scopus 로고
    • Long-term results of operation for non-small cell lung cancer in the elderly
    • Ishida T, Yokoyama H, Kaneko S, et al. Long-term results of operation for non-small cell lung cancer in the elderly. Ann Thorac Surg 1990;50:919-922.
    • (1990) Ann Thorac Surg , vol.50 , pp. 919-922
    • Ishida, T.1    Yokoyama, H.2    Kaneko, S.3
  • 59
    • 0010028969 scopus 로고    scopus 로고
    • Elderly patients with locally advanced non-small cell lung cancer benefit from combined modality therapy: Secondary analysis of Radiation Therapy Oncology Group (RTOG) 94-10
    • [abstract]. Abstract 299a
    • Langer C, Hsu C, Curran WJ, et al. Elderly patients with locally advanced non-small cell lung cancer benefit from combined modality therapy: secondary analysis of Radiation Therapy Oncology Group (RTOG) 94-10 [abstract]. Proc Am Soc Clin Oncol 2002;21:Abstract 299a.
    • (2002) Proc Am Soc Clin Oncol , vol.21
    • Langer, C.1    Hsu, C.2    Curran, W.J.3
  • 60
    • 0000558366 scopus 로고    scopus 로고
    • Should older patients (pts) receive combination chemotherapy for advanced stage non-small cell lung cancer (NSCLC)? An analysis of Southwest Oncology Trials 9509 and 9308
    • [abstract]. Abstract 1313
    • Kelly K, Giaritta S, Akerley W, et al. Should older patients (pts) receive combination chemotherapy for advanced stage non-small cell lung cancer (NSCLC)? An analysis of Southwest Oncology Trials 9509 and 9308 [abstract]. J Clin Oncol 2001;20(Suppl):Abstract 1313.
    • (2001) J Clin Oncol , vol.20 , Issue.SUPPL.
    • Kelly, K.1    Giaritta, S.2    Akerley, W.3
  • 61
    • 0242382971 scopus 로고    scopus 로고
    • Age-specific subanalysis of ECOG 1594: Fit elderly patients (70-80 YRS) with NSCLC do as well as younger pts (<70)
    • [abstract]. Abstract 2571
    • Langer C, Vangel M, Schiller J, et al. Age-specific subanalysis of ECOG 1594: fit elderly patients (70-80 YRS) with NSCLC do as well as younger pts (<70) [abstract]. J Clin Oncol 2003;22(Suppl):Abstract 2571.
    • (2003) J Clin Oncol , vol.22 , Issue.SUPPL.
    • Langer, C.1    Vangel, M.2    Schiller, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.